• 950 Citations
  • 20 h-Index
1989 …2019
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Research Output 1989 2019

  • 950 Citations
  • 20 h-Index
  • 50 Article
  • 2 Short survey
  • 1 Conference contribution
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Article
2019

Drugging the R-loop interactome: RNA-DNA hybrid binding proteins as targets for cancer therapy

Boros-Oláh, B., Dobos, N., Hornyák, L., Szabó, Z., Karányi, Z., Halmos, G., Roszik, J. & Székvölgyi, L., jan. 1 2019, In : DNA Repair. 102642.

Research output: Article

Open Access
DNA-Binding Proteins
Carrier Proteins
RNA
DNA
Neoplasms

Lithocholic acid, a metabolite of the microbiome, increases oxidative stress in breast cancer

Kovács, P., Csonka, T., Kovács, T., Sári, Z., Ujlaki, G., Sipos, A., Karányi, Z., Szeőcs, D., Hegedűs, C., Uray, K., Jankó, L., Kiss, M., Kiss, B., Laoui, D., Virág, L., Méhes, G., Bai, P. & Mikó, E., szept. 1 2019, In : Cancers. 11, 9, 1255.

Research output: Article

Open Access
Lithocholic Acid
Microbiota
Oxidative Stress
Breast Neoplasms
Cytostatic Agents

Screening for preeclampsia in the first trimester of pregnancy in routine clinical practice in Hungary

Orosz, L., Orosz, G., Veress, L., Dosa, D., Orosz, L., Arany, I., Fabian, A., Medve, L., Pap, K., Karányi, Z., Toth, Z., Poka, R., Than, N. G. & Torok, O., júl. 20 2019, In : Journal of Biotechnology. 300, p. 11-19 9 p.

Research output: Article

Hungary
First Pregnancy Trimester
Pre-Eclampsia
Screening
Staphylococcal Protein A
2018
2 Citations (Scopus)
Gene Duplication
Aspergillus
Heat-Shock Proteins
stress tolerance
Fungi
1 Citation (Scopus)
Hyperlipoproteinemia Type II
Data Mining
Hungary
Lipids
Medical Records
2 Citations (Scopus)

Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation

Karányi, Z., Halász, L., Acquaviva, L., Jónás, D., Hetey, S., Boros-Oláh, B., Peng, F., Chen, D., Klein, F., Géli, V. & Székvölgyi, L., okt. 1 2018, In : The Journal of cell biology. 217, 10, p. 3398-3415 18 p.

Research output: Article

Genetic Recombination
Chromatin
DNA Breaks
Meiosis
Histones
2017
12 Citations (Scopus)
Adipokines
Hemostatics
Blood Platelets
P-Selectin
Adiponectin
5 Citations (Scopus)

Biophysical characterization of histone H3.3 K27M point mutation

Hetey, S., Boros-Oláh, B., Kuik-Rózsa, T., Li, Q., Karányi, Z., Szabó, Z., Roszik, J., Szalóki, N., Vámosi, G., Tóth, K. & Székvölgyi, L., aug. 26 2017, In : Biochemical and Biophysical Research Communications. 490, 3, p. 868-875 8 p.

Research output: Article

Nucleosomes
Point Mutation
Histones
Transcription
Methionine
20 Citations (Scopus)

RNA-DNA hybrid (R-loop) immunoprecipitation mapping: An analytical workflow to evaluate inherent biases

Halász, L., Karányi, Z., Boros-Oláh, B., Kuik-Rózsa, T., Sipos, É., Nagy, É., Mosolygó-L, Á., Mázló, A., Rajnavolgyi, E., Halmos, G. & Székvölgyi, L., jún. 1 2017, In : Genome Research. 27, 6, p. 1063-1073 11 p.

