• 5324 Citations
  • 27 h-Index
1981 …2019

Research output per year

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Research Output

  • 5324 Citations
  • 27 h-Index
  • 67 Article
  • 8 Review article
  • 2 Comment/debate
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Article
Article

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis

Schätzl, H. M., Laszlo, L., Holtzman, D. M., Tatzelt, J., Dearmond, S. J., Weiner, R. I., Mobley, W. C. & Prusiner, S. B., nov. 1997, In : Journal of Virology. 71, 11, p. 8821-8831 11 p.

Research output: Article

Open Access
228 Citations (Scopus)

Alterations of NADPH:protochlorophyllide oxidoreductase quantity and lipid composition in etiolated barley seedlings infected by Barley stripe mosaic virus (BSMV)

Harsányi, A., Ryberg, M., Andersson, M. X., Bóka, K., László, L., Botond, G., Böddi, B. & Gáborjányi, R., okt. 26 2006, In : Molecular Plant Pathology. 7, 6, p. 533-541 9 p.

Research output: Article

5 Citations (Scopus)

A peculiar constellation of tau pathology defines a subset of dementia in the elderly

Kovacs, G. G., Molnár, K., László, L., Ströbel, T., Botond, G., Hönigschnabl, S., Reiner-Concin, A., Palkovits, M., Fischer, P. & Budka, H., aug. 1 2011, In : Acta neuropathologica. 122, 2, p. 205-222 18 p.

Research output: Article

56 Citations (Scopus)

A role for lysosomes in scrapie pathogenesis

Kenward, N., Laszlo, L., Landon, M., Fergusson, J., Lowe, J., McDermott, H., Hope, J., Brown, J. & Mayer, R. J., jan. 1 1992, In : Biochemical Society transactions. 20, 3, p. 265S

Research output: Article

4 Citations (Scopus)

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

Taraboulos, A., Scott, M., Semenov, A., Avraham, D., Laszlo, L. & Prusiner, S. B., ápr. 1995, In : Journal of Cell Biology. 129, 1, p. 121-132 12 p.

Research output: Article

489 Citations (Scopus)

Clinicopathological phenotype of codon 129 valine homozygote sporadic Creutzfeldt-Jakob disease

Kovacs, G. G., Head, M. W., Bunn, T., Laszlo, L., Will, R. G. & Ironside, J. W., okt. 30 2000, In : Neuropathology and Applied Neurobiology. 26, 5, p. 463-472 10 p.

Research output: Article

35 Citations (Scopus)

Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

Chandrasekaran, A., Avci, H. X., Ochalek, A., Rösingh, L. N., Molnár, K., László, L., Bellák, T., Téglási, A., Pesti, K., Mike, A., Phanthong, P., Bíró, O., Hall, V., Kitiyanant, N., Krause, K. H., Kobolák, J. & Dinnyés, A., dec. 1 2017, In : Stem Cell Research. 25, p. 139-151 13 p.

Research output: Article

20 Citations (Scopus)

Cytotoxic effect of alcohol-withdrawal on primary cultures of cortical neurones

Nagy, J., Müller, F. & László, L., jan. 1 2001, In : Drug and Alcohol Dependence. 61, 2, p. 155-162 8 p.

Research output: Article

26 Citations (Scopus)
25 Citations (Scopus)
Open Access
2 Citations (Scopus)

Emberi prionbetegségek: magyarországi tapasztalatok.

Kovács, G. G., Bakos, A., Mitrova, E., Minárovits, J., László, L. & Majtényi, K., nov. 30 2007, In : Ideggyógyászati szemle. 60, 11-12, p. 447-452 6 p.

Research output: Article

8 Citations (Scopus)

Endosome-lysosomes, ubiquitin and neurodegeneration

Mayer, R. J., Tipler, C., Arnold, J., Laszlo, L., Al-Khedhairy, A., Lowe, J. & Landon, M., dec. 1 1996, In : Advances in experimental medicine and biology. 389, p. 261-269 9 p.

