Biology of porcine parvovirus (Ungulate parvovirus 1)

István Mészáros, F. Olasz, Attila Cságola, Peter Tijssen, Z. Zádori

Research output: Review article

7 Citations (Scopus)

Abstract

Porcine parvovirus (PPV) is among the most important infectious agents causing infertility in pigs. Until recently, it was thought that the virus had low genetic variance, and that prevention of its harmful effect on pig fertility could be well-controlled by vaccination. However, at the beginning of the third millennium, field observations raised concerns about the effectiveness of the available vaccines against newly emerging strains. Subsequent investigations radically changed our view on the evolution and immunology of PPV, revealing that the virus is much more diverse than it was earlier anticipated, and that some of the “new” highly virulent isolates cannot be neutralized effectively by antisera raised against “old” PPV vaccine strains. These findings revitalized PPV research that led to significant advancements in the understanding of early and late viral processes during PPV infection. Our review summarizes the recent results of PPV research and aims to give a comprehensive update on the present understanding of PPV biology.

Original languageEnglish
Article number393
JournalViruses
Volume9
Issue number12
DOIs
Publication statusPublished - dec. 20 2017

Fingerprint

Porcine Parvovirus
Parvovirus
Swine
Vaccines
Fertility Agents
Viruses
Parvoviridae Infections
Allergy and Immunology
Research
Fertility
Immune Sera
Vaccination

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology

Cite this

Biology of porcine parvovirus (Ungulate parvovirus 1). / Mészáros, István; Olasz, F.; Cságola, Attila; Tijssen, Peter; Zádori, Z.

In: Viruses, Vol. 9, No. 12, 393, 20.12.2017.

Research output: Review article

Mészáros, István ; Olasz, F. ; Cságola, Attila ; Tijssen, Peter ; Zádori, Z. / Biology of porcine parvovirus (Ungulate parvovirus 1). In: Viruses. 2017 ; Vol. 9, No. 12.
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