• 4292 Citations
  • 37 h-Index
19962020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Capsaicin-sensitive sensory nerves and the trpv1 ion channel in cardiac physiology and pathologies

Szabados, T., Gömöri, K., Pálvölgyi, L., Görbe, A., Baczkó, I., Helyes, Z., Jancsó, G., Ferdinandy, P. & Bencsik, P., jún. 23 2020, In : International journal of molecular sciences. 21, 12, p. 1-23 23 p., 4472.

Research output: Review article

Open Access

Complex regulatory role of the trpa1 receptor in acute and chronic airway inflammation mouse models

Hajna, Z., Csekő, K., Kemény, Á., Kereskai, L., Kiss, T., Perkecz, A., Szitter, I., Kocsis, B., Pintér, E. & Helyes, Z., jún. 1 2020, In : International journal of molecular sciences. 21, 11, p. 1-21 21 p., 4109.

Research output: Article

Open Access
1 Citation (Scopus)
Open Access

Repositioning PARP inhibitors for SARS-CoV-2 infection (COVID-19); a new multi-pronged therapy for ARDS?

Curtin, N., Bányai, K., Thaventhiran, J., Le Quesne, J., Helyes, Z. & Bai, P., 2020, (Accepted/In press) In : British journal of pharmacology.

Research output: Review article

Open Access
1 Citation (Scopus)
2019
Open Access

Exploratory and locomotor activity, learning and memory functions in somatostatin receptor subtype 4 gene-deficient mice in relation to aging and sex

Szentes, N., Tékus, V., Mohos, V., Borbély, É. & Helyes, Z., okt. 1 2019, In : GeroScience. 41, 5, p. 631-641 11 p.

Research output: Article

Open Access
2 Citations (Scopus)

Expression and activity of TRPA1 and TRPV1 in the intervertebral disc: Association with inflammation and matrix remodeling

Kameda, T., Zvick, J., Vuk, M., Sadowska, A., Tam, W. K., Leung, V. Y., Bölcskei, K., Helyes, Z., Applegate, L. A., Hausmann, O. N., Klasen, J., Krupkova, O. & Wuertz-Kozak, K., ápr. 1 2019, In : International journal of molecular sciences. 20, 7, 1767.

Research output: Article

Open Access
3 Citations (Scopus)

Hemokinin-1 is an important mediator of pain in mouse models of neuropathic and inflammatory mechanisms

Hunyady, Á., Hajna, Z., Gubányi, T., Scheich, B., Kemény, Á., Gaszner, B., Borbély, É. & Helyes, Z., ápr. 2019, In : Brain Research Bulletin. 147, p. 165-173 9 p.

Research output: Article

Open Access
4 Citations (Scopus)

IL-22-independent protection from colitis in the absence of Nkx2.3 transcription factor in mice

Kellermayer, Z., Vojkovics, D., Dakah, T. A., Bodó, K., Botz, B., Helyes, Z., Berta, G., Kajtár, B., Schippers, A., Wagner, N., Scotto, L., O'Connor, O. A., Arnold, H. H. & Balogh, P., jan. 1 2019, In : Journal of Immunology. 202, 6, p. 1833-1844 12 p.

Research output: Article

3 Citations (Scopus)

Mechanisms of botulinum toxin type A action on pain

Matak, I., Bölcskei, K., Bach-Rojecky, L. & Helyes, Z., aug. 2019, In : Toxins. 11, 8, 459.

Research output: Review article

Open Access
11 Citations (Scopus)

Role of TRPV1 and TRPA1 ion channels in inflammatory bowel diseases: Potential therapeutic targets?

Csekő, K., Beckers, B., Keszthelyi, D. & Helyes, Z., jún. 2019, In : Pharmaceuticals. 12, 2, 48.

Research output: Review article

Open Access
5 Citations (Scopus)

Significance of the Tks4 scaffold protein in bone tissue homeostasis

Vas, V., Kovács, T., Körmendi, S., Bródy, A., Kudlik, G., Szeder, B., Mező, D., Kállai, D., Koprivanacz, K., Merő, B. L., Dülk, M., Tóvári, J., Vajdovich, P., Şenel, N., Özcan, I., Helyes, Z., Dobó-Nagy, C. & Buday, L., dec. 1 2019, In : Scientific reports. 9, 1, 5781.

