• 3530 Citations
  • 28 h-Index
1970 …2018
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Research Output 1970 2018

  • 3530 Citations
  • 28 h-Index
  • 198 Article
  • 2 Chapter
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Article
2018
3 Citations (Scopus)

The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells

Sticz, T., Molnár, A., Dankó, T., Hujber, Z., Petővári, G., Nagy, N., Végső, G., Kópper, L. & Sebestyén, A., jún. 7 2018, (Accepted/In press) In : Pathology and Oncology Research. p. 1-8 8 p.

Research output: Article

Colon
Carcinoma
Raptors
Cell Line
Western Blotting
2017
10 Citations (Scopus)

Expression of mTORC1/2-related proteins in primary and brain metastatic lung adenocarcinoma

Krencz, I., Sebestyén, A., Fábián, K., Márk, Á., Moldvay, J., Khoor, A., Kópper, L. & Pápay, J., ápr. 1 2017, In : Human Pathology. 62, p. 66-73 8 p.

Research output: Article

Sirolimus
Neoplasm Metastasis
Brain
Proteins
S 6
2015
9 Citations (Scopus)

Rapamycin can restore the negative regulatory function of transforming growth factor beta 1 in high grade lymphomas

Sebestyén, A., Márk, Á., Hajdu, M., Nagy, N., Molnár, A., Végso, G., Barna, G. & Kópper, L., jún. 1 2015, In : Cytokine. 73, 2, p. 219-224 6 p.

Research output: Article

Sirolimus
Transforming Growth Factor beta
Non-Hodgkin's Lymphoma
Apoptosis
Lymphoma
2014
19 Citations (Scopus)

Expression of Certain Leukemia/Lymphoma Related microRNAs and its Correlation with Prognosis in Childhood Acute Lymphoblastic Leukemia

Nemes, K., Csóka, M., Nagy, N., Márk, Á., Váradi, Z., Dankó, T., Kovács, G., Kópper, L. & Sebestyén, A., nov. 12 2014, In : Pathology and Oncology Research. 21, 3, p. 597-604 8 p.

Research output: Article

MicroRNAs
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lymphoma
Leukemia
Prednisolone
41 Citations (Scopus)

Major partial response to crizotinib, a dual MET/ALK inhibitor, in a squamous cell lung (SCC) carcinoma patient with de novo c-MET amplification in the absence of ALK rearrangement

Schwab, R., Peták, I., Kollar, M., Pinter, F., Varkondi, E., Kohanka, A., Barti-Juhasz, H., Schönleber, J., Brauswetter, D., Kópper, L. & Urban, L., jan. 2014, In : Lung Cancer. 83, 1, p. 109-111 3 p.

Research output: Article

Epithelial Cells
Carcinoma
Lung
Squamous Cell Carcinoma
Pericarditis
2013
19 Citations (Scopus)
Hodgkin Disease
Mantle-Cell Lymphoma
NF-kappa B
Sirolimus
Therapeutics
14 Citations (Scopus)

Mammalian Target of Rapamycin (mTOR) Activity Dependent Phospho-Protein Expression in Childhood Acute Lymphoblastic Leukemia (ALL)

Nemes, K., Sebestyén, A., Márk, Á., Hajdu, M., Kenessey, I., Sticz, T., Nagy, E., Barna, G., Váradi, Z., Kovács, G., Kópper, L. & Csóka, M., ápr. 3 2013, In : PLoS One. 8, 4, e59335.

Research output: Article

lymphocytic leukemia
Sirolimus
Precursor Cell Lymphoblastic Leukemia-Lymphoma
childhood
protein synthesis
2012
12 Citations (Scopus)

Activity and complexes of mTOR in diffuse large B-cell lymphomas - A tissue microarray study

Sebestyén, A., Sticz, T. B., Márk, Á., Hajdu, M., Timár, B., Nemes, K., Nagy, N., Váradi, Z. & Kópper, L., dec. 2012, In : Modern Pathology. 25, 12, p. 1623-1628 6 p.

Research output: Article

Lymphoma, Large B-Cell, Diffuse
Sirolimus
Phosphoproteins
Patient Selection
TOR Serine-Threonine Kinases
4 Citations (Scopus)

A tudorák megelozésének, diagnosztikájának és kezelésének alapelvei.

