• 14989 Citations
  • 50 h-Index
1991 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

Glucocorticoids counteract hypertrophic effects of myostatin inhibition in dystrophic muscle

Hammers, D. W., Hart, C. C., Patsalos, A., Matheny, M. K., Wright, L. A., Nagy, L. & Sweeney, H. L., jan. 1 2020, In : JCI Insight. 5, 1, e133276.

Research output: Article

Open Access
1 Citation (Scopus)

Intracardiac Fibrinolysis and Endothelium Activation Related to Atrial Fibrillation Ablation with Different Techniques

Hajas, O., Bagoly, Z., Tóth, N. K., Urbancsek, R., Kiss, A., Kovács, K. B., Sarkady, F., Nagy, A., Oláh, A. V., Nagy, L., Clemens, M., Csiba, L. & Csanádi, Z., jan. 1 2020, In : Cardiology Research and Practice. 2020, 1570483.

Research output: Article

Open Access

Simultaneous Mapping of Molecular Proximity and Comobility Reveals Agonist-Enhanced Dimerization and DNA Binding of Nuclear Receptors

Rehó, B., Lau, L., Mocsár, G., Müller, G., Fadel, L., Brázda, P., Nagy, L., Tóth, K. & Vámosi, G., jan. 21 2020, In : Analytical Chemistry. 92, 2, p. 2207-2215 9 p.

Research output: Article

2019

CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-β-producing macrophages and T cells

Moreira, T. G., Horta, L. S., Gomes-Santos, A. C., Oliveira, R. P., Queiroz, N. M. G. P., Mangani, D., Daniel, B., Vieira, A. T., Liu, S., Rodrigues, A. M., Gomes, D. A., Gabriely, G., Ferreira, E., Weiner, H. L., Rezende, R. M., Nagy, L. & Faria, A. M. C., jan. 1 2019, In : Mucosal Immunology. 12, 1, p. 188-199 12 p.

Research output: Article

3 Citations (Scopus)

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration

Giannakis, N., Sansbury, B. E., Patsalos, A., Hays, T. T., Riley, C. O., Han, X., Spite, M. & Nagy, L., máj. 1 2019, In : Nature Immunology. 20, 5, p. 626-636 11 p.

Research output: Article

14 Citations (Scopus)

Gene expression analysis of vascular pathophysiology related to anti-TNF treatment in rheumatoid arthritis

Póliska, S., Besenyei, T., Végh, E., Hamar, A., Pusztai, A., Váncsa, A., Bodnár, N., Szamosi, S., Csumita, M., Kerekes, G., Szabó, Z., Nagy, Z., Szucs, G., Szántó, S., Zahuczky, G., Nagy, L. & Szekanecz, Z., ápr. 15 2019, In : Arthritis Research and Therapy. 21, 1, 94.

Research output: Article

Open Access
6 Citations (Scopus)

Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis

Puchalska, P., Martin, S. E., Huang, X., Lengfeld, J. E., Daniel, B., Graham, M. J., Han, X., Nagy, L., Patti, G. J. & Crawford, P. A., febr. 5 2019, In : Cell Metabolism. 29, 2, p. 383-398.e7

Research output: Article

10 Citations (Scopus)

Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties

Smith, D. G., Martinelli, R., Besra, G. S., Illarionov, P. A., Szatmari, I., Brazda, P., Allen, M. A., Xu, W., Wang, X., Nagy, L., Dowell, R. D., Rook, G. A. W., Rosa Brunet, L. & Lowry, C. A., máj. 1 2019, In : Psychopharmacology. 236, 5, p. 1653-1670 18 p.

Research output: Article

5 Citations (Scopus)

Labelled regulatory elements are pervasive features of the macrophage genome and are dynamically utilized by classical and alternative polarization signals

Horvath, A., Daniel, B., Szeles, L., Cuaranta-Monroy, I., Czimmerer, Z., Ozgyin, L., Steiner, L., Kiss, M., Simandi, Z., Poliska, S., Giannakis, N., Raineri, E., Gut, I. G., Nagy, B. & Nagy, L., jan. 1 2019, In : Nucleic acids research. 47, 6, p. 2778-2792 15 p.

