• 6930 Citations
  • 34 h-Index
1990 …2016
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Research Output 1990 2016

  • 6930 Citations
  • 34 h-Index
  • 77 Article
  • 1 Comment/debate
2016
17 Citations (Scopus)
Inositol
Epidermal Growth Factor Receptor
Signal Transduction
Biosensing Techniques
Type C Phospholipases

Correction: Improved methodical approach for quantitative BRET analysis of G protein coupled receptor dimerization

Szalai, B., Hoffmann, P., Prokop, S., Erdélyi, L., Várnai, P. & Hunyady, L., máj. 1 2016, In : PLoS One. 11, 5, e0156824.

Research output: Comment/debate

Dimerization
G-Protein-Coupled Receptors
Chemical analysis
29 Citations (Scopus)

Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-golgi junctions

Sohn, M., Ivanova, P., Brown, H. A., Toth, D. J., Várnai, P., Kim, Y. J. & Balla, T., ápr. 19 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 16, p. 4314-4319 6 p.

Research output: Article

Phosphatidylserines
Cell Membrane
Mutation
Short Rib-Polydactyly Syndrome
Enzymes
2015
13 Citations (Scopus)

Investigation of the fate of type I angiotensin receptor after biased activation

Szakadáti, G., Tóth, A. D., Oláh, I., Erdélyi, L. S., Balla, T., Várnai, P., Hunyady, L. & Balla, A., jún. 1 2015, In : Molecular Pharmacology. 87, 6, p. 972-981 10 p.

Research output: Article

Arrestin
Angiotensin Receptors
Endocytosis
Angiotensin II
rab5 GTP-Binding Proteins
12 Citations (Scopus)

Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors

Gulyás, G., Tóth, J., Tóth, D. J., Kurucz, I., Hunyady, L., Balla, T. & Várnai, P., máj. 1 2015, In : PLoS One. 10, 5, e0125601.

Research output: Article

Inositol 1,4,5-Trisphosphate
biosensors
Energy Transfer
Biosensing Techniques
energy transfer
33 Citations (Scopus)
Voltage-Dependent Anion Channels
Zebrafish
Fibroblasts
Apoptosis
Ion Transport
14 Citations (Scopus)

Mutation in the V2 vasopressin receptor gene, AVPR2, causes nephrogenic syndrome of inappropriate diuresis

Erdélyi, L. S., Mann, W. A., Morris-Rosendahl, D. J., Groß, U., Nagel, M., Várnai, P., Balla, A. & Hunyady, L., nov. 1 2015, In : Kidney International. 88, 5, p. 1070-1078 9 p.

Research output: Article

Vasopressin Receptors
Diuresis
Arrestin
Mutation
Cyclic AMP
67 Citations (Scopus)

Trans-mitochondrial coordination of cristae at regulated membrane junctions

Picard, M., McManus, M. J., Csordás, G., Várnai, P., Dorn, G. W., Williams, D., Hajnóczky, G. & Wallace, D. C., febr. 17 2015, In : Nature Communications. 6, 6259.

Research output: Article

Mitochondria
mitochondria
membranes
Membranes
organelles
2014
8 Citations (Scopus)
Nephrogenic Diabetes Insipidus
Arrestin
Deamino Arginine Vasopressin
Vasopressin Receptors
Hemagglutinins
31 Citations (Scopus)

Distribution and Apoptotic Function of Outer Membrane Proteins Depend on Mitochondrial Fusion

Weaver, D., Eisner, V., Liu, X., Várnai, P., Hunyady, L., Gross, A. & Hajnóczky, G., jún. 5 2014, In : Molecular Cell. 54, 5, p. 870-878 9 p.

Research output: Article

Mitochondrial Dynamics
Mitochondrial Membranes
Membrane Proteins
Mitochondrial Proteins
Mitochondria
22 Citations (Scopus)

Improved methodical approach for quantitative BRET analysis of G protein coupled receptor dimerization

Szalai, B., Hoffmann, P., Prokop, S., Erdélyi, L., Várnai, P. & Hunyady, L., okt. 17 2014, In : PLoS One. 9, 10, e109503.

