• 6679 Citations
  • 42 h-Index
1978 …2019

Research output per year

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Research Output

2019

Acute physiological changes caused by complement activators and amphotericin b-containing liposomes in mice

Őrfi, E., Mészáros, T., Hennies, M., Fülöp, T., Dézsi, L., Nardocci, A., Rosivall, L., Hamar, P., Neun, B. W., Dobrovolskaia, M. A., Szebeni, J. & Szénási, G., jan. 1 2019, In : International journal of nanomedicine. 14, p. 1563-1573 11 p.

Research output: Article

Open Access
5 Citations (Scopus)
Open Access
1 Citation (Scopus)

Doxebo (doxorubicin-free Doxil-like liposomes) is safe to use as a pre-treatment to prevent infusion reactions to PEGylated nanodrugs

Bavli, Y., Winkler, I., Chen, B. M., Roffler, S., Cohen, R., Szebeni, J. & Barenholz, Y., júl. 28 2019, In : Journal of Controlled Release. 306, p. 138-148 11 p.

Research output: Article

2 Citations (Scopus)

Liposome-induced hypersensitivity reactions: Risk reduction by design of safe infusion protocols in pigs

Fülöp, T., Kozma, G. T., Vashegyi, I., Mészáros, T., Rosivall, L., Urbanics, R., Storm, G., Metselaar, J. M. & Szebeni, J., szept. 10 2019, In : Journal of Controlled Release. 309, p. 333-338 6 p.

Research output: Article

Open Access
3 Citations (Scopus)

PEGylated liposomes: immunological responses

Mohamed, M., Abu Lila, A. S., Shimizu, T., Alaaeldin, E., Hussein, A., Sarhan, H. A., Szebeni, J. & Ishida, T., dec. 31 2019, In : Science and Technology of Advanced Materials. 20, 1, p. 710-724 15 p.

Research output: Review article

Open Access
13 Citations (Scopus)

Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions

Kozma, G. T., Mészáros, T., Vashegyi, I., Fülöp, T., Örfi, E., Dézsi, L., Rosivall, L., Bavli, Y., Urbanics, R., Mollnes, T. E., Barenholz, Y. & Szebeni, J., aug. 27 2019, In : ACS Nano. 13, 8, p. 9315-9324 10 p.

Research output: Article

5 Citations (Scopus)
2018

Animal models for analysis of immunological responses to nanomaterials: Challenges and considerations

Zamboni, W. C., Szebeni, J., Kozlov, S. V., Lucas, A. T., Piscitelli, J. A. & Dobrovolskaia, M. A., nov. 1 2018, In : Advanced Drug Delivery Reviews. 136-137, p. 82-96 15 p.

Research output: Review article

10 Citations (Scopus)

Anticoagulants influence the performance of in vitro assays intended for characterization of nanotechnology-based formulations

Cedrone, E., Neun, B. W., Rodriguez, J., Vermilya, A., Clogston, J. D., McNeil, S. E., Barenholz, Y., Szebeni, J. & Dobrovolskaia, M. A., jan. 1 2018, In : Molecules. 23, 1, 12.

Research output: Article

6 Citations (Scopus)
11 Citations (Scopus)

Dextran-coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging: Evaluation of size-dependent imaging properties, storage stability and safety

Unterweger, H., Dézsi, L., Matuszak, J., Janko, C., Poettler, M., Jordan, J., Bäuerle, T., Szebeni, J., Fey, T., Boccaccini, A. R., Alexiou, C. & Cicha, I., márc. 28 2018, In : International journal of nanomedicine. 13, p. 1899-1915 17 p.

Research output: Article

22 Citations (Scopus)

From design to the clinic: Practical guidelines for translating cardiovascular nanomedicine

Cicha, I., Chauvierre, C., Texier, I., Cabella, C., Metselaar, J. M., Szebeni, J., Dézsi, L., Alexiou, C., Rouzet, F., Storm, G., Stroes, E., Bruce, D., MacRitchie, N., Maffia, P. & Letourneur, D., jan. 1 2018, In : Cardiovascular research. 114, 13, p. 1714-1727 14 p.

Research output: Review article

11 Citations (Scopus)
7 Citations (Scopus)
11 Citations (Scopus)

Roadmap and strategy for overcoming infusion reactions to nanomedicines

Szebeni, J., Simberg, D., González-Fernández, Á., Barenholz, Y. & Dobrovolskaia, M. A., dec. 1 2018, In : Nature Nanotechnology. 13, 12, p. 1100-1108 9 p.

