• 554 Citations
  • 15 h-Index
20042019
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Research Output 2004 2019

  • 554 Citations
  • 15 h-Index
  • 29 Article
  • 1 Conference contribution
2019

Linking PANSS negative symptom scores with the Clinical Global Impressions Scale: understanding negative symptom scores in schizophrenia

Leucht, S., Barabássy, Á., Laszlovszky, I., Szatmári, B., Acsai, K., Szalai, E., Harsányi, J., Earley, W. & Németh, G., jan. 1 2019, In : Neuropsychopharmacology.

Research output: Article

Open Access
Schizophrenia
Risperidone
Depression
Population

Protective effects of glycerol and xylitol in keratinocytes exposed to hyperosmotic stress

Szél, E., Danis, J., Sőrés, E., Tóth, D., Korponyai, C., Degovics, D., Prorok, J., Acsai, K., Dikstein, S., Kemény, L. & Erős, G., jan. 1 2019, In : Clinical, Cosmetic and Investigational Dermatology. 12, p. 323-331 9 p.

Research output: Article

Open Access
Xylitol
Keratinocytes
Glycerol
Osmotic Pressure
Interleukin-1

The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors

Fleischhacker, W., Galderisi, S., Laszlovszky, I., Szatmári, B., Barabássy, Á., Acsai, K., Szalai, E., Harsányi, J., Earley, W., Patel, M. & Németh, G., máj. 1 2019, In : European Psychiatry. 58, p. 1-9 9 p.

Research output: Article

Open Access
Risperidone
Schizophrenia
Serotonin 5-HT1 Receptor Agonists
cariprazine
Cognition
2018

Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes

Oravecz, K., Kormos, A., Gruber, A., Márton, Z., Kohajda, Z., Mirzaei, L., Jost, N., Levijoki, J., Pollesello, P., Koskelainen, T., Otsomaa, L., Tóth, A., Papp, J., Nánási, P., Antoons, G., Varró, A., Acsai, K. & Nagy, N., jan. 5 2018, In : European Journal of Pharmacology. 818, p. 278-286 9 p.

Research output: Article

Sarcoplasmic Reticulum
Muscle Cells
Canidae
Myocardium
Treatment Failure
2016
4 Citations (Scopus)

Block of Na+/Ca2+ exchanger by SEA0400 in human right atrial preparations from patients in sinus rhythm and in atrial fibrillation

Christ, T., Kovács, P. P., Acsai, K., Knaut, M., Eschenhagen, T., Jost, N., Varró, A., Wettwer, E. & Ravens, U., okt. 5 2016, In : European Journal of Pharmacology. 788, p. 286-293 8 p.

Research output: Article

Atrial Fibrillation
Cardiac Myocytes
Action Potentials
Architectural Accessibility
Microelectrodes
2 Citations (Scopus)
Sodium-Calcium Exchanger
Action Potentials
Canidae
Guinea Pigs
Cardiac Arrhythmias
2015
6 Citations (Scopus)
Dantrolene
Ryanodine Receptor Calcium Release Channel
Anti-Arrhythmia Agents
Drug Delivery Systems
Pharmacology
13 Citations (Scopus)
Myocardial Reperfusion
Sodium-Hydrogen Antiporter
Cardiac Arrhythmias
Reperfusion
Premature Cardiac Complexes
6 Citations (Scopus)

Lack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation

Ujhelly, O., Szabo, V., Kovacs, G., Vajda, F., Mallok, S., Prorok, J., Acsai, K., Hegedűs, Z., Krebs, S., Dinnyés, A. & Pirity, M., szept. 15 2015, In : Stem Cells and Development. 24, 18, p. 2193-2205 13 p.

Research output: Article

Carrier Proteins
Embryonic Stem Cells
Cardiac Myocytes
Polycomb Repressive Complex 1
Mouse Embryonic Stem Cells
1 Citation (Scopus)
Ryanodine Receptor Calcium Release Channel
Cardiac Arrhythmias
Cardiovascular Diseases
Pharmacology
Homeostasis
2014
6 Citations (Scopus)

Efficacy of selective NCX inhibition by ORM-10103 during simulated ischemia/reperfusion

Kormos, A., Nagy, N., Acsai, K., Váczi, K., Ágoston, S., Pollesello, P., Levijoki, J., Szentandrássy, N., Papp, J., Varró, A. & Tóth, A., okt. 5 2014, In : European Journal of Pharmacology. 740, p. 539-551 13 p.

Research output: Article

Reperfusion
Action Potentials
Ischemia
NAD
Cardiac Myocytes
21 Citations (Scopus)

Selective Na +/ Ca 2+ exchanger inhibition prevents Ca 2+ overload-induced triggered arrhythmias

Nagy, N., Kormos, A., Kohajda, Z., Szebeni, Á., Szepesi, J., Pollesello, P., Levijoki, J., Acsai, K., Virág, L., Nánási, P., Papp, J., Varró, A. & Tóth, A., 2014, In : British Journal of Pharmacology. 171, 24, p. 5665-5681 17 p.

