• 1585 Citations
  • 22 h-Index
19982019

Research output per year

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Research Output

  • 1585 Citations
  • 22 h-Index
  • 55 Article
  • 2 Review article
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Article
2019
Open Access
4 Citations (Scopus)
Open Access

Mechanisms Associated with Type 2 Diabetes as a Risk Factor for Alzheimer-Related Pathology

Su, M., Naderi, K., Samson, N., Youssef, I., Fülöp, L., Bozso, Z., Laroche, S., Delatour, B. & Davis, S., aug. 15 2019, In : Molecular Neurobiology. 56, 8, p. 5815-5834 20 p.

Research output: Article

4 Citations (Scopus)
2018

Exceptional in vivo catabolism of neurodegeneration-related aggregates

Datki, Z., Olah, Z., Hortobagyi, T., Macsai, L., Zsuga, K., Fulop, L., Bozso, Z., Galik, B., Acs, E., Foldi, A., Szarvas, A. & Kalman, J., jan. 1 2018, In : Zoological Letters. 4, 1, 6.

Research output: Article

3 Citations (Scopus)

GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome

Milenkovic, I., Stojanovic, T., Aronica, E., Fülöp, L., Bozsó, Z., Máté, Z., Yanagawa, Y., Adle-Biassette, H., Lubec, G., Szabó, G., Harkany, T., Kovács, G. G. & Keimpema, E., ápr. 1 2018, In : Brain Structure and Function. 223, 3, p. 1501-1518 18 p.

Research output: Article

2 Citations (Scopus)

Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier

Mészáros, M., Porkoláb, G., Kiss, L., Pilbat, A. M., Kóta, Z., Kupihár, Z., Kéri, A., Galbács, G., Siklós, L., Tóth, A., Fülöp, L., Csete, M., Sipos, Á., Hülper, P., Sipos, P., Páli, T., Rákhely, G., Szabó-Révész, P., Deli, M. A. & Veszelka, S., okt. 15 2018, In : European Journal of Pharmaceutical Sciences. 123, p. 228-240 13 p.

Research output: Article

8 Citations (Scopus)

Peripheral cyclic β-amino acids balance the stability and edge-protection of β-sandwiches

Olajos, G., Hetényi, A., Wéber, E., Szögi, T., Fülöp, L. & Martinek, T. A., jan. 1 2018, In : Organic and Biomolecular Chemistry. 16, 30, p. 5492-5499 8 p.

Research output: Article

Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer

Gera, J., Szögi, T., Bozsó, Z., Fülöp, L., Barrera, E. E., Rodriguez, A. M., Méndez, L., Delpiccolo, C. M. L., Mata, E. G., Cioffi, F., Broersen, K., Paragi, G. & Enriz, R. D., dec. 1 2018, In : Bioorganic Chemistry. 81, p. 211-221 11 p.

Research output: Article

2 Citations (Scopus)

Structural optimization of foldamer-dendrimer conjugates as multivalent agents against the toxic effects of amyloid beta oligomers

Bartus, É., Olajos, G., Schuster, I., Bozsó, Z., Deli, M. A., Veszelka, S., Walter, F. R., Datki, Z., Szakonyi, Z., Martinek, T. A. & Fülöp, L., okt. 2 2018, In : Molecules. 23, 10, 2523.

Research output: Article

2 Citations (Scopus)
2017

Biotin and glutathione targeting of solid nanoparticles to cross human brain endothelial cells

Veszelka, S., Mészáros, M., Kiss, L., Kóta, Z., Páli, T., Hoyk, Z., Bozsó, Z., Fülöp, L., Tóth, A., Rákhely, G. & Deli, M. A., aug. 1 2017, In : Current pharmaceutical design. 23, 28, p. 4198-4205 8 p.

Research output: Article

5 Citations (Scopus)

New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design

Gutierrez, L. J., Angelina, E., Gyebrovszki, A., Fülöp, L., Peruchena, N., Baldoni, H. A., Penke, B. & Enriz, R. D., jan. 25 2017, In : Journal of Biomolecular Structure and Dynamics. 35, 2, p. 413-426 14 p.

Research output: Article

9 Citations (Scopus)
16 Citations (Scopus)
2016
21 Citations (Scopus)

Reversible Opening of Intercellular Junctions of Intestinal Epithelial and Brain Endothelial Cells with Tight Junction Modulator Peptides

Bocsik, A., Walter, F. R., Gyebrovszki, A., Fülöp, L., Blasig, I., Dabrowski, S., Ötvös, F., Tóth, A., Rákhely, G., Veszelka, S., Vastag, M., Szabó-Révész, P. & Deli, M., febr. 1 2016, In : Journal of Pharmaceutical Sciences. 105, 2, p. 754-765 12 p.

Research output: Article

32 Citations (Scopus)
2015
12 Citations (Scopus)

Amyloid-like fibril formation by trypsin in aqueous ethanol. inhibition of fibrillation by PEG

Kotormán, M., Simon, L. M., Borics, A., Szabó, M. R., Szabó, K., Szögi, T. & Fülöp, L., dec. 1 2015, In : Protein and Peptide Letters. 22, 12, p. 1104-1110 7 p.