Research output: Article

Open Access
1 Citation (Scopus)

Signal integration of IFN-I and IFN-II with TLR4 involves sequential recruitment of STAT1-Complexes and NFκB to enhance pro-inflammatory transcription

Piaszyk-Borychowska, A., Széles, L., Csermely, A., Chiang, H. C., Wesoły, J., Lee, C. K., Nagy, L. & Bluyssen, H. A. R., 2019, In : Frontiers in immunology. 10, JUN, 1253.

Research output: Article

Open Access
3 Citations (Scopus)

The BACH1-HMOX1 regulatory axis is indispensable for proper macrophage subtype specification and skeletal muscle regeneration

Patsalos, A., Tzerpos, P., Halasz, L., Nagy, G., Pap, A., Giannakis, N., Lyroni, K., Koliaraki, V., Pintye, E., Dezso, B., Kollias, G., Spilianakis, C. G. & Nagy, L., szept. 15 2019, In : Journal of Immunology. 203, 6, p. 1532-1547 16 p.

Research output: Article

4 Citations (Scopus)
2018

A pharmacogenetic approach to the treatment of patients with PPARG mutations

Agostini, M., Schoenmakers, E., Beig, J., Fairall, L., Szatmari, I., Rajanayagam, O., Muskett, F. W., Adams, C., Marais, A. D., O’Rahilly, S., Semple, R. K., Nagy, L., Majithia, A. R., Schwabe, J. W. R., Blom, D. J., Murphy, R., Chatterjee, K. & Savage, D. B., jún. 1 2018, In : Diabetes. 67, 6, p. 1086-1092 7 p.

Research output: Article

10 Citations (Scopus)

Arginine methyltransferase PRMT8 provides cellular stress tolerance in aging motoneurons

Simandi, Z., Pajer, K., Karolyi, K., Sieler, T., Jiang, L. L., Kolostyak, Z., Sari, Z., Fekecs, Z., Pap, A., Patsalos, A., Contreras, G. A., Reho, B., Papp, Z., Guo, X., Horvath, A., Kiss, G., Keresztessy, Z., Vámosi, G., Hickman, J., Xu, H. & 5 others, Dormann, D., Hortobagyi, T., Antal, M., Nógrádi, A. & Nagy, L., aug. 29 2018, In : Journal of Neuroscience. 38, 35, p. 7683-7700 18 p.

Research output: Article

7 Citations (Scopus)

Consumption of conjugated linoleic acid (CLA)-supplemented diet during colitis development ameliorates gut inflammation without causing steatosis in mice

Moreira, T. G., Gomes-Santos, A. C., Horta, L. S., Goncalves, M. C., Santiago, A. F., Lauar, J. G., dos Reis, D. S., Castro-Junior, A. B., Lemos, L., Guimarães, M., Aguilar, E. C., Pap, A., Amaral, J. F., Alvarez-Leite, J. I., Cara, D. C., Rezende, R. M., Nagy, L., Faria, A. M. C. & Maioli, T. U., júl. 2018, In : Journal of Nutritional Biochemistry. 57, p. 238-245 8 p.

Research output: Article

1 Citation (Scopus)

Dynamic transcriptional control of macrophage miRNA signature via inflammation responsive enhancers revealed using a combination of next generation sequencing-based approaches

Czimmerer, Z., Horvath, A., Daniel, B., Nagy, G., Cuaranta-Monroy, I., Kiss, M., Kolostyak, Z., Poliska, S., Steiner, L., Giannakis, N., Varga, T. & Nagy, L., jan. 2018, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1861, 1, p. 14-28 15 p.

Research output: Article

5 Citations (Scopus)

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages

Czimmerer, Z., Nagy, Z. S., Nagy, G., Horvath, A., Silye-Cseh, T., Kriston, A., Jonas, D., Sauer, S., Steiner, L., Daniel, B., Deleuze, J. F. & Nagy, L., aug. 15 2018, In : Molecular and Cellular Endocrinology. 471, p. 63-74 12 p.

Research output: Article

3 Citations (Scopus)

In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury

Patsalos, A., Simandi, Z., Hays, T. T., Peloquin, M., Hajian, M., Restrepo, I., Coen, P. M., Russell, A. J. & Nagy, L., okt. 2018, In : Aging cell. 17, 5, e12815.

