• 7005 Citations
  • 26 h-Index
19982019

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Article
2019

No correlation between endo-and exoskeletal regenerative capacities in teleost species

Pápai, N., Kagan, F., Csikós, G., Kosztelnik, M., Vellai, T. & Varga, M., jan. 1 2019, In : Fishes. 4, 4, 51.

Research output: Article

Open Access

Suppression of AMPK/aak-2 by NRF2/SKN-1 downregulates autophagy during prolonged oxidative stress

Kosztelnik, M., Kurucz, A., Papp, D., Jones, E., Sigmond, T., Barna, J., Traka, M. H., Lorincz, T., Szarka, A., Banhegyi, G., Vellai, T., Korcsmaros, T. & Kapuy, O., jan. 1 2019, In : FASEB Journal. 33, 2, p. 2372-2387 16 p.

Research output: Article

7 Citations (Scopus)

The human ABCB6 protein is the functional homologue of HMT-1 proteins mediating cadmium detoxification

Rakvács, Z., Kucsma, N., Gera, M., Igriczi, B., Kiss, K., Barna, J., Kovács, D., Vellai, T., Bencs, L., Reisecker, J. M., Szoboszlai, N. & Szakács, G., jan. 1 2019, In : Cellular and Molecular Life Sciences.

Research output: Article

Open Access
1 Citation (Scopus)
2018

Developmentally regulated autophagy is required for eye formation in Drosophila

Billes, V., Kovács, T., Manzéger, A., Lőrincz, P., Szincsák, S., Regős, Á., Kulcsár, P. I., Korcsmáros, T., Lukácsovich, T., Hoffmann, G., Erdélyi, M., Mihály, J., Takács-Vellai, K., Sass, M. & Vellai, T., szept. 2 2018, In : Autophagy. 14, 9, p. 1499-1519 21 p.

Research output: Article

2 Citations (Scopus)

Functional fine-tuning between bacterial DNA recombination initiation and quality control systems

Ferencziová, V., Harami, G. M., Németh, J. B., Vellai, T. & Kovács, M., febr. 1 2018, In : PLoS One. 13, 2, e0192483.

Research output: Article

Highly efficient RNAi and Cas9-based auto-cloning systems for C. Elegans research

Sturm, Á., Saskoï, É., Tibor, K., Weinhardt, N. & Vellai, T., jan. 1 2018, In : Nucleic acids research. 46, 17, e105.

Research output: Article

4 Citations (Scopus)

Prediction and characterization of human ageing-related proteins by using machine learning

Kerepesi, C., Daróczy, B., Sturm, Á., Vellai, T. & Benczúr, A., dec. 1 2018, In : Scientific Reports. 8, 1, 4094.

Research output: Article

12 Citations (Scopus)

Roles of heat shock factor 1 beyond the heat shock response

Barna, J., Csermely, P. & Vellai, T., máj. 17 2018, (Accepted/In press) In : Cellular and Molecular Life Sciences. p. 1-20 20 p.

Research output: Article

23 Citations (Scopus)

Sex-specific regulation of aging in Caenorhabditis elegans

Hotzi, B., Kosztelnik, M., Hargitai, B., Takács-Vellai, K., Barna, J., Bördén, K., Málnási-Csizmadia, A., Lippai, M., Ortutay, C., Bacquet, C., Pasparaki, A., Arányi, T., Tavernarakis, N. & Vellai, T., jún. 2018, In : Aging cell. 17, 3, e12724.

Research output: Article

4 Citations (Scopus)
Open Access
13 Citations (Scopus)
2017

Mannich Curcuminoids as Potent Anticancer Agents

Gyuris, M., Hackler, L., Nagy, L. I., Alföldi, R., Rédei, E., Marton, A., Vellai, T., Faragó, N., Ózsvári, B., Hetényi, A., Tóth, G., Sipos, P., Kanizsai, I. & Puskás, L., júl. 1 2017, In : Archiv der Pharmazie. 350, 7, e1700005.

Research output: Article

13 Citations (Scopus)

Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies

Módos, D., Bulusu, K. C., Fazekas, D., Kubisch, J., Brooks, J., Marczell, I., Szabó, P. M., Vellai, T., Csermely, P., Lenti, K., Bender, A. & Korcsmáros, T., dec. 1 2017, In : npj Systems Biology and Applications. 3, 1, 2.