Research output: Article

Bioluminescence
dimerization
Dimerization
Energy Transfer
G-Protein-Coupled Receptors
15 Citations (Scopus)
Phosphatidylinositol 4,5-Diphosphate
G-Protein-Coupled Receptors
Phosphatidylinositols
Endocytosis
Cell Membrane
30 Citations (Scopus)

Allosteric interactions within the AT 1 angiotensin receptor homodimer: Role of the conserved DRY motif

Szalai, B., Barkai, L., Turu, G., Szidonya, L., Várnai, P. & Hunyady, L., aug. 15 2012, In : Biochemical Pharmacology. 84, 4, p. 477-485 9 p.

Research output: Article

Angiotensin Receptors
Protein Subunits
Dimers
Bioluminescence
Conformations
33 Citations (Scopus)

Calcium transport across the inner mitochondrial membrane: Molecular mechanisms and pharmacology

Csordás, G., Várnai, P., Golenár, T., Sheu, S. S. & Hajnóczky, G., ápr. 28 2012, In : Molecular and Cellular Endocrinology. 353, 1-2, p. 109-113 5 p.

Research output: Article

Mitochondrial Membranes
Pharmacology
Calcium
Membranes
RNA Interference
13 Citations (Scopus)

Mapping of the localization of type 1 angiotensin receptor in membrane microdomains using bioluminescence resonance energy transfer-based sensors

Balla, A., Tóth, D. J., Soltész-Katona, E., Szakadáti, G., Erdélyi, L. S., Várnai, P. & Hunyady, L., márc. 16 2012, In : Journal of Biological Chemistry. 287, 12, p. 9090-9099 10 p.

Research output: Article

Membrane Microdomains
Bioluminescence
Angiotensin Type 1 Receptor
Energy Transfer
Cell membranes
19 Citations (Scopus)

Switch from ER-mitochondrial to SR-mitochondrial calcium coupling during muscle differentiation

Yi, M., Weaver, D., Eisner, V., Várnai, P., Hunyady, L., Ma, J., Csordás, G. & Hajnóczky, G., nov. 2012, In : Cell Calcium. 52, 5, p. 355-365 11 p.

Research output: Article

Myoblasts
Sarcoplasmic Reticulum
Ryanodine Receptor Calcium Release Channel
Skeletal Muscle Fibers
Endoplasmic Reticulum
2011
6 Citations (Scopus)
Bioluminescence
trans-Golgi Network
Energy Transfer
Biosensing Techniques
Biosensors
30 Citations (Scopus)

The effect of OPA1 on mitochondrial Ca 2+ signaling

Fülöp, L., Szanda, G., Enyedi, B., Várnai, P. & Spät, A., szept. 29 2011, In : PLoS One. 6, 9, e25199.

Research output: Article

Mitochondria
Membranes
uptake mechanisms
mitochondria
Autosomal Dominant Optic Atrophy
2010
148 Citations (Scopus)

Activation of STIM1-Orai1 involves an intramolecular switching mechanism

Korzeniowski, M. K., Manjarrés, I. M., Várnai, P. & Balla, T., nov. 16 2010, In : Science Signaling. 3, 148, ra82.

Research output: Article

Chemical activation
Molecules
Mutation
Stromal Interaction Molecule 1
Clamping devices
100 Citations (Scopus)
Phosphatidylinositols
Cell Membrane
Phosphoric Monoester Hydrolases
Vesicular Transport Adaptor Proteins
Phosphatidylinositol 4,5-Diphosphate
9 Citations (Scopus)
Purinergic P2X Receptors
Cystic Fibrosis
Adenosine Triphosphate
Epithelial Cells
Divalent Cations
9 Citations (Scopus)
Purinergic P2X Receptors
Cystic Fibrosis
Adenosine Triphosphate
Epithelial Cells
Divalent Cations
9 Citations (Scopus)
Purinergic P2X Receptors
Cystic Fibrosis
Adenosine Triphosphate
Epithelial Cells
Divalent Cations
9 Citations (Scopus)
Purinergic P2X Receptors
Cystic Fibrosis
Adenosine Triphosphate
Epithelial Cells
Divalent Cations
9 Citations (Scopus)

Calcium entry is regulated by Zn2+ in relation to extracellular ionic environment in human airway epithelial cells

Hargitai, D., Pataki, Á., Raffai, G., Füzi, M., Dankó, T., Csernoch, L., Várnai, P., Szigeti, G. & Zsembery, A., jan. 31 2010, In : Respiratory Physiology and Neurobiology. 170, 1, p. 67-75 9 p.