Research output: Article

3 Citations (Scopus)

Liver X receptor nuclear receptors are transcriptional regulators of dendritic cell chemotaxis

Beceiro, S., Pap, A., Czimmerer, Z., Sallam, T., Guillén, J. A., Gallardo, G., Hong, C., A-Gonzalez, N., Tabraue, C., Diaz, M., Lopez, F., Matalong, J., Valledor, A. F., Dominguez, P., Ardavin, C., Delgado-Martin, C., Partida-Sanchez, S., Rodriguez-Fernandez, J. L., Nagy, L., Tontono, P. & 1 others, Castrillo, A., máj. 1 2018, In : Molecular and cellular biology. 38, 10, e00534.

Research output: Article

8 Citations (Scopus)

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification

Simandi, Z., Horvath, A., Cuaranta-Monroy, I., Sauer, S., Deleuze, J. F. & Nagy, L., aug. 15 2018, In : Molecular and Cellular Endocrinology. 471, p. 51-62 12 p.

Research output: Article

4 Citations (Scopus)

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages

Daniel, B., Nagy, G., Horvath, A., Czimmerer, Z., Cuaranta-Monroy, I., Poliska, S., Hays, T. T., Sauer, S., Francois-Deleuze, J. & Nagy, L., máj. 2018, In : Nucleic acids research. 46, 9, p. 4425-4439 15 p.

Research output: Article

Open Access
7 Citations (Scopus)

The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory

Daniel, B., Nagy, G., Czimmerer, Z., Horvath, A., Hammers, D. W., Cuaranta-Monroy, I., Poliska, S., Tzerpos, P., Kolostyak, Z., Hays, T. T., Patsalos, A., Houtman, R., Sauer, S., Francois-Deleuze, J., Rastinejad, F., Balint, B. L., Sweeney, H. L. & Nagy, L., okt. 16 2018, In : Immunity. 49, 4, p. 615-626.e6

Research output: Article

19 Citations (Scopus)

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

Czimmerer, Z., Daniel, B., Horvath, A., Rückerl, D., Nagy, G., Kiss, M., Peloquin, M., Budai, M. M., Cuaranta-Monroy, I., Simandi, Z., Steiner, L., Nagy, B., Poliska, S., Banko, C., Bacso, Z., Schulman, I. G., Sauer, S., Deleuze, J. F., Allen, J. E., Benko, S. & 1 others, Nagy, L., jan. 16 2018, In : Immunity. 48, 1, p. 75-90.e6

Research output: Article

43 Citations (Scopus)

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

Sallam, T., Jones, M., Thomas, B. J., Wu, X., Gilliland, T., Qian, K., Eskin, A., Casero, D., Zhang, Z., Sandhu, J., Salisbury, D., Rajbhandari, P., Civelek, M., Hong, C., Ito, A., Liu, X., Daniel, B., Lusis, A. J., Whitelegge, J., Nagy, L. & 3 others, Castrillo, A., Smale, S. & Tontonoz, P., márc. 1 2018, In : Nature medicine. 24, 3, p. 304-312 9 p.

Research output: Article

63 Citations (Scopus)
2017

A szkizofrénia multilókusz genetikai vizsgálata az idegfejlödés és az immunrendszer zavarának oki szerepére utal(hat)

Pulay, A. J., Koller, J., Nagy, L., Molnár, M. J. & Réthelyi, J., márc. 30 2017, In : Ideggyogyaszati Szemle. 70, 3-4, p. 115-126 12 p.

Research output: Article

In situ macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury

Patsalos, A., Pap, A., Varga, T., Trencsenyi, G., Contreras, G. A., Garai, I., Papp, Z., Dezso, B., Pintye, E. & Nagy, L., szept. 1 2017, In : Journal of Physiology. 595, 17, p. 5815-5842 28 p.

Research output: Article

15 Citations (Scopus)

Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein

Tarapcsák, S., Szalóki, G., Telbisz, Á., Gyöngy, Z., Matúz, K., Csosz, É., Nagy, P., Holb, I. J., Rühl, R., Nagy, L., Szabó, G. & Goda, K., febr. 1 2017, In : Scientific reports. 7, 41376.

