M. Al-Khrasani

  • Hungary

  • 670 Citations
  • 16 h-Index
20012019

Research output per year

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Research Output

  • 670 Citations
  • 16 h-Index
  • 48 Article
  • 2 Review article

14-O-Methylmorphine: A Novel Selective Mu-Opioid Receptor Agonist with High Efficacy and Affinity

Zádor, F., Balogh, M., Váradi, A., Zádori, Z. S., Király, K., Szűcs, E., Varga, B., Lázár, B., Hosztafi, S., Riba, P., Benyhe, S., Fürst, S. & Al-Khrasani, M., nov. 5 2017, In : European Journal of Pharmacology. 814, p. 264-273 10 p.

Research output: Article

2 Citations (Scopus)
1 Citation (Scopus)

A new potent analgesic agent with reduced liability to produce morphine tolerance

Kiraly, K., Caputi, F. F., Hanuska, A., Kató, E., Balogh, M., Köles, L., Palmisano, M., Riba, P., Hosztafi, S., Romualdi, P., Candeletti, S., Ferdinandy, P., Fürst, S. & Al-Khrasani, M., aug. 1 2015, In : Brain Research Bulletin. 117, p. 32-38 7 p.

Research output: Article

10 Citations (Scopus)

A novel μ-opioid receptor ligand with high in vitro and in vivo agonist efficacy

Lackó, E., Váradi, A., Rapavi, R., Zádor, F., Riba, P., Benyhe, S., Borsodi, A., Hosztafi, S., Timár, J., Noszál, B., Fürst, S. & Al-Khrasani, M., jan. 1 2012, In : Current medicinal chemistry. 19, 27, p. 4699-4707 9 p.

Research output: Article

11 Citations (Scopus)
5 Citations (Scopus)

Biochemical and pharmacological characterization of three opioid-nociceptin hybrid peptide ligands reveals substantially differing modes of their actions

Erdei, A. I., Borbély, A., Magyar, A., Taricska, N., Perczel, A., Zsíros, O., Garab, G., Szűcs, E., Ötvös, F., Zádor, F., Balogh, M., Al-Khrasani, M. & Benyhe, S., jan. 2018, In : Peptides. 99, p. 205-216 12 p.

Research output: Article

1 Citation (Scopus)

Biochemical and pharmacological investigation of novel nociceptin/OFQ analogues and N/OFQ-RYYRIK hybrid peptides

Erdei, A. I., Borbély, A., Magyar, A., Szűcs, E., Ötvös, F., Gombos, D., Al-Khrasani, M., Stefanucci, A., Dimmito, M. P., Luisi, G., Mollica, A. & Benyhe, S., febr. 2019, In : Peptides. 112, p. 106-113 8 p.

Research output: Article

1 Citation (Scopus)
9 Citations (Scopus)
28 Citations (Scopus)
28 Citations (Scopus)
7 Citations (Scopus)

Dual Alpha2C/5HT1A Receptor Agonist Allyphenyline Induces Gastroprotection and Inhibits Fundic and Colonic Contractility

Zádori, Z. S., Fehér, Á., Tóth, V. E., Al-Khrasani, M., Köles, L., Sipos, S., Del Bello, F., Pigini, M. & Gyires, K., jún. 1 2016, In : Digestive Diseases and Sciences. 61, 6, p. 1512-1523 12 p.

Research output: Article

12 Citations (Scopus)

Effects of opioid agonist and antagonist in dams exposed to morphine during the perinatal period

Sobor, M., Timar, J., Riba, P., Friedmann, T., Király, K. P., Gyarmati, S., Al-Khrasani, M. & Fürst, S., jan. 15 2011, In : Brain Research Bulletin. 84, 1, p. 53-60 8 p.

Research output: Article

6 Citations (Scopus)

Efficacy-based perspective to overcome reduced opioid analgesia of advanced painful diabetic neuropathy in rats

Balogh, M., Zádor, F., Zádori, Z. S., Shaqura, M., Király, K., Mohammadzadeh, A., Varga, B., Lázár, B., Mousa, S. A., Hosztafi, S., Riba, P., Benyhe, S., Gyires, K., Schäfer, M., Fürst, S. & Al-Khrasani, M., jan. 1 2019, In : Frontiers in Pharmacology. 10, APR, 347.

Research output: Article

Open Access
2 Citations (Scopus)

Endomorphin-2 with a β-turn backbone constraint retains the potent μ-opioid receptor agonist properties

Tömböly, C., Ballet, S., Feytens, D., Köver, K. E., Borics, A., Lovas, S., Al-Khrasani, M., Fürst, Z., Tóth, G., Benyhe, S. & Tourwé, D., jan. 10 2008, In : Journal of Medicinal Chemistry. 51, 1, p. 173-177 5 p.

