An ice-Cold TR(i)P to skin biology: The role of TRPA1 in human epidermal keratinocytes

Tamás Bíró, László Kovács

Research output: Comment/debate

22 Citations (Scopus)

Abstract

Recent studies have suggested the expression of numerous heat-sensitive transient receptor potential (TRP) ion channels in non-neuronal cell populations of the skin. In this issue, Atoyan et al. provide evidence that the noxious cold-activated TRPA1 is widely expressed in various human cutaneous cells and that it may be directly involved in the regulation of keratinocyte proliferation and differentiation and in cutaneous inflammatory responses.

Original languageEnglish
Pages (from-to)2096-2099
Number of pages4
JournalJournal of Investigative Dermatology
Volume129
Issue number9
DOIs
Publication statusPublished - szept. 2009

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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