Association of extraintestinal manifestations and anaemia with disease outcomes in patients with inflammatory bowel disease

Zsuzsanna Vegh, Zsuzsanna Kurti, Lorant Gonczi, Petra Anna Golovics, Barbara Dorottya Lovasz, Istvan Szita, Mihaly Balogh, T. Pandúr, Stephan R. Vavricka, Gerhard Rogler, L. Lakatos, P. Lakatos

Research output: Article

12 Citations (Scopus)

Abstract

Objective The association between extraintestinal manifestations (EIMs) and disease activity suggest a common pathogenetic link with inflammatory bowel disease (IBD). We report on the association of EIMs and anaemia with long-term disease outcomes, including treatment steps, hospitalization, and surgery in the prospective population-based IBD inception cohort from Veszprem province. Methods Data of 678 incident IBD patients (Crohn’s disease/ulcerative colitis(CD/UC): 331/347) diagnosed from 1st January 2000 to 31st December 2012 were analyzed (CD: m/f: 176/155, median age at diagnosis: 28, IQR: 21–40 years, disease duration: 6, IQR: 2–9 years; UC: m/f: 200/147, median age at diagnosis: 36, IQR: 26–50 years, duration: 7, IQR: 4–10 years). Results EIMs were present in 30% of the CD and 17.3% of the UC patients. In CD, female gender (p = 0.02) need for steroid (p  CD = 0.001, pUC = 0.04), disease location/extent (pCD = 0.02, pUC CD,UC CD UC = 0.002) and hospitalization (pCD = 0.004, pUC

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalScandinavian Journal of Gastroenterology
DOIs
Publication statusAccepted/In press - febr. 11 2016

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Inflammatory Bowel Diseases
Anemia
Hospitalization
Ulcerative Colitis
Crohn Disease
Steroids
Population

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Association of extraintestinal manifestations and anaemia with disease outcomes in patients with inflammatory bowel disease. / Vegh, Zsuzsanna; Kurti, Zsuzsanna; Gonczi, Lorant; Golovics, Petra Anna; Lovasz, Barbara Dorottya; Szita, Istvan; Balogh, Mihaly; Pandúr, T.; Vavricka, Stephan R.; Rogler, Gerhard; Lakatos, L.; Lakatos, P.

In: Scandinavian Journal of Gastroenterology, 11.02.2016, p. 1-7.

Research output: Article

Vegh, Zsuzsanna ; Kurti, Zsuzsanna ; Gonczi, Lorant ; Golovics, Petra Anna ; Lovasz, Barbara Dorottya ; Szita, Istvan ; Balogh, Mihaly ; Pandúr, T. ; Vavricka, Stephan R. ; Rogler, Gerhard ; Lakatos, L. ; Lakatos, P. / Association of extraintestinal manifestations and anaemia with disease outcomes in patients with inflammatory bowel disease. In: Scandinavian Journal of Gastroenterology. 2016 ; pp. 1-7.
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abstract = "Objective The association between extraintestinal manifestations (EIMs) and disease activity suggest a common pathogenetic link with inflammatory bowel disease (IBD). We report on the association of EIMs and anaemia with long-term disease outcomes, including treatment steps, hospitalization, and surgery in the prospective population-based IBD inception cohort from Veszprem province. Methods Data of 678 incident IBD patients (Crohn’s disease/ulcerative colitis(CD/UC): 331/347) diagnosed from 1st January 2000 to 31st December 2012 were analyzed (CD: m/f: 176/155, median age at diagnosis: 28, IQR: 21–40 years, disease duration: 6, IQR: 2–9 years; UC: m/f: 200/147, median age at diagnosis: 36, IQR: 26–50 years, duration: 7, IQR: 4–10 years). Results EIMs were present in 30{\%} of the CD and 17.3{\%} of the UC patients. In CD, female gender (p = 0.02) need for steroid (p  CD = 0.001, pUC = 0.04), disease location/extent (pCD = 0.02, pUC CD,UC CD UC = 0.002) and hospitalization (pCD = 0.004, pUC ",
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AU - Lovasz, Barbara Dorottya

AU - Szita, Istvan

AU - Balogh, Mihaly

AU - Pandúr, T.

AU - Vavricka, Stephan R.

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AB - Objective The association between extraintestinal manifestations (EIMs) and disease activity suggest a common pathogenetic link with inflammatory bowel disease (IBD). We report on the association of EIMs and anaemia with long-term disease outcomes, including treatment steps, hospitalization, and surgery in the prospective population-based IBD inception cohort from Veszprem province. Methods Data of 678 incident IBD patients (Crohn’s disease/ulcerative colitis(CD/UC): 331/347) diagnosed from 1st January 2000 to 31st December 2012 were analyzed (CD: m/f: 176/155, median age at diagnosis: 28, IQR: 21–40 years, disease duration: 6, IQR: 2–9 years; UC: m/f: 200/147, median age at diagnosis: 36, IQR: 26–50 years, duration: 7, IQR: 4–10 years). Results EIMs were present in 30% of the CD and 17.3% of the UC patients. In CD, female gender (p = 0.02) need for steroid (p  CD = 0.001, pUC = 0.04), disease location/extent (pCD = 0.02, pUC CD,UC CD UC = 0.002) and hospitalization (pCD = 0.004, pUC 

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