• 716 Citations
  • 14 h-Index
1990 …2019
If you made any changes in Pure these will be visible here soon.

Research Output 1990 2019

  • 716 Citations
  • 14 h-Index
  • 35 Article
2019
3 Citations (Scopus)

Contribution of syndecans to cellular internalization and fibrillation of amyloid-β(1–42)

Letoha, T., Hudák, A., Kúsz, E., Pettkó-Szandtner, A., Domonkos, I., Jósvay, K., Hofmann-Apitius, M. & Szilák, L., dec. 1 2019, In : Scientific reports. 9, 1, 1393.

Research output: Article

Open Access
Syndecans
Amyloid
Syndecan-3
Syndecan-4
Heparan Sulfate Proteoglycans

Tumor-specific inhibitory action of decorin on different hepatoma cell lines

Horváth, Z., Reszegi, A., Szilák, L., Dankó, T., Kovalszky, I. & Baghy, K., okt. 1 2019, In : Cellular Signalling. 62, 109354.

Research output: Article

Decorin
Hepatocellular Carcinoma
Cell Line
Neoplasms
Catenins
2018
3 Citations (Scopus)

Drought tolerance of European barley (Hordeum vulgare L.) varieties

Schmidthoffer, I., Szilák, L., Molnár, P., Csontos, P. & Skribanek, A., jan. 1 2018, In : Agriculture. 64, 3, p. 137-142 6 p.

Research output: Article

drought tolerance
barley
Hordeum vulgare
tolerance
drought
1 Citation (Scopus)

Heparan sulfate proteoglycan (HSPG) can take part in cell division: inside and outside

Ughy, B., Schmidthoffer, I. & Szilák, L., jan. 1 2018, (Accepted/In press) In : Cellular and Molecular Life Sciences.

Research output: Article

Heparan Sulfate Proteoglycans
Cell Division
Cytokinesis
Syndecan-4
Actomyosin
1 Citation (Scopus)

Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria

Kóbori, T. O., Uzumaki, T., Kis, M., Kovács, L., Domonkos, I., Itoh, S., Krynická, V., Kuppusamy, S. G., Zakar, T., Dean, J., Szilák, L., Komenda, J., Gombos, Z. & Ughy, B., ápr. 1 2018, In : Journal of Plant Physiology. 223, p. 96-104 9 p.

Research output: Article

Phosphatidylglycerols
phosphatidylglycerols
Cyanobacteria
electron transfer
metabolism
6 Citations (Scopus)

Syndecan-1 inhibits early stages of liver fibrogenesis by interfering with TGFβ1 action and upregulating MMP14

Regos, E., Abdelfattah, H. H., Reszegi, A., Szilák, L., Werling, K., Szabó, G., Kiss, A., Schaff, Z., Kovalszky, I. & Baghy, K., jan. 1 2018, (Accepted/In press) In : Matrix Biology.

Research output: Article

Syndecan-1
Liver
Thrombospondin 1
Intercellular Signaling Peptides and Proteins
Up-Regulation
2 Citations (Scopus)

Syndecan-4 influences mammalian myoblast proliferation by modulating myostatin signalling and G1/S transition

Keller-Pinter, A., Szabo, K., Kocsis, T., Deák, F., Ocsovszki, I., Zvara, A., Puskás, L., Szilák, L. & Dux, L., szept. 1 2018, In : FEBS Letters. 592, 18, p. 3139-3151 13 p.

Research output: Article

Syndecan-4
Myostatin
Myoblasts
Muscle
Heparin Lyase
2017
4 Citations (Scopus)

The phosphomimetic mutation of syndecan-4 binds and inhibits Tiam1 modulating Rac1 activity in PDZ interaction–dependent manner

Keller-Pinter, A., Ughy, B., Domoki, M., Pettko-Szandtner, A., Letoha, T., Tóvári, J., Tímár, J. & Szilák, L., nov. 1 2017, In : PLoS One. 12, 11, e0187094.

Research output: Article

Syndecan-4
mutation
mutants
Mutation
proteoglycans
2013
12 Citations (Scopus)

Contribution of syndecans to lipoplex-mediated gene delivery

Letoha, T., Kolozsi, C., Ékes, C., Keller-Pintér, A., Kúsz, E., Szakonyi, G., Duda, E. & Szilák, L., 2013, In : European Journal of Pharmaceutical Sciences. 49, 4, p. 550-555 6 p.

Research output: Article

Syndecans
Liposomes
Syndecan-4
Genes
Protein Isoforms
3 Citations (Scopus)

What is the potential of syndecan-4-targeted novel delivery technologies?

