Characterization of human cartilage in degenerated spine disease with differential scanning calorimetry

L. Mécs, Z. Aigner, G. Sohár, Piroska Szabó-Révész, K. Tóth

Research output: Article

3 Citations (Scopus)

Abstract

The purpose of this study was to further characterize the altered metabolism spondylolisthesis that promotes disease progression. Degenerative human cartilage (intervertebral disc, facet joint and vertebral end-plate) was obtained during 15 posterior lumbar spine interbody fusion procedures performed at the University of Szeged. The thermal properties of samples were determined by differential scanning calorimetry (Mettler-Toledo DSC 821 e). Greatest change in the enthalpy was observed in the intervertebral disc samples: -1600.78 J g -1. Denaturation caused by heating in the normal human hyaline cartilage needed -1493.31 J g -1 energy. Characterization of the altered metabolism that promotes disease progression should lead to future treatment options.

Original languageEnglish
Pages (from-to)809-811
Number of pages3
JournalJournal of Thermal Analysis and Calorimetry
Volume95
Issue number3
DOIs
Publication statusPublished - márc. 1 2009

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ASJC Scopus subject areas

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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