Research output: Article

Open Access

Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1–induced mechanisms

Helyes, Z., Tékus, V., Szentes, N., Pohóczky, K., Botz, B., Kiss, T., Kemény, Á., Környei, Z., Tóth, K., Lénárt, N., Ábrahám, H., Pinteaux, E., Francis, S., Sensi, S., Dénes, Á. & Goebel, A., jan. 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 26, p. 13067-13076 10 p.

Research output: Article

Open Access
7 Citations (Scopus)

TRPA1 ion channel determines beneficial and detrimental effects of GYY4137 in murine serum-transfer arthritis

Bátai, I. Z., Sár, C. P., Horváth, Á., Borbély, É., Bölcskei, K., Kemény, Á., Sándor, Z., Nemes, B., Helyes, Z., Perkecz, A., Mócsai, A., Pozsgai, G. & Pintér, E., 2019, In : Frontiers in Pharmacology. 10, 964.

Research output: Article

Open Access
2018
8 Citations (Scopus)

A transgenic mouse model for detection of tissue-specific thyroid hormone action

Mohácsik, P., Erdélyi, F., Baranyi, M., Botz, B., Szabó, G., Tóth, M., Haltrich, I., Helyes, Z., Sperlágh, B., Tóth, Z., Sinkó, R., Lechan, R. M., Bianco, A. C., Fekete, C. & Gereben, B., febr. 2018, In : Endocrinology. 159, 2, p. 1159-1171 13 p.

Research output: Article

4 Citations (Scopus)

Body fat of rats of different age groups and nutritional states: Assessment by micro-CT and skinfold thickness

Tekus, E., Miko, A., Furedi, N., Rostas, I., Tenk, J., Kiss, T., Szitter, I., Balasko, M., Helyes, Z., Wilhelm, M. & Petervari, E., febr. 2018, In : Journal of Applied Physiology. 124, 2, p. 268-275 8 p.

Research output: Article

1 Citation (Scopus)

Carboxamido steroids inhibit the opening properties of transient receptor potential ion channels by lipid raft modulation

Sághy, É., Payrits, M., Bíró-Sütő, T., Skoda-Földes, R., Szánti-Pintér, E., Erostyák, J., Makkai, G., Sétáló, G., Kollár, L., Kőszegi, T., Csepregi, R., Szolcsányi, J., Helyes, Z. & Szőke, É., jan. 1 2018, In : Journal of Lipid Research. 59, 10, p. 1851-1863 13 p.

Research output: Article

9 Citations (Scopus)
7 Citations (Scopus)
2 Citations (Scopus)

Correlation of neurochemical and imaging markers in migraine: PACAP38 and DTI measures

Veréb, D., Szabó, N., Tuka, B., Tajti, J., Király, A., Faragó, P., Kocsis, K., Tóth, E., Kincses, B., Bagoly, T., Helyes, Z., Vécsei, L. & Kincses, Z. T., szept. 18 2018, In : Neurology. 91, 12, p. e1166-e1174

Research output: Article

4 Citations (Scopus)

Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain

Király, K., Kozsurek, M., Lukácsi, E., Barta, B., Alpár, A., Balázsa, T., Fekete, C., Szabon, J., Helyes, Z., Bölcskei, K., Tékus, V., Tóth, Z. E., Pap, K., Gerber, G. & Puskár, Z., dec. 1 2018, In : Scientific reports. 8, 1, 3490.

Research output: Article

4 Citations (Scopus)
3 Citations (Scopus)
6 Citations (Scopus)

Long-term stress and concomitant marijuana smoke exposure affect physiology, behavior and adult hippocampal neurogenesis

Rusznák, K., Cseko, K., Varga, Z., Csabai, D., Bóna, Á., Mayer, M., Kozma, Z., Helyes, Z. & Czéh, B., júl. 23 2018, In : Frontiers in Pharmacology. 9, JUL, 786.

