A diarrheic chicken simultaneously co-infected with multiple picornaviruses: Complete genome analysis of avian picornaviruses representing up to six genera

Ákos Boros, P. Pankovics, Ádám Adonyi, Hajnalka Fenyvesi, J. Michael Day, Tung Gia Phan, Eric Delwart, G. Reuter

Research output: Article

10 Citations (Scopus)

Abstract

In this study all currently known chicken picornaviruses including a novel one (chicken phacovirus 1, KT880670) were identified by viral metagenomic and RT-PCR methods from a single specimen of a diarrheic chicken suffering from a total of eight picornavirus co-infections, in Hungary. The complete genomes of six picornaviruses were determined and their genomic and phylogenetic characteristics and UTR RNA structural models analyzed in details. Picornaviruses belonged to genera Sicinivirus (the first complete genome), Gallivirus, Tremovirus, Avisivirus and "Orivirus" (two potential genotypes). In addition, the unassigned phacoviruses were also detected in multiple samples of chickens in the USA. Multiple co-infections promote and facilitate the recombination and evolution of picornaviruses and eventually could contribute to the severity of the diarrhea in chicken, in one of the most important food sources of humans.

Original languageEnglish
Pages (from-to)63-74
Number of pages12
JournalVirology
Volume489
DOIs
Publication statusPublished - febr. 1 2016

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Picornaviridae
Chickens
Genome
Coinfection
Picornaviridae Infections
Untranslated Regions
Metagenomics
Hungary
Structural Models
Genetic Recombination
Diarrhea
Genotype
RNA
Food
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Virology

Cite this

A diarrheic chicken simultaneously co-infected with multiple picornaviruses : Complete genome analysis of avian picornaviruses representing up to six genera. / Boros, Ákos; Pankovics, P.; Adonyi, Ádám; Fenyvesi, Hajnalka; Day, J. Michael; Phan, Tung Gia; Delwart, Eric; Reuter, G.

In: Virology, Vol. 489, 01.02.2016, p. 63-74.

Research output: Article

Boros, Ákos ; Pankovics, P. ; Adonyi, Ádám ; Fenyvesi, Hajnalka ; Day, J. Michael ; Phan, Tung Gia ; Delwart, Eric ; Reuter, G. / A diarrheic chicken simultaneously co-infected with multiple picornaviruses : Complete genome analysis of avian picornaviruses representing up to six genera. In: Virology. 2016 ; Vol. 489. pp. 63-74.
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