Carbohydrate metabolism and cardiovascular risk factors 4 years after a pregnancy complicated by gestational diabetes

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Abstract

Aims: The aim of the present study was to determine the prevalence of abnormal glucose tolerance and the metabolic syndrome in a cohort of previously gestational diabetic (GDM) women 4 years after delivery. Methods: Sixty-eight prior GDM and a control group of 39 women with normal glucose tolerance during pregnancy were invited to participate in a follow-up study. Results: The prevalence of diabetes, impaired glucose tolerance and impaired fasting glucose (IFG) was 21%, 16%, and 6% among prior GDM women and 0%, 15%, and 0% among controls respectively (P = 0.0039). Independently of the metabolic syndrome criteria used this status was found more frequently among women with prior GDM (all P < 0.05). The prevalence of the metabolic syndrome showed a dose-response relationship with the level of weight categories (P < 0.005) as well as with the level of glucose intolerance (P = 0.024). Conclusion: According to our results a disturbed carbohydrate metabolism and a clustering of cardiovascular risk factors might be observed in previous GDM women 4 years after delivery.

Original languageEnglish
Pages (from-to)197-202
Number of pages6
JournalDiabetes Research and Clinical Practice
Volume85
Issue number2
DOIs
Publication statusPublished - aug. 1 2009

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ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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