Research output: Article

Purinergic P2X Receptors
Cystic Fibrosis
Adenosine Triphosphate
Epithelial Cells
Divalent Cations
369 Citations (Scopus)

Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface

Csordás, G., Várnai, P., Golenár, T., Roy, S., Purkins, G., Schneider, T. G., Balla, T. & Hajnóczky, G., júl. 2010, In : Molecular Cell. 39, 1, p. 121-132 12 p.

Research output: Article

Mitochondria
Calcium
Calcium Signaling
Cell Membrane
Apoptosis
88 Citations (Scopus)
Protein folding
Endoplasmic Reticulum
Disulfides
Oxidation-Reduction
Protein Disulfide-Isomerases
6 Citations (Scopus)
Transcription
RNA
Genomics
genomics
Untranslated RNA
2009
102 Citations (Scopus)

Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides

Korzeniowski, M. K., Popovic, M. A., Szentpetery, Z., Várnai, P., Stojilkovic, S. S. & Balla, T., júl. 31 2009, In : Journal of Biological Chemistry. 284, 31, p. 21027-21035 9 p.

Research output: Article

Cell membranes
Phosphatidylinositols
Phosphatidylinositol 4,5-Diphosphate
Cell Membrane
1-Phosphatidylinositol 4-Kinase
22 Citations (Scopus)

Mechanisms of angiotensin II-mediated regulation of aldosterone synthase expression in H295R human adrenocortical and rat adrenal glomerulosa cells

Szekeres, M., Turu, G., Orient, A., Szalai, B., Süpeki, K., Cserzo, M., Várnai, P. & Hunyady, L., ápr. 29 2009, In : Molecular and Cellular Endocrinology. 302, 2, p. 244-253 10 p.

Research output: Article

Cytochrome P-450 CYP11B2
Zona Glomerulosa
Angiotensin II
Rats
Calcium-Calmodulin-Dependent Protein Kinases
48 Citations (Scopus)

Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors

Turu, G., Várnai, P., Gyombolai, P., Szidonya, L., Offertaler, L., Bagdy, G., Kunos, G. & Hunyady, L., jún. 19 2009, In : Journal of Biological Chemistry. 284, 25, p. 16914-16921 8 p.

Research output: Article

Gq-G11 GTP-Binding Protein alpha Subunits
Cannabinoid Receptor CB1
Angiotensins
Transcriptional Activation
Endocannabinoids
123 Citations (Scopus)
Calcium
Endoplasmic Reticulum
Molecules
Proteins
Cell membranes
51 Citations (Scopus)
Phosphatidylinositols
Membranes
Personnel Selection
Protein Domains
Eukaryotic Cells
2008
15 Citations (Scopus)
Prolactin-Releasing Hormone
Tyrosine 3-Monooxygenase
Rats
Brain
Brain Stem
106 Citations (Scopus)

c-Met must translocate to the nucleus to initiate calcium signals

Gomes, D. A., Rodrigues, M. A., Leite, M. F., Gomez, M. V., Várnai, P., Balla, T., Bennett, A. M. & Nathanson, M. H., febr. 15 2008, In : Journal of Biological Chemistry. 283, 7, p. 4344-4351 8 p.

Research output: Article

Hepatocyte Growth Factor
Calcium
Cytoplasm
Karyopherins
Inositol 1,4,5-Trisphosphate
38 Citations (Scopus)

Live cell imaging of phosphoinositides with expressed inositide binding protein domains

Várnai, P. & Balla, T., nov. 2008, In : Methods. 46, 3, p. 167-176 10 p.

Research output: Article

Phosphatidylinositols
Carrier Proteins
Calcium Signaling
Inositol
Imaging techniques
120 Citations (Scopus)

Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIα

Balla, A., Yeun, J. K., Várnai, P., Szentpetery, Z., Knight, Z., Shokat, K. M. & Balla, T., febr. 2008, In : Molecular Biology of the Cell. 19, 2, p. 711-721 11 p.

