• 5324 Citations
  • 27 h-Index
1981 …2019

Research output per year

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Research Output

  • 5324 Citations
  • 27 h-Index
  • 67 Article
  • 8 Review article
  • 2 Comment/debate
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Article
1985
28 Citations (Scopus)
1986

The turnover of autophagic vacuoles: Evaluation by quantitative electron microscopy

Kovács, J., Fellinger, E., Kárpáti, P. A., Kovács, A. L. & László, L., dec. 1 1986, In : Biomedica Biochimica Acta. 45, 11-12, p. 1543-1547 5 p.

Research output: Article

10 Citations (Scopus)
1987
25 Citations (Scopus)

Immunochemical demonstration of ubiquitin conjugates in fibroblasts treated with cysteine proteinase inhibitors

Doherty, F. J., Osborn, N. U., Wassell, J. A., Laszlo, L. & Mayer, R. J., jan. 1 1989, In : Biochemical Society transactions. 17, 1, p. 171-172 2 p.

Research output: Article

4 Citations (Scopus)
8 Citations (Scopus)
8 Citations (Scopus)

Ubiquitin-protein conjugates accumulate in the lysosomal system of fibroblasts treated with cysteine proteinase inhibitors

Doherty, F. J., Osborn, N. U., Wassell, J. A., Heggie, P. E., Laszlo, L. & Mayer, R. J., jan. 1 1989, In : Biochemical Journal. 263, 1, p. 47-55 9 p.

Research output: Article

73 Citations (Scopus)
1990

Ubiquitinated protein conjugates are specifically enriched in the lysosomal system of fibroblasts

Laszlo, L., Doherty, F. J., Osborn, N. U. & John Mayer, R., febr. 26 1990, In : FEBS letters. 261, 2, p. 365-368 4 p.

Research output: Article

71 Citations (Scopus)
1991

Immunogold localisation of ubiquitin-protein conjugates in primary (azurophilic) granules of polymorphonuclear neutrophils

László, L., Doherty, F. J., Watson, A., Self, T., Landon, M., Lowe, J. & Mayer, R. J., febr. 25 1991, In : FEBS letters. 279, 2, p. 175-178 4 p.

Research output: Article

31 Citations (Scopus)

The degradative fate of ubiquitin-protein conjugates in nucleated and enucleated cells.

Watson, A. L., László, L. & Doherty, F. J., 1991, In : Acta biologica Hungarica. 42, 1-3, p. 49-56 8 p.

Research output: Article

3 Citations (Scopus)
38 Citations (Scopus)
7 Citations (Scopus)

Ubiquitin and the lysosome system: Molecular immunopathology reveals the connection

Mayer, R. J., Lowe, J., Landon, M., McDermott, H., Tuckwell, J., Doherty, F. & Laszlo, L., nov. 20 1991, In : Biomedica Biochimica Acta. 50, 4-6, p. 333-341 9 p.

Research output: Article

25 Citations (Scopus)
1992

A role for lysosomes in scrapie pathogenesis

Kenward, N., Laszlo, L., Landon, M., Fergusson, J., Lowe, J., McDermott, H., Hope, J., Brown, J. & Mayer, R. J., jan. 1 1992, In : Biochemical Society transactions. 20, 3, p. 265S

Research output: Article

4 Citations (Scopus)

Immunoreactivity to ubiquitin—protein conjugates is present early in the disease process in the brains of scrapie‐infected mice

Lowe, J., Fergusson, J., Kenward, N., Laszlo, L., Landon, M., Farquhar, C., Brown, J., Hope, J. & Mayer, R. J., okt. 1992, In : The Journal of Pathology. 168, 2, p. 169-177 9 p.

Research output: Article

35 Citations (Scopus)

Lysosomes as key organelles in the pathogenesis of prion encephalopathies

Laszlo, L., Lowe, J., Self, T., Kenward, N., Landon, M., McBride, T., Farquhar, C., McConnell, I., Brown, J., Hope, J. & Mayer, R. J., ápr. 1992, In : The Journal of Pathology. 166, 4, p. 333-341 9 p.

Research output: Article

144 Citations (Scopus)

Protein processing in lysosomes: the new therapeutic target in neurodegenerative disease

Mayer, R. J., Landon, M., Laszlo, L., Lowe, J. & Lennox, G., júl. 18 1992, In : The Lancet. 340, 8812, p. 156-159 4 p.

Research output: Article

42 Citations (Scopus)

Ubiquitin, Lysosomes, and Neurodegenerative Diseases

MAYER, R. JOHN., LASZLO, LAJOS., LANDON, MICHAEL., HOPE, JAMES. & LOWE, JAMES., dec. 1992, In : Annals of the New York Academy of Sciences. 674, 1, p. 149-160 12 p.