Research output: Article

7 Citations (Scopus)
2016

AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects

Papp, D., Kovács, T., Billes, V., Varga, M., Tarnóci, A., Hackler, L., Puskás, L., Liliom, H., Tárnok, K., Schlett, K., Borsy, A., Pádár, Z., Kovács, A., Hegedűs, K., Juhász, G., Komlós, M., Erdős, A., Gulyás, B. & Vellai, T., jan. 1 2016, In : Autophagy. 12, 2, p. 273-286 14 p.

Research output: Article

19 Citations (Scopus)

AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease

Billesa, V., Kovacs, T., Hotzi, B., Manzeger, A., Tagscherer, K., Komlos, M., Tarnocia, A., Padar, Z., Erdos, A., Bjelik, A., Legradi, A., Gulya, K., Gulyas, B. & Vellai, T., jan. 1 2016, In : Journal of Huntington's Disease. 5, 2, p. 133-147 15 p.

Research output: Article

11 Citations (Scopus)

SignaFish: A Zebrafish-specific signaling pathway resource

Csályi, K., Fazekas, D., Kadlecsik, T., Türei, D., Gul, L., Horváth, B., Módos, D., Demeter, A., Pápai, N., Lenti, K., Csermely, P., Vellai, T., Korcsmáros, T. & Varga, M., jan. 1 2016, In : Zebrafish. 13, 6, p. 541-544 4 p.

Research output: Article

1 Citation (Scopus)
2015

Autophagy in zebrafish

Varga, M., Fodor, E. & Vellai, T., márc. 15 2015, In : Methods. 75, p. 172-180 9 p.

Research output: Article

25 Citations (Scopus)

Autophagy regulatory network - A systemslevel bioinformatics resource for studying the mechanism and regulation of autophagy

Türei, D., Földvári-Nagy, L., Fazekas, D., Módos, D., Kubisch, J., Kadlecsik, T., Demeter, A., Lenti, K., Csermely, P., Vellai, T. & Korcsmáros, T., jan. 1 2015, In : Autophagy. 11, 1, p. 155-165 11 p.

Research output: Article

39 Citations (Scopus)
7 Citations (Scopus)

The mechanism of ageing: Primary role of transposable elements in genome disintegration

Sturm, Á., Ivics, Z. & Vellai, T., máj. 1 2015, In : Cellular and Molecular Life Sciences. 72, 10, p. 1839-1847 9 p., 1896.

Research output: Article

21 Citations (Scopus)
2014

Autophagy is required for zebrafish caudal fin regeneration

Varga, M., Sass, M., Papp, D., Takács-Vellai, K., Kobolak, J., Dinnyés, A., Klionsky, D. J. & Vellai, T., ápr. 1 2014, In : Cell Death and Differentiation. 21, 4, p. 547-556 10 p.

Research output: Article

40 Citations (Scopus)

NDK-1, the homolog of NM23-H1/H2 regulates cell migration and apoptotic engulfment in C. elegans

Fancsalszky, L., Monostori, E., Farkas, Z., Pourkarimi, E., Masoudi, N., Hargitai, B., Bosnar, M. H., Deželjin, M., Zsákai, A., Vellai, T., Mehta, A. & Takács-Vellai, K., márc. 21 2014, In : PloS one. 9, 3, e92687.

Research output: Article

19 Citations (Scopus)
2013

Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy

Sengupta, T., Torgersen, M. L., Kassahun, H., Vellai, T., Simonsen, A. & Nilsen, H., jan. 1 2013, In : Nature communications. 4, 2578.

Research output: Article

34 Citations (Scopus)
2 Citations (Scopus)

SignaLink 2 - a signaling pathway resource with multi-layered regulatory networks.

Fazekas, D., Koltai, M., Türei, D., Módos, D., Pálfy, M., Dúl, Z., Zsákai, L., Szalay-Beko, M., Lenti, K., Farkas, I. J., Vellai, T., Csermely, P. & Korcsmáros, T., 2013, In : Unknown Journal. 7, 1 p.