Research output: Article

33 Citations (Scopus)
17 Citations (Scopus)
5 Citations (Scopus)

Glycine transporter inhibitors: A new avenue for managing neuropathic pain

Al-Khrasani, M., Mohammadzadeh, A., Balogh, M., Király, K., Barsi, S., Hajnal, B., Köles, L., Zádori, Z. S. & Harsing, L. G., okt. 2019, In : Brain Research Bulletin. 152, p. 143-158 16 p.

Research output: Review article

1 Citation (Scopus)

Imidazoline versus alpha2-adrenoceptors in the control of gastric motility in mice

Zádori, Z. S., Fehér, Á., Al-Khrasani, M., Lackó, E., Tóth, V. E., Brancati, S. B., Hein, L., Mátyus, P. & Gyires, K., ápr. 5 2013, In : European Journal of Pharmacology. 705, 1-3, p. 61-67 7 p.

Research output: Article

8 Citations (Scopus)

Increase of intracellular Ca2+ by adenine and uracil nucleotides in human midbrain-derived neuronal progenitor cells

Rubini, P., Milosevic, J., Engelhardt, J., Al-Khrasani, M., Franke, H., Heinrich, A., Sperlagh, B., Schwarz, S. C., Schwarz, J., Nörenberg, W. & Illes, P., máj. 2009, In : Cell Calcium. 45, 5, p. 485-498 14 p.

Research output: Article

16 Citations (Scopus)
2 Citations (Scopus)
26 Citations (Scopus)

Membrane-bound glucocorticoid receptors on distinct nociceptive neurons as potential targets for pain control through rapid non-genomic effects

Shaqura, M., Li, X., Al-Khrasani, M., Shakibaei, M., Tafelski, S., Fürst, S., Beyer, A., Kawata, M., Schäfer, M. & Mousa, S. A., dec. 1 2016, In : Neuropharmacology. 111, p. 1-13 13 p.

Research output: Article

18 Citations (Scopus)
28 Citations (Scopus)

New insights into mechanisms of opioid inhibitory effects on capsaicin-induced TRPV1 activity during painful diabetic neuropathy

Shaqura, M., Khalefa, B. I., Shakibaei, M., Zöllner, C., Al-Khrasani, M., Fürst, S., Schäfer, M. & Mousa, S. A., okt. 2014, In : Neuropharmacology. 85, p. 142-150 9 p.

Research output: Article

12 Citations (Scopus)

New morphine analogs produce peripheral antinociception within a certain dose range of their systemic administration

Lackó, E., Riba, P., Giricz, Z., Váradi, A., Cornic, L., Balogh, M., Király, K., Cseko, K., Mousa, S. A., Hosztafi, S., Schäfer, M., Zádori, Z., Helyes, Z., Ferdinandy, P., Fürst, S. & Al-Khrasani, M., okt. 1 2016, In : Journal of Pharmacology and Experimental Therapeutics. 359, 1, p. 171-181 11 p.

Research output: Article

7 Citations (Scopus)

New opioid receptor antagonist: Naltrexone-14-O-sulfate synthesis and pharmacology

Zádor, F., Király, K., Váradi, A., Balogh, M., Fehér, Á., Kocsis, D., Erdei, A., Lackó, E., Zádori, Z., Hosztafi, S., Noszál, B., Riba, P., Benyhe, S., Fürst, S. & Al-Khrasani, M., jan. 1 2017, In : European Journal of Pharmacology. 809, p. 111-121 11 p.

Research output: Article

3 Citations (Scopus)

Nociceptin antagonism: Probing the receptor by N-acetyl oligopeptides

Kocsis, L., Orosz, G., Magyar, A., Al-Khrasani, M., Kató, E., Rónai, A. Z., Bes, B., Meunier, J. C., Gündüz, Ö., Tóth, G., Borsodi, A. & Benyhe, S., nov. 15 2004, In : Regulatory Peptides. 122, 3, p. 199-207 9 p.

Research output: Article

18 Citations (Scopus)

Novel approach to demonstrate high efficacy of μ opioids in the rat vas deferens: A simple model of predictive value

Riba, P., Friedmann, T., Király, K. P., Al-Khrasani, M., Sobor, M., Asim, M. F., Spetea, M., Schmidhammer, H. & Furst, S., jan. 15 2010, In : Brain Research Bulletin. 81, 1, p. 178-184 7 p.

Research output: Article

12 Citations (Scopus)

Partial and full agonism in endomorphin derivatives: Comparison by null and operational model

Rónai, A. Z., Al-Khrasani, M., Benyhe, S., Lengyel, I., Kocsis, L., Orosz, G., Tóth, G., Kató, E. & Tóthfalusi, L., jún. 1 2006, In : Peptides. 27, 6, p. 1507-1513 7 p.