Research output: Article

4 Citations (Scopus)

Regulatory role of capsaicin-sensitive peptidergic sensory nerves in the proteoglycan-induced autoimmune arthritis model of the mouse

Horváth, Á., Borbély, É., Bölcskei, K., Szentes, N., Kiss, T., Belák, M., Rauch, T., Glant, T., Zákány, R., Juhász, T., Karanyicz, E., Boldizsár, F., Helyes, Z. & Botz, B., dec. 3 2018, In : Journal of Neuroinflammation. 15, 1, 335.

Research output: Article

4 Citations (Scopus)

Selegiline reduces adiposity induced by high-fat, high-sucrose diet in male rats

Nagy, C. T., Koncsos, G., Varga, Z. V., Baranyai, T., Tuza, S., Kassai, F., Ernyey, A. J., Gyertyán, I., Király, K., Oláh, A., Radovits, T., Merkely, B., Bukosza, N., Szénási, G., Hamar, P., Mathé, D., Szigeti, K., Pelyhe, C., Jelemenský, M., Onódi, Z. & 4 others, Helyes, Z., Schulz, R., Giricz, Z. & Ferdinandy, P., szept. 2018, In : British journal of pharmacology. 175, 18, p. 3713-3726 14 p.

Research output: Article

5 Citations (Scopus)

Signalling alterations in bones of pituitary adenylate cyclase activating polypeptide (PACAP) gene deficient mice

Józsa, G., Szegeczki, V., Pálfi, A., Kiss, T., Helyes, Z., Fülöp, B., Cserháti, C., Daróczi, L., Tamás, A., Zákány, R., Reglődi, D. & Juhász, T., szept. 2018, In : International journal of molecular sciences. 19, 9, 2538.

Research output: Article

3 Citations (Scopus)
6 Citations (Scopus)

Traumatic brain injury impairs myogenic constriction of cerebral arteries: Role of mitochondria-derived H 2 O 2 and TRPV4-Dependent Activation of BK ca Channels

Szarka, N., Pabbidi, M. R., Amrein, K., Czeiter, E., Berta, G., Pohoczky, K., Helyes, Z., Ungvari, Z., Koller, A., Buki, A. & Toth, P., ápr. 1 2018, In : Journal of Neurotrauma. 35, 7, p. 930-939 10 p.

Research output: Article

16 Citations (Scopus)
2017

Analysing the effect of I1 imidazoline receptor ligands on DSS-induced acute colitis in mice

Fehér, Á., Tóth, V. E., Al-Khrasani, M., Balogh, M., Lázár, B., Helyes, Z., Gyires, K. & Zádori, Z. S., febr. 1 2017, In : InflammoPharmacology. 25, 1, p. 107-118 12 p.

Research output: Article

2 Citations (Scopus)
13 Citations (Scopus)

Contribution of platelet P2Y12 receptors to chronic Complete Freund's adjuvant-induced inflammatory pain

Bekő, K., Koványi, B., Gölöncsér, F., Horváth, G., Dénes, Környei, Z., Botz, B., Helyes, Z., Müller, C. E. & Sperlágh, B., jún. 2017, In : Journal of Thrombosis and Haemostasis. 15, 6, p. 1223-1235 13 p.

Research output: Article

10 Citations (Scopus)

Estradiol sensitizes the transient receptor potential vanilloid 1 receptor in pain responses

Payrits, M., Sághy, É., Cseko, K., Pohóczky, K., Bölcskei, K., Ernszt, D., Barabás, K., Szolcsányi, J., Ábrahám, I. M., Helyes, Z. & Szöke, E., okt. 1 2017, In : Endocrinology. 158, 10, p. 3249-3258 10 p.

Research output: Article

11 Citations (Scopus)

Exploration of the esophageal mucosal barrier in non-erosive reflux disease

Rinsma, N. F., Farré, R., Troost, F. J., Elizalde, M., Keszthelyi, D., Helyes, Z., Masclee, A. A. & Conchillo, J. M., máj. 19 2017, In : International journal of molecular sciences. 18, 5, 1091.

Research output: Article

6 Citations (Scopus)

Integrative characterization of chronic cigarette smoke-induced cardiopulmonary comorbidities in a mouse model

Kemény, Á., Csekő, K., Szitter, I., Varga, Z. V., Bencsik, P., Kiss, K., Halmosi, R., Deres, L., Erős, K., Perkecz, A., Kereskai, L., László, T., Kiss, T., Ferdinándy, P. & Helyes, Z., jan. 1 2017, In : Environmental Pollution. 229, p. 746-759 14 p.