Research output: Article

93 Citations (Scopus)
Open Access
4 Citations (Scopus)

The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans

Masoudi, N., Fancsalszky, L., Pourkarimi, E., Vellai, T., Alexa, A., Reményi, A., Gartner, A., Mehta, A. & Takács-Vellai, K., aug. 15 2013, In : Development (Cambridge). 140, 16, p. 3486-3495 10 p.

Research output: Article

23 Citations (Scopus)
2012

A novel actin binding site of myosin required for effective muscle contraction

Várkuti, B. H., Yang, Z., Kintses, B., Erdélyi, P., Bárdos-Nagy, I., Kovács, A. L., Hári, P., Kellermayer, M., Vellai, T. & Málnási-Csizmadia, A., márc. 1 2012, In : Nature Structural and Molecular Biology. 19, 3, p. 299-306 8 p.

Research output: Article

37 Citations (Scopus)

Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging

Barna, J., Princz, A., Kosztelnik, M., Hargitai, B., Takács-Vellai, K. & Vellai, T., jan. 1 2012, In : BMC developmental biology. 12, 1, 32.

Research output: Article

26 Citations (Scopus)
2011

Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans

Erdélyi, P., Borsos, É., Takács-Vellai, K., Kovács, T., Kovács, A. L., Sigmond, T., Hargitai, B., Pásztor, L., SenGupta, T., Dengg, M., Pécsi, I., Tóth, J., Nilsen, H., Vértessy, B. G. & Vellai, T., máj. 1 2011, In : Journal of cell science. 124, 9, p. 1510-1518 9 p.

Research output: Article

Open Access
27 Citations (Scopus)

Signalogs: Orthology-based identification of novel signaling pathway components in three metazoans

Korcsmáros, T., Szalay, M. S., Rovó, P., Palotai, R., Fazekas, D., Lenti, K., FarkasIllé, I. J., Csermely, P. & Vellai, T., jan. 1 2011, In : PloS one. 6, 5, e19240.

Research output: Article

19 Citations (Scopus)
2010

A second report from the EMBO conference on autophagy: Mechanism, regulation and selectivity of autophagy

Vellai, T. & Klionsky, D. J., jan. 1 2010, In : Autophagy. 6, 1, p. 197-198 2 p.

Research output: Article

2 Citations (Scopus)
12 Citations (Scopus)

Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery

Korcsmáros, T., Farkas, I. J., Szalay, M. S., Rovó, P., Fazekas, D., Spiró, Z., Bode, C., Lenti, K., Vellai, T. & Csermely, P., jún. 11 2010, In : Bioinformatics. 26, 16, p. 2042-2050 9 p., btq310.

Research output: Article

59 Citations (Scopus)
2009

Identifying novel genes involved in both deer physiological and human pathological osteoporosis

Borsy, A., Podani, J., Stéger, V., Balla, B., Horváth, A., Kósa, J. P., Gyurján, I., Molnár, A., Szabolcsi, Z., Szabó, L., Jakó, E., Zomborszky, Z., Nagy, J., Semsey, S., Vellai, T., Lakatos, P. & Orosz, L., márc. 1 2009, In : Molecular Genetics and Genomics. 281, 3, p. 301-313 13 p.

Research output: Article

17 Citations (Scopus)

The regulation of aging: does autophagy underlie longevity?

Vellai, T., Takács-Vellai, K., Sass, M. & Klionsky, D. J., okt. 1 2009, In : Trends in Cell Biology. 19, 10, p. 487-494 8 p.

Research output: Article

96 Citations (Scopus)

TRA-1/GLI controls the expression of the Hox gene lin-39 during C. elegans vulval development

Szabó, E., Hargitai, B., Regos, Á., Tihanyi, B., Barna, J., Borsos, É., Takács-Vellai, K. & Vellai, T., jún. 15 2009, In : Developmental Biology. 330, 2, p. 339-348 10 p.

Research output: Article

15 Citations (Scopus)

Xol-1, the master sex-switch gene in C. elegans, is a transcriptional target of the terminal sex-determining factor TRA-1

Hargitai, B., Kutnyánszky, V., Blauwkamp, T. A., Steták, A., Csankovszki, G., Takács-Vellai, K. & Vellai, T., szept. 25 2009, In : Development. 136, 23, p. 3881-3887 7 p.

