M. Fuxreiter

  • Hungary

  • 5409 Citations
  • 33 h-Index
19942019

Research output per year

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Research Output

2019

Altered dynamics may drift pathological fibrillization in membraneless organelles

Tüű-Szabó, B., Hoffka, G., Duro, N. & Fuxreiter, M., okt. 2019, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1867, 10, p. 988-998 11 p.

Research output: Article

5 Citations (Scopus)
33 Citations (Scopus)

Specific and Fuzzy Interactions Cooperate in Modulating Protein Half-Life

Sharma, R., Demény, M., Ambrus, V., Király, S. B., Kurtán, T., Gatti-Lafranconi, P. & Fuxreiter, M., ápr. 5 2019, In : Journal of molecular biology. 431, 8, p. 1700-1707 8 p.

Research output: Article

2018

Experimental Characterization of Fuzzy Protein Assemblies: Interactions of Paramyxoviral NTAIL Domains With Their Functional Partners

Troilo, F., Bignon, C., Gianni, S., Fuxreiter, M. & Longhi, S., 2018, Methods in Enzymology. Rhoades, E. (ed.). Academic Press Inc., p. 137-192 56 p. (Methods in Enzymology; vol. 611).

Research output: Chapter

5 Citations (Scopus)

Fuzziness in Protein Interactions—A Historical Perspective

Fuxreiter, M., aug. 3 2018, In : Journal of molecular biology. 430, 16, p. 2278-2287 10 p.

Research output: Review article

46 Citations (Scopus)

Protein Phase Separation: A New Phase in Cell Biology

Boeynaems, S., Alberti, S., Fawzi, N. L., Mittag, T., Polymenidou, M., Rousseau, F., Schymkowitz, J., Shorter, J., Wolozin, B., Van Den Bosch, L., Tompa, P. & Fuxreiter, M., jún. 2018, In : Trends in Cell Biology. 28, 6, p. 420-435 16 p.

Research output: Review article

271 Citations (Scopus)
Open Access
2 Citations (Scopus)

Towards a stochastic paradigm: From fuzzy ensembles to cellular functions

Fuxreiter, M., nov. 17 2018, In : Molecules. 23, 11, 3008.

Research output: Review article

6 Citations (Scopus)
2017

Computational analyses of the effect of novel amino acid clusters of human transglutaminase 2 on its structure and function

Thangaraju, K., Király, R., Mótyán, J. A., Ambrus, V. A., Fuxreiter, M. & Fésüs, L., márc. 1 2017, In : Amino Acids. 49, 3, p. 605-614 10 p.

Research output: Article

1 Citation (Scopus)
48 Citations (Scopus)

Fuzziness enables context dependence of protein interactions

Miskei, M., Gregus, A., Sharma, R., Duro, N., Zsolyomi, F. & Fuxreiter, M., szept. 2017, In : FEBS letters. 591, 17, p. 2682-2695 14 p.

Research output: Review article

23 Citations (Scopus)

Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2

Thangaraju, K., Király, R., Demény, M. A., Mótyán, J. A., Fuxreiter, M. & Fésüs, L., márc. 1 2017, In : PLoS One. 12, 3, e0172189.

Research output: Article

4 Citations (Scopus)

Simultaneous quantification of protein order and disorder

Sormanni, P., Piovesan, D., Heller, G. T., Bonomi, M., Kukic, P., Camilloni, C., Fuxreiter, M., Dosztányi, Z., Pappu, R. V., Babu, M. M., Longhi, S., Tompa, P., Dunker, A. K., Uversky, V. N., Tosatto, S. C. E. & Vendruscolo, M., márc. 22 2017, In : Nature Chemical Biology. 13, 4, p. 339-342 4 p.

Research output: Comment/debate

45 Citations (Scopus)
2016

A Derived Allosteric Switch Underlies the Evolution of Conditional Cooperativity between HOXA11 and FOXO1

Nnamani, M. C., Ganguly, S., Erkenbrack, E. M., Lynch, V. J., Mizoue, L. S., Tong, Y., Darling, H. L., Fuxreiter, M., Meiler, J. & Wagner, G. P., jún. 7 2016, In : Cell Reports. 15, 10, p. 2097-2108 12 p.

Research output: Article

12 Citations (Scopus)

Fuzzy regions in an intrinsically disordered protein impair protein-protein interactions

Gruet, A., Dosnon, M., Blocquel, D., Brunel, J., Gerlier, D., Das, R. K., Bonetti, D., Gianni, S., Fuxreiter, M., Longhi, S. & Bignon, C., febr. 1 2016, In : FEBS Journal. 283, 4, p. 576-594 19 p.

