• 558 Citations
  • 13 h-Index
20012018
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Research Output 2001 2018

  • 558 Citations
  • 13 h-Index
  • 29 Article
  • 1 Chapter
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Article
2018
2 Citations (Scopus)
Polyurethanes
Shape memory effect
Recovery
Stress-strain curves
Oligomers
6 Citations (Scopus)

Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-D-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors

Kyriakis, E., Solovou, T. G. A., Kun, S., Czifrák, K., Szőcs, B., Juhász, L., Bokor, É., Stravodimos, G. A., Kantsadi, A. L., Chatzileontiadou, D. S. M., Skamnaki, V. T., Somsák, L. & Leonidas, D. D., ápr. 1 2018, In : Bioorganic Chemistry. 77, p. 485-493 9 p.

Research output: Article

Glycogen Phosphorylase
Liver Glycogen
Catalytic Domain
Imidazoles
X ray crystallography
2016
11 Citations (Scopus)
diisocyanates
Polycaprolactone
Polyurethanes
bismaleimide
Shape memory effect
11 Citations (Scopus)
Polyurethanes
Shape memory effect
Swelling
Chemical bonds
Dynamic mechanical analysis
2015
6 Citations (Scopus)
Dynamic mechanical analysis
Shape memory effect
Polymers
Intelligent materials
Viscoelasticity
7 Citations (Scopus)
Ketones
Bromides
Derivatives
Sorbitol
Glycogen
12 Citations (Scopus)
High performance liquid chromatography
Mass spectrometry
Alcohols
Kinetics
Toluene 2,4-Diisocyanate
2014
6 Citations (Scopus)

Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: Synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methods

Czifrák, K., Páhi, A., Deák, S., Kiss-Szikszai, A., Kövér, K., Docsa, T., Gergely, P., Alexacou, K. M., Papakonstantinou, M., Leonidas, D. D., Zographos, S. E., Chrysina, E. D. & Somsák, L., aug. 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 15, p. 4028-4041 14 p.

Research output: Article

Phosphorylase b
Enzyme inhibition
Glycogen Phosphorylase
Enzyme kinetics
Muscle
32 Citations (Scopus)

New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1,2,4-triazoles, nanomolar inhibitors of glycogen phosphorylase

Kun, S., Bokor, É., Varga, G., Szocs, B., Páhi, A., Czifrák, K., Tóth, M., Juhász, L., Docsa, T., Gergely, P. & Somsák, L., ápr. 9 2014, In : European Journal of Medicinal Chemistry. 76, p. 567-579 13 p.

Research output: Article

Glycogen Phosphorylase
Phosphorylase b
Enzyme kinetics
Hydrogenation
Transesterification
6 Citations (Scopus)
diisocyanates
Poloxamer
Polyurethanes
Shape memory effect
methylene
13 Citations (Scopus)

Synthesis of C-xylopyranosyl- and xylopyranosylidene-spiro-heterocycles as potential inhibitors of glycogen phosphorylase

Somsák, L., Bokor, É., Czibere, B., Czifrák, K., Koppány, C., Kulcsár, L., Kun, S., Szilágyi, E., Tóth, M., Docsa, T. & Gergely, P., nov. 18 2014, In : Carbohydrate Research. 399, p. 38-48 11 p.

Research output: Article

Glycogen Phosphorylase
Nitriles
Cyanides
Oxides
Phosphorylase b
2013
18 Citations (Scopus)
formic acid
Chlorides
Acylation
Acids
Glycogen Phosphorylase
2011
41 Citations (Scopus)
Thiohydantoins
Glycogen Phosphorylase
Streptozocin
Glycogen
Metabolism
6 Citations (Scopus)
Formamides
Oligopeptides
Nitriles
Amino Acids
Dipeptides
2010
18 Citations (Scopus)
Pentacyclic Triterpenes
Glycogen Phosphorylase
Azides
Glucose
Enzymes
2009
39 Citations (Scopus)

Glucose-based spiro-heterocycles as potent inhibitors of glycogen phosphorylase

Nagy, V., Benltifa, M., Vidal, S., Berzsényi, E., Teilhet, C., Czifrák, K., Batta, G., Docsa, T., Gergely, P., Somsák, L. & Praly, J. P., aug. 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 15, p. 5696-5707 12 p.

Research output: Article

Glycogen Phosphorylase
Cyclization
Aromatization
Glucose
Sulfur
11 Citations (Scopus)
Glycogen Phosphorylase
Acylation
Azides
Structure-Activity Relationship
Carboxylic Acids
15 Citations (Scopus)
Halogenation
Sulfonamides
Propionates
Sulfones
sulfoxide
5 Citations (Scopus)
Phosphorylase b
Glycogen Phosphorylase
Glycosides
Acetone
Phenol
2008
24 Citations (Scopus)

Assessment of synthetic methods for the preparation of N-β-d-glucopyranosyl-N′-substituted ureas, -thioureas and related compounds

Somsák, L., Felföldi, N., Kónya, B., Hüse, C., Telepó, K., Bokor, É. & Czifrák, K., aug. 11 2008, In : Carbohydrate Research. 343, 12, p. 2083-2093 11 p.

Research output: Article

Thiourea
Isocyanates
Urea
Derivatives
Acylation
120 Citations (Scopus)

New inhibitors of glycogen phosphorylase as potential antidiabetic agents

Somsák, L., Czifrák, K., Tóth, M., Bokor, É., Chrysina, E. D., Alexacou, K. M., Hayes, J. M., Tiraidis, C., Lazoura, E., Leonidas, D. D., Zographos, S. E. & Oikonomakos, N. G., dec. 2008, In : Current Medicinal Chemistry. 15, 28, p. 2933-2983 51 p.

Research output: Article

Glycogen Phosphorylase
Enzyme Inhibitors
Hypoglycemic Agents
Ligands
Binding Sites
30 Citations (Scopus)
Phosphorylase b
Glycogen Phosphorylase
Hypoglycemic Agents
Muscle
Rabbits
2006
18 Citations (Scopus)
Glycogen Phosphorylase
Dicarboxylic Acids
Phosphorylase b
Azides
Anhydrides
2005
22 Citations (Scopus)
Sugar Acids
sugars
Sugars
Peptides
peptides
18 Citations (Scopus)
formic acid
Glycogen Phosphorylase
Derivatives
Acids
Amides
2002
10 Citations (Scopus)
Monosaccharides
Carbon Tetrachloride
Halogenation
Carbohydrates
Health
2001
13 Citations (Scopus)
Thiadiazoles
Dithionite
Hydrogen Sulfide
Methylene Chloride
Cyanides
10 Citations (Scopus)
Cyanides
cyanides
preparation
Thiocyanates
Equilibrium constants