Research output: Article

35 Citations (Scopus)

Endosome-lysosomes and neurodegeneration

Mayer, R. J., Tipler, C., Laszlo, L., Arnold, J., Lowe, J. & Landon, M., 1994, In : Biomedicine and Pharmacotherapy. 48, 7, p. 282-286 5 p.

Research output: Article

9 Citations (Scopus)

Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7

Sukseree, S., László, L., Gruber, F., Bergmann, S., Narzt, M. S., Nagelreiter, I. M., Höftberger, R., Molnár, K., Rauter, G., Birngruber, T., Larue, L., Kovacs, G. G., Tschachler, E. & Eckhart, L., nov. 1 2018, In : Molecular Neurobiology. 55, 11, p. 8425-8437 13 p.

Research output: Article

3 Citations (Scopus)

Genetic Creutzfeldt-Jakob disease associated with the E200K mutation: Characterization of a complex proteinopathy

Kovacs, G. G., Seguin, J., Quadrio, I., Höftberger, R., Kapás, I., Streichenberger, N., Biacabe, A. G., Meyronet, D., Sciot, R., Vandenberghe, R., Majtenyi, K., László, L., Ströbel, T., Budka, H. & Perret-Liaudet, A., jan. 1 2011, In : Acta neuropathologica. 121, 1, p. 39-57 19 p.

Research output: Article

71 Citations (Scopus)

Grapefruit seed extract inhibits the formation of amyloid-like fibrils by trypsin in aqueous ethanol

Kasi, P. B., Borics, A., Varga, M., Endre, G., Molnár, K., László, L. & Kotormán, M., jan. 1 2018, In : Natural Product Communications. 13, 11, p. 1437-1440 4 p.

Research output: Article

2 Citations (Scopus)

Immunochemical demonstration of ubiquitin conjugates in fibroblasts treated with cysteine proteinase inhibitors

Doherty, F. J., Osborn, N. U., Wassell, J. A., Laszlo, L. & Mayer, R. J., jan. 1 1989, In : Biochemical Society transactions. 17, 1, p. 171-172 2 p.

Research output: Article

4 Citations (Scopus)

Immunogold localisation of ubiquitin-protein conjugates in primary (azurophilic) granules of polymorphonuclear neutrophils

László, L., Doherty, F. J., Watson, A., Self, T., Landon, M., Lowe, J. & Mayer, R. J., febr. 25 1991, In : FEBS letters. 279, 2, p. 175-178 4 p.

Research output: Article

31 Citations (Scopus)
12 Citations (Scopus)

Immunohistochemistry for the prion protein: Comparison of different monoclonal antibodies in human prion disease subtypes

Kovács, G. G., Head, M. W., Hegyi, I., Bunn, T. J., Flicker, H., Hainfellner, J. A., McCardle, L., László, L., Jarius, C., Ironside, J. W. & Budka, H., 2002, In : Brain Pathology. 12, 1, p. 1-11 11 p.

Research output: Article

91 Citations (Scopus)

Immunoreactivity to ubiquitin—protein conjugates is present early in the disease process in the brains of scrapie‐infected mice

Lowe, J., Fergusson, J., Kenward, N., Laszlo, L., Landon, M., Farquhar, C., Brown, J., Hope, J. & Mayer, R. J., okt. 1992, In : The Journal of Pathology. 168, 2, p. 169-177 9 p.

Research output: Article

35 Citations (Scopus)

Increased incidence of genetic human prion disease in Hungary

Kovács, G. G., László, L., Bakos, A., Minárovits, J., Bishop, M. T., Ströbel, T., Vajna, B., Mitrova, E. & Majtényi, K., nov. 2005, In : Neurology. 65, 10, p. 1666-1669 4 p.

Research output: Article

15 Citations (Scopus)

Increased neuronal Rab5 immunoreactive endosomes do not colocalize with TDP-43 in motor neuron disease

Matej, R., Botond, G., László, L., Kopitar-Jerala, N., Rusina, R., Budka, H. & Kovacs, G. G., szept. 1 2010, In : Experimental Neurology. 225, 1, p. 133-139 7 p.