Research output: Article

1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Maintenance
Cell Membrane
Hormones
2007
152 Citations (Scopus)

Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains

Cohen, L. A., Honda, A., Várnai, P., Brown, F. D., Balla, T. & Donaldson, J. G., jún. 2007, In : Molecular Biology of the Cell. 18, 6, p. 2244-2253 10 p.

Research output: Article

Guanosine Triphosphate
Cell Membrane
Guanine Nucleotide Exchange Factors
COS Cells
GTP Phosphohydrolases
10 Citations (Scopus)

AT1 receptor blocker-insensitive mutant AT1A angiotensin receptors reveal the presence of G protein-independent signaling in C9 cells

Szidonya, L., Süpeki, K., Karip, E., Turu, G., Várnai, P., Clark, A. J. L. & Hunyady, L., máj. 15 2007, In : Biochemical Pharmacology. 73, 10, p. 1582-1592 11 p.

Research output: Article

Angiotensin Receptors
GTP-Binding Proteins
Angiotensin II
Signal Transduction
Signal transduction
203 Citations (Scopus)

Dual regulation of TRPV1 by phosphoinositides

Lukacs, V., Thyagarajan, B., Várnai, P., Balla, A., Balla, T. & Rohacs, T., jún. 27 2007, In : Journal of Neuroscience. 27, 26, p. 7070-7080 11 p.

Research output: Article

Phosphatidylinositol 4,5-Diphosphate
Phosphatidylinositols
Capsaicin
Type C Phospholipases
vanilloid receptor subtype 1
66 Citations (Scopus)

Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate

Van Zeijl, L., Ponsioen, B., Giepmans, B. N. G., Ariaens, A., Postma, F. R., Várnai, P., Balla, T., Divecha, N., Jalink, K. & Moolenaar, W. H., jún. 4 2007, In : Journal of Cell Biology. 177, 5, p. 881-891 11 p.

Research output: Article

Connexin 43
Phosphatidylinositol 4,5-Diphosphate
Phosphatidylinositols
Cell Communication
Phospholipases
40 Citations (Scopus)
Phosphatidylinositols
Visualization
Lipids
Membranes
Proteins
191 Citations (Scopus)
Cell membranes
Endoplasmic Reticulum
Visualization
Cell Membrane
Membranes
2006
603 Citations (Scopus)

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels

Szabadkai, G., Bianchi, K., Várnai, P., De Stefani, D., Wieckowski, M. R., Cavagna, D., Nagy, A. I., Balla, T. & Rizzuto, R., dec. 18 2006, In : Journal of Cell Biology. 175, 6, p. 901-911 11 p.

Research output: Article

Endoplasmic Reticulum
Voltage-Dependent Anion Channels
Inositol 1,4,5-Trisphosphate Receptors
Molecular Chaperones
Mitochondrial Membranes
110 Citations (Scopus)
Phosphatidylinositols
Inositol
Lipids
Membranes
Cell Fractionation
31 Citations (Scopus)

Mitochondrial Ca2+ uptake with and without the formation of high-Ca2+ microdomains

Szanda, G., Koncz, P., Várnai, P. & Spät, A., nov. 2006, In : Cell Calcium. 40, 5-6, p. 527-537 11 p.

Research output: Article

Reticulum
Mitochondria
Angiotensin II
Cell Membrane
Luteal Cells
251 Citations (Scopus)
Phosphatidylinositols
phosphoinositide 5-phosphatase
Tacrolimus Binding Protein 1A
Phosphatidylinositol 4,5-Diphosphate
Cell Membrane
713 Citations (Scopus)

Structural and functional features and significance of the physical linkage between ER and mitochondria

Csordás, G., Renken, C., Várnai, P., Walter, L., Weaver, D., Buttle, K. F., Balla, T., Mannella, C. A. & Hajnóczky, G., szept. 25 2006, In : Journal of Cell Biology. 174, 7, p. 915-921 7 p.

Research output: Article

Endoplasmic Reticulum
Mitochondria
Cell Survival
Electron Microscope Tomography
Smooth Endoplasmic Reticulum
2005
170 Citations (Scopus)
1-Phosphatidylinositol 4-Kinase
Cell Membrane
Down-Regulation
Cytoplasmic Vesicles
COS Cells