Research output: Article

9 Citations (Scopus)

Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function

Bermudez, B., Dahl, T. B., Medina, I., Groeneweg, M., Holm, S., Montserrat-De La Paz, S., Rousch, M., Otten, J., Herias, V., Varela, L. M., Ranheim, T., Yndestad, A., Ortega-Gomez, A., Abia, R., Nagy, L., Aukrust, P., Muriana, F. J. G., Halvorsen, B. & Biessen, E. A. L., jún. 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 6, p. 1157-1167 11 p.

Research output: Article

12 Citations (Scopus)

MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans

Gal, A., Balicza, P., Weaver, D., Naghdi, S., Joseph, S. K., Várnai, P., Gyuris, T., Horváth, A., Nagy, L., Seifert, E. L., Molnar, M. J. & Hajnóczky, G., júl. 2017, In : EMBO Molecular Medicine. 9, 7, p. 967-984 18 p.

Research output: Article

19 Citations (Scopus)

Nucleosome stability measured in situ by automated quantitative imaging

Imre, L., Simándi, Z., Horváth, A., Fenyofalvi, G., Nánási, P., Niaki, E. F., Hegedüs, É., Bacsó, Z., Weyemi, U., Mauser, R., Ausio, J., Jeltsch, A., Bonner, W., Nagy, L., Kimura, H. & Szabó, G., dec. 1 2017, In : Scientific reports. 7, 1, 12734.

Research output: Article

8 Citations (Scopus)

Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism

Kiss, M., Czimmerer, Z., Nagy, G., Bieniasz-Krzywiec, P., Ehling, M., Pap, A., Poliska, S., Boto, P., Tzerpos, P., Horvath, A., Kolostyak, Z., Daniel, B., Szatmari, I., Mazzone, M. & Nagy, L., okt. 3 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 40, p. 10725-10730 6 p.

Research output: Article

7 Citations (Scopus)

Titin isoforms are increasingly protected against oxidative modifications in developing rat cardiomyocytes

Bódi, B., Tóth, E. P., Nagy, L., Tóth, A., Mártha, L., Kovács, Á., Balla, G., Kovács, T. & Papp, Z., dec. 2017, In : Free Radical Biology and Medicine. 113, p. 224-235 12 p.

Research output: Article

3 Citations (Scopus)
2016

Decreased peroxisome proliferator-activated receptor γ level and signalling in sebaceous glands of patients with acne vulgaris

Dozsa, A., Mihaly, J., Dezső, B., Csizmadia, E., Keresztessy, T., Marko, L., Rühl, R., Remenyik, E. & Nagy, L., júl. 1 2016, In : Clinical and Experimental Dermatology. 41, 5, p. 547-551 5 p.

Research output: Article

10 Citations (Scopus)

Highly dynamic transcriptional signature of distinct macrophage subsets during sterile inflammation, resolution, and tissue repair

Varga, T., Mounier, R., Horvath, A., Cuvellier, S., Dumont, F., Poliska, S., Ardjoune, H., Juban, G., Nagy, L. & Chazaud, B., jún. 1 2016, In : Journal of Immunology. 196, 11, p. 4771-4782 12 p.

Research output: Article

57 Citations (Scopus)

Macrophage PPARγ, a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration

Varga, T., Mounier, R., Patsalos, A., Gogolák, P., Peloquin, M., Horvath, A., Pap, A., Daniel, B., Nagy, G., Pintye, E., Poliska, S., Cuvellier, S., Ben Larbi, S., Sansbury, B. E., Spite, M., Brown, C. W., Chazaud, B. & Nagy, L., nov. 15 2016, In : Immunity. 45, 5, p. 1038-1051 14 p.

Research output: Article

38 Citations (Scopus)

Motif oriented high-resolution analysis of ChIP-seq data reveals the topological order of CTCF and cohesin proteins on DNA

Nagy, G., Czipa, E., Steiner, L., Nagy, T., Pongor, S., Nagy, L. & Barta, E., aug. 15 2016, In : BMC genomics. 17, 1, 637.

