V. Ádám-Vizi

  • Hungary

  • 5014 Citations
  • 39 h-Index
1978 …2018
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Research Output 1978 2018

  • 5014 Citations
  • 39 h-Index
  • 112 Article
  • 5 Conference contribution
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Article
2018
1 Citation (Scopus)

Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase

Szabo, E., Mizsei, R., Wilk, P., Zambo, Z., Törőcsik, B., Weiss, M. S., Ádám-Vizi, V. & Ambrus, A., aug. 20 2018, In : Free Radical Biology and Medicine. 124, p. 214-220 7 p.

Research output: Article

Dihydrolipoamide Dehydrogenase
Crystal structure
Reactive Oxygen Species
Catalyst activity
Catalytic Domain

Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia-ANT

Chen, E., Kiebish, M. A., McDaniel, J., Niedzwiecka, K., Kucharczyk, R., Ravasz, D., Gao, F., Narain, N. R., Sarangarajan, R., Seyfried, T. N., Ádám-Vizi, V. & Chinopoulos, C., dec. 1 2018, In : Scientific Reports. 8, 1, 5915.

Research output: Article

ATP Translocases Mitochondrial ADP
Artemia
Membrane Proteins
Yeasts
Mitochondrial Membranes
3 Citations (Scopus)
Phosphorylation
Quinones
NAD
Ketoglutarate Dehydrogenase Complex
Dihydrolipoamide Dehydrogenase
2017
5 Citations (Scopus)
gamma-Aminobutyric Acid
Phosphorylation
Aminooxyacetic Acid
Vigabatrin
Mitochondria
7 Citations (Scopus)
Reactive Oxygen Species
Biochemical Phenomena
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
Dihydrolipoamide Dehydrogenase
Thioctic Acid
93 Citations (Scopus)

The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species

Bordt, E. A., Clerc, P., Roelofs, B. A., Saladino, A. J., Tretter, L., Ádám-Vizi, V., Cherok, E., Khalil, A., Yadava, N., Ge, S. X., Francis, T. C., Kennedy, N. W., Picton, L. K., Kumar, T., Uppuluri, S., Miller, A. M., Itoh, K., Karbowski, M., Sesaki, H., Hill, R. B. & 1 others, Polster, B. M., márc. 27 2017, In : Developmental Cell. 40, 6, p. 583-594.e6

Research output: Article

Dynamins
Reactive Oxygen Species
Mitochondrial Dynamics
Proteins
GTP Phosphohydrolases
2016
39 Citations (Scopus)

Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage

Németh, B., Doczi, J., Csete, D., Kacso, G., Ravasz, D., Adams, D., Kiss, G., Nagy, A. M., Horvath, G., Tretter, L., Mócsai, A., Csépányi-Kömi, R., Iordanov, I., Ádám-Vizi, V. & Chinopoulos, C., jan. 1 2016, In : FASEB Journal. 30, 1, p. 286-300 15 p.

Research output: Article

Phosphorylation
Macrophages
Genes
Gene Expression
Succinic Acid
15 Citations (Scopus)

Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells

Doczi, J., Törőcsik, B., Echaniz-Laguna, A., De Camaret, B. M., Starkov, A., Starkova, N., Gál, A., Molńr, M. J., Kawamata, H., Manfredi, G., Ádám-Vizi, V. & Chinopoulos, C., máj. 25 2016, In : Scientific Reports. 6, 26700.

Research output: Article

Permeability
Calcimycin
Fibroblasts
Skeletal Muscle Fibers
Mitochondrial Swelling
1 Citation (Scopus)

Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice

Vereczki, V., Mansour, J., Pour-Ghaz, I., Bodnár, I., Pinter, O., Zelena, D., Oszwald, E., Ádám-Vizi, V. & Chinopoulos, C., jún. 13 2016, (Accepted/In press) In : Mitochondrion.

Research output: Article

Brain
alpha-Synuclein
Proteins
Prosencephalon
Permeability
7 Citations (Scopus)
Dihydrolipoamide Dehydrogenase
Deuterium
Hydrogen
Mass Spectrometry
Mutation
2 Citations (Scopus)

The total and mitochondrial lipidome of Artemia franciscana encysted embryos

Chen, E., Kiebish, M. A., McDaniel, J., Gao, F., Narain, N. R., Sarangarajan, R., Kacso, G., Ravasz, D., Seyfried, T. N., Ádám-Vizi, V. & Chinopoulos, C., nov. 1 2016, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1861, 11, p. 1727-1735 9 p.

Research output: Article

Dolphins
Artemia
Cysts
Embryonic Structures
Lipids
2015
24 Citations (Scopus)
Multienzyme Complexes
Ketoglutarate Dehydrogenase Complex
Pyruvic Acid
Reactive Oxygen Species
Escherichia coli
2014
23 Citations (Scopus)
Mitochondria
Methylene Blue
Hydrogen Peroxide
Energy Metabolism
Brain
24 Citations (Scopus)

Human 2-oxoglutarate dehydrogenase complex E1 component forms a thiamin-derived radical by aerobic oxidation of the enamine intermediate

Nemeria, N. S., Ambrus, A., Patel, H., Gerfen, G., Ádám-Vizi, V., Tretter, L., Zhou, J., Wang, J. & Jordan, F., okt. 24 2014, In : Journal of Biological Chemistry. 289, 43, p. 29859-29873 15 p.