Research output: Article

10 Citations (Scopus)

Ubiquitin, lysosomes and neurodegenerative diseases

Mayer, R. J., Laszlo, L., Middleton, A., Landon, M., Hope, J. & Lowe, J., jan. 1 1992, In : Biochemical Society transactions. 20, 3, p. 645-648 4 p.

Research output: Article

6 Citations (Scopus)
1993
12 Citations (Scopus)
1994

Endosome-lysosomes and neurodegeneration

Mayer, R. J., Tipler, C., Laszlo, L., Arnold, J., Lowe, J. & Landon, M., 1994, In : Biomedicine and Pharmacotherapy. 48, 7, p. 282-286 5 p.

Research output: Article

9 Citations (Scopus)

Is there a common intracellular bioreactor in which amyloid formation is initiated in neurodegenerative diseases?

Mayer, R. J., Landon, M., Lowe, J., Tipler, C., Arnold, J. & Laszlo, L., jan. 1 1994, In : Biochemical Society transactions. 22, 1, p. 151-155 5 p.

Research output: Article

1995

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

Taraboulos, A., Scott, M., Semenov, A., Avraham, D., Laszlo, L. & Prusiner, S. B., ápr. 1995, In : Journal of Cell Biology. 129, 1, p. 121-132 12 p.

Research output: Article

489 Citations (Scopus)

Related organelles of the endosome-lysosome system contain a different repertoire of ubiquitinated proteins in Sf9 insect cells

Löw, P., Doherty, F. J., Fellinger, E., Sass, M., John Mayer, R. & László, L., júl. 10 1995, In : FEBS letters. 368, 1, p. 125-131 7 p.

Research output: Article

10 Citations (Scopus)

The abnormal isoform of the prion protein accumulates in late‐endosome‐like organelles in scrapie‐infected mouse brain

Arnold, J. E., Tipler, C., Laszlo, L., Hope, J., Landon, M. & Mayer, R. J., aug. 1995, In : The Journal of Pathology. 176, 4, p. 403-411 9 p.

Research output: Article

142 Citations (Scopus)
1996

Endosome-lysosomes, ubiquitin and neurodegeneration

Mayer, R. J., Tipler, C., Arnold, J., Laszlo, L., Al-Khedhairy, A., Lowe, J. & Landon, M., dec. 1 1996, In : Advances in experimental medicine and biology. 389, p. 261-269 9 p.

Research output: Article

35 Citations (Scopus)
25 Citations (Scopus)
1997

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis

Schätzl, H. M., Laszlo, L., Holtzman, D. M., Tatzelt, J., Dearmond, S. J., Weiner, R. I., Mobley, W. C. & Prusiner, S. B., nov. 1997, In : Journal of Virology. 71, 11, p. 8821-8831 11 p.

Research output: Article

Open Access
228 Citations (Scopus)

Ubiquitinated extracellular matrix proteins in insect cuticle

Löw, P., Borhegyi, N. H., Sass, M., László, L. & Reynolds, S. E., 1997, In : Biochemical Society transactions. 25, 3, p. 379S

Research output: Article

1999

Ultrastructural localization of Hsp-72 examined with a new polyclonal antibody raised against the truncated variable domain of the heat shock protein

Kurucz, I., Tombor, B., Prechl, J., Erdö, F., Hegedüs, E., Nagy, Z., Vitai, M., Korányi, L. & László, L., jún. 1999, In : Cell Stress and Chaperones. 4, 2, p. 139-152 14 p.

Research output: Article

41 Citations (Scopus)
2000

Clinicopathological phenotype of codon 129 valine homozygote sporadic Creutzfeldt-Jakob disease

Kovacs, G. G., Head, M. W., Bunn, T., Laszlo, L., Will, R. G. & Ironside, J. W., okt. 30 2000, In : Neuropathology and Applied Neurobiology. 26, 5, p. 463-472 10 p.

Research output: Article

35 Citations (Scopus)
2001

Cytotoxic effect of alcohol-withdrawal on primary cultures of cortical neurones

Nagy, J., Müller, F. & László, L., jan. 1 2001, In : Drug and Alcohol Dependence. 61, 2, p. 155-162 8 p.

Research output: Article

26 Citations (Scopus)

Inherited prion disease with A117V mutation of the prion protein gene: A novel Hungarian family

Kovács, G. G., Ertsey, C., Majtényi, C., Jelencsik, I., László, L., Flicker, H., Strain, L., Szirmai, I. & Budka, H., jún. 1 2001, In : Journal of Neurology Neurosurgery and Psychiatry. 70, 6, p. 802-805 4 p.

