• 3893 Citations
  • 33 h-Index
1978 …2019

Research output per year

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Research Output

2019
4 Citations (Scopus)

Investigating KYNA production and kynurenergic manipulation on acute mouse brain slice preparations

Herédi, J., Cseh, E. K., Berkó, A. M., Veres, G., Zádori, D., Toldi, J., Kis, Z., Vécsei, L., Ono, E. & Gellért, L., márc. 2019, In : Brain Research Bulletin. 146, p. 185-191 7 p.

Research output: Article

2 Citations (Scopus)

Structural evaluation and electrophysiological effects of some kynurenic acid analogs

Fehér, E., Szatmári, I., Dudás, T., Zalatnai, A., Farkas, T., Orinczi, B. L., Fülöp, F., Vécsei, L. & Toldi, J., szept. 26 2019, In : Molecules. 24, 19, 3502.

Research output: Article

Open Access
2 Citations (Scopus)
2018

Ischemic Stroke and Kynurenines: Medicinal Chemistry Aspects

Hertelendy, P., Toldi, J., Fülöp, F. & Vécsei, L., jan. 1 2018, In : Current medicinal chemistry. 25, 42, p. 5945-5957 13 p.

Research output: Review article

2 Citations (Scopus)
2017

Astrocytic and neuronal localization of kynurenine aminotransferase-2 in the adult mouse brain

Herédi, J., Berkó, A. M., Jankovics, F., Iwamori, T., Iwamori, N., Ono, E., Horváth, S., Kis, Z., Toldi, J., Vécsei, L. & Gellért, L., máj. 1 2017, In : Brain Structure and Function. 222, 4, p. 1663-1672 10 p.

Research output: Article

14 Citations (Scopus)

Kynurenines and PACAP in migraine: Medicinal chemistry and pathogenetic aspects

Tajti, J., Szok, D., Nagy-Grócz, G., Tuka, B., Petrovics-Balog, A., Toldi, J. & Vécsei, L., jan. 1 2017, In : Current medicinal chemistry. 24, 13, p. 1332-1349 18 p.

Research output: Review article

6 Citations (Scopus)

Migraine, Neurogenic Inflammation, Drug Development - Pharmacochemical Aspects

Lukacs, M., Tajti, J., Fulop, F., Toldi, J., Edvinsson, L. & Vecsei, L., jan. 1 2017, In : Current medicinal chemistry. 24, 33, p. 3649-3665 17 p.

Research output: Review article

16 Citations (Scopus)

Systemic administration of L-kynurenine sulfate induces cerebral hypoperfusion transients in adult C57Bl/6 mice

Varga, D. P., Menyhárt, Á., Puskás, T., Bari, F., Farkas, E., Kis, Z., Vécsei, L., Toldi, J. & Gellért, L., nov. 2017, In : Microvascular Research. 114, p. 19-25 7 p.

Research output: Article

3 Citations (Scopus)
12 Citations (Scopus)
2016

Acetyl-L-carnitine restores synaptic transmission and enhances the inducibility of stable LTP after oxygen–glucose deprivation

Kocsis, K., Frank, R., Szabó, J., Knapp, L., Kis, Z., Farkas, T., Vécsei, L. & Toldi, J., szept. 22 2016, In : Neuroscience. 332, p. 203-211 9 p.

Research output: Article

7 Citations (Scopus)

Brain aging and disorders of the central nervous system: Kynurenines and drug metabolism

Török, N., Majláth, Z., Fülöp, F., Toldi, J. & Vécsei, L., jún. 1 2016, In : Current Drug Metabolism. 17, 5, p. 412-429 18 p.

Research output: Review article

13 Citations (Scopus)
3 Citations (Scopus)

Inhibitors of the kynurenine pathway as neurotherapeutics: A patent review (2012–2015)

Zádori, D., Veres, G., Szalárdy, L., Klivényi, P., Fülöp, F., Toldi, J. & Vécsei, L., júl. 2 2016, In : Expert Opinion on Therapeutic Patents. 26, 7, p. 815-832 18 p.

Research output: Review article

6 Citations (Scopus)
13 Citations (Scopus)

Memantine and kynurenic acid: Current neuropharmacological aspects

Majláth, Z., Török, N., Toldi, J. & Vécsei, L., febr. 1 2016, In : Current neuropharmacology. 14, 2, p. 200-209 10 p.

