Antiviral activity of tiazofurine against barley stripe mosaic virus

P. D. Nagy, R. Gáborjányi, L. Kovács, I. Farkas

Research output: Article

7 Citations (Scopus)


Tiazofurine (2-β-D-ribofuranosylthiazole-4-carboxamide) was found to inhibit replication of barley stripe mosaic virus (BSMV) in barley and wheat plants. Treatment with this nucleoside analogue delayed and inhibited symptom development and suppressed virus multiplication. The most effective concentration applied twice as a foliar spray 3 h and one day after inoculation, was 10-3 M. Decreased virus multiplication was obtained without marked phytotoxicity. Three weeks after treatment the antiviral effect declined.

Original languageEnglish
Pages (from-to)41-45
Number of pages5
JournalAntiviral Research
Issue number1
Publication statusPublished - febr. 1989


ASJC Scopus subject areas

  • Pharmacology
  • Virology

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