Calcium-containing mitochondrial granules in neurohypophysial axon terminals disappear following vasopressin treatment of brattleboro rats

Sarolta Karcsú, F. László, Lajos Tóth, G. Jancsó, Ernö Bácsy

Research output: Article

8 Citations (Scopus)

Abstract

The presence of intramitochondrial calcium-containing electron-dense granules was demonstrated in axon terminals of chronically hyperactive neurosecretory neurons of untreated homozygous Brattleboro rats. Following vasopressin treatment for 30 days, which has been shown to attenuate this neuronal hyperactivity, calcium-containing deposits could not be detected in mitochondria. It is concluded that the presence of intramitochondrial calcium-containing dense deposits is connected with the functional state of neurosecretory neurons.

Original languageEnglish
Pages (from-to)181-185
Number of pages5
JournalNeuroscience Letters
Volume39
Issue number2
DOIs
Publication statusPublished - aug. 29 1983

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Brattleboro Rats
Presynaptic Terminals
Vasopressins
Calcium
Neurons
Mitochondria
Electrons

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

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title = "Calcium-containing mitochondrial granules in neurohypophysial axon terminals disappear following vasopressin treatment of brattleboro rats",
abstract = "The presence of intramitochondrial calcium-containing electron-dense granules was demonstrated in axon terminals of chronically hyperactive neurosecretory neurons of untreated homozygous Brattleboro rats. Following vasopressin treatment for 30 days, which has been shown to attenuate this neuronal hyperactivity, calcium-containing deposits could not be detected in mitochondria. It is concluded that the presence of intramitochondrial calcium-containing dense deposits is connected with the functional state of neurosecretory neurons.",
keywords = "Brattleboro rat, calcium, cytochemistry, neurohypophysis, neuronal activity, vasopressin treatment, X-ray microanalysis",
author = "Sarolta Karcs{\'u} and F. L{\'a}szl{\'o} and Lajos T{\'o}th and G. Jancs{\'o} and Ern{\"o} B{\'a}csy",
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T1 - Calcium-containing mitochondrial granules in neurohypophysial axon terminals disappear following vasopressin treatment of brattleboro rats

AU - Karcsú, Sarolta

AU - László, F.

AU - Tóth, Lajos

AU - Jancsó, G.

AU - Bácsy, Ernö

PY - 1983/8/29

Y1 - 1983/8/29

N2 - The presence of intramitochondrial calcium-containing electron-dense granules was demonstrated in axon terminals of chronically hyperactive neurosecretory neurons of untreated homozygous Brattleboro rats. Following vasopressin treatment for 30 days, which has been shown to attenuate this neuronal hyperactivity, calcium-containing deposits could not be detected in mitochondria. It is concluded that the presence of intramitochondrial calcium-containing dense deposits is connected with the functional state of neurosecretory neurons.

AB - The presence of intramitochondrial calcium-containing electron-dense granules was demonstrated in axon terminals of chronically hyperactive neurosecretory neurons of untreated homozygous Brattleboro rats. Following vasopressin treatment for 30 days, which has been shown to attenuate this neuronal hyperactivity, calcium-containing deposits could not be detected in mitochondria. It is concluded that the presence of intramitochondrial calcium-containing dense deposits is connected with the functional state of neurosecretory neurons.

KW - Brattleboro rat

KW - calcium

KW - cytochemistry

KW - neurohypophysis

KW - neuronal activity

KW - vasopressin treatment

KW - X-ray microanalysis

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