1. Introduction: The contribution of pathology to radiosurgery

G. Szeifert, D. Kondziolka, L. Lunsford, I. Nyáry, Z. Hanzély, I. Salmon, M. Levivier

Research output: Chapter

5 Citations (Scopus)


The term radiosurgery signifies any kind of application of ionizing radiation energy, in experimental biology or clinical medicine, aiming at the precise and complete destruction of chosen target structures containing healthy and/or pathological cells, without significant concomitant or late radiation damage to adjacent tissues. The goal of this study is to explore the short- and long-term pathophysiological effects of high-dose focused irradiation on neural tissue and its pathologies with histological, electron-microscopical tissue culture and biological-biochemical methods. Radiosurgical pathology focuses its scope and microscope on tissue, cellular, genetic and molecular changes in the human organism and experimental animals, or in cell lines and other in vitro experiments, generated by the ionizing radiation delivered from radiosurgical devices.

Original languageEnglish
Title of host publicationRadiosurgery and Pathological Fundamentals
EditorsGyorgy Szeifert, Marc Levivier, Douglas Kondziolka, Dade Lunsford
Number of pages15
Publication statusPublished - dec. 1 2007

Publication series

NameProgress in Neurological Surgery
ISSN (Print)0079-6492
ISSN (Electronic)1662-3924

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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    Szeifert, G., Kondziolka, D., Lunsford, L., Nyáry, I., Hanzély, Z., Salmon, I., & Levivier, M. (2007). 1. Introduction: The contribution of pathology to radiosurgery. In G. Szeifert, M. Levivier, D. Kondziolka, & D. Lunsford (Eds.), Radiosurgery and Pathological Fundamentals (pp. 1-15). (Progress in Neurological Surgery; Vol. 20). https://doi.org/10.1159/000100090