Research output: Article

13 Citations (Scopus)

Promising therapeutic agents for the treatment of Parkinson’s disease

Majláth, Z., Török, N., Toldi, J. & Vécsei, L., jún. 2 2016, In : Expert Opinion on Biological Therapy. 16, 6, p. 787-799 13 p.

Research output: Review article

3 Citations (Scopus)
20 Citations (Scopus)
2015
2 Citations (Scopus)
34 Citations (Scopus)

Chapter 15: The role of the kynurenine pathway in neurodegenerative diseases

Majláth, Z. A., Toldi, J. & Vécsei, L., jan. 1 2015, Targeting the Broadly Pathogenic Kynurenine Pathway. Springer International Publishing, p. 193-204 12 p.

Research output: Chapter

Chapter 18: The role of kynurenine pathway in pain and migraine

Majláth, Z. A., Toldi, J. & Vécsei, L., jan. 1 2015, Targeting the Broadly Pathogenic Kynurenine Pathway. Springer International Publishing, p. 233-240 8 p.

Research output: Chapter

Effect of a kynurenic acid analog on home-cage activity and body temperature in rats

Kassai, F., Kedves, R., Gyertyán, I., Tuka, B., Fülöp, F., Toldi, J., Lendvai, B. & Vécsei, L., dec. 1 2015, In : Pharmacological Reports. 67, 6, p. 1188-1192 5 p.

Research output: Article

3 Citations (Scopus)

Effect of probenecid on the pain-related behaviour and morphological markers in orofacial formalin test of the rat

Fejes-Szabó, A., Bohár, Z., Nagy-Grócz, G., Vámos, E., Tar, L., Pődör, B., Tajti, J., Toldi, J., Vécsei, L. & Párdutz, Á., márc. 1 2015, In : CNS and Neurological Disorders - Drug Targets. 14, 3, p. 350-359 10 p.

Research output: Article

4 Citations (Scopus)
15 Citations (Scopus)

Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion

Csáti, A., Edvinsson, L., Vécsei, L., Toldi, J., Fülöp, F., Tajti, J. & Warfvinge, K., dec. 1 2015, In : Journal of Headache and Pain. 16, 1, p. 1-14 14 p., 99.

Research output: Article

24 Citations (Scopus)
6 Citations (Scopus)

Systemic L-Kynurenine sulfate administration disrupts object recognition memory, alters open field behavior and decreases c-Fos immunopositivity in C57Bl/6 mice

Varga, D., Herédi, J., Kánvási, Z., Ruszka, M., Kis, Z., Ono, E., Iwamori, N., Iwamori, T., Takakuwa, H., Vécsei, L., Toldi, J. & Gellért, L., jún. 16 2015, In : Frontiers in Behavioral Neuroscience. 9, June, A157.

Research output: Article

15 Citations (Scopus)
2014

Acetyl-l-carnitine normalizes the impaired long-term potentiation and spine density in a rat model of global ischemia

Kocsis, K., Knapp, L., Gellért, L., Oláh, G., Kis, Z., Takakuwa, H., Iwamori, N., Ono, E., Toldi, J. & Farkas, T., jún. 6 2014, In : Neuroscience. 269, p. 265-272 8 p.

Research output: Article

14 Citations (Scopus)

A simple novel technique to induce short-lasting local brain ischaemia in the rat

Knapp, L., Gellért, L., Herédi, J., Kocsis, K., Oláh, G., Fuzik, J., Kis, Z., Vécsei, L., Toldi, J. & Farkas, T., aug. 2014, In : Neuropathology and Applied Neurobiology. 40, 5, p. 603-609 7 p.

Research output: Article

3 Citations (Scopus)

Glutamatergic dysfunctioning in Alzheimer's disease and related therapeutic targets

Zádori, D., Veres, G., Szalárdy, L., Klivényi, P., Toldi, J. & Vécsei, L., jan. 1 2014, In : Journal of Alzheimer's Disease. 42, p. S177-S187

Research output: Article

51 Citations (Scopus)
8 Citations (Scopus)
10 Citations (Scopus)

Neuroprotection by kynurenine metabolites

Majlath, Z., Szalardy, L., Zadori, D., Klivényi, P., Fülöp, F., Toldi, J. & Vécsei, L., jan. 1 2014, Handbook of Neurotoxicity. Springer New York, Vol. 2. p. 1403-1416 14 p.

