Acne: Transient Arrest in the Homeostatic Host–Microbiota Dialog?

Research output: Short survey

Abstract

We propose that acne vulgaris represents a naturally developing, transient inflammatory interaction of adolescent facial skin with its new microbial/chemical milieu (Cutibacterium acnes, sebum), replacing a state of previous childhood skin homeostasis. This concept might explain why acne is characterized by strong regional and age specificity, prevalent occurrence, and resolution.

Original languageEnglish
Pages (from-to)873-876
Number of pages4
JournalTrends in Immunology
Volume40
Issue number10
DOIs
Publication statusPublished - okt. 2019

Fingerprint

Acne Vulgaris
Sebum
Skin
Homeostasis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

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title = "Acne: Transient Arrest in the Homeostatic Host–Microbiota Dialog?",
abstract = "We propose that acne vulgaris represents a naturally developing, transient inflammatory interaction of adolescent facial skin with its new microbial/chemical milieu (Cutibacterium acnes, sebum), replacing a state of previous childhood skin homeostasis. This concept might explain why acne is characterized by strong regional and age specificity, prevalent occurrence, and resolution.",
keywords = "acne, Cutibacterium acnes, homeostasis, inflammation, microbiota, sebum",
author = "Andrea Szegedi and Zsolt Dajnoki and Tam{\'a}s B{\'i}r{\'o} and Lajos Kem{\'e}ny and D{\'a}niel T{\"o}rőcsik",
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AU - Dajnoki, Zsolt

AU - Bíró, Tamás

AU - Kemény, Lajos

AU - Törőcsik, Dániel

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KW - inflammation

KW - microbiota

KW - sebum

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