Research output: Article

17 Citations (Scopus)
11 Citations (Scopus)
9 Citations (Scopus)

Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat

Fürst, S., Riba, P., Friedmann, T., Tímar, J., Al-Khrasani, M., Obara, I., Makuch, W., Spetea, M., Schütz, J., Przewlocki, R., Przewlocka, B. & Schmidhammer, H., febr. 1 2005, In : Journal of Pharmacology and Experimental Therapeutics. 312, 2, p. 609-618 10 p.

Research output: Article

57 Citations (Scopus)
10 Citations (Scopus)
30 Citations (Scopus)

Reduced number, G protein coupling, and antinociceptive efficacy of spinal mu-opioid receptors in diabetic rats are reversed by nerve growth factor

Shaqura, M., Khalefa, B. I., Shakibaei, M., Winkler, J., Al-Khrasani, M., Fürst, S., Mousa, S. A. & Schäfer, M., júl. 1 2013, In : Journal of Pain. 14, 7, p. 720-730 11 p.

Research output: Article

20 Citations (Scopus)
26 Citations (Scopus)

Side chain modifications change the binding and agonist properties of endomorphin 2

Lengyel, I., Biyashev, D., Tömböly, C., Tóth, G., Borsodi, A., Orosz, G., Kocsis, L., Al-Khrasani, M., Rónai, A. & Fürst, Z., jan. 1 2002, In : Biochemical and biophysical research communications. 290, 1, p. 153-161 9 p.

Research output: Article

38 Citations (Scopus)
1 Citation (Scopus)

Spinal interaction between the highly selective μ agonist DAMGO and several δ opioid receptor ligands in naive and morphine-tolerant mice

Szentirmay, A. K., Király, K. P., Lenkey, N., Lackó, E., Al-Khrasani, M., Friedmann, T., Timár, J., Gyarmati, S., Tóth, G., Fürst, S. & Riba, P., jan. 1 2013, In : Brain Research Bulletin. 90, 1, p. 66-71 6 p.

Research output: Article

9 Citations (Scopus)
48 Citations (Scopus)

Subsensitivity of P2X but not vanilloid 1 receptors in dorsal root ganglia of rats caused by cyclophosphamide cystitis

Borvendeg, S. J., Al-Khrasani, M., Rubini, P., Fischer, W., Allgaier, C., Wirkner, K., Himmel, H. M., Gillen, C. & Illes, P., aug. 1 2003, In : European Journal of Pharmacology. 474, 1, p. 71-75 5 p.

Research output: Article

9 Citations (Scopus)

Synthesis and pharmacological activities of 6-glycine substituted 14-phenylpropoxymorphinans, a novel class of opioids with high opioid receptor affinities and antinociceptive potencies

Spetea, M., Windisch, P., Guo, Y., Bileviciute-Ljungar, I., Schütz, J., Asim, M. F., Berzetei-Gurske, I. P., Riba, P., Kiraly, K., Fürst, S., Al-Khrasani, M. & Schmidhammer, H., febr. 24 2011, In : Journal of Medicinal Chemistry. 54, 4, p. 980-988 9 p.

Research output: Article

8 Citations (Scopus)

Synthesis of enzymatically resistant nociceptin-related peptides containing a carbamic acid residue

Ligeti, M., Bösze, S., Csámpai, A., Gündüz, Ö., Al-Khrasani, M., Rónai, A. Z., Medzihradszky-Schweiger, H., Benyhe, S., Borsodi, A., Hudecz, F. & Magyar, A., júl. 1 2006, In : Journal of Peptide Science. 12, 7, p. 481-490 10 p.

Research output: Article

3 Citations (Scopus)

The central versus peripheral antinociceptive effects of μ-opioid receptor agonists in the new model of rat visceral pain

Al-Khrasani, M., Lackó, E., Riba, P., Király, K., Sobor, M., Timár, J., Mousa, S., Schäfer, M. & Fürst, S., febr. 10 2012, In : Brain Research Bulletin. 87, 2-3, p. 238-243 6 p.

Research output: Article

18 Citations (Scopus)
12 Citations (Scopus)

The Peripheral Versus Central Antinociception of a Novel Opioid Agonist: Acute Inflammatory Pain in Rats

Balogh, M., Zádori, Z., Lázár, B., Karádi, D., László, S., Mousa, S. A., Hosztafi, S., Zádor, F., Riba, P., Schäfer, M., Fürst, S. & Al-Khrasani, M., máj. 3 2018, (Accepted/In press) In : Neurochemical Research. p. 1-8 8 p.

Research output: Article

5 Citations (Scopus)

Viselkedési vizsgálatok a gesztációs-laktációs ido{double acute}szakban morfn-kezelt patkányon

Melinda, S., Júlia, T., Pál, R., Király, K. P., Al-Khrasani, M., Zsuzsanna, G. & Zsuzsanna, F., dec. 1 2013, In : Neuropsychopharmacologia Hungarica. 15, 4, p. 239-251 13 p.

Research output: Article

3 Citations (Scopus)
7 Citations (Scopus)