cis-2-aminocyclopentanecarboxylic acid oligomers adopt a sheetlike structure: Switch from helix to nonpolar strand

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115 Citations (Scopus)


Rational control over helix and strand secondary structures is possible when conformationally restricted cyclic β-amino acid residues are incorporated in the β-peptides. Inversion of the relative configuration of these residues enables the preferred periodic structure to be switched from a helix to a single nonpolar strand (see picture).

Original languageEnglish
Pages (from-to)1718-1721
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number10
Publication statusPublished - jún. 8 2002


ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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