Research output: Article

6 Citations (Scopus)

Involvement of substance P in the antinociceptive effect of botulinum toxin type A: Evidence from knockout mice

Matak, I., Tékus, V., Bölcskei, K., Lacković, Z. & Helyes, Z., szept. 1 2017, In : Neuroscience. 358, p. 137-145 9 p.

Research output: Article

12 Citations (Scopus)

Local upregulation of transient receptor potential ankyrin I and transient receptor potential vanilloid I ion channels in rectosigmoid deep infiltrating endometriosis

Bohonyi, N., Pohóczky, K., Szalontai, B., Perkecz, A., Kovács, K., Kajtár, B., Orbán, L., Varga, T., Szegedi, S., Bódis, J., Helyes, Z. & Koppán, M., jan. 1 2017, In : Molecular Pain. 13

Research output: Article

5 Citations (Scopus)
9 Citations (Scopus)

Review article: transient receptor potential channels as possible therapeutic targets in irritable bowel syndrome

Beckers, A. B., Weerts, Z. Z. R. M., Helyes, Z., Masclee, A. A. M. & Keszthelyi, D., nov. 2017, In : Alimentary Pharmacology and Therapeutics. 46, 10, p. 938-952 15 p.

Research output: Review article

13 Citations (Scopus)
1 Citation (Scopus)
2016

Activity of botulinum toxin type A in cranial dura: Implications for treatment of migraine and other headaches

Lackovic, Z., Filipovic, B., Matak, I. & Helyes, Z., jan. 1 2016, In : British journal of pharmacology. 173, 2, p. 279-291 13 p.

Research output: Article

27 Citations (Scopus)

A novel 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanal oxime compound is a potent Transient Receptor Potential Ankyrin 1 and Vanilloid 1 (TRPA1 and V1) receptor antagonist

Payrits, M., Sághy, Mátyus, P., Czompa, A., Ludmerczki, R., Deme, R., Sándor, Z., Helyes, Z. & Szoke, jún. 2 2016, In : Neuroscience. 324, p. 151-162 12 p.

Research output: Article

12 Citations (Scopus)

Capsaicin-induced satiety is associated with gastrointestinal distress but not with the release of satiety hormones

Van Avesaat, M., Troost, F. J., Westerterp-Plantenga, M. S., Helyes, Z., Le Roux, C. W., Dekker, J., Masclee, A. A. M. & Keszthelyi, D., febr. 1 2016, In : American Journal of Clinical Nutrition. 103, 2, p. 305-313 9 p.

Research output: Article

16 Citations (Scopus)

Capsaicin-Sensitive Sensory Nerves Mediate the Cellular and Microvascular Effects of H2S via TRPA1 Receptor Activation and Neuropeptide Release

Hajna, Z., Sághy, É., Payrits, M., Aubdool, A. A., Szőke, É., Pozsgai, G., Bátai, I. Z., Nagy, L., Filotás, D., Helyes, Z., Brain, S. D. & Pintér, E., okt. 1 2016, In : Journal of Molecular Neuroscience. 60, 2, p. 157-170 14 p.

Research output: Article

14 Citations (Scopus)

Estrogen-dependent up-regulation of TRPA1 and TRPV1 receptor proteins in the rat endometrium

Pohóczky, K., Kun, J., Szalontai, B., Szöke, É., Sághy, É., Payrits, M., Kajtár, B., Kovács, K., Környei, J. L., Garai, J., Garami, A., Perkecz, A., Czeglédi, L. & Helyes, Z., febr. 1 2016, In : Journal of Molecular Endocrinology. 56, 2, p. 135-149 15 p.

Research output: Article

17 Citations (Scopus)

Galanin 3 receptor-deficient mice show no alteration in the oxazolone-induced contact dermatitis phenotype

Botz, B., Brunner, S. M., Kemény, Á., Pintér, E., McDougall, J. J., Kofler, B. & Helyes, Z., szept. 1 2016, In : Experimental Dermatology. 25, 9, p. 725-727 3 p.

Research output: Letter

2 Citations (Scopus)
2 Citations (Scopus)