Research output: Article

Workflow
Immunoprecipitation
RNA
DNA
Genome
2016
1 Citation (Scopus)
Imagination
Anesthesia
Control Groups
Holidays
Incidence
9 Citations (Scopus)
Macrophage Activation
Bacterial Infections
Fibrosis
Outpatients
Mortality
2014
11 Citations (Scopus)

Rapid response to and long-term effectiveness of anti-CD20 antibody in conventional therapy resistant Graves' orbitopathy: A five-year follow-up study

Erdei, A., Paragh, G., Kovacs, P., Karányi, Z., Berenyi, E., Galuska, L., Lenkey, A., Szabados, L., Gyory, F., Ujhelyi, B., Berta, A., Boda, J., Berta, E., Bodor, M., Gazdag, A. & Nagy, E., dec. 1 2014, In : Autoimmunity. 47, 8, p. 548-555 8 p.

Research output: Article

Glucocorticoids
Anti-Idiotypic Antibodies
Body Surface Area
Single-Photon Emission-Computed Tomography
Magnetic Resonance Imaging
2013
17 Citations (Scopus)
stress response
Fungi
Databases
Heat-Shock Proteins
fungi
42 Citations (Scopus)

Transcriptome changes initiated by carbon starvation in Aspergillus nidulans

Szilágyi, M., Miskei, M., Karányi, Z., Lenkey, B., Pócsi, I. & Emri, T., jan. 2013, In : Microbiology. 159, 1, p. 176-190 15 p.

Research output: Article

Aspergillus nidulans
Starvation
Transcriptome
Carbon
Fungi
2011
28 Citations (Scopus)

Comparison of transcriptional and translational changes caused by long-term menadione exposure in Aspergillus nidulans

Pusztahelyi, T., Klement, E., Szajli, E., Klem, J., Miskei, M., Karányi, Z., Emri, T., Kovács, S., Orosz, G., Kovács, K., Medzihradszky, K. F., Prade, R. A. & Pócsi, I., febr. 2011, In : Fungal Genetics and Biology. 48, 2, p. 92-103 12 p.

Research output: Article

Vitamin K 3
Aspergillus nidulans
Proteome
Oxidative Stress
Nitroreductases
37 Citations (Scopus)
P-Selectin
Platelet Activation
Blood Platelets
Morbidity
Dyslipidemias
6 Citations (Scopus)

Molecular evolution of phosphoprotein phosphatases in Drosophila

Miskei, M., Ádám, C., Kovács, L., Karányi, Z. & Dombrádi, V., 2011, In : PLoS One. 6, 7, e22218.

Research output: Article

phosphoprotein phosphatase
Molecular Evolution
Phosphoprotein Phosphatases
Drosophila
Genes
2010
1 Citation (Scopus)
Cardiac Resynchronization Therapy
Body Mass Index
Heart Failure
Obesity
Stroke Volume
2009
49 Citations (Scopus)
Aspergillus
Heat-Shock Proteins
Schizosaccharomyces
Neosartorya
Fungi
7 Citations (Scopus)

Retrobulbar 99mTc-diethylenetriamine-pentaacetic-acid uptake may predict the effectiveness of immunosuppressive therapy in graves' ophthalmopathy

Ujhelyi, B., Erdei, A., Galuska, L., Varga, J., Szabados, L., Balazs, E., Bodor, M., Cseke, B., Karányi, Z., Leovey, A., Mezősi, E., Burman, K. D., Berta, A. & Nagy, E., ápr. 1 2009, In : Thyroid. 19, 4, p. 375-380 6 p.

Research output: Article

Graves Ophthalmopathy
Pentetic Acid
Immunosuppressive Agents
Orbit
Adrenal Cortex Hormones
68 Citations (Scopus)

The 2008 update of the Aspergillus nidulans genome annotation: a community effort.