Ostoros, G., András, B., Zoltán, B., Katalin, B., Attila, C., Janos, F., Maria, G., Akos, H., Lászlo, K., Kópper, L., Gabor, K., Losonczy, G., Judit, M., Tamas, M. F., Zsuzsa, M., Pál, R., Zsolt, O., Strausz, J., Szentirmay, Z., István, S. & 4 others, Klára, S., Tímár, J., Tolnay, E. & NEFMI - Nemzeti Eroforras Miniszterium (Department of Human Resources), . N. E. M. D. O. H. R., máj. 2012, In : Magyar Onkologia. 56, 2, p. 114-132 19 p.

Research output: Article

Proto-Oncogene Proteins
Adjuvant Chemoradiotherapy
Molecular Targeted Therapy
ras Proteins
Neoadjuvant Therapy
6 Citations (Scopus)

A tüdo{double acute}rák megelo{double acute} zésének, diagnosztikájának és kezelésének alapelvei

Ostoros, G., Bajcsay, A., Balikó, Z., Borbély, K., Csekeo, A., Fillinger, J., Godény, M., Horváth, Á., Kecskés, L., Kópper, L., Kovács, G., Losonczy, G., Moldvay, J., Molnár, F. T., Monostori, Z., Rahóty, P., Orosz, Z., Strausz, J., Szentirmay, Z., Szilágyi, I. & 3 others, Szondy, K., Tímár, J. & Tolnay, E., 2012, In : Magyar Onkologia. 56, 2, p. 114-132 19 p.

Research output: Article

4 Citations (Scopus)
Osteoclasts
Neoplasm Metastasis
Bone and Bones
Cathepsin K
Selective Estrogen Receptor Modulators
2011
15 Citations (Scopus)

Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone

Balla, P., Moskovszky, L., Sápi, Z., Forsyth, R., Knowles, H., Athanasou, N. A., Szendrői, M., Kópper, L., Rajnai, H., Pinter, F., Peták, I., Benassi, M. S., Picci, P., Conti, A. & Krenács, T., szept. 2011, In : Histopathology. 59, 3, p. 376-389 14 p.

Research output: Article

Giant Cell Tumor of Bone
Stromal Cells
Epidermal Growth Factor Receptor
Osteogenesis
Disease Progression
5 Citations (Scopus)
Ribosomal Protein S6
S 6
Lymphoma
Cell Cycle
Phosphotransferases
Spiders
Sirolimus
Neoplasms
Kidney Neoplasms
Astrocytoma
2010
15 Citations (Scopus)

Centrosome abnormalities in giant cell tumour of bone: Possible association with chromosomal instability

Moskovszky, L., Dezsö, K., Athanasou, N., Szendrői, M., Kópper, L., Kliskey, K., Picci, P. & Sápi, Z., márc. 2010, In : Modern Pathology. 23, 3, p. 359-366 8 p.

Research output: Article

Giant Cell Tumor of Bone
Centrosome
Chromosomal Instability
Tubulin
Neoplasms
2 Citations (Scopus)

High resolution melting curve analysis of DNA sequence alterations of various sizes

Becságh, P., Varga, K., Szakács, O., Kópper, L. & Orosz, Z., szept. 2010, In : Pathology and Oncology Research. 16, 3, p. 421-426 6 p.

Research output: Article

DNA Sequence Analysis
Freezing
Single-Stranded Conformational Polymorphism
Workflow
Nucleic Acids
45 Citations (Scopus)
Molecular Pathology
Drug Discovery
Epidermal Growth Factor Receptor
Pharmaceutical Preparations
Drug Delivery Systems
2 Citations (Scopus)

Panitumumab: An arrow on target

Kópper, L., jún. 2010, In : Pathology and Oncology Research. 16, 2, p. 143-148 6 p.

Research output: Article

Colorectal Neoplasms
Therapeutics
Monoclonal Antibodies
Drug Therapy
panitumumab
Precision Medicine
Hungary
Pharmacogenetics
Research
Population
2009

A célzott terápia - Paradigmaváltás az onkológiában

Kópper, L., 2009, In : Orvoskepzes. 84, 3, p. 157-161 5 p.

Research output: Article

Therapeutics
Growth and Development
Blood Vessels
Neoplasms
3-chloro-4,4-dimethyl-2-oxazolidinone

A központi idegrendszeri daganatok célzott terá piája

Kópper, L., 2009, In : Orvoskepzes. 84, 3, p. 247-252 6 p.

Research output: Article

Angiogenesis Inhibitors
Glioblastoma
MicroRNAs
Radio
Brain Neoplasms
2 Citations (Scopus)
Validation Studies
Colorectal Neoplasms
Mutation
Molecular Targeted Therapy
Medical Oncology
10 Citations (Scopus)

Expression of TGFβ1 and its signaling components by peripheral lymphocytes in systemic lupus erythematosus

Kohut, E., Hajdu, M., Gergely, P., Gopcsa, L., Kilián, K., Pálóczi, K., Kópper, L. & Sebestyén, A., jún. 2009, In : Pathology and Oncology Research. 15, 2, p. 251-256 6 p.