Research output: Article

17 Citations (Scopus)
2008

Distribution and evolution of short tandem repeats in closely related bacterial genomes

Kassai-Jáger, E., Ortutay, C., Tóth, G., Vellai, T. & Gáspári, Z., febr. 29 2008, In : Gene. 410, 1, p. 18-25 8 p.

Research output: Article

19 Citations (Scopus)

Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans

Tóth, M. L., Sigmond, T., Borsos, É., Barna, J., Erdélyi, P., Takács-Vellai, K., Orosz, L., Kovács, A. L., Csikós, G., Sass, M. & Vellai, T., ápr. 1 2008, In : Autophagy. 4, 3, p. 330-338 9 p.

Research output: Article

Open Access
255 Citations (Scopus)

Qualitative and quantitative characterization of autophagy in Caenorhabditis elegans by electron microscopy.

Sigmond, T., Fehér, J., Baksa, A., Pásti, G., Pálfia, Z., Takács-Vellai, K., Kovács, J., Vellai, T. & Kovács, A. L., 2008, In : Methods in enzymology. 451, p. 467-491 25 p.

Research output: Article

16 Citations (Scopus)

Regulation of cell growth by autophagy

Vellai, T., Bicsák, B., Tóth, M. L., Takács-Vellai, K. & Kovács, A. L., máj. 16 2008, In : Autophagy. 4, 4, p. 507-509 3 p.

Research output: Article

Open Access
28 Citations (Scopus)
2007

Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans

Aladzsity, I., Tóth, M. L., Sigmond, T., Szabó, E., Bicsák, B., Barna, J., Regos, Á., Orosz, L., Kovács, A. L. & Vellai, T., szept. 1 2007, In : Genetics. 177, 1, p. 655-660 6 p.

Research output: Article

28 Citations (Scopus)

Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans

Tóth, M. L., Simon, P., Kovács, A. L. & Vellai, T., márc. 15 2007, In : Journal of cell science. 120, 6, p. 1134-1141 8 p.

Research output: Article

53 Citations (Scopus)

Transcriptional control of Notch signaling by a HOX and a PBX/EXD protein during vulval development in C. elegans

Takács-Vellai, K., Vellai, T., Chen, E. B., Zhang, Y., Guerry, F., Stern, M. J. & Müller, F., febr. 15 2007, In : Developmental Biology. 302, 2, p. 661-669 9 p.

Research output: Article

35 Citations (Scopus)
2006
29 Citations (Scopus)

The maintenance of sex in bacteria is ensured by its potential to reload genes

Szöllosi, G. J., Derényi, I. & Vellai, T., dec. 1 2006, In : Genetics. 174, 4, p. 2173-2180 8 p.

Research output: Article

14 Citations (Scopus)
2005

Inactivation of the autophagy Gene bec-1 triggers apoptotic cell death in C. elegans

Takacs-Vellai, K., Vellai, T., Puoti, A., Passannante, M., Wicky, C., Streit, A., Kovacs, A. L. & Müller, F., aug. 23 2005, In : Current Biology. 15, 16, p. 1513-1517 5 p.

Research output: Article

172 Citations (Scopus)
2004

The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development

Menzel, O., Vellai, T., Takacs-Vellai, K., Reymond, A., Mueller, F., Antonarakis, S. E. & Guipponi, M., aug. 1 2004, In : Genomics. 84, 2, p. 320-330 11 p.

Research output: Article

16 Citations (Scopus)
2003

Influence of TOR kinase on lifespan in C. elegans

Vellai, T., Takacs-Vellai, K., Zhang, Y., Kovacs, A. L., Orosz, L. & Müller, F., dec. 11 2003, In : Nature. 426, 6967, 1 p.

Research output: Article

700 Citations (Scopus)

Speciation in Chlamydia: Genomewide Phylogenetic Analyses Identified a Reliable Set of Acquired Genes

Ortutay, C., Gáspári, Z., Tóth, G., Jáger, E., Vida, G., Orosz, L. & Vellai, T., dec. 1 2003, In : Journal of Molecular Evolution. 57, 6, p. 672-680 9 p.

Research output: Article

18 Citations (Scopus)