9-(6-DEOXY- β-D-Allofuranosyl)Adenine Cyclic 3 1, 5 ‘-Phosphor-Amidate: A New Cyclic Amp Amide Derivative Containing an Equatorial Methyl Group at the 5'-Position

L. Radies, S. Bottka, J. Tomasz

Research output: Article

1 Citation (Scopus)

Abstract

Rp and Sp phosphorus diastereoisomers of the title — compound (2; are prepared from the corresponding cyclic monophosphte. Solution conformation of the dioxaphosphor-inane ring and hydrolysis of RP-2 and Sp-2 are studied and compared with those of the phosphorus diastereoisomers of the isomeric compound that contains the 5’-methyl group in the axial position.

Original languageEnglish
Pages (from-to)1305-1317
Number of pages13
JournalNucleosides and Nucleotides
Volume8
Issue number7
DOIs
Publication statusPublished - jan. 1989

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

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