Chiral separation of thiazide diuretics by HPLC on Chiralcel OD-RH®, Chiralcel OJ-R® and Chirobiotic-T™® phases

Balázs Visegrády, Tünde Konecsni, Nina Grobuschek, Martin G. Schmid, Ferenc Kilár, Hassan Y. Aboul-Enein, Gerald Gübitz

Research output: Article

9 Citations (Scopus)

Abstract

This contribution deals with comparative studies on the chiral separation of thiazide diuretics using cellulose tris(3,5-dimethylphenylcarbamate) (Chiralcel OD-RH®), cellulose tris(4-methylbenzoate) (Chiralcel OJ-R®) and teicoplanin (Chirobiotic T™®) phases. All columns showed good chiral recognition ability for this class of compounds. Out of seven compounds investigated, six were resolved with baseline resolution with at least one of the three columns.

Original languageEnglish
Pages (from-to)15-24
Number of pages10
JournalJournal of biochemical and biophysical methods
Volume53
Issue number1-3
DOIs
Publication statusPublished - okt. 1 2002

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry

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