Elörehaladott perifériás artériás érbetegségben szenvedok kezelése autológ csontveloi, vagy periférias vérbol származó ossejtekkel

Zoltán Boda, Zoltán Veréb, Éva Rajnavolgji

Research output: Article

2 Citations (Scopus)

Abstract

No effective medical therapies have been developed sofar to enhance blood flow in the legs of patients with peripheral arterial disease (PAD). For patients with limb threatening ischaemia the only option for relief of rest pain or gangraena is amputation. There is evidence in experimental and clinical studies that adult bone marrow-derived stem cells and endothelial progenitor cells participate in the development of new blood vessels, called neoangiogenesis or neovascularization. Clinical results induced by autologous bone marrow stem cells or angiogenic growth/differentiation factors in end-stage patients with PAD are summarized. Considering the relatively few number of patients treated by angiogenic therapy, the interpretation of clinical results needs cautiousness.

Translated title of the contributionAutologous bone marrow stem cell or peripheral blood endothelial progenitor cell therapy in patients with peripheral ischaemia
Original languageHungarian
Pages (from-to)1155-1160
Number of pages6
JournalOrvosi hetilap
Volume147
Issue number25
Publication statusPublished - jún. 25 2006

Keywords

  • Angiogenic growth/differentiation factor
  • Autologous stem-cell therapy
  • Endothelial progenitor cell
  • Peripheral arterial disorder

ASJC Scopus subject areas

  • Medicine(all)

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