Research output: Article

20 Citations (Scopus)

The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules

Wu, H. & Fuxreiter, M., máj. 19 2016, In : Cell. 165, 5, p. 1055-1066 12 p.

Research output: Review article

140 Citations (Scopus)
2015

Erratum: Correction to disordered proteinaceous machines (Chemical Reviews (2014) 114:13 (6806-6843) DOI 10.0121/cr4007329)

Fuxreiter, M., Tóth-Petróczy, Á., Kraut, D. A., Matouschek, A., Lim, R. Y. H., Xue, B., Kurgan, L. & Uversky, V. N., ápr. 8 2015, In : Chemical reviews. 115, 7, 1 p.

Research output: Comment/debate

Fuzziness endows viral motif-mimicry

Duro, N., Miskei, M. & Fuxreiter, M., aug. 1 2015, In : Molecular BioSystems. 11, 10, p. 2821-2829 9 p.

Research output: Article

7 Citations (Scopus)

Fuzzy complexes: Specific binding without complete folding

Sharma, R., Raduly, Z., Miskei, M. & Fuxreiter, M., szept. 14 2015, In : FEBS letters. 589, 19, p. 2533-2542 10 p.

Research output: Review article

93 Citations (Scopus)
30 Citations (Scopus)
2014

Classification of intrinsically disordered regions and proteins

Van Der Lee, R., Buljan, M., Lang, B., Weatheritt, R. J., Daughdrill, G. W., Dunker, A. K., Fuxreiter, M., Gough, J., Gsponer, J., Jones, D. T., Kim, P. M., Kriwacki, R. W., Oldfield, C. J., Pappu, R. V., Tompa, P., Uversky, V. N., Wright, P. E. & Babu, M. M., júl. 9 2014, In : Chemical reviews. 114, 13, p. 6589-6631 43 p.

Research output: Review article

697 Citations (Scopus)
3 Citations (Scopus)

Disordered proteinaceous machines

Fuxreiter, M., Tóth-Petróczy, Á., Kraut, D. A., Matouschek, A. T., Lim, R. Y. H., Xue, B., Kurgan, L. & Uversky, V. N., júl. 9 2014, In : Chemical reviews. 114, 13, p. 6806-6843 38 p.

Research output: Review article

63 Citations (Scopus)

Dynamics: A key to protein function

Fuxreiter, M., jan. 1 2014, Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained Methods. CRC Press, p. 3-38 36 p.

Research output: Chapter

Intrinsically disordered segments affect protein half-life in the cell and during evolution

van der Lee, R., Lang, B., Kruse, K., Gsponer, J., de Groot, N. S., Huynen, M. A., Matouschek, A., Fuxreiter, M. & Babu, M. M., szept. 25 2014, In : Cell Reports. 8, 6, p. 1832-1844 13 p.

Research output: Article

84 Citations (Scopus)

The role of reorganization energy in rational enzyme design

Fuxreiter, M. & Mones, L., aug. 2014, In : Current Opinion in Chemical Biology. 21, p. 34-41 8 p.

Research output: Review article

12 Citations (Scopus)
2013

Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

Buljan, M., Chalancon, G., Dunker, A. K., Bateman, A., Balaji, S., Fuxreiter, M. & Babu, M. M., jún. 1 2013, In : Current Opinion in Structural Biology. 23, 3, p. 443-450 8 p.

Research output: Review article

100 Citations (Scopus)

Identification of a specific one amino acid change in recombinant human transglutaminase 2 that regulates its activity and calcium sensitivity

Kanchan, K., Ergülen, E., Király, R., Simon-Vecsei, Z., Fuxreiter, M. & Fésüs, L., nov. 1 2013, In : Biochemical Journal. 455, 3, p. 261-272 12 p.

Research output: Article

20 Citations (Scopus)
20 Citations (Scopus)
2012

Fuzziness: Linking regulation to protein dynamics

Fuxreiter, M., jan. 1 2012, In : Molecular BioSystems. 8, 1, p. 168-177 10 p.

Research output: Review article

108 Citations (Scopus)

Fuzzy complexes: A more stochastic view of protein function

Fuxreiter, M. & Tompa, P., ápr. 19 2012, Fuzziness: Structural Disorder in Protein Complexes. p. 1-14 14 p. (Advances in Experimental Medicine and Biology; vol. 725).

Research output: Chapter

131 Citations (Scopus)

Interactions via intrinsically disordered regions: What kind of motifs?

Pancsa, R. & Fuxreiter, M., jún. 1 2012, In : IUBMB life. 64, 6, p. 513-520 8 p.