Research output: Article

14 Citations (Scopus)

OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation

Simandi, Z., Horvath, A., Wright, L. C., Cuaranta-Monroy, I., De Luca, I., Karolyi, K., Sauer, S., Deleuze, J. F., Gudas, L. J., Cowley, S. M. & Nagy, L., aug. 18 2016, In : Molecular Cell. 63, 4, p. 647-661 15 p.

Research output: Article

30 Citations (Scopus)

ORM-3819 promotes cardiac contractility through Ca2+ sensitization in combination with selective PDE III inhibition, a novel approach to inotropy

Nagy, L., Pollesello, P., Haikala, H., Végh, Á., Sorsa, T., Levijoki, J., Szilágyi, S., Édes, I., Tóth, A., Papp, Z. & Papp, J. G., márc. 15 2016, In : European Journal of Pharmacology. 775, p. 120-129 10 p.

Research output: Article

1 Citation (Scopus)
3 Citations (Scopus)

The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p

Czimmerer, Z., Varga, T., Kiss, M., Vázquez, C. O., Doan-Xuan, Q. M., Rückerl, D., Tattikota, S. G., Yan, X., Nagy, Z. S., Daniel, B., Poliska, S., Horvath, A., Nagy, G., Varallyay, E., Poy, M. N., Allen, J. E., Bacso, Z., Abreu-Goodger, C. & Nagy, L., máj. 31 2016, In : Genome Medicine. 8, 1, 63.

Research output: Article

22 Citations (Scopus)
2015

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

Rühl, R., Krzyżosiak, A., Niewiadomska-Cimicka, A., Rochel, N., Szeles, L., Vaz, B., Wietrzych-Schindler, M., Álvarez, S., Szklenar, M., Nagy, L., de Lera, A. R. & Krężel, W., júl. 1 2015, In : PLoS genetics. 11, 6, e1005213.

Research output: Article

51 Citations (Scopus)

Combination of IgG N-glycomics and corresponding transcriptomics data to identify anti-TNF-α treatment responders in inflammatory diseases

Váradi, C., Holló, Z., Póliska, S., Nagy, L., Szekanecz, Z., Váncsa, A., Palatka, K. & Guttman, A., jún. 1 2015, In : ELECTROPHORESIS. 36, 11-12, p. 1330-1335 6 p.

Research output: Article

5 Citations (Scopus)

Erratum: PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors [Cardiovasc Diabetol 13, (2014), 150]

Kotlinowski, J., Grochot-Przeczek, A., Taha, H., Kozakowska, M., Pilecki, B., Skrzypek, K., Zimoch, J., Bartelik, A., Derlacz, R., Horrevoets, A. J., Pap, A., Nagy, L., Dulak, J. & Jozkowicz, A., máj. 29 2015, In : Cardiovascular diabetology. 14, 1, 65.

Research output: Article

8 Citations (Scopus)
7 Citations (Scopus)

PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology

Simandi, Z., Czipa, E., Horvath, A., Koszeghy, A., Bordas, C., Põliska, S., Juhász, I., Imre, L., Szabõ, G., Dezso, B., Barta, E., Sauer, S., Karolyi, K., Kovacs, I., Hutõczki, G., Bognár, L., Klekner, Á., Szucs, P., Bálint, B. L. & Nagy, L., márc. 1 2015, In : Stem Cells. 33, 3, p. 726-741 16 p.

Research output: Article

25 Citations (Scopus)
35 Citations (Scopus)
2014

Highly efficient differentiation of embryonic stem cells into adipocytes by ascorbic acid

Cuaranta-Monroy, I., Simandi, Z., Kolostyak, Z., Doan-Xuan, Q. M., Poliska, S., Horvath, A., Nagy, G., Bacso, Z. & Nagy, L., júl. 2014, In : Stem Cell Research. 13, 1, p. 88-97 10 p.

Research output: Article

23 Citations (Scopus)
13 Citations (Scopus)

Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging

Brazda, P., Krieger, J., Daniel, B., Jonas, D., Szekeres, T., Langowski, J., Tóth, K., Nagy, L. & Vámosi, G., ápr. 2014, In : Molecular and cellular biology. 34, 7, p. 1234-1245 12 p.

Research output: Article

22 Citations (Scopus)