• 1046 Citations
  • 19 h-Index
19962019
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Research Output 1996 2019

  • 1046 Citations
  • 19 h-Index
  • 51 Article
  • 2 Review article
2019
3 Citations (Scopus)
Azirines
Isatin
Cycloaddition
Imidazolidines
Amino Acids
1 Citation (Scopus)

Achieving functionality through modular build-up: Structure and size selection of serine oligopeptidases

Kiss-Szemán, A. J., Harmat, V. & Menyhárd, D. K., jan. 1 2019, In : Current Protein and Peptide Science. 20, 11, p. 1089-1101 13 p.

Research output: Review article

Serine
Serine Proteases
prolyl oligopeptidase
Substrates
Oligopeptides
1 Citation (Scopus)

Radiation-damage investigation of a DNA 16-mer

Bugris, V., Harmat, V., Ferenc, G., Brockhauser, S., Carmichael, I. & Garman, E. F., júl. 1 2019, In : Journal of Synchrotron Radiation. 26, p. 998-1009 12 p.

Research output: Article

Radiation damage
radiation damage
DNA
deoxyribonucleic acid
proteins
1 Citation (Scopus)

Structural diversity in calmodulin-peptide interactions

Dürvanger, Z. & Harmat, V., jan. 1 2019, In : Current Protein and Peptide Science. 20, 11, p. 1102-1111 10 p.

Research output: Review article

Calmodulin
Peptides
Consensus Sequence
Cells
Sensors
2018
2 Citations (Scopus)
sugars
Sugars
amino acids
Amino Acids
synthesis
1 Citation (Scopus)
Calcium Gluconate
waste disposal
Waste disposal
calcium
Calcium
3 Citations (Scopus)
x ray analysis
cultured cells
Theoretical Models
Cells
X-Rays
2017
Molecular Structure
Molecular structure
Urea
Phthalimides
Imides
2016
5 Citations (Scopus)

Origin of problems related to Staudinger reduction in carbopeptoid syntheses

Csordás, B., Nagy, A., Harmat, V., Zsoldos-Mády, V., Leveles, I., Pintér, I., Farkas, V. & Perczel, A., júl. 20 2016, (Accepted/In press) In : Amino Acids. p. 1-15 15 p.

Research output: Article

Peptides
Derivatives
Amino Acids
Sugar Acids
Rubiaceae
2015
4 Citations (Scopus)
Enzymes
Aeropyrum
Peptides
Molecular Dynamics Simulation
Catalytic Domain
2013
11 Citations (Scopus)

A self-compartmentalizing hexamer serine protease from Pyrococcus Horikoshii: Substrate selection achieved through multimerization

Menyhárd, D. K., Kiss-Szemán, A., Tichy-Rács, É., Hornung, B., Rádi, K., Szeltner, Z., Domokos, K., Szamosi, I., Náray-Szabó, G., Polgár, L. & Harmat, V., jún. 14 2013, In : Journal of Biological Chemistry. 288, 24, p. 17884-17894 11 p.

Research output: Article

Pyrococcus horikoshii
Serine Proteases
Substrates
Monomers
Self assembly
43 Citations (Scopus)
Mannose-Binding Protein-Associated Serine Proteases
Mannose-Binding Lectin Complement Pathway
Mannose-Binding Lectin
Serine Proteases
Lectins
18 Citations (Scopus)

Structure and enzymatic mechanism of a moonlighting dUTPase

Leveles, I., Németh, V., Szabó, J. E., Harmat, V., Nyíri, K., Bendes, Á. Á., Papp-Kádár, V., Zagyva, I., Róna, G., Ozohanics, O., Vékey, K., Tóth, J. & Vértessy, B., dec. 2013, In : Acta Crystallographica Section D: Biological Crystallography. 69, 12, p. 2298-2308 11 p.

Research output: Article

Bacteriophages
Staphylococcus Phages
Ions
Genomic Islands
Staphylococcus
2011
4 Citations (Scopus)
Bacteriophages
staphylococcus
Crystallization
Genomic Islands
Staphylococcus aureus
38 Citations (Scopus)
Bacteriophages
dimerization
Dimerization
Proteome
proteome
30 Citations (Scopus)

Structure and catalysis of acylaminoacyl peptidase: Closed and open subunits of a dimer oligopeptidase

Harmat, V., Domokos, K., Menyhárd, D. K., Palló, A., Szeltner, Z., Szamosi, I., Beke-Somfai, T., Náray-Szabó, G. & Polgár, L., jan. 21 2011, In : Journal of Biological Chemistry. 286, 3, p. 1987-1998 12 p.

