A facile synthesis of 3-(substituted benzyl)piperidines

Béla Ágai, Adrienn Nádor, Ágnes Proszenyák, Gábor Tárkányi, Ferenc Faigl

Research output: Article

10 Citations (Scopus)

Abstract

A convenient new method has been developed for preparation a series of 3-(substituted benzyl)piperidines by addition of substituted phenylmagnesium bromide to pyridine-3-carboxaldehyde followed by one pot deoxygenation and heteroaromatic ring saturation in the presence of palladium catalyst.

Original languageEnglish
Pages (from-to)7897-7900
Number of pages4
JournalTetrahedron
Volume59
Issue number40
DOIs
Publication statusPublished - szept. 29 2003

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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