Research output: Article

Transforming Growth Factors
Systemic Lupus Erythematosus
Lymphocytes
Cytokines
Immunosuppressive Agents
31 Citations (Scopus)

Genomic instability in giant cell tumor of bone. A study of 52 cases using DNA ploidy, relocalization FISH, and array-CGH analysis

Moskovszky, L., Szuhai, K., Krenács, T., Hogendoorn, P. C. W., Szendrői, M., Benassi, M. S., Kópper, L., Füle, T. & Sápi, Z., jún. 2009, In : Genes Chromosomes and Cancer. 48, 6, p. 468-479 12 p.

Research output: Article

Giant Cell Tumor of Bone
Comparative Genomic Hybridization
Ploidies
Genomic Instability
Fluorescence In Situ Hybridization
6 Citations (Scopus)
B-Cell Lymphoma
Amyloid Precursor Protein Secretases
Transforming Growth Factor beta
Non-Hodgkin's Lymphoma
Apoptosis
2008
16 Citations (Scopus)
Microscopy
Squamous Cell Carcinoma
Keratinocytes
Monoclonal Antibodies
Basosquamous Carcinoma
62 Citations (Scopus)

Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry

Pinter, F., Papay, J., Almasi, A., Sápi, Z., Szabo, E., Kanya, M., Tamasi, A., Jori, B., Varkondi, E., Moldvay, J., Szondy, K., Kéri, G., Dominici, M., Conte, P., Eckhardt, S., Kópper, L., Schwab, R. & Peták, I., márc. 2008, In : Journal of Molecular Diagnostics. 10, 2, p. 160-168 9 p.

Research output: Article

erbB-1 Genes
Gene Dosage
Epidermal Growth Factor Receptor
Fluorescence In Situ Hybridization
Immunohistochemistry
44 Citations (Scopus)

Lapatinib: A sword with two edges

Kópper, L., márc. 2008, In : Pathology and Oncology Research. 14, 1, p. 1-8 8 p.

Research output: Article

Protein-Tyrosine Kinases
Diarrhea
Clinical Trials
Breast Neoplasms
Neoplasm Metastasis
17 Citations (Scopus)
Mantle-Cell Lymphoma
B-Cell Chronic Lymphocytic Leukemia
Differential Diagnosis
Fluorescence
B-Lymphocytes
2007
13 Citations (Scopus)

Activity of the notch-signalling pathway in circulating human chronic lymphocytic leukaemia cells

Hajdu, M., Sebestyén, A., Barna, G., Reiniger, L., Jánosi, J., Sréter, L., Várkonyi, J., Demeter, J. & Kópper, L., márc. 2007, In : Scandinavian Journal of Immunology. 65, 3, p. 271-275 5 p.

Research output: Article

B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
Lymphoid Tissue
Messenger RNA
Genes
34 Citations (Scopus)
Mycophenolic Acid
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Lymphoma
SCID Mice
5 Citations (Scopus)

Functional evaluation of multidrug resistance transporter activity in surgical samples of solid tumors

Schwab, R., Micsik, T., Szokolóczi, O., Schafer, E., Tihanyi, B., Tihanyi, T., Kupcsulik, P., Diófalvi, K., Mersich, T., Besznyak, I., Zarand, A., Mihalik, R., Sarkadi, B., Kéri, G., Pap, A., Jakab, F., Kópper, L. & Peták, I., aug. 2007, In : Assay and Drug Development Technologies. 5, 4, p. 541-550 10 p.

Research output: Article

Multiple Drug Resistance
P-Glycoprotein
Neoplasms
Collagenases
Epithelial Cells
2 Citations (Scopus)

IgVH gene mutation status and genomic imbalances in chronic lymphocytic leukaemia with increased prolymphocytes (CLL/PL)

Balogh, Z., Reiniger, L., Deák, L., Bödör, C., Csomor, J., Szepesi, Á., Gagyi, É., Kópper, L. & Matolcsy, A., jún. 2007, In : Hematological Oncology. 25, 2, p. 90-95 6 p.