Research output: Article

5 Citations (Scopus)
25 Citations (Scopus)

Opposite effect of Ca2+/Mg2+ ions on the aggregation of native and precursor-derived Aβ42

Bogár, F., Simon, D., Bozsó, Z., Janáky, T., Veszelka, S., Tóth, A. E., Deli, M. A., Borics, A., Násztor, Z., Gyebrovszki, A., Penke, B. & Fülöp, L., dec. 1 2015, In : Structural Chemistry. 26, 5-6, p. 1389-1403 15 p.

Research output: Article

2 Citations (Scopus)
2014
13 Citations (Scopus)
23 Citations (Scopus)

IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology

Liu, Y., Liu, X., Hao, W., Decker, Y., Schomburg, R., Fülöp, L., Pasparakis, M., Menger, M. D. & Fassbender, K., szept. 24 2014, In : Journal of Neuroscience. 34, 39, p. 12982-12999 18 p.

Research output: Article

18 Citations (Scopus)
13 Citations (Scopus)
2013
22 Citations (Scopus)

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease

Zilberter, M., Ivanov, A., Ziyatdinova, S., Mukhtarov, M., Malkov, A., Alpár, A., Tortoriello, G., Botting, C. H., Fülöp, L., Osypov, A. A., Pitkänen, A., Tanila, H., Harkany, T. & Zilberter, Y., ápr. 1 2013, In : Journal of neurochemistry. 125, 1, p. 157-171 15 p.

Research output: Article

38 Citations (Scopus)

Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit

Veszelka, S., Tóth, A. E., Walter, F. R., Datki, Z., Mózes, E., Fülöp, L., Bozsó, Z., Hellinger, É., Vastag, M., Orsolits, B., Környei, Z., Penke, B. & Deli, M. A., 2013, In : Journal of Alzheimer's Disease. 36, 3, p. 487-501 15 p.

Research output: Article

35 Citations (Scopus)
2012

A foldamer-dendrimer conjugate neutralizes synaptotoxic β-amyloid oligomers

Fülöp, L., Mándity, I. M., Juhász, G., Szegedi, V., Hetényi, A., Wéber, E., Bozsó, Z., Simon, D., Benko, M., Király, Z. & Martinek, T. A., júl. 30 2012, In : PloS one. 7, 7, e39485.

Research output: Article

31 Citations (Scopus)

Conformational dynamics of titin PEVK explored with FRET spectroscopy

Huber, T., Grama, L., Hetényi, C., Schay, G., Fülöp, L., Penke, B. & Kellermayer, M. S. Z., okt. 3 2012, In : Biophysical journal. 103, 7, p. 1480-1489 10 p.

Research output: Article

7 Citations (Scopus)
30 Citations (Scopus)

The formation of amyloid-like fibrils of αchymotrypsin in different aqueous organic solvents

Simon, L. M., Laczkó, I., Demcsák, A., Tóth, D., Kotormán, M. & Fülöp, L., máj. 1 2012, In : Protein and Peptide Letters. 19, 5, p. 544-550 7 p.

Research output: Article

9 Citations (Scopus)
2011

Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation

Virok, D. P., Simon, D., Bozsó, Z., Rajkó, R., Datki, Z., Bálint, É., Szegedi, V., Janáky, T., Penke, B. & Fülöp, L., ápr. 1 2011, In : Journal of Proteome Research. 10, 4, p. 1538-1547 10 p.

Research output: Article

19 Citations (Scopus)
2010
52 Citations (Scopus)

Controlled in situ preparation of Aβ(1-42) oligomers from the isopeptide "iso-Aβ(1-42)", physicochemical and biological characterization

Bozso, Z., Penke, B., Simon, D., Laczkó, I., Juhász, G., Szegedi, V., Kasza, Á., Soós, K., Hetényi, A., Wéber, E., Tóháti, H., Csete, M., Zarándi, M. & Fülöp, L., febr. 1 2010, In : Peptides. 31, 2, p. 248-256 9 p.

Research output: Article

35 Citations (Scopus)

Effect of nanogold particles on coupled plasmon resonance on biomolecule covered prepatterned multilayers

Sipos, Á., Tóháti, H., Mathesz, A., Szalai, A., Budai, J., Deli, M. A., Fülöp, L., Köházi-Kis, A., Csete, M. & Bor, Z., jún. 1 2010, In : Sensor Letters. 8, 3, p. 512-520 9 p.

Research output: Article

2 Citations (Scopus)

Fibrillar Aβ1-42enhances NMDA receptor sensitivity via the integrin signaling pathway

Juhász, G., Barkóczi, B., Vass, G., Datki, Z., Hunya, Á., Fülöp, L., Budai, D., Penke, B. & Szegedi, V., jan. 1 2010, In : Journal of Alzheimer's Disease. 19, 3, p. 1055-1067 13 p.

