A novel passerivirus (family Picornaviridae) in an outbreak of enteritis with high mortality in estrildid finches (Uraeginthus sp.)

P. Pankovics, Ákos Boros, Tung Gia Phan, Eric Delwart, G. Reuter

Research output: Article

1 Citation (Scopus)

Abstract

An enteric outbreak with high mortality (34/52, 65.4%) was recorded in 2014 in home-reared estrildid finches (Estrildidae) in Hungary. A novel passerivirus was identified in a diseased violet-eared waxbill using viral metagenomics and confirmed by RT-(q)PCR. The complete genome of finch picornavirus strain waxbill/DB01/HUN/2014 (MF977321) showed the highest amino acid sequence identity of 38.9%, 61.6%, 69.6% in P1cap, 2Chel and 3CproDpol, respectively, to passerivirus A1 (GU182406). A high viral load (6.58 × 1010 genomic copies/ml) was measured in a cloacal specimen and in the tissues (spinal cord, lung, and the intestines) of two additional affected finches. In addition to intestinal symptoms (diarrhoea), the presence of extra-intestinal virus suggests a generalized infection in this fatal disease, for which the passerivirus might be a causative agent.

Original languageEnglish
Pages (from-to)1063-1071
Number of pages9
JournalArchives of Virology
Volume163
Issue number4
DOIs
Publication statusPublished - ápr. 1 2018

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Picornaviridae
Finches
Enteritis
Disease Outbreaks
Mortality
Viola
Metagenomics
Hungary
Viral Load
Intestines
Amino Acid Sequence
Diarrhea
Spinal Cord
Genome
Viruses
Polymerase Chain Reaction
Lung
Infection

ASJC Scopus subject areas

  • Virology

Cite this

A novel passerivirus (family Picornaviridae) in an outbreak of enteritis with high mortality in estrildid finches (Uraeginthus sp.). / Pankovics, P.; Boros, Ákos; Phan, Tung Gia; Delwart, Eric; Reuter, G.

In: Archives of Virology, Vol. 163, No. 4, 01.04.2018, p. 1063-1071.

Research output: Article

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