Szilák, L., Letoha, T. & Ughy, B., dec. 2013, In : Therapeutic Delivery. 4, 12, p. 1479-1481 3 p.

Research output: Article

Syndecan-4
Technology
2011
34 Citations (Scopus)

Specific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migration

Zong, F., Fthenou, E., Mundt, F., Szatmári, T., Kovalszky, I., Szilák, L., Brodin, D., Tzanakakis, G., Hjerpe, A. & Dobra, K., 2011, In : PLoS One. 6, 6, e14816.

Research output: Article

Syndecan-1
Cell adhesion
cell movement
cell adhesion
Cell Adhesion
2010
73 Citations (Scopus)

Cell-penetrating peptide exploited syndecans

Letoha, T., Keller-Pintér, A., Kúsz, E., Kolozsi, C., Bozsó, Z., Tóth, G., Vízler, C., Oláh, Z. & Szilák, L., dec. 2010, In : BBA - Biomembranes. 1798, 12, p. 2258-2265 8 p.

Research output: Article

Syndecans
Cell-Penetrating Peptides
Syndecan-4
Protein Kinase C-alpha
Heparitin Sulfate
15 Citations (Scopus)

Effect of syndecan-1 overexpression on mesenchymal tumour cell proliferation with focus on different functional domains

Zong, F., Fthenou, E., Castro, J., Péterfia, B., Kovalszky, I., Szilák, L., Tzanakakis, G. & Dobra, K., febr. 2010, In : Cell Proliferation. 43, 1, p. 29-40 12 p.

Research output: Article

Syndecan-1
Cell Proliferation
Neoplasms
Proteoglycans
Confocal Microscopy
10 Citations (Scopus)

Syndecan-4 promotes cytokinesis in a phosphorylation-dependent manner

Keller-Pinter, A., Bottka, S., Tímár, J., Kulka, J., Katona, R., Dux, L., Deak, F. & Szilák, L., jún. 2010, In : Cellular and Molecular Life Sciences. 67, 11, p. 1881-1894 14 p.

Research output: Article

Syndecan-4
Cytokinesis
Phosphorylation
Cell-Matrix Junctions
Heparan Sulfate Proteoglycans
2009

A daganatos betegellátás innovatív fejlesztése genomikai módszerekkel. Beszámoló a nemzeti onkológiai konzorcium 2008. évi tevékenységé ro″l

Tímár, J., Kásler, M., Heringh, A., Soós, M., Mathiász, D., Romány, A., Józsa, A., Szilák, L., Forrai, T., Patthy, L. & Kovács, G., dec. 1 2009, In : Magyar Onkologia. 53, 4, p. 321-334 14 p.

Research output: Article

Genomics
Melanoma
Diagnostic Services
Patents
Molecular Pathology
41 Citations (Scopus)

Syndecan-1 and FGF-2, but not FGF receptor-1, share a common transport route and co-localize with heparanase in the nuclei of mesenchymal tumor cells

Zong, F., Fthenou, E., Wolmer, N., Hollósi, P., Kovalszky, I., Szilák, L., Mogler, C., Nilsonne, G., Tzanakakis, G. & Dobra, K., okt. 5 2009, In : PLoS One. 4, 10, e7346.

Research output: Article

Syndecan-1
Fibroblast Growth Factor 1
Fibroblast Growth Factor Receptors
Fibroblast Growth Factor 2
Tumors
2006
1 Citation (Scopus)

A daganatos betegellátás innovatív fejlesztése genomikai módszerekkel: Beszámoló a Nemzeti Onkológiai Konzorcium 2006. évi tevékenységé rol

Tímár, J., Kásler, M., Kátai, J., Soós, M., Mathiasz, D., Romány, A., Patthy, L., Kovács, G., Józsa, A., Szilák, L. & Forrai, T., 2006, In : Magyar Onkologia. 50, 4, p. 349-359 11 p.

Research output: Article

Molecular Pathology
Genomics
Hydroxymethyl and Formyl Transferases
Y-Linked Genes
Purinergic P2X7 Receptors
7 Citations (Scopus)

A syndecan-1 proteoglikán hatása a HT-1080 fibroszarkóma invazivitására

Péterfia, B., Hollósi, P., Szilák, L., Timár, F., Paku, S., Jeney, A. & Kovalszky, I., 2006, In : Magyar Onkologia. 50, 2, p. 115-120 6 p.

