Cardiovascular risk factors differently affect the survival of patients undergoing manual or mechanical resuscitation 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology

Dóra Ujvárosy, Veronika Sebestyén, Tamás Pataki, Tamás Ötvös, István Lorincz, György Paragh, Z. Szabó

Research output: Article

Abstract

Background: Chest compression is a decisive element of cardio-pulmonary resuscitation (CPR). By applying a mechanical CPR device, compression interruptions can be minimised. We examined the efficiency of manual and device-assisted resuscitation as well as the effects of cardiovascular risk factors on the outcome of resuscitation. Methods: In our retrospective, randomised 3-year study the data of adult patients suffering non-traumatic, out-of-hospital, sudden cardiac death (SCD) were analysed (n = 287). The data were retrieved by processing case reports, Utstein sheets and acute coronary syndrome sheets. We compared the data of patients undergoing manual (n = 232) and device-assisted resuscitation (LUCAS-2, n = 55). The primary endpoint was the on-site restoration of spontaneous circulation (ROSC). Results and conclusion: In 37% of the cases ROSC happened. With respect to ROSC an insignificantly more favourable tendency was demonstrated in the case of device-assisted resuscitation (p = 0.072). In the Lucas group, a higher success rate occurred even in the case of prolonged resuscitation. We found a better outcome in the Lucas group in the case of CPR started a longer time after the SCD (p < 0.05). A positive correlation was established between age and unsuccessful resuscitation (p = < 0.017; r = 0.125). An unfavourable correlation was observed between hypertension and the outcome of resuscitation (p = 0.018; r = 0.143). According to our results the presence of left ventricular hypertrophy poses 5.1-fold risk of unsuccessful CPR (CI: 4.97-5.29). Advanced age and structural heart diseases can play a role in the genesis of SCD. Importantly, left ventricular hypertrophy and hypertension negatively affect survival.

Original languageEnglish
Article number277
JournalBMC Cardiovascular Disorders
Volume18
Issue number1
DOIs
Publication statusPublished - dec. 7 2018

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Hematology
Resuscitation
Medicine
Cardiopulmonary Resuscitation
Survival
Health
Sudden Cardiac Death
Equipment and Supplies
Left Ventricular Hypertrophy
Hypertension
Acute Coronary Syndrome
Heart Diseases
Thorax

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Cardiovascular risk factors differently affect the survival of patients undergoing manual or mechanical resuscitation 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology. / Ujvárosy, Dóra; Sebestyén, Veronika; Pataki, Tamás; Ötvös, Tamás; Lorincz, István; Paragh, György; Szabó, Z.

In: BMC Cardiovascular Disorders, Vol. 18, No. 1, 277, 07.12.2018.

Research output: Article

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AU - Sebestyén, Veronika

AU - Pataki, Tamás

AU - Ötvös, Tamás

AU - Lorincz, István

AU - Paragh, György

AU - Szabó, Z.

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AB - Background: Chest compression is a decisive element of cardio-pulmonary resuscitation (CPR). By applying a mechanical CPR device, compression interruptions can be minimised. We examined the efficiency of manual and device-assisted resuscitation as well as the effects of cardiovascular risk factors on the outcome of resuscitation. Methods: In our retrospective, randomised 3-year study the data of adult patients suffering non-traumatic, out-of-hospital, sudden cardiac death (SCD) were analysed (n = 287). The data were retrieved by processing case reports, Utstein sheets and acute coronary syndrome sheets. We compared the data of patients undergoing manual (n = 232) and device-assisted resuscitation (LUCAS-2, n = 55). The primary endpoint was the on-site restoration of spontaneous circulation (ROSC). Results and conclusion: In 37% of the cases ROSC happened. With respect to ROSC an insignificantly more favourable tendency was demonstrated in the case of device-assisted resuscitation (p = 0.072). In the Lucas group, a higher success rate occurred even in the case of prolonged resuscitation. We found a better outcome in the Lucas group in the case of CPR started a longer time after the SCD (p < 0.05). A positive correlation was established between age and unsuccessful resuscitation (p = < 0.017; r = 0.125). An unfavourable correlation was observed between hypertension and the outcome of resuscitation (p = 0.018; r = 0.143). According to our results the presence of left ventricular hypertrophy poses 5.1-fold risk of unsuccessful CPR (CI: 4.97-5.29). Advanced age and structural heart diseases can play a role in the genesis of SCD. Importantly, left ventricular hypertrophy and hypertension negatively affect survival.

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