Research output: Review article

50 Citations (Scopus)

Preface

Fuxreiter, M. & Tompa, P., ápr. 19 2012, Fuzziness: Structural Disorder in Protein Complexes. p. ix-xiii (Advances in Experimental Medicine and Biology; vol. 725).

Research output: Foreword/postscript

4 Citations (Scopus)

QM/MM simulation of liquid water with an adaptive quantum region

Bernstein, N., Várnai, C., Solt, I., Winfield, S. A., Payne, M. C., Simon, I., Fuxreiter, M. & Csányi, G., jan. 14 2012, In : Physical Chemistry Chemical Physics. 14, 2, p. 646-656 11 p.

Research output: Article

61 Citations (Scopus)

Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks

Buljan, M., Chalancon, G., Eustermann, S., Wagner, G. P., Fuxreiter, M., Bateman, A. & Babu, M. M., jún. 29 2012, In : Molecular Cell. 46, 6, p. 871-883 13 p.

Research output: Article

226 Citations (Scopus)
2011

Active site residue involvement in monoamine or diamine oxidation catalysed by pea seedling amine oxidase

Di Paolo, M. L., Lunelli, M., Fuxreiter, M., Rigo, A., Simon, I. & Scarpa, M., ápr. 1 2011, In : FEBS Journal. 278, 8, p. 1232-1243 12 p.

Research output: Article

4 Citations (Scopus)

Dynamic protein-DNA recognition: Beyond what can be seen

Fuxreiter, M., Simon, I. & Bondos, S., aug. 1 2011, In : Trends in Biochemical Sciences. 36, 8, p. 415-423 9 p.

Research output: Review article

104 Citations (Scopus)
2009

Close encounters of the third kind: Disordered domains and the interactions of proteins

Tompa, P., Fuxreiter, M., Oldfield, C. J., Simon, I., Dunker, A. K. & Uversky, V. N., ápr. 27 2009, In : BioEssays. 31, 3, p. 328-335 8 p.

Research output: Article

181 Citations (Scopus)
53 Citations (Scopus)

Evaluating boundary dependent errors in QM/MM simulations

Solt, I., Kulhánek, P., Simon, I., Winfield, S., Payne, M. C., Csányi, G. & Fuxreiter, M., ápr. 30 2009, In : Journal of Physical Chemistry B. 113, 17, p. 5728-5735 8 p.

Research output: Article

43 Citations (Scopus)
8 Citations (Scopus)

Intrinsically disordered proteins and their recognition functions

Uversky, V. N., Fuxreiter, M., Oldfield, C. J., Dunker, A. K. & Tompa, P., jan. 1 2009, Computational Protein-Protein Interactions. CRC Press, p. 223-252 30 p.

Research output: Chapter

1 Citation (Scopus)

On the Divalent Metal Ion Dependence of DNA Cleavage by Restriction Endonucleases of the EcoRI Family

Pingoud, V., Wende, W., Friedhoff, P., Reuter, M., Alves, J., Jeltsch, A., Mones, L., Fuxreiter, M. & Pingoud, A., okt. 16 2009, In : Journal of molecular biology. 393, 1, p. 140-160 21 p.

Research output: Article

43 Citations (Scopus)

The energy gap as a universal reaction coordinate for the simulation of chemical reactions

Mones, L., Kulhánek, P., Simon, I., Laio, A. & Fuxreiter, M., jún. 4 2009, In : Journal of Physical Chemistry B. 113, 22, p. 7867-7873 7 p.

Research output: Article

25 Citations (Scopus)
2008
625 Citations (Scopus)

Malleable machines in transcription regulation: The Mediator complex

Tóth-Petróczy, Á., Oldfield, C. J., Simon, I., Takagi, Y., Dunker, A. K., Uversky, V. N. & Fuxreiter, M., dec. 2008, In : PLoS computational biology. 4, 12, e1000243.

Research output: Article

78 Citations (Scopus)

Malleable machines take shape in eukaryotic transcriptional regulation

Fuxreiter, M., Tompa, P., Simon, I., Uversky, V. N., Hansen, J. C. & Asturias, F. J., dec. 2008, In : Nature Chemical Biology. 4, 12, p. 728-737 10 p.

Research output: Review article

145 Citations (Scopus)
2007

An EcoRI-RsrI chimeric restriction endonuclease retains parental sequence specificity

Chuluunbaatar, T., Ivanenko-Johnston, T., Fuxreiter, M., Meleshko, R., Raskó, T., Simon, I., Heitman, J. & Kiss, A., máj. 1 2007, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1774, 5, p. 583-594 12 p.

Research output: Article

3 Citations (Scopus)
20 Citations (Scopus)