Research output: Review article

25 Citations (Scopus)

Theranostic Imaging May Vaccinate against the Therapeutic Benefit of Long Circulating PEGylated Liposomes and Change Cargo Pharmacokinetics

Børresen, B., Henriksen, J. R., Clergeaud, G., Jørgensen, J. S., Melander, F., Elema, D. R., Szebeni, J., Engelholm, S. A., Kristensen, A. T., Kjær, A., Andresen, T. L. & Hansen, A. E., nov. 27 2018, In : ACS Nano. 12, 11, p. 11386-11398 13 p.

Research output: Article

13 Citations (Scopus)

Understanding the role of anti-PEG antibodies in the complement activation by Doxil in vitro

Neun, B. W., Barenholz, Y., Szebeni, J. & Dobrovolskaia, M. A., jan. 1 2018, In : Molecules. 23, 7, 1700.

Research output: Article

10 Citations (Scopus)
2017

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes

Wibroe, P. P., Anselmo, A. C., Nilsson, P. H., Sarode, A., Gupta, V., Urbanics, R., Szebeni, J., Hunter, A. C., Mitragotri, S., Mollnes, T. E. & Moghimi, S. M., jún. 6 2017, In : Nature Nanotechnology. 12, 6, p. 589-594 6 p.

Research output: Article

65 Citations (Scopus)

Immunological response to nitroglycerin-loaded shear-responsive liposomes in vitro and in vivo

Buscema, M., Matviykiv, S., Mészáros, T., Gerganova, G., Weinberger, A., Mettal, U., Mueller, D., Neuhaus, F., Stalder, E., Ishikawa, T., Urbanics, R., Saxer, T., Pfohl, T., Szebeni, J., Zumbuehl, A. & Müller, B., okt. 28 2017, In : Journal of Controlled Release. 264, p. 14-23 10 p.

Research output: Article

7 Citations (Scopus)

Liposomes: Bio-inspired nano-containers for physically triggered targeted drug delivery

Matviykiv, S., Buscema, M., Mészáros, T., Gerganova, G., Pfohl, T., Zumbühl, A., Szebeni, J. & Müller, B., jan. 1 2017, Bioinspiration, Biomimetics, and Bioreplication 2017. Lakhtakia, A., Knez, M. & Martin-Palma, R. J. (eds.). SPIE, 101620A. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 10162).

Research output: Conference contribution

1 Citation (Scopus)

Non-immunogenic dextran-coated superparamagnetic iron oxide nanoparticles: A biocompatible, size-tunable contrast agent for magnetic resonance imaging

Unterweger, H., Janko, C., Schwarz, M., Dézsi, L., Urbanics, R., Matuszak, J., Őrfi, E., Fülöp, T., Bäuerle, T., Szebeni, J., Journé, C., Boccaccini, A. R., Alexiou, C., Lyer, S. & Cicha, I., júl. 24 2017, In : International journal of nanomedicine. 12, p. 5223-5238 16 p.

Research output: Article

28 Citations (Scopus)

Peptide-based Vaccines Derived from FceRI beta subunit can reduce allergic response in mice model

Zare, A., Pourfathollah, A. A., Pourpak, Z., Szebeni, J., Ghaffari, S. M. R. & Kardar, G. A., aug. 2017, In : Iranian Journal of Allergy, Asthma and Immunology. 16, 4, p. 289-297 9 p.

Research output: Review article

1 Citation (Scopus)

The role of thromboxane A2 in complement activation-related pseudoallergy

Fülöp, T. G., Metselaar, J. M., Storm, G. & Szebeni, J., ápr. 1 2017, In : European Journal of Nanomedicine. 9, 2, p. 59-67 9 p.

Research output: Review article

2016
5 Citations (Scopus)
7 Citations (Scopus)

Challenges and Risks of Nanotechnology in Medicine: An Immunologist's Point of View

Szebeni, J., szept. 19 2016, Nanoscience and Nanotechnology for Human Health. wiley, p. 97-123 27 p.

Research output: Chapter

1 Citation (Scopus)
29 Citations (Scopus)

Complement activation: A capricious immune barrier to the clinical use of nanomedicines

Szebeni, J., máj. 2 2016, Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety, and Risk. Pan Stanford Publishing Pte. Ltd., Vol. 2. p. 845-871 27 p.

Research output: Chapter

1 Citation (Scopus)

Factor H inhibits complement activation induced by liposomal and micellar drugs and the therapeutic antibody rituximab in vitro

Mészáros, T., Csincsi, Á. I., Uzonyi, B., Hebecker, M., Fülöp, T. G., Erdei, A., Szebeni, J. & Józsi, M., máj. 1 2016, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 12, 4, p. 1023-1031 9 p.

