• 1602 Citations
  • 22 h-Index
19982019

Research output per year

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Research Output

  • 1602 Citations
  • 22 h-Index
  • 55 Article
  • 2 Review article
34 Citations (Scopus)

Two pyridine derivatives as potential Cu(ii) and Zn(ii) chelators in therapy for Alzheimer's disease

Lakatos, A., Zsigó, É., Hollender, D., Nagy, N. V., Fülöp, L., Simon, D., Bozsó, Z. & Kiss, T., febr. 22 2010, In : Dalton Transactions. 39, 5, p. 1302-1315 14 p.

Research output: Article

32 Citations (Scopus)
21 Citations (Scopus)

The formation of amyloid-like fibrils of αchymotrypsin in different aqueous organic solvents

Simon, L. M., Laczkó, I., Demcsák, A., Tóth, D., Kotormán, M. & Fülöp, L., máj. 1 2012, In : Protein and Peptide Letters. 19, 5, p. 544-550 7 p.

Research output: Article

10 Citations (Scopus)

Synthesis of Aβ(1-42) and its derivatives with improved efficiency

Zarándi, M., Soós, K., Fülöp, L., Bozsó, Z., Datki, Z., Tóth, G. K. & Penke, B., febr. 1 2007, In : Journal of Peptide Science. 13, 2, p. 94-99 6 p.

Research output: Article

40 Citations (Scopus)

Synthesis and fluorescent labeling of beta-amyloid peptides

Fülöp, L., Penke, B. & Zarándi, M., szept. 5 2001, In : Journal of Peptide Science. 7, 8, p. 397-401 5 p.

Research output: Article

23 Citations (Scopus)
16 Citations (Scopus)

Structural optimization of foldamer-dendrimer conjugates as multivalent agents against the toxic effects of amyloid beta oligomers

Bartus, É., Olajos, G., Schuster, I., Bozsó, Z., Deli, M. A., Veszelka, S., Walter, F. R., Datki, Z., Szakonyi, Z., Martinek, T. A. & Fülöp, L., okt. 2 2018, In : Molecules. 23, 10, 2523.

Research output: Article

2 Citations (Scopus)
13 Citations (Scopus)

Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer

Gera, J., Szögi, T., Bozsó, Z., Fülöp, L., Barrera, E. E., Rodriguez, A. M., Méndez, L., Delpiccolo, C. M. L., Mata, E. G., Cioffi, F., Broersen, K., Paragi, G. & Enriz, R. D., dec. 1 2018, In : Bioorganic Chemistry. 81, p. 211-221 11 p.

Research output: Article

2 Citations (Scopus)

Reversible Opening of Intercellular Junctions of Intestinal Epithelial and Brain Endothelial Cells with Tight Junction Modulator Peptides

Bocsik, A., Walter, F. R., Gyebrovszki, A., Fülöp, L., Blasig, I., Dabrowski, S., Ötvös, F., Tóth, A., Rákhely, G., Veszelka, S., Vastag, M., Szabó-Révész, P. & Deli, M., febr. 1 2016, In : Journal of Pharmaceutical Sciences. 105, 2, p. 754-765 12 p.

Research output: Article

33 Citations (Scopus)
21 Citations (Scopus)

Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation

Virok, D. P., Simon, D., Bozsó, Z., Rajkó, R., Datki, Z., Bálint, É., Szegedi, V., Janáky, T., Penke, B. & Fülöp, L., ápr. 1 2011, In : Journal of Proteome Research. 10, 4, p. 1538-1547 10 p.

Research output: Article

19 Citations (Scopus)

Protection of the blood-brain barrier by pentosan against amyloid-β-induced toxicity

Deli, M. A., Veszelka, S., Csiszár, B., Tóth, A., Kittel, Á., Csete, M., Sipos, Á., Szalai, A., Fülöp, L., Penke, B., Ábrahám, C. S. & Niwa, M., 2010, In : Journal of Alzheimer's Disease. 22, 3, p. 777-794 18 p.

Research output: Article

17 Citations (Scopus)

Peripheral cyclic β-amino acids balance the stability and edge-protection of β-sandwiches

Olajos, G., Hetényi, A., Wéber, E., Szögi, T., Fülöp, L. & Martinek, T. A., jan. 1 2018, In : Organic and Biomolecular Chemistry. 16, 30, p. 5492-5499 8 p.

Research output: Article

Pentapeptides derived from Aβ1-42 protect neurons from the modulatory effect of Aβ fibrils-an in vitro and in vivo electrophysiological study

Szegedi, V., Fülöp, L., Farkas, T., Rózsa, E., Robotka, H., Kis, Z., Penke, Z., Horváth, S., Molnár, Z., Datki, Z., Soós, K., Toldi, J., Budai, D., Zarándi, M. & Penke, B., ápr. 2005, In : Neurobiology of Disease. 18, 3, p. 499-508 10 p.