Wortman, J. R., Gilsenan, J. M., Joardar, V., Deegan, J., Clutterbuck, J., Andersen, M. R., Archer, D., Bencina, M., Braus, G., Coutinho, P., von Döhren, H., Doonan, J., Driessen, A. J. M., Durek, P., Espeso, E., Fekete, E., Flipphi, M., Estrada, C. G., Geysens, S., Goldman, G. & 66 others, de Groot, P. W. J., Hansen, K., Harris, S. D., Heinekamp, T., Helmstaedt, K., Henrissat, B., Hofmann, G., Homan, T., Horio, T., Horiuchi, H., James, S., Jones, M., Karaffa, L., Karányi, Z., Kato, M., Keller, N., Kelly, D. E., Kiel, J. A. K. W., Kim, J. M., van der Klei, I. J., Klis, F. M., Kovalchuk, A., Krasevec, N., Kubicek, C. P., Liu, B., Maccabe, A., Meyer, V., Mirabito, P., Miskei, M., Mos, M., Mullins, J., Nelson, D. R., Nielsen, J., Oakley, B. R., Osmani, S. A., Pakula, T., Paszewski, A., Paulsen, I., Pilsyk, S., Pócsi, I., Punt, P. J., Ram, A. F. J., Ren, Q., Robellet, X., Robson, G., Seiboth, B., van Solingen, P., Specht, T., Sun, J., Taheri-Talesh, N., Takeshita, N., Ussery, D., vanKuyk, P. A., Visser, H., van de Vondervoort, P. J. I., de Vries, R. P., Walton, J., Xiang, X., Xiong, Y., Zeng, A. P., Brandt, B. W., Cornell, M. J., van den Hondel, C. A. M. J. J., Visser, J., Oliver, S. G. & Turner, G., márc. 2009, In : Fungal Genetics and Biology. 46 Suppl 1

Research output: Article

Aspergillus nidulans
Genome
Molecular Sequence Annotation
Proteins
Databases
2008
20 Citations (Scopus)
Rheumatoid Factor
HLA-DRB1 Chains
Antibodies
Anti-Idiotypic Antibodies
Rheumatoid Arthritis
12 Citations (Scopus)

Physiological and morphological characterization of tert-butylhydroperoxide tolerant Candida albicans mutants

Fekete, A., Pócsi, I., Emri, T., Gyetvai, Á., Gazdag, Z., Pesti, M., Karányi, Z., Majoros, L., Gergely, L. & Pócsi, I., dec. 2008, In : Journal of Basic Microbiology. 48, 6, p. 480-487 8 p.

Research output: Article

tert-Butylhydroperoxide
Candida albicans
Oxidative Stress
Respiration
Flucytosine
25 Citations (Scopus)

Relationship of adiponectin to serum paraoxonase 1

Bajnok, L., Csongradi, E., Seres, I., Varga, Z., Jeges, S., Peti, A., Karányi, Z., Juhász, A., Mezősi, E., Nagy, E. & Paragh, G., márc. 2008, In : Atherosclerosis. 197, 1, p. 363-367 5 p.

Research output: Article

Aryldialkylphosphatase
Adiponectin
Serum
Insulin
Waist Circumference
21 Citations (Scopus)
Resistin
Aryldialkylphosphatase
Body Mass Index
Obesity
Antioxidants
2007
4 Citations (Scopus)

Effect of heavy metals on the glutathione status in different ectomycorrhizal Paxillus involutus strains

Hegedus, N., Emri, T., Szilágyi, J., Karányi, Z., Nagy, I., Penninckx, M. J. & Pócsi, I., szept. 2007, In : World Journal of Microbiology and Biotechnology. 23, 9, p. 1339-1343 5 p.