Research output: Article

B-Cell Chronic Lymphocytic Leukemia
Mutation
Genes
Comparative Genomic Hybridization
Clonal Evolution
30 Citations (Scopus)
Non-Small Cell Lung Carcinoma
Cellular Apoptosis Susceptibility Protein
Catenins
Brain
Caspase 9

In this issue

Kopper, L., 2007, In : Pathology and Oncology Research. 13, 4, p. 267 1 p.

Research output: Article

In this issue

Kópper, L. & Tímár, J., 2007, In : Pathology and Oncology Research. 13, 3, p. 179 1 p.

Research output: Article

9 Citations (Scopus)
Transforming Growth Factor beta1
Transforming Growth Factor beta
Lymphoma
B-Cell Lymphoma
Apoptosis
2006
5 Citations (Scopus)
Molecular Targeted Therapy
Molecular Pathology
Renal Cell Carcinoma
Standard of Care
Protein-Tyrosine Kinases

Célzott gyógyszeres kezelés az onkológiá ban

Kópper, L., 2006, In : Orvoskepzes. 81, 3, p. 141-144 4 p.

Research output: Article

Drug Therapy
Neoplasms
Hand
Growth
Pharmaceutical Preparations
29 Citations (Scopus)
Genomics
Renal Cell Carcinoma
Galectin 3
Parvalbumins
Vimentin

In this issue

Kópper, L., dec. 31 2006, In : Pathology and Oncology Research. 12, 4, p. 195 1 p.

Research output: Article

31 Citations (Scopus)

Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria

Nagy, K., Székely-Szüts, K., Izeradjene, K., Douglas, L., Tillman, M., Barti-Juhász, H., Dominici, M., Spano, C., Cervo, G. L., Conte, P., Houghton, J. A., Mihalik, R., Kópper, L. & Peták, I., 2006, In : Pathology and Oncology Research. 12, 3, p. 133-142 10 p.

Research output: Article

TNF-Related Apoptosis-Inducing Ligand
Proteasome Inhibitors
Mitochondria
Colon
Caspase 3
Medical Oncology
Proteomics
Biomarkers
Neoplasms
Protein Array Analysis
38 Citations (Scopus)

Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation

Reiniger, L., Bödör, C., Bognár, Á., Balogh, Z., Csomor, J., Szepesi, Á., Kópper, L. & Matolcsy, A., jún. 2006, In : Leukemia. 20, 6, p. 1089-1095 7 p.

Research output: Article

B-Cell Chronic Lymphocytic Leukemia
Messenger RNA
Non-Hodgkin's Lymphoma
B-Cell Lymphoma
Mutation Rate
1 Citation (Scopus)
Organ Transplantation
Neoplasms
Immunosuppressive Agents
Immunosuppression
Lip Neoplasms
Transforming Growth Factor beta
Carcinogens
Cytokines
Neoplasms
Transforming Growth Factor beta Receptors
2 Citations (Scopus)

Tumor-ossejtek - egy lehetséges forgatókönyv

Kópper, L. & Hajdú, M., 2006, In : Magyar Onkologia. 50, 2, p. 101-106 6 p.

Research output: Article

Neoplastic Stem Cells
Stem Cells
Neoplasms
Adult Stem Cells
Growth
2005
22 Citations (Scopus)

Aberrant somatic hypermutation and expression of activation-induced cytidine deaminase mRNA in mediastinal large B-cell lymphoma

Bödör, C., Bognár, Á., Reiniger, L., Szepesi, Á., Tóth, E., Kópper, L. & Matolcsy, A., máj. 2005, In : British Journal of Haematology. 129, 3, p. 373-376 4 p.

Research output: Article

B-Cell Lymphoma
Messenger RNA
Gene Expression
Mutation
AICDA (activation-induced cytidine deaminase)
23 Citations (Scopus)

Alpha-fetoprotein expression is a potential prognostic marker in hepatocellular carcinoma

Görög, D., Regöly-Mérei, J., Paku, S., Kópper, L. & Nagy, P., aug. 28 2005, In : World Journal of Gastroenterology. 11, 32, p. 5015-5018 4 p.

Research output: Article

alpha-Fetoproteins
Hepatocellular Carcinoma
Catenins
Neoplasms
Staining and Labeling
23 Citations (Scopus)

Clonal selection in the bone marrow involvement of follicular lymphoma

Bognár, Á., Csernus, B., Bödör, C., Reiniger, L., Szepesi, Á., Tóth, E., Kópper, L. & Matolcsy, A., szept. 2005, In : Leukemia. 19, 9, p. 1656-1662 7 p.

Research output: Article

Follicular Lymphoma
Bone Marrow
Lymph Nodes
Neoplasms
Immunoglobulin Variable Region