Research output: Article

21 Citations (Scopus)

Opposite effect of Ca2+/Mg2+ ions on the aggregation of native and precursor-derived Aβ42

Bogár, F., Simon, D., Bozsó, Z., Janáky, T., Veszelka, S., Tóth, A. E., Deli, M. A., Borics, A., Násztor, Z., Gyebrovszki, A., Penke, B. & Fülöp, L., dec. 1 2015, In : Structural Chemistry. 26, 5-6, p. 1389-1403 15 p.

Research output: Article

2 Citations (Scopus)

Non-fibrillar β-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors

Shemer, I., Holmgren, C., Min, R., Fülöp, L., Zilberter, M., Sousa, K. M., Farkas, T., Härtig, W., Penke, B., Burnashev, N., Tanila, H., Zilberter, Y. & Harkany, T., ápr. 1 2006, In : European Journal of Neuroscience. 23, 8, p. 2035-2047 13 p.

Research output: Article

62 Citations (Scopus)

Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier

Mészáros, M., Porkoláb, G., Kiss, L., Pilbat, A. M., Kóta, Z., Kupihár, Z., Kéri, A., Galbács, G., Siklós, L., Tóth, A., Fülöp, L., Csete, M., Sipos, Á., Hülper, P., Sipos, P., Páli, T., Rákhely, G., Szabó-Révész, P., Deli, M. A. & Veszelka, S., okt. 15 2018, In : European Journal of Pharmaceutical Sciences. 123, p. 228-240 13 p.

Research output: Article

8 Citations (Scopus)

New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design

Gutierrez, L. J., Angelina, E., Gyebrovszki, A., Fülöp, L., Peruchena, N., Baldoni, H. A., Penke, B. & Enriz, R. D., jan. 25 2017, In : Journal of Biomolecular Structure and Dynamics. 35, 2, p. 413-426 14 p.

Research output: Article

10 Citations (Scopus)

Mechanisms Associated with Type 2 Diabetes as a Risk Factor for Alzheimer-Related Pathology

Su, M., Naderi, K., Samson, N., Youssef, I., Fülöp, L., Bozso, Z., Laroche, S., Delatour, B. & Davis, S., aug. 15 2019, In : Molecular Neurobiology. 56, 8, p. 5815-5834 20 p.

Research output: Article

4 Citations (Scopus)
5 Citations (Scopus)

Key peptides and proteins in alzheimer’s disease

Penke, B., Bogár, F., Paragi, G., Gera, J. & Fülöp, L., jan. 1 2019, In : Current Protein and Peptide Science. 20, 6, p. 577-599 23 p.

Research output: Review article

5 Citations (Scopus)

In vitro model of neurotoxicity of Aβ 1-42 and neuroprotection by a pentapeptide: Irreversible events during the first hour

Datki, Z., Papp, R., Zádori, D., Soós, K., Fülöp, L., Juhász, A., Laskay, G., Hetényi, C., Mihalik, E., Zarándi, M. & Penke, B., dec. 1 2004, In : Neurobiology of Disease. 17, 3, p. 507-515 9 p.

Research output: Article

52 Citations (Scopus)

Intranasal delivery of human β-amyloid peptide in rats: Effective brain targeting

Sipos, E., Kurunczi, A., Fehér, A., Penke, Z., Fülöp, L., Kasza, Á., Horváth, J., Horvát, S., Veszelka, S., Balogh, G., Kürti, L., Eros, I., Szabó-Révész, P., Párducz, Á., Penke, B. & Deli, M. A., ápr. 1 2010, In : Cellular and Molecular Neurobiology. 30, 3, p. 405-413 9 p.

Research output: Article

23 Citations (Scopus)

IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology

Liu, Y., Liu, X., Hao, W., Decker, Y., Schomburg, R., Fülöp, L., Pasparakis, M., Menger, M. D. & Fassbender, K., szept. 24 2014, In : Journal of Neuroscience. 34, 39, p. 12982-12999 18 p.

Research output: Article

19 Citations (Scopus)

Identification of synaptic plasma membrane proteins co-precipitated with fibrillar β-amyloid peptide

Verdier, Y., Huszár, E., Penke, B., Penke, Z., Woffendin, G., Scigelova, M., Fülöp, L., Szucs, M., Medzihradszky, K. & Janaky, T., aug. 1 2005, In : Journal of neurochemistry. 94, 3, p. 617-628 12 p.

Research output: Article

22 Citations (Scopus)
30 Citations (Scopus)

GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome

Milenkovic, I., Stojanovic, T., Aronica, E., Fülöp, L., Bozsó, Z., Máté, Z., Yanagawa, Y., Adle-Biassette, H., Lubec, G., Szabó, G., Harkany, T., Kovács, G. G. & Keimpema, E., ápr. 1 2018, In : Brain Structure and Function. 223, 3, p. 1501-1518 18 p.

Research output: Article

2 Citations (Scopus)
99 Citations (Scopus)

Fibrillar Aβ1-42enhances NMDA receptor sensitivity via the integrin signaling pathway

Juhász, G., Barkóczi, B., Vass, G., Datki, Z., Hunya, Á., Fülöp, L., Budai, D., Penke, B. & Szegedi, V., jan. 1 2010, In : Journal of Alzheimer's Disease. 19, 3, p. 1055-1067 13 p.