Research output: Article

Ketoglutarate Dehydrogenase Complex
Thiamine
Multienzyme Complexes
Thiamine Pyrophosphate
Superoxides
3 Citations (Scopus)
Ligases
Neuroglia
Cerebral Cortex
Phosphorylation
Myelin Basic Protein
21 Citations (Scopus)

Mitochondrial diaphorases as NAD+ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition

Kiss, G., Konrad, C., Pour-Ghaz, I., Mansour, J. J., Németh, B., Starkov, A. A., Ádám-Vizi, V. & Chinopoulos, C., 2014, In : FASEB Journal. 28, 4, p. 1682-1697 16 p.

Research output: Article

Dihydrolipoamide Dehydrogenase
Phosphorylation
Citric Acid Cycle
NAD
Adenosine Triphosphate
2013
6 Citations (Scopus)

Exclusive neuronal expression of SUCLA2 in the human brain

Dobolyi, A., Ostergaard, E., Bagó, A. G., Dóczi, T., Palkóvits, M., Gál, A., Molnár, M. J., Ádám-Vizi, V. & Chinopoulos, C., 2013, In : Brain Structure and Function. 220, 1, p. 135-151 17 p.

Research output: Article

Neuroglia
Neurons
Brain
In Situ Hybridization
Mitochondrial Proton-Translocating ATPases
15 Citations (Scopus)
Dihydrolipoamide Dehydrogenase
Molecular Dynamics Simulation
Conformations
Molecular dynamics
Reactive Oxygen Species
31 Citations (Scopus)

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

Kiss, G., Konrad, C., Doczi, J., Starkov, A. A., Kawamata, H., Manfredi, G., Zhang, S. F., Gibson, G. E., Beal, M. F., Ádám-Vizi, V. & Chinopoulos, C., jún. 2013, In : FASEB Journal. 27, 6, p. 2393-2406 14 p.

Research output: Article

Ketoglutarate Dehydrogenase Complex
Phosphorylation
Adenosine Triphosphate
Mitochondria
Dihydrolipoamide Dehydrogenase
38 Citations (Scopus)
Reactive Oxygen Species
Oxidoreductases
Oxidative Stress
NAD
Mitochondria
5 Citations (Scopus)

The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast

Wysocka-Kapcinska, M., Törőcsik, B., Turiak, L., Tsaprailis, G., David, C. L., Hunt, A. M., Vékey, K., Ádám-Vizi, V., Kucharczyk, R. & Chinopoulos, C., szept. 20 2013, In : PLoS One. 8, 9, e74187.

Research output: Article

Bongkrekic Acid
ATP Translocases Mitochondrial ADP
Artemia
Yeast
Yeasts
2012
8 Citations (Scopus)
Crangonidae
Bongkrekic Acid
Crangon
Artemia
Permeability
17 Citations (Scopus)
Glycerolphosphate Dehydrogenase
Mitochondria
Hydrogen Peroxide
Brain
Chemical activation
21 Citations (Scopus)
Proton-Translocating ATPases
Permeability
Adenine Nucleotides
Adenosine Triphosphate
Phosphates
2011
9 Citations (Scopus)
Bongkrekic Acid
ATP Translocases Mitochondrial ADP
Dolphins
Artemia
Mitochondria
24 Citations (Scopus)

Complex contribution of cyclophilin D to Ca2+-induced permeability transition in brain mitochondria, with relation to the bioenergetic state

Doczi, J., Turiák, L., Vajda, S., Mándi, M., Törőcsik, B., Gerencser, A. A., Kiss, G., Konràd, C., Ádám-Vizi, V. & Chinopoulos, C., febr. 25 2011, In : Journal of Biological Chemistry. 286, 8, p. 6345-6353 9 p.

Research output: Article

Mitochondria
Energy Metabolism
Permeability
Brain
Calcimycin

Preface

Ádám-Vizi, V., Dienel, G. A., Schousboe, A. & McKenna, M. C., dec. 2011, In : Journal of Neuroscience Research. 89, 12, p. 1895-1896 2 p.

Research output: Article

Cytosol
Energy Metabolism
Mitochondria
Brain
9 Citations (Scopus)

Reversible inhibition of hydrogen peroxide elimination by calcium in brain mitochondria

Tretter, L., Biagioni Angeli, E., Ardestani, M. R., Goracci, G. & Ádám-Vizi, V., dec. 2011, In : Journal of Neuroscience Research. 89, 12, p. 1965-1972 8 p.