Research output: Article

Paxillus involutus
Heavy Metals
Glutathione
glutathione
heavy metals
28 Citations (Scopus)
Cholesterol Ester Transfer Proteins
Phosphatidylcholine-Sterol O-Acyltransferase
Aryldialkylphosphatase
Leptin
Insulin Resistance
2006
7 Citations (Scopus)
Multicenter Studies
Clinical Trials
Safety
Quality of Life
Depression
8 Citations (Scopus)
Aryldialkylphosphatase
Leptin
Renal Dialysis
Body Mass Index
Triglycerides
2005
3 Citations (Scopus)
Depression
Therapeutics
Creativity
Comorbidity
Demography
59 Citations (Scopus)
Diamide
Vitamin K 3
Aspergillus nidulans
Glutathione Disulfide
Transcriptome
23 Citations (Scopus)

Different anticancer effects of fluvastatin on primary hepatocellular tumors and metastases in rats

Paragh, G., Fóris, G., Paragh, G., Seres, I., Karányi, Z., Fülöp, P., Balogh, Z., Kosztáczky, B., Teichmann, F. & Kertai, P., máj. 10 2005, In : Cancer Letters. 222, 1, p. 17-22 6 p.

Research output: Article

fluvastatin
Pyruvate Kinase
Neoplasm Metastasis
Neoplasms
Growth
17 Citations (Scopus)
Hyperlipidemias
Myocardial Ischemia
Electrocardiography
Apolipoproteins B
LDL Cholesterol
2002
3 Citations (Scopus)

Akut toxikológiai eseteink klinikánk tízéves beteganyagában.

Kovács, T., Páll, D., Abafalvi, Z., Karányi, Z., Wórum, F., Mátyus, J., Kárpáti, I., Balla, J., Ujhelyi, L. & Kakuk, G., jan. 13 2002, In : Orvosi Hetilap. 143, 2, p. 71-76 6 p.

Research output: Article

Toxicology
Poisoning
Suicide
Psychiatry
Glutethimide
42 Citations (Scopus)

Effects of haemodialysis on maximum P wave duration and P wave dispersion

Szabó, Z., Kakuk, G., Fülöp, T., Mátyus, J., Balla, J., Kárpáti, I., Juhász, A., Kun, C., Karányi, Z. & Lorincz, I., szept. 2002, In : Nephrology Dialysis Transplantation. 17, 9, p. 1634-1638 5 p.

Research output: Article

Renal Dialysis
Dialysis
Dialysis Solutions
Bicarbonates
Chronic Kidney Failure
36 Citations (Scopus)

Using morphologic parameters of extraocular muscles for diagnosis and follow-up of graves' ophthalmopathy: Diameters, areas, or volumes?

Szucs-Farkas, Z., Toth, J., Balazs, E., Galuska, L., Burman, K. D., Karányi, Z., Leovey, A. & Nagy, E., okt. 2002, In : American Journal of Roentgenology. 179, 4, p. 1005-1010 6 p.

Research output: Article

Oculomotor Muscles
Graves Ophthalmopathy
Muscles
Orbit
2001
38 Citations (Scopus)
allosamidin
Penicillium chrysogenum
Autolysis
Chitinases
Starvation
2000
57 Citations (Scopus)

Graves' ophthalmopathy: Eye muscle involvement in patients with diplopia

Nagy, E., Toth, J., Kaldi, I., Damjanovich, J., Mezősi, E., Lenkey, A., Toth, L., Szabo, J., Karányi, Z. & Leovey, A., jún. 2000, In : European Journal of Endocrinology. 142, 6, p. 591-597 7 p.

Research output: Article

Graves Ophthalmopathy
Diplopia
Muscles
Connective Tissue
Magnetic Resonance Imaging
2 Citations (Scopus)

Prevalence of cardiovascular risk factors of the smokers and non-smokers in the city of Debrecen, Hungary

Jenei, Z., Páll, D., Katona, E., Polgár, P., Karányi, Z., Bodor, M. & Kakuk, G., 2000, In : Public Health. 114, 4, p. 295-299 5 p.

