A convenient regioselective synthesis of pyrano[3,2-b]acridones involving nucleophilic addition to benzyne

Mónika Rudas, Miklós Nyerges, László Töke, Béla Pete, Paul W. Groundwater

Research output: Article

14 Citations (Scopus)


Acridone 8 was prepared by the nucleophilic addition of aniline 4 to benzyne 5. Hydrolysis of the ester group, followed by cyclisation gave the acridone 8, which was subsequently converted to the pyrano[3,2-b]acridin-4-ones 11 and 17.

Original languageEnglish
Pages (from-to)7003-7006
Number of pages4
JournalTetrahedron Letters
Issue number38
Publication statusPublished - szept. 17 1999


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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