Research output: Article

14 Citations (Scopus)
25 Citations (Scopus)

Exceptional in vivo catabolism of neurodegeneration-related aggregates

Datki, Z., Olah, Z., Hortobagyi, T., Macsai, L., Zsuga, K., Fulop, L., Bozso, Z., Galik, B., Acs, E., Foldi, A., Szarvas, A. & Kalman, J., jan. 1 2018, In : Zoological Letters. 4, 1, 6.

Research output: Article

3 Citations (Scopus)

Enhanced G-protein activation by a mixture of Aβ(25-35), Aβ(1-40/42) and zinc

Molnár, Z., Kovács, P., Laczkó, I., Soós, K., Fülöp, L., Penket, B. & Lengyel, I., jún. 1 2004, In : Journal of neurochemistry. 89, 5, p. 1215-1223 9 p.

Research output: Article

8 Citations (Scopus)

Endomorphin-2, an endogenous tetrapeptide, protects against Aβ1-42 in vitro and in vivo

Szegedi, V., Juhá, G., Rózsa, É., Juhász-Vedres, G., Datki, Z., Fülöp, L., Bozsó, Z., Lakatos, A., Laczkó, I., Farkas, T., Kis, Z., Tóth, G., Soós, K., Zarándi, M., Budai, D., Toldi, J. & Penke, B., jún. 1 2006, In : FASEB Journal. 20, 8, p. E324-E333

Research output: Article

21 Citations (Scopus)
Open Access
101 Citations (Scopus)

Effect of nanogold particles on coupled plasmon resonance on biomolecule covered prepatterned multilayers

Sipos, Á., Tóháti, H., Mathesz, A., Szalai, A., Budai, J., Deli, M. A., Fülöp, L., Köházi-Kis, A., Csete, M. & Bor, Z., jún. 1 2010, In : Sensor Letters. 8, 3, p. 512-520 9 p.

Research output: Article

2 Citations (Scopus)
Open Access
6 Citations (Scopus)

Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit

Veszelka, S., Tóth, A. E., Walter, F. R., Datki, Z., Mózes, E., Fülöp, L., Bozsó, Z., Hellinger, É., Vastag, M., Orsolits, B., Környei, Z., Penke, B. & Deli, M. A., 2013, In : Journal of Alzheimer's Disease. 36, 3, p. 487-501 15 p.

Research output: Article

35 Citations (Scopus)

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease

Zilberter, M., Ivanov, A., Ziyatdinova, S., Mukhtarov, M., Malkov, A., Alpár, A., Tortoriello, G., Botting, C. H., Fülöp, L., Osypov, A. A., Pitkänen, A., Tanila, H., Harkany, T. & Zilberter, Y., ápr. 1 2013, In : Journal of neurochemistry. 125, 1, p. 157-171 15 p.

Research output: Article

38 Citations (Scopus)

Controlled in situ preparation of Aβ(1-42) oligomers from the isopeptide "iso-Aβ(1-42)", physicochemical and biological characterization

Bozso, Z., Penke, B., Simon, D., Laczkó, I., Juhász, G., Szegedi, V., Kasza, Á., Soós, K., Hetényi, A., Wéber, E., Tóháti, H., Csete, M., Zarándi, M. & Fülöp, L., febr. 1 2010, In : Peptides. 31, 2, p. 248-256 9 p.

Research output: Article

35 Citations (Scopus)

Conformational dynamics of titin PEVK explored with FRET spectroscopy

Huber, T., Grama, L., Hetényi, C., Schay, G., Fülöp, L., Penke, B. & Kellermayer, M. S. Z., okt. 3 2012, In : Biophysical journal. 103, 7, p. 1480-1489 10 p.

Research output: Article

7 Citations (Scopus)
22 Citations (Scopus)

Characterization of the interaction between Aβ 1-42 and glyceraldehyde phosphodehydrogenase

Verdier, Y., Földi, I., Sergeant, N., Fülöp, L., Penke, Z., Janáky, T., Szücs, M. & Penke, B., jún. 1 2008, In : Journal of Peptide Science. 14, 6, p. 755-762 8 p.

Research output: Article

22 Citations (Scopus)
53 Citations (Scopus)

Biotin and glutathione targeting of solid nanoparticles to cross human brain endothelial cells

Veszelka, S., Mészáros, M., Kiss, L., Kóta, Z., Páli, T., Hoyk, Z., Bozsó, Z., Fülöp, L., Tóth, A., Rákhely, G. & Deli, M. A., aug. 1 2017, In : Current pharmaceutical design. 23, 28, p. 4198-4205 8 p.

Research output: Article

5 Citations (Scopus)
16 Citations (Scopus)

Amyloid β-induced neuronal hyperexcitability triggers progressive epilepsy

Minkeviciene, R., Rheims, S., Dobszay, M. B., Zilberter, M., Hartikainen, J., Fülöp, L., Penke, B., Zilberter, Y., Harkany, T., Pitkänen, A. & Tanila, H., márc. 18 2009, In : Journal of Neuroscience. 29, 11, p. 3453-3462 10 p.

Research output: Article

324 Citations (Scopus)