Research output: Article

Hungary
Disease
Cardiovascular Diseases
heart attack
questionnaire
23 Citations (Scopus)

Prevalence of iodine deficiency and goitre during pregnancy in east Hungary

Mezősi, E., Molnar, I., Jakab, A., Balogh, E., Karányi, Z., Pakozdy, Z., Nagy, P., Gyory, F., Szabo, J., Bajnok, L., Leovey, A., Kakuk, G. & Nagy, E., 2000, In : European Journal of Endocrinology. 143, 4, p. 479-483 5 p.

Research output: Article

Hungary
Goiter
Iodine
Pregnancy
Pregnant Women
1999
1 Citation (Scopus)

A hemodialízis hatása a QT diszperzióra krónikus uraemiás betegekben.

Lörincz, I., Mátyus, J., Zilahi, Z., Kun, C., Karányi, Z. & Kakuk, G., jan. 3 1999, In : Orvosi Hetilap. 140, 1, p. 15-19 5 p.

Research output: Article

Uremia
Renal Dialysis
Electrocardiography
Cardiac Arrhythmias
Heart Diseases

A pitvari fibrilláció megelözése pitvari vagy pitvar-kamrai szekvenciális pacemaker-beültetéssel.

Lörincz, I., Vaszily, M., Szabó, Z., Horváth, G., Kovács, P., Polgár, P., Karányi, Z. & Wórum, F., okt. 24 1999, In : Orvosi Hetilap. 140, 43, p. 2393-2397 5 p.

Research output: Article

Atrial Fibrillation
Sick Sinus Syndrome
Propafenone
Atrioventricular Node
Sinoatrial Node
98 Citations (Scopus)

QT dispersion in patients with end-stage renal failure and during hemodialysis

Lorincz, I., Mátyus, J., Zilahi, Z., Kun, C., Karányi, Z. & Kakuk, G., jún. 1999, In : Journal of the American Society of Nephrology. 10, 6, p. 1297-1302 6 p.

Research output: Article

Chronic Kidney Failure
Renal Dialysis
Electrocardiography
Dialysis Solutions
Bicarbonates
4 Citations (Scopus)
Streptokinase
Myocardial Infarction
Thrombolytic Therapy
Tachycardia
Electrocardiography
1998
40 Citations (Scopus)
allosamidin
Acremonium
Chitinases
Fungi
Chitin
1996
1 Citation (Scopus)
Ambulatory Blood Pressure Monitoring
Blood Pressure
Patient Compliance
Hypertension
benazepril
13 Citations (Scopus)

Changes in superoxide anion production and phagocytosis by circulating neutrophils during tumor progression in a rat model

Szucs, S., Kávai, M., Varga, C., Kertai, P., Pocsai, Z., Karányi, Z. & Ádány, R., jún. 15 1996, In : Cellular Immunology. 170, 2, p. 202-211 10 p.

Research output: Article

Phagocytosis
Superoxides
Neutrophils
Neoplasms
Mesoblastic Nephroma
2 Citations (Scopus)

Mozgásszervi betegségek helyi kezelése propolisz készítményekkel.

Síró, B., Szelekovszky, S., Lakatos, B., Mády, G., Szathmári, E. & Karányi, Z., jún. 23 1996, In : Orvosi Hetilap. 137, 25, p. 1365-1370 6 p.

Research output: Article

Propolis
Trace Elements
Rheumatic Diseases
Metals
Iontophoresis
1995

Captopril kezelés felváltása cilazapril terápiával enyhe és középsúlyos essentialis hypertoniában.

Kovács, P., Juhász, A., Gábeli, T., Karányi, Z., Polgár, P., Paragh, G., Lörincz, I. & Arnold, C., okt. 15 1995, In : Orvosi Hetilap. 136, 42, p. 2273-2278 6 p.

Research output: Article

Cilazapril
Captopril
Compliance
Therapeutics
Blood Pressure
1989
1 Citation (Scopus)
Thyroid-Stimulating Immunoglobulins
Methimazole
Graves Disease
Thyrotropin
Immunoglobulins