Research output: Article

Syndecan-1
Fibrosarcoma
Proteoglycans
Cell Line
Growth
19 Citations (Scopus)
Medicago sativa
cyclin-dependent kinase
Cyclin-Dependent Kinases
Protein-Serine-Threonine Kinases
Mitosis
2004
55 Citations (Scopus)
Tissue Preservation
Fixatives
Acetone
Paraffin
Formaldehyde
64 Citations (Scopus)

Interleukin-8 binds to syndecan-2 on human endothelial cells

Halden, Y., Rek, A., Atzenhofer, W., Szilák, L., Wabnig, A. & Kungl, A. J., jan. 15 2004, In : Biochemical Journal. 377, 2, p. 533-538 6 p.

Research output: Article

Syndecan-2
Endothelial cells
Interleukin-8
Endothelial Cells
Heparitin Sulfate
2002
4 Citations (Scopus)
osmotolerance
Triticum
Drought
Droughts
Genes
34 Citations (Scopus)
Osmoregulation
Drought
Droughts
osmotic stress
drought tolerance
1999

Structure of the DNA-binding domains from NFAT, FOS and JUN bound specifically to DNA

Chen, L., Glover, M., Hogan, P., Rao, A., Harrison, S. C., Szilák, L., Moll, J. R. & Vinson, C., szept. 1999, In : Chemtracts. 12, 10, p. 768-773 6 p.

Research output: Article

DNA
1997
38 Citations (Scopus)
Leucine Zippers
Phosphorylation
Serine
Basic-Leucine Zipper Transcription Factors
Dimers
116 Citations (Scopus)

Leucine is the most stabilizing aliphatic amino acid in the d position of a dimeric leucine zipper coiled coil

Moitra, J., Szilák, L., Krylov, D. & Vinson, C., okt. 14 1997, In : Biochemistry. 36, 41, p. 12567-12573 7 p.

Research output: Article

Leucine Zippers
Leucine
Fatty Acids
Amino Acids
Isoleucine
70 Citations (Scopus)

Phosphorylation destabilizes α-helices

Szilák, L., Moitra, J., Krylov, D. & Vinson, C., 1997, In : Nature Structural Biology. 4, 2, p. 112-114 3 p.

Research output: Article

Phosphorylation
Threonine
Basic-Leucine Zipper Transcription Factors
Leucine Zippers
Dimers
1995
3 Citations (Scopus)

Self-methylation of the M·BspRI methyltransferase

Szilák, L., Finta, C., Pátthy, A., Venetianer, P. & Kiss, A., máj. 19 1995, In : Gene. 157, 1-2, p. 105 1 p.

Research output: Article

Methyltransferases
Methylation
DNA
Methionine
1994
Methyltransferases
DNA Methylation
Nucleic Acids
Research
2 Citations (Scopus)

Self-methylation of BspRI DNA-methyltransferase

Szilák, L., Finta, C., Pátthy, A., Venetianer, P. & Kiss, A., okt. 25 1994, In : Nucleic Acids Research. 22, 21, p. 4552 1 p.

Research output: Article

Methylation
Methyltransferases
DNA Methylation
Assays
DNA
7 Citations (Scopus)

Self-methylation of BspRI DNA-methyltransferase

Szilák, L., Finta, C., Pátthy, A., Venetianer, P. & Kiss, A., aug. 11 1994, In : Nucleic Acids Research. 22, 15, p. 2876-2881 6 p.

Research output: Article

Methylation
Methyltransferases
DNA Methylation
Cysteine
DNA (Cytosine-5-)-Methyltransferase
1993
26 Citations (Scopus)

Kinetic characterization of the EcaI methyltransferase

Szilák, L., Dér, A., Deak, F. & Venetianer, P., 1993, In : European Journal of Biochemistry. 218, 2, p. 727-733 7 p.

Research output: Article

Methyltransferases
Kinetics
DNA
Methionine
Adenine
1992
8 Citations (Scopus)
Purification
S-Adenosylmethionine
DNA
Methyltransferases
sinefungin
1991
15 Citations (Scopus)

Complementation by detached parts of GGCC-specific DNA methyltransferases

Pósfai, G., Kim, S. C., Szilák, L., Kovács, A. & Venetianer, P., szept. 25 1991, In : Nucleic Acids Research. 19, 18, p. 4843-4847 5 p.

Research output: Article

Complementation
Fragment
DNA
Enzymes
Methyltransferases
1990
39 Citations (Scopus)
Cloning
Methyltransferases
Nucleotides
Amino Acids
Organism Cloning