A De Novo Synthetic Route to 1,2,3,4-Tetrahydroisoquinoline Derivatives

Renáta A. Ábrahámi, Santos Fustero, F. Fülöp, L. Kiss

Research output: Article

3 Citations (Scopus)

Abstract

A novel synthetic approach was developed for the construction of the 1,2,3,4-tetrahydroisoquinoline framework possessing varied functions. The synthetic strategy was based on oxidative ring opening of some indene derivatives through their C=C bond, followed by double reductive amination of the dicarbonyl intermediates with various primary alkyl- or fluoroalkylamines.

Original languageEnglish
JournalSynlett
DOIs
Publication statusAccepted/In press - márc. 22 2018

ASJC Scopus subject areas

  • Organic Chemistry

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