Research output: Article

13 Citations (Scopus)
99 Citations (Scopus)

Intranasal delivery of human β-amyloid peptide in rats: Effective brain targeting

Sipos, E., Kurunczi, A., Fehér, A., Penke, Z., Fülöp, L., Kasza, Á., Horváth, J., Horvát, S., Veszelka, S., Balogh, G., Kürti, L., Eros, I., Szabó-Révész, P., Párducz, Á., Penke, B. & Deli, M. A., ápr. 1 2010, In : Cellular and Molecular Neurobiology. 30, 3, p. 405-413 9 p.

Research output: Article

23 Citations (Scopus)

Protection of the blood-brain barrier by pentosan against amyloid-β-induced toxicity

Deli, M. A., Veszelka, S., Csiszár, B., Tóth, A., Kittel, Á., Csete, M., Sipos, Á., Szalai, A., Fülöp, L., Penke, B., Ábrahám, C. S. & Niwa, M., 2010, In : Journal of Alzheimer's Disease. 22, 3, p. 777-794 18 p.

Research output: Article

16 Citations (Scopus)

Two pyridine derivatives as potential Cu(ii) and Zn(ii) chelators in therapy for Alzheimer's disease

Lakatos, A., Zsigó, É., Hollender, D., Nagy, N. V., Fülöp, L., Simon, D., Bozsó, Z. & Kiss, T., febr. 22 2010, In : Dalton Transactions. 39, 5, p. 1302-1315 14 p.

Research output: Article

32 Citations (Scopus)
2009

Amyloid β-induced neuronal hyperexcitability triggers progressive epilepsy

Minkeviciene, R., Rheims, S., Dobszay, M. B., Zilberter, M., Hartikainen, J., Fülöp, L., Penke, B., Zilberter, Y., Harkany, T., Pitkänen, A. & Tanila, H., márc. 18 2009, In : Journal of Neuroscience. 29, 11, p. 3453-3462 10 p.

Research output: Article

321 Citations (Scopus)
16 Citations (Scopus)
2008
15 Citations (Scopus)

Characterization of the interaction between Aβ 1-42 and glyceraldehyde phosphodehydrogenase

Verdier, Y., Földi, I., Sergeant, N., Fülöp, L., Penke, Z., Janáky, T., Szücs, M. & Penke, B., jún. 1 2008, In : Journal of Peptide Science. 14, 6, p. 755-762 8 p.

Research output: Article

22 Citations (Scopus)
5 Citations (Scopus)
2007

Synthesis of Aβ(1-42) and its derivatives with improved efficiency

Zarándi, M., Soós, K., Fülöp, L., Bozsó, Z., Datki, Z., Tóth, G. K. & Penke, B., febr. 1 2007, In : Journal of Peptide Science. 13, 2, p. 94-99 6 p.

Research output: Article

40 Citations (Scopus)
2006
100 Citations (Scopus)

Endomorphin-2, an endogenous tetrapeptide, protects against Aβ1-42 in vitro and in vivo

Szegedi, V., Juhá, G., Rózsa, É., Juhász-Vedres, G., Datki, Z., Fülöp, L., Bozsó, Z., Lakatos, A., Laczkó, I., Farkas, T., Kis, Z., Tóth, G., Soós, K., Zarándi, M., Budai, D., Toldi, J. & Penke, B., jún. 1 2006, In : FASEB Journal. 20, 8, p. E324-E333

Research output: Article

21 Citations (Scopus)

Non-fibrillar β-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors

Shemer, I., Holmgren, C., Min, R., Fülöp, L., Zilberter, M., Sousa, K. M., Farkas, T., Härtig, W., Penke, B., Burnashev, N., Tanila, H., Zilberter, Y. & Harkany, T., ápr. 1 2006, In : European Journal of Neuroscience. 23, 8, p. 2035-2047 13 p.

Research output: Article

62 Citations (Scopus)
2005

Identification of synaptic plasma membrane proteins co-precipitated with fibrillar β-amyloid peptide

Verdier, Y., Huszár, E., Penke, B., Penke, Z., Woffendin, G., Scigelova, M., Fülöp, L., Szucs, M., Medzihradszky, K. & Janaky, T., aug. 1 2005, In : Journal of neurochemistry. 94, 3, p. 617-628 12 p.

Research output: Article

22 Citations (Scopus)

Pentapeptides derived from Aβ1-42 protect neurons from the modulatory effect of Aβ fibrils-an in vitro and in vivo electrophysiological study

Szegedi, V., Fülöp, L., Farkas, T., Rózsa, E., Robotka, H., Kis, Z., Penke, Z., Horváth, S., Molnár, Z., Datki, Z., Soós, K., Toldi, J., Budai, D., Zarándi, M. & Penke, B., ápr. 2005, In : Neurobiology of Disease. 18, 3, p. 499-508 10 p.

Research output: Article

21 Citations (Scopus)