Research output: Article

16 Citations (Scopus)

Prominent stress response of Purkinje cells in Creutzfeldt-Jakob disease

Kovács, G. G., Kurucz, I., Budka, H., Ádori, C., Müller, F., Ács, P., Klöppel, S., Schätzl, H. M., Mayer, R. J. & László, L., jan. 1 2001, In : Neurobiology of Disease. 8, 5, p. 881-889 9 p.

Research output: Article

23 Citations (Scopus)

Receptor-like properties of the 26 kDa transmembrane form of TNF

Domonkos, Á., Udvardy, A., László, L., Nagy, T. & Duda, E., 2001, In : European Cytokine Network. 12, 3, p. 411-419 9 p.

Research output: Article

41 Citations (Scopus)
2002

Immunohistochemistry for the prion protein: Comparison of different monoclonal antibodies in human prion disease subtypes

Kovács, G. G., Head, M. W., Hegyi, I., Bunn, T. J., Flicker, H., Hainfellner, J. A., McCardle, L., László, L., Jarius, C., Ironside, J. W. & Budka, H., 2002, In : Brain Pathology. 12, 1, p. 1-11 11 p.

Research output: Article

91 Citations (Scopus)
30 Citations (Scopus)
2003

Serum amyloid P component induces neuronal apoptosis and β-amyloid immunoreactivity

Urbányi, Z., László, L., Tomasi, T. B., Tóth, E., Mekes, É., Sass, M. & Pázmány, T., okt. 24 2003, In : Brain research. 988, 1-2, p. 69-77 9 p.

Research output: Article

14 Citations (Scopus)
2004
25 Citations (Scopus)

Mouse in red: Red fluorescent protein expression in mouse ES cells, embryos, and adult animals

Vintersten, K., Monetti, C., Gertsenstein, M., Zhang, P., Laszlo, L., Biechele, S. & Nagy, A., dec. 1 2004, In : Genesis. 40, 4, p. 241-246 6 p.

Research output: Article

223 Citations (Scopus)

Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

Kovács, G. G., László, L., Kovács, J., Jensen, P. H., Lindersson, E., Botond, G., Molnár, T., Perczel, A., Hudecz, F., Mezo, G., Erdei, A., Tirián, L., Lehotzky, A., Gelpi, E., Budka, H. & Ovádi, J., nov. 1 2004, In : Neurobiology of Disease. 17, 2, p. 155-162 8 p.

Research output: Article

100 Citations (Scopus)

The prion protein in human neuromuscular diseases

Kovács, G. G., Kalev, O., Gelpi, E., Haberler, C., Wanschitz, J., Strohschneider, M., Molnár, M. J., László, L. & Budka, H., nov. 1 2004, In : Journal of Pathology. 204, 3, p. 241-247 7 p.

Research output: Article

12 Citations (Scopus)
2005

Increased incidence of genetic human prion disease in Hungary

Kovács, G. G., László, L., Bakos, A., Minárovits, J., Bishop, M. T., Ströbel, T., Vajna, B., Mitrova, E. & Majtényi, K., nov. 2005, In : Neurology. 65, 10, p. 1666-1669 4 p.

Research output: Article

15 Citations (Scopus)

The ubiquitin-proteasome system in Creutzfeldt-Jakob and Alzheimer disease: Intracellular redistribution of components correlates with neuronal vulnerability

Ádori, C., Kovács, G. G., Low, P., Molnár, K., Gorbea, C., Fellinger, E., Budka, H., Mayer, R. J. & László, L., aug. 1 2005, In : Neurobiology of Disease. 19, 3, p. 427-435 9 p.

Research output: Article

18 Citations (Scopus)
2006

Alterations of NADPH:protochlorophyllide oxidoreductase quantity and lipid composition in etiolated barley seedlings infected by Barley stripe mosaic virus (BSMV)

Harsányi, A., Ryberg, M., Andersson, M. X., Bóka, K., László, L., Botond, G., Böddi, B. & Gáborjányi, R., okt. 26 2006, In : Molecular Plant Pathology. 7, 6, p. 533-541 9 p.

Research output: Article

5 Citations (Scopus)
20 Citations (Scopus)
2007

Emberi prionbetegségek: magyarországi tapasztalatok.

Kovács, G. G., Bakos, A., Mitrova, E., Minárovits, J., László, L. & Majtényi, K., nov. 30 2007, In : Ideggyógyászati szemle. 60, 11-12, p. 447-452 6 p.

Research output: Article

8 Citations (Scopus)