Research output: Article

Catalysis
Dimers
Substrates
Enzymes
prolyl oligopeptidase
2010
38 Citations (Scopus)
Esters
Hydrolysis
Nucleotides
Phosphates
Catalysis
12 Citations (Scopus)
Catalytic Domain
Enzymes
Viperidae
Genes
Genome
4 Citations (Scopus)
Sphingolipids
Calmodulin
Lipids
Proteins
Calcium Signaling
2009
9 Citations (Scopus)
Endopeptidases
Static Electricity
prolyl oligopeptidase
Electrostatics
Pyrococcus horikoshii
79 Citations (Scopus)
Mannose-Binding Protein-Associated Serine Proteases
Catalytic Domain
Peptide Hydrolases
Serine Proteases
Mannose-Binding Lectin Complement Pathway
2008
17 Citations (Scopus)

Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules

Kánai, K., Arányi, P., Böcskei, Z., Ferenczy, G., Harmat, V., Simon, K., Bátori, S., Náray-Szabó, G. & Hermecz, I., dec. 11 2008, In : Journal of Medicinal Chemistry. 51, 23, p. 7514-7522 9 p.

Research output: Article

prolyl oligopeptidase
Fluorine
Enzymes
Molecular Dynamics Simulation
Proline
16 Citations (Scopus)
Mannose-Binding Lectin
protease
X ray analysis
Serine Proteases
Crystallization
28 Citations (Scopus)
Complement C1r
Serine Proteases
Catalytic Domain
Peptide Hydrolases
Classical Complement Pathway
12 Citations (Scopus)
Binding Sites
Aeropyrum
Enzymes
Entropy
Serine Proteases
2007
72 Citations (Scopus)
Hereditary Angioedemas
Serpins
Antithrombin III
Heparin
Conformations
35 Citations (Scopus)

Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins

Németh-Pongrácz, V., Barabás, O., Fuxreiter, M., Simon, I., Pichová, I., Rumlová, M., Zábranská, H., Svergun, D., Petoukhov, M., Harmat, V., Klement, E., Hunyadi-Gulyás, E., Medzihradszky, K. F., Kónya, E. & Vértessy, B., jan. 2007, In : Nucleic Acids Research. 35, 2, p. 495-505 11 p.

Research output: Article

Nucleocapsid Proteins
Nucleocapsid
Betaretrovirus
X-Rays
RNA Folding
29 Citations (Scopus)

The Acylaminoacyl Peptidase from Aeropyrum pernix K1 Thought to Be an Exopeptidase Displays Endopeptidase Activity

Kiss, A. L., Hornung, B., Rádi, K., Gengeliczki, Z., Sztáray, B., Juhász, T., Szeltner, Z., Harmat, V. & Polgár, L., ápr. 27 2007, In : Journal of Molecular Biology. 368, 2, p. 509-520 12 p.

Research output: Article

Aeropyrum
Exopeptidases
Endopeptidases
Oligopeptides
Peptides
2006
29 Citations (Scopus)

Enzyme: substrate hydrogen bond shortening during the acylation phase of serine protease catalysis

Fodor, K., Harmat, V., Neutze, R., Szilágyi, L., Gráf, L. & Katona, G., febr. 21 2006, In : Biochemistry. 45, 7, p. 2114-2121 8 p.

Research output: Article

Acylation
Serine Proteases
Catalysis
Hydrogen
Hydrogen bonds
2005
83 Citations (Scopus)

A true autoactivating enzyme: Structural insight into mannose-binding lectin-associated serine protease-2 activations

Gál, P., Harmat, V., Kocsis, A., Bián, T., Barna, L., Ambrus, G., Végh, B., Balczer, J., Sim, R. B., Náray-Szabó, G. & Závodszky, P., szept. 30 2005, In : Journal of Biological Chemistry. 280, 39, p. 33435-33444 10 p.

Research output: Article

Mannose-Binding Lectin
Serine Proteases
Enzyme Precursors
Chemical activation
Enzymes
41 Citations (Scopus)
Serine Proteinase Inhibitors
Trypsin
Astacoidea
Trypsin Inhibitors
Arthropods
19 Citations (Scopus)

Structural evidence for non-canonical binding of Ca 2+ to a canonical EF-hand of a conventional myosin

Debreczeni, J. É., Farkas, L., Harmat, V., Hetényi, C., Hajdú, I., Závodszky, P., Kohama, K. & Nyitray, L., dec. 16 2005, In : Journal of Biological Chemistry. 280, 50, p. 41458-41464 7 p.

Research output: Article

Myosin Type II
EF Hand Motifs
Physarum
Myosins
Deuterium
11 Citations (Scopus)
1-Octanol
solvolysis
Silicon
Molecular Structure
ureas
19 Citations (Scopus)
Calmodulin
Pharmacology
Pharmaceutical Preparations
Trifluoperazine
Diffraction
2004
1 Citation (Scopus)
cyclopropane
Molecular modeling
Lactones
Molecular Structure
X-Ray Diffraction
65 Citations (Scopus)
Mannose-Binding Lectin
Serine Proteases
Substrate Specificity
Enzymes
Mannose-Binding Lectin Complement Pathway
2003
15 Citations (Scopus)

Fragmentation-related phosphinylations using 2-aryl-2-phosphabicyclo[2.2.2]oct-5-ene- and -octa-5,7-diene 2-oxides

Keglevich, G., Szelke, H., Bálint, Á., Imre, T., Ludányi, K., Nagy, Z., Hanusz, M., Simon, K., Harmat, V. & Tőke, L., 2003, In : Heteroatom Chemistry. 14, 5, p. 443-451 9 p.