Research output: Article

9 Citations (Scopus)
30 Citations (Scopus)

Inherited prion disease with A117V mutation of the prion protein gene: A novel Hungarian family

Kovács, G. G., Ertsey, C., Majtényi, C., Jelencsik, I., László, L., Flicker, H., Strain, L., Szirmai, I. & Budka, H., jún. 1 2001, In : Journal of Neurology Neurosurgery and Psychiatry. 70, 6, p. 802-805 4 p.

Research output: Article

16 Citations (Scopus)
8 Citations (Scopus)

Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread

Kovacs, G. G., Breydo, L., Green, R., Kis, V., Puska, G., Lorincz, P., Perju-Dumbrava, L., Giera, R., Pirker, W., Lutz, M., Lachmann, I., Budka, H., Uversky, V. N., Molnár, K. & László, L., szept. 2014, In : Neurobiology of Disease. 69, p. 76-92 17 p.

Research output: Article

71 Citations (Scopus)
13 Citations (Scopus)

Is there a common intracellular bioreactor in which amyloid formation is initiated in neurodegenerative diseases?

Mayer, R. J., Landon, M., Lowe, J., Tipler, C., Arnold, J. & Laszlo, L., jan. 1 1994, In : Biochemical Society transactions. 22, 1, p. 151-155 5 p.

Research output: Article

Lysosomal response in relation to α-synuclein pathology differs between Parkinson's disease and multiple system atrophy

Puska, G., Lutz, M. I., Molnar, K., Regelsberger, G., Ricken, G., Pirker, W., László, L. & Kovacs, G. G., jún. 1 2018, In : Neurobiology of Disease. 114, p. 140-152 13 p.

Research output: Article

5 Citations (Scopus)

Lysosomes as key organelles in the pathogenesis of prion encephalopathies

Laszlo, L., Lowe, J., Self, T., Kenward, N., Landon, M., McBride, T., Farquhar, C., McConnell, I., Brown, J., Hope, J. & Mayer, R. J., ápr. 1992, In : The Journal of Pathology. 166, 4, p. 333-341 9 p.

Research output: Article

144 Citations (Scopus)

MAPT S305I mutation: Implications for argyrophilic grain disease

Kovacs, G. G., Pittman, A., Revesz, T., Luk, C., Lees, A., Kiss, E., Tariska, P., Laszlo, L., Molnár, K., Molnar, M. J., Tolnay, M. & de Silva, R., júl. 1 2008, In : Acta neuropathologica. 116, 1, p. 103-118 16 p.

Research output: Article

37 Citations (Scopus)

Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells

Kobolák, J., Molnár, K., Varga, E., Bock, I., Jezsó, B., Téglási, A., Zhou, S., Lo Giudice, M., Hoogeveen-Westerveld, M., Pijnappel, WWM. P., Phanthong, P., Varga, N., Kitiyanant, N., Freude, K., Nakanishi, H., László, L., Hyttel, P. & Dinnyés, A., júl. 15 2019, In : Experimental Cell Research. 380, 2, p. 216-233 18 p.

Research output: Article

Open Access
5 Citations (Scopus)
25 Citations (Scopus)

Mouse in red: Red fluorescent protein expression in mouse ES cells, embryos, and adult animals

Vintersten, K., Monetti, C., Gertsenstein, M., Zhang, P., Laszlo, L., Biechele, S. & Nagy, A., dec. 1 2004, In : Genesis. 40, 4, p. 241-246 6 p.

Research output: Article

223 Citations (Scopus)

Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

Kovács, G. G., László, L., Kovács, J., Jensen, P. H., Lindersson, E., Botond, G., Molnár, T., Perczel, A., Hudecz, F., Mezo, G., Erdei, A., Tirián, L., Lehotzky, A., Gelpi, E., Budka, H. & Ovádi, J., nov. 1 2004, In : Neurobiology of Disease. 17, 2, p. 155-162 8 p.

