Amorfizálás a gyógyszer-technológiában

Piroska Révész, Orsolya Laczkovich, István Eros

Research output: Review article

2 Citations (Scopus)


The amorphization of crystalline active ingredients may be necessary because of the polymorphism of the active substance, the poor water-solubility of the drug material, difficult processing in the crystalline form and the taking out of a patent for a new (amorphous) form. This article introduces protocols for amorphization, which use methods traditionally applied in pharmaceutical technology. The protocols involve three possible routes: solvent methods, hot-melt technologies and milling procedures. With this presentation, the authors suggest help for practising experts to find the correct amorphization method.

Translated title of the contributionAmorphization in pharmaceutical technology
Original languageHungarian
Pages (from-to)39-44
Number of pages6
JournalActa pharmaceutica Hungarica
Issue number1
Publication statusPublished - máj. 14 2004

ASJC Scopus subject areas

  • Pharmaceutical Science

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