Research output: Article

phosphine
Oxides
Amines
11 Citations (Scopus)

Lipophilicity of aminopyridazinone regioisomers

Anwair, M. A. S., Károlyházy, L., Szabó, D., Balogh, B., Kövesdi, I., Harmat, V., Krenyácz, J., Gellért, Á., Takács-Novák, K. & Mátyus, P., aug. 27 2003, In : Journal of Agricultural and Food Chemistry. 51, 18, p. 5262-5270 9 p.

Research output: Article

hydrophobicity
Isomers
isomers
Octanols
octanol-water partition coefficients
7 Citations (Scopus)

Novel ortho- and peri-fused pyridazine ring systems

Éliás, O., Károlyházy, L., Horváth, G., Harmat, V. & Mátyus, P., dec. 29 2003, In : Journal of Molecular Structure: THEOCHEM. 666-667, p. 625-636 12 p.

Research output: Article

Cyclization
Substitution reactions
Polycyclic Compounds
rings
Skeleton
2002

Az 1-[(trifluor-metil)fenil]pirrolok regioszelektív metallálási reakciói

Faigl, F., Fogassy, K., Szucs, E., Kovács, K., Tőke, L., Keserü, G. M., Harmat, V. & Böcskei, Z., júl. 2002, In : Magyar Kemiai Folyoirat, Kemiai Kozlemenyek. 108, 7, p. 317-324 8 p.

Research output: Article

Pyrroles
Carboxylation
Molecular modeling
Single crystals
Derivatives
10 Citations (Scopus)

Synthesis and fragmentation of new 2-phosphabicyclo[2.2.2]octene 2-oxides

Keglevich, G., Szelke, H., Tamás, A., Harmat, V., Ludányi, K., Vaskó, Á. G. & Tőke, L., 2002, In : Heteroatom Chemistry. 13, 7, p. 626-632 7 p.

Research output: Article

Phosphorylation
X ray analysis
Photolysis
Ultraviolet radiation
Oxides
2001
11 Citations (Scopus)

Novel ring transformations of condensed [1,2,4]triazolo[4,3-b]pyridazine-6(5H)-one-3(2H)-thiones effected by dialkyl-acetylenedicarboxylates

Simó, M., Csámpai, A., Harmat, V., Barabás, O. & Magyarfalvy, G., aug. 13 2001, In : Tetrahedron. 57, 33, p. 7191-7198 8 p.

Research output: Article

Thiones
Heating
Derivatives
Temperature
Substrates
2000
31 Citations (Scopus)
Calmodulin
Trifluoperazine
ethylenediamine
Type 1 Cyclic Nucleotide Phosphodiesterases
Enzyme Assays
26 Citations (Scopus)
Enantiomers
enantiomers
Cyclodextrins
pyrroles
Carboxylic acids
46 Citations (Scopus)
phosphine
Boranes
Oxides
Imides
Hexanes
9 Citations (Scopus)
cyclopropane
carboxylic acid
Carboxylic acids
carboxylic acids
sulfur
1999
20 Citations (Scopus)

Effect of a trifluoromethyl group on molecular structure: Competitive mono- and dilithiation of 1-[(trifluoromethyl)phenyl]pyrroles

Faigl, F., Fogassy, K., Szucs, E., Kovács, K., Keseru, G. M., Harmat, V., Böcskei, Z. & Tőke, L., jún. 18 1999, In : Tetrahedron. 55, 25, p. 7881-7892 12 p.

Research output: Article

Pyrroles
Molecular Structure
Molecular structure
Carboxylation
Molecular modeling
2 Citations (Scopus)

Geometry and electronic structure of silylated hydroxylamine and carbamic acid derivatives

Csonka, I. P., Mörtl, M., Knausz, D., Harmat, V. & Szepes, L., máj. 5 1999, In : Journal of Organometallic Chemistry. 579, 1-2, p. 38-44 7 p.

Research output: Article

Oxygen Compounds
Hydroxylamine
oxygen compounds
Electronic structure
Nitrogen
1998
1 Citation (Scopus)

Isostructural metabolites of two anti-Parkinson drugs

Simon, K., Harmat, V., Török, Z., Böcskei, Z. & Hermecz, I., 1998, In : Acta Crystallographica Section C: Crystal Structure Communications. 54, 6, p. 811-813 3 p.

Research output: Article

metabolites
hydrochlorides
Metabolites
Chlorides
drugs
58 Citations (Scopus)
Trifluoperazine
Calmodulin
Vinblastine
Pharmaceutical Preparations
Molecules