Research output: Article

100 Citations (Scopus)

Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation

Ochalek, A., Mihalik, B., Avci, H. X., Chandrasekaran, A., Téglási, A., Bock, I., Giudice, M. L., Táncos, Z., Molnár, K., László, L., Nielsen, J. E., Holst, B., Freude, K., Hyttel, P., Kobolák, J. & Dinnyés, A., dec. 1 2017, In : Alzheimer's Research and Therapy. 9, 1, 90.

Research output: Article

48 Citations (Scopus)

Novel crystalloid oligodendrogliopathy in hereditary spastic paraplegia

Woehrer, A., Laszlo, L., Finsterer, J., Stöllberger, C., Furtner, J., Rinner, W., Molnar, K., Budka, H. & Kovacs, G. G., okt. 1 2012, In : Acta neuropathologica. 124, 4, p. 583-591 9 p.

Research output: Article

4 Citations (Scopus)

Prominent stress response of Purkinje cells in Creutzfeldt-Jakob disease

Kovács, G. G., Kurucz, I., Budka, H., Ádori, C., Müller, F., Ács, P., Klöppel, S., Schätzl, H. M., Mayer, R. J. & László, L., jan. 1 2001, In : Neurobiology of Disease. 8, 5, p. 881-889 9 p.

Research output: Article

23 Citations (Scopus)

Protein processing in lysosomes: the new therapeutic target in neurodegenerative disease

Mayer, R. J., Landon, M., Laszlo, L., Lowe, J. & Lennox, G., júl. 18 1992, In : The Lancet. 340, 8812, p. 156-159 4 p.

Research output: Article

42 Citations (Scopus)

Rapidly progressive dementia with thalamic degeneration and peculiar cortical prion protein immunoreactivity, but absence of proteinase K resistant PrP: a new disease entity?

Kovacs, G. G., Peden, A., Weis, S., Höftberger, R., Berghoff, A. S., Yull, H., Ströbel, T., Koppi, S., Katzenschlager, R., Langenscheidt, D., Assar, H., Zaruba, E., Gröner, A., Voigtländer, T., Puska, G., Hametner, E., Grams, A., Muigg, A., Knoflach, M., László, L. & 3 others, Ironside, J. W., Head, M. W. & Budka, H., 2013, In : Acta neuropathologica communications. 1, 1, p. 72 1 p.

Research output: Article

10 Citations (Scopus)

Receptor-like properties of the 26 kDa transmembrane form of TNF

Domonkos, Á., Udvardy, A., László, L., Nagy, T. & Duda, E., 2001, In : European Cytokine Network. 12, 3, p. 411-419 9 p.

Research output: Article

41 Citations (Scopus)

Related organelles of the endosome-lysosome system contain a different repertoire of ubiquitinated proteins in Sf9 insect cells

Löw, P., Doherty, F. J., Fellinger, E., Sass, M., John Mayer, R. & László, L., júl. 10 1995, In : FEBS letters. 368, 1, p. 125-131 7 p.

Research output: Article

10 Citations (Scopus)

Serum amyloid P component induces neuronal apoptosis and β-amyloid immunoreactivity

Urbányi, Z., László, L., Tomasi, T. B., Tóth, E., Mekes, É., Sass, M. & Pázmány, T., okt. 24 2003, In : Brain research. 988, 1-2, p. 69-77 9 p.

Research output: Article

14 Citations (Scopus)
20 Citations (Scopus)

The abnormal isoform of the prion protein accumulates in late‐endosome‐like organelles in scrapie‐infected mouse brain

Arnold, J. E., Tipler, C., Laszlo, L., Hope, J., Landon, M. & Mayer, R. J., aug. 1995, In : The Journal of Pathology. 176, 4, p. 403-411 9 p.

Research output: Article

142 Citations (Scopus)