Research output: Article

Sodium-Calcium Exchanger
Anemone
Action Potentials
Cardiac Arrhythmias
Anti-Arrhythmia Agents
2013
30 Citations (Scopus)

Combined Na+/Ca2+ exchanger and l-type calcium channel block as a potential strategy to suppress arrhythmias and maintain ventricular function

Bourgonje, V. J. A., Vos, M. A., Ozdemir, S., Doisne, N., Acsai, K., Varró, A., Sztojkov-Ivanov, A., Zupkó, I., Rauch, E., Kattner, L., Bito, V., Houtman, M., Van Der Nagel, R., Beekman, J. D., Van Veen, T. A. B., Sipido, K. R. & Antoons, G., ápr. 2013, In : Circulation: Arrhythmia and Electrophysiology. 6, 2, p. 371-379 9 p.

Research output: Article

Ventricular Function
Calcium Channels
L-Type Calcium Channels
Cardiac Arrhythmias
Torsades de Pointes
17 Citations (Scopus)
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Action Potentials
Canidae
Myocardium
Potassium
32 Citations (Scopus)

ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart

Jost, N., Nagy, N., Corici, C., Kohajda, Z., Horváth, A., Acsai, K., Biliczki, P., Levijoki, J., Pollesello, P., Koskelainen, T., Otsomaa, L., Tóth, A., Papp, J., Varró, A. & Virág, L., okt. 2013, In : British Journal of Pharmacology. 170, 4, p. 768-778 11 p.

Research output: Article

Canidae
Action Potentials
Guinea Pigs
Papillary Muscles
Microelectrodes
9 Citations (Scopus)

T-tubule remodelling and ryanodine receptor organization modulate sodium-calcium exchange

Sipido, K. R., Acsai, K., Antoons, G., Bito, V. & MacQuaide, N., 2013, Advances in Experimental Medicine and Biology. Vol. 961. p. 375-383 9 p. (Advances in Experimental Medicine and Biology; vol. 961).

Research output: Conference contribution

Ryanodine Receptor Calcium Release Channel
Sarcoplasmic Reticulum
Sodium
Calcium
Excitation Contraction Coupling
2012
7 Citations (Scopus)

Data-based theoretical identification of subcellular calcium compartments and estimation of calcium dynamics in cardiac myocytes

Livshitz, L., Acsai, K., Antoons, G., Sipido, K. & Rudy, Y., szept. 2012, In : Journal of Physiology. 590, 18, p. 4423-4446 24 p.

Research output: Article

Cardiac Myocytes
Cats
Calcium
Sarcoplasmic Reticulum
Sarcolemma
2011
44 Citations (Scopus)

Microdomain [Ca2+] near ryanodine receptors as reported by L-type Ca2+ and Na+/Ca2+ exchange currents

Acsai, K., Antoons, G., Livshitz, L., Rudy, Y. & Sipido, K. R., máj. 2011, In : Journal of Physiology. 589, 10, p. 2569-2583 15 p.

Research output: Article

Ryanodine Receptor Calcium Release Channel
Sarcoplasmic Reticulum
Muscle Cells
Calibration
Swine
2009
26 Citations (Scopus)
Muscle Cells
Action Potentials
Canidae
Architectural Accessibility
Potassium
59 Citations (Scopus)

Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?

Nagy, N., Szűts, V., Horváth, Z., Seprényi, G., Farkas, A. S., Acsai, K., Prorok, J., Bitay, M., Kun, A., Pataricza, J., Papp, J., Nánási, P., Varró, A. & Tóth, A., nov. 2009, In : Journal of Molecular and Cellular Cardiology. 47, 5, p. 656-663 8 p.

Research output: Article

Small-Conductance Calcium-Activated Potassium Channels
Action Potentials
Apamin
pamidronate
Cardiac Myocytes
20 Citations (Scopus)
Action Potentials
Potassium
Veratrine
Dogs
Architectural Accessibility
2008
21 Citations (Scopus)
Sodium-Calcium Exchanger
Myocardial Contraction
Rabbits
Action Potentials
Blood Pressure
20 Citations (Scopus)
Cardiac Myocytes
Canidae
Muscle Cells
Sarcoplasmic Reticulum
Caffeine
2007
19 Citations (Scopus)
Muscle Cells
Fura-2
Sarcoplasmic Reticulum
Fluorescent Dyes
Pharmacology
2006
16 Citations (Scopus)
Torsades de Pointes
Methoxamine
Adrenergic Receptors
Rabbits
R Factors
2005
3 Citations (Scopus)

Cellular electrophysiological effect of terikalant in the dog heart

Biliczki, P., Acsai, K., Virág, L., Tálosi, L., Jost, N., Biliczki, A., Papp, J. & Varró, A., márc. 14 2005, In : European Journal of Pharmacology. 510, 3, p. 161-166 6 p.

Research output: Article

Action Potentials
Dogs
Purkinje Fibers
Papillary Muscles
Anti-Arrhythmia Agents
86 Citations (Scopus)
Cardiac Myocytes
Canidae
Patch-Clamp Techniques
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate
SEA 0400
2004
15 Citations (Scopus)
Ion Channels
Potassium Channel Blockers
Ions
Sodium-Hydrogen Antiporter
Gap Junctions
71 Citations (Scopus)
Sodium-Calcium Exchanger
Canidae
Calcium
Purkinje Fibers
Fluorometry