Research output: Chapter

Neuroprotective Effect of Oxaloacetate in a Focal Brain Ischemic Model in the Rat

Knapp, L., Gellért, L., Kocsis, K., Kis, Z., Farkas, T., Vécsei, L. & Toldi, J., jan. 1 2014, In : Cellular and Molecular Neurobiology. 35, 1, p. 17-22 6 p.

Research output: Article

13 Citations (Scopus)
16 Citations (Scopus)
16 Citations (Scopus)
2013

Fundamental interstrain differences in cortical activity between Wistar and Sprague-Dawley rats during global ischemia

Fuzik, J., Gellért, L., Oláh, G., Herédi, J., Kocsis, K., Knapp, L., Nagy, D., Kincses, Z. T., Kis, Z., Farkas, T. & Toldi, J., jan. 3 2013, In : Neuroscience. 228, p. 371-381 11 p.

Research output: Article

11 Citations (Scopus)

Kynurenines in the CNS: Recent advances and new questions

Vécsei, L., Szalárdy, L., Fülöp, F. & Toldi, J., jan. 1 2013, In : Nature Reviews Drug Discovery. 12, 1, p. 64-82 19 p.

Research output: Review article

305 Citations (Scopus)

Paradox effects of kynurenines on LTP induction in the Wistar rat. An in vivo study

Demeter, I., Nagy, K., Farkas, T., Kis, Z., Kocsis, K., Knapp, L., Gellert, L., Fülöp, F., Vecsei, L. & Toldi, J., okt. 11 2013, In : Neuroscience Letters. 553, p. 138-141 4 p.

Research output: Article

8 Citations (Scopus)

Post-ischemic treatment with L-kynurenine sulfate exacerbates neuronal damage after transient middle cerebral artery occlusion

Gellért, L., Knapp, L., Németh, K., Herédi, J., Varga, D., Oláh, G., Kocsis, K., Menyhárt, Á., Kis, Z., Farkas, T., Vécsei, L. & Toldi, J., szept. 5 2013, In : Neuroscience. 247, p. 95-101 7 p.

Research output: Article

12 Citations (Scopus)
13 Citations (Scopus)

Unexpected effects of peripherally administered kynurenic acid on cortical spreading depression and related blood-brain barrier permeability

Gáspár, O., Herédi, J., Menyhárt, Á., Zsolt, C., Nagy, D., Fuzik, J., Kocsis, K., Knapp, L., Krucsó, E., Gellért, L., Kis, Z., Farkas, T., Fülöp, F., Párdutz, Á., Tajti, J., Vécsei, L. & Toldi, J., szept. 13 2013, In : Drug Design, Development and Therapy. 7, p. 981-987 7 p.

Research output: Article

26 Citations (Scopus)
2012
11 Citations (Scopus)

Behavioural studies with a newly developed neuroprotective KYNA-amide

Gellért, L., Varga, D., Ruszka, M., Toldi, J., Farkas, T., Szatmári, I., Fülöp, F., Vécsei, L. & Kis, Z., febr. 1 2012, In : Journal of neural transmission. 119, 2, p. 165-172 8 p.

Research output: Article

15 Citations (Scopus)

Is Ro 61-8048 a potential fast-acting antidepressant?

Szabó, N., Kincses, Z. T., Toldi, J. & Vécsei, L., ápr. 15 2012, In : Journal of the Neurological Sciences. 315, 1-2, p. 181-182 2 p.

Research output: Letter

Kynurenines and headache

Párdutz, Á., Fejes, A., Bohár, Z., Tar, L., Toldi, J. & Vécsei, L., febr. 1 2012, In : Journal of neural transmission. 119, 2, p. 285-296 12 p.

Research output: Review article

20 Citations (Scopus)

Kynurenines in Parkinson's disease: Therapeutic perspectives

Zádori, D., Klivényi, P., Toldi, J., Fülöp, F. & Vécsei, L., febr. 1 2012, In : Journal of neural transmission. 119, 2, p. 275-283 9 p.

Research output: Review article

24 Citations (Scopus)
28 Citations (Scopus)
54 Citations (Scopus)