Allogen transzplantacio periferias haemopoeticus ossejtekkel

Research output: Article

Abstract

Over the past few years there have been major advances in the use of peripheral blood stem cells as an alternative to bone marrow in transplantation. Initially these efforts have been focused on autologuos transplants. However the application of peripheral blood stem cell transplantation has now been extended to the allogeneic setting. Adequate mobilization with minimal side-effects can be achieved in normal donors using a short course of granulocyte colony stimulating factor. Allogeneic peripheral stem cells provide long-term engraftment that appears to be more rapid than that has been observed with marrow. The cellular composition of blood cell and marrow allografts is very different. Although the amount of infused T-cells is increased, no difference in acute graft versus host disease has been documented. Allogeneic stem cell transplantation seems to be a viable alternative to bone marrow transplantation and probably will expand both in matched sibling and in mismatched transplantation.

Original languageHungarian
Pages (from-to)42-45
Number of pages4
JournalLege Artis Medicinae
Volume7
Issue number1-2
Publication statusPublished - 1997

Fingerprint

Peripheral Blood Stem Cell Transplantation
Bone Marrow Transplantation
Bone Marrow
Stem Cell Transplantation
Graft vs Host Disease
Granulocyte Colony-Stimulating Factor
Allografts
Blood Cells
Transplantation
T-Lymphocytes
Transplants
Peripheral Blood Stem Cells

Keywords

  • Allogeneic
  • Engraftment
  • G-CSF
  • GM-CSF
  • GVF
  • Haematopoetic stem cell
  • Peripheral blood stem cell transplantation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Allogen transzplantacio periferias haemopoeticus ossejtekkel. / Masszi, T.

In: Lege Artis Medicinae, Vol. 7, No. 1-2, 1997, p. 42-45.

Research output: Article

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