Advanced methods for the synthesis of 3-substituted 1H-isoindol-1-ones

Génes Stájer, Ferenc Csende

Research output: Article

31 Citations (Scopus)

Abstract

Both direct and multistep reactions, involving the application of carbonyl compounds, e. g. oxoacids, phthalimides, 2-iodobenzamides or acylhatides, have been developed as novel synthetic routes for the preparation of 3-substituted 2,3-dihydro-1H-isoindol-1-ones, which are reviewed here. Alternatively, reductive or acid-catalyzed rearrangements of certain heterocycles lead to the formation of 3-substituted isoindolones. Asymmetric syntheses too have been described.

Original languageEnglish
Pages (from-to)1277-1286
Number of pages10
JournalCurrent Organic Chemistry
Volume9
Issue number13
DOIs
Publication statusPublished - szept. 2005

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Phthalimides
Keto Acids
Carbonyl compounds
Acids
Isoindol-1-one
1-oxoisoindole

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Advanced methods for the synthesis of 3-substituted 1H-isoindol-1-ones. / Stájer, Génes; Csende, Ferenc.

In: Current Organic Chemistry, Vol. 9, No. 13, 09.2005, p. 1277-1286.

Research output: Article

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