Research output: Article

13 Citations (Scopus)

Liposomal doxorubicin: the good, the bad and the not-so-ugly

Szebeni, J., Fülöp, T., Dézsi, L., Metselaar, B. & Storm, G., ápr. 26 2016, (Accepted/In press) In : Journal of Drug Targeting. p. 1-3 3 p.

Research output: Article

7 Citations (Scopus)

Nanoparticles for intravascular applications: Pcharacterization and cytotoxicity testing

Matuszak, J., Baumgartner, J., Zaloga, J., Juenet, M., Da Silva, A. E., Franke, D., Almer, G., Texier, I., Faivre, D., Metselaar, J. M., Navarro, F. P., Chauvierre, C., Prassl, R., Dézsi, L., Urbanics, R., Alexiou, C., Mangge, H., Szebeni, J., Letourneur, D. & Cicha, I., márc. 2016, In : Nanomedicine. 11, 6, p. 597-616 20 p.

Research output: Article

31 Citations (Scopus)

Surprising lack of liposome-induced complement activation by artificial 1,3-diamidophospholipids in vitro

Bugna, S., Buscema, M., Matviykiv, S., Urbanics, R., Weinberger, A., Meszaros, T., Szebeni, J., Zumbuehl, A., Saxer, T. & Müller, B., ápr. 1 2016, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 12, 3, p. 845-849 5 p.

Research output: Article

13 Citations (Scopus)
12 Citations (Scopus)
2015

Blood cell changes in complement activation-related pseudoallergy

Patkó, Z. & Szebeni, J., jún. 1 2015, In : European Journal of Nanomedicine. 7, 3, p. 233-244 12 p.

Research output: Review article

6 Citations (Scopus)
46 Citations (Scopus)

Exosomes: Potential model for complement-stealth delivery systems

Milosevits, G., Szebeni, J. & Krol, S., jún. 1 2015, In : European Journal of Nanomedicine. 7, 3, p. 207-218 12 p.

Research output: Review article

3 Citations (Scopus)

Hypersensitivity to intravenous iron: Classification, terminology, mechanisms and management

Szebeni, J., Fishbane, S., Hedenus, M., Howaldt, S., Locatelli, F., Patni, S., Rampton, D., Weiss, G. & Folkersen, J., nov. 1 2015, In : British journal of pharmacology. 172, 21, p. 5025-5036 12 p.

Research output: Review article

48 Citations (Scopus)
18 Citations (Scopus)

Membrane attack complex formation on a supported lipid bilayer: Initial steps towards a CARPA predictor nanodevice

Yorulmaz, S., Tabaei, S. R., Kim, M., Seo, J., Hunziker, W., Szebeni, J. & Cho, N. J., jún. 1 2015, In : European Journal of Nanomedicine. 7, 3, p. 245-255 11 p.

Research output: Article

7 Citations (Scopus)
4 Citations (Scopus)

Pulmonary intravascular macrophages: Prime suspects as cellular mediators of porcine CARPA

Csukás, D., Urbanics, R., Wéber, G., Rosivall, L. & Szebeni, J., jan. 1 2015, In : European Journal of Nanomedicine. 7, 1, p. 27-36 10 p.

Research output: Review article

12 Citations (Scopus)
4 Citations (Scopus)
3 Citations (Scopus)
8 Citations (Scopus)
2014
120 Citations (Scopus)

Features of complement activation-related pseudoallergy to liposomes with different surface charge and PEGylation: Comparison of the porcine and rat responses

Dézsi, L., Fülöp, T., Mészáros, T., Szénási, G., Urbanics, R., Vázsonyi, C., Orfi, E., Rosivall, L., Nemes, R., Kok, R. J., Metselaar, J. M., Storm, G. & Szebeni, J., dec. 10 2014, In : Journal of Controlled Release. 195, p. 2-10 9 p.

Research output: Article

41 Citations (Scopus)

Hypersensitivity reactions to intravenous iron: Guidance for risk minimization and management

Rampton, D., Folkersen, J., Fishbane, S., Hedenus, M., Howaldt, S., Locatelli, F., Patni, S., Szebeni, J. & Weiss, G., nov. 1 2014, In : Haematologica. 99, 11, p. 1671-1676 6 p.

Research output: Article

119 Citations (Scopus)

Hypersensitivity reactions to intravenous lipid emulsion in Swine: