A szerotonin a központi idegrendszerben: Kirándulás a neurobiológiától, genetikától a farmakológia, pszichiátria és neurológia felé

G. Bagdy, Filakovszky János, Kántor Sándor, G. Juhász, Graf Márton, R. Jakus, X. Gonda, Zsombók Terézia, C. Ádori, Balogh Brigitta, Kirilly Eszter, Andó Rómeó Dénes, J. Lazáry, Gyöngyösi Norbert, Benko Anita, Molnár Eszter, Kitka Tamás

Research output: Article

1 Citation (Scopus)

Abstract

The widely distributed neurotransmitter serotonin is unquestionably involved in many essential facets of human physiology and behaviour and continues to attract great scientific and public interest. Research related to serotonin became a success story of pharmacology, neurology and psychiatry and other biomedical fields. Several drugs that led to the revolution of the pharmacotherapy of depression, anxiety disorders, schizophrenia, migraine, irritable bowel disease or vomiting act on the serotonergic neurotransmission. The first part of this article gives a short summary of our current knowledge about serotonin, namely anatomy, receptors, functions and drugs used in therapy. In the second part the authors focussed on the results of the last ten year research in selected serotonin-related fields achieved by the Laboratory of Neurochemistry and Experimental Medicine of the previous National Institute of Psychiatry and Neurology and it's successor at Semmelweis University. These include preclinical and clinical works in the fields of neurosciences and pharmacology, namely migraine, epilepsy, anxiety, depression, sleep regulation and the morphological and functional effects of ecstasy (3,4- methylenedioxymethamphetamine, MDMA).

Original languageHungarian
Pages (from-to)73-92
Number of pages20
JournalOrvoskepzes
Volume84
Issue numberSUPPL. 2
Publication statusPublished - 2009

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Neurobiology
Neurology
Psychiatry
Serotonin
Central Nervous System
Pharmacology
Migraine Disorders
Depression
Neurochemistry
Drug Receptors
N-Methyl-3,4-methylenedioxyamphetamine
Neurosciences
Anxiety Disorders
Research
Synaptic Transmission
Vomiting
Neurotransmitter Agents
Biomedical Research
Epilepsy
Anatomy

Keywords

  • 5-HT receptors
  • Anxiety
  • Cellular signals
  • CGRP
  • Depression
  • Drug therapy
  • Ecstasy
  • Epilepsy
  • Gene × environment interaction
  • Genetic polymorphism
  • MDMA
  • Migraine
  • Neuronal damage
  • Serotonin (5-HT)
  • Serotonintransporter
  • Sleep

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A szerotonin a központi idegrendszerben : Kirándulás a neurobiológiától, genetikától a farmakológia, pszichiátria és neurológia felé. / Bagdy, G.; János, Filakovszky; Sándor, Kántor; Juhász, G.; Márton, Graf; Jakus, R.; Gonda, X.; Terézia, Zsombók; Ádori, C.; Brigitta, Balogh; Eszter, Kirilly; Dénes, Andó Rómeó; Lazáry, J.; Norbert, Gyöngyösi; Anita, Benko; Eszter, Molnár; Tamás, Kitka.

In: Orvoskepzes, Vol. 84, No. SUPPL. 2, 2009, p. 73-92.

Research output: Article

Bagdy, G, János, F, Sándor, K, Juhász, G, Márton, G, Jakus, R, Gonda, X, Terézia, Z, Ádori, C, Brigitta, B, Eszter, K, Dénes, AR, Lazáry, J, Norbert, G, Anita, B, Eszter, M & Tamás, K 2009, 'A szerotonin a központi idegrendszerben: Kirándulás a neurobiológiától, genetikától a farmakológia, pszichiátria és neurológia felé', Orvoskepzes, vol. 84, no. SUPPL. 2, pp. 73-92.
Bagdy, G. ; János, Filakovszky ; Sándor, Kántor ; Juhász, G. ; Márton, Graf ; Jakus, R. ; Gonda, X. ; Terézia, Zsombók ; Ádori, C. ; Brigitta, Balogh ; Eszter, Kirilly ; Dénes, Andó Rómeó ; Lazáry, J. ; Norbert, Gyöngyösi ; Anita, Benko ; Eszter, Molnár ; Tamás, Kitka. / A szerotonin a központi idegrendszerben : Kirándulás a neurobiológiától, genetikától a farmakológia, pszichiátria és neurológia felé. In: Orvoskepzes. 2009 ; Vol. 84, No. SUPPL. 2. pp. 73-92.
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