Research output: Article

Hydrogen Peroxide
Mitochondria
Calcium
Aconitate Hydratase
Brain
26 Citations (Scopus)
Dihydrolipoamide Dehydrogenase
Reactive Oxygen Species
Mutation
Circular Dichroism
Gel Chromatography
2010
111 Citations (Scopus)
Reactive Oxygen Species
Calcium
Alzheimer Disease
Mitochondria
Oxidative Stress
59 Citations (Scopus)

Forward operation of adenine nucleotide translocase during F 0F1-ATPase reversal: Critical role of matrix substrate-level phosphorylation

Chinopoulos, C., Gerencser, A. A., Mandi, M., Mathe, K., Töröcsik, B., Doczi, J., Turiak, L., Kiss, G., Konràd, C., Vajda, S., Vereczki, V., Oh, R. J. & Adam-Vizi, V., júl. 2010, In : FASEB Journal. 24, 7, p. 2405-2416 12 p.

Research output: Article

ATP Translocases Mitochondrial ADP
Phosphorylation
Mitochondria
Adenosine Triphosphatases
Adenosine Triphosphate
26 Citations (Scopus)
Mitochondria
Membrane Potentials
Reactive Oxygen Species
Brain
Calcium
49 Citations (Scopus)
Mitochondria
Adenosine Triphosphate
Pathology
Adenosine Triphosphatases
Permeability
41 Citations (Scopus)
Thermodynamics
Precipitates
Mitochondria
Adenine Nucleotides
Oxidative Phosphorylation
Mitochondria

The 'ins and outs' of Ca2+ in mitochondria.

Chinopoulos, C. & Adam-Vizi, V., szept. 2010, In : FEBS Journal. 277, 18, p. 3621 1 p.

Research output: Article

Calcium Signaling
Mitochondria
2009
51 Citations (Scopus)

A novel kinetic assay of mitochondrial ATP-ADP exchange rate mediated by the ANT

Chinopoulos, C., Vajda, S., Csanády, L., Mándi, M., Mathe, K. & Ádám-Vizi, V., 2009, In : Biophysical Journal. 96, 6, p. 2490-2504 15 p.

Research output: Article

ATP Translocases Mitochondrial ADP
Adenosine Diphosphate
Adenosine Triphosphate
Heart Mitochondria
Liver Mitochondrion
11 Citations (Scopus)

A re-evaluation of the role of matrix acidification in uncoupler-induced Ca2+ release from mitochondria

Vajda, S., Mándi, M., Konràd, C., Kiss, G., Ambrus, A., Ádám-Vizi, V. & Chinopoulos, C., máj. 2009, In : FEBS Journal. 276, 10, p. 2713-2724 12 p.

Research output: Article

Oligomycins
Mitochondria
Acidification
Phosphates
Depolarization
36 Citations (Scopus)
Ketoglutarate Dehydrogenase Complex
Thioctic Acid
Reactive Oxygen Species
NAD
Dihydrolipoamide Dehydrogenase
12 Citations (Scopus)
Dihydrolipoamide Dehydrogenase
Flavin-Adenine Dinucleotide
Oxidoreductases
Enzymes
Branched Chain Amino Acids
8 Citations (Scopus)
Dihydrolipoamide Dehydrogenase
Proteins
Purification
Inclusion Bodies
Affinity chromatography
2008
26 Citations (Scopus)

H2O2 generation is decreased by calcium in isolated brain mitochondria

Komary, Z., Tretter, L. & Ádám-Vizi, V., júl. 2008, In : BBA - Bioenergetics. 1777, 7-8, p. 800-807 8 p.

Research output: Article

Mitochondria
Brain
NAD
Calcium
Depolarization
8 Citations (Scopus)
Puromycin
Endothelial Cells
Brain
Glass
Claudin-5
39 Citations (Scopus)

Mitochondrial swelling measurement in situ by optimized spatial filtering: Astrocyte-neuron differences

Gerencser, A. A., Doczi, J., Törőcsik, B., Bossy-Wetzel, E. & Ádám-Vizi, V., szept. 1 2008, In : Biophysical Journal. 95, 5, p. 2583-2598 16 p.

Research output: Article

Mitochondrial Swelling
Thinness
Astrocytes
Neurons
Mitochondria
2007
82 Citations (Scopus)

Characteristics of α-glycerophosphate-evoked H2O 2 generation in brain mitochondria

Tretter, L., Takacs, K., Hegedus, V. & Ádám-Vizi, V., febr. 2007, In : Journal of Neurochemistry. 100, 3, p. 650-663 14 p.

Research output: Article

Glycerophosphates
Mitochondria
Reactive Oxygen Species
Brain
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
27 Citations (Scopus)
Mitochondria
Bovine Serum Albumin
NAD
Reactive Oxygen Species
Brain
31 Citations (Scopus)
Glycerophosphates
Electron Transport
Mitochondria
Calcium
Brain
41 Citations (Scopus)
Succinic Acid
Bovine Serum Albumin
Membrane Potentials
Reactive Oxygen Species
Mitochondria
39 Citations (Scopus)
Mitochondria
Reactive Oxygen Species
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
Depolarization
Veratridine