Atomic force microscopy of height fluctuations of fibroblast cells

Bálint Szabó, Dávid Selmeczi, Zsuzsanna Környei, Emília Madarász, Noémi Rozlosnik

Research output: Article

22 Citations (Scopus)


We investigated the nanometer scale height fluctuations of 3T3 fibroblast cells with the atomic force microscope under physiological conditions. A correlation between these fluctuations and lateral cellular motility can be observed. Fluctuations measured on leading edges appear to be predominantly related to actin polymerization-depolymerization processes. We found fast (5 Hz) pulsatory behavior with 1-2 nm amplitude on a cell with low motility showing emphasized structure of stress fibers. Myosin driven contractions of stress fibers are thought to induce this pulsation.

Original languageEnglish
Article number041910
Pages (from-to)041910/1-041910/6
JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
Issue number4
Publication statusPublished - ápr. 1 2002

ASJC Scopus subject areas

  • Statistical and Nonlinear Physics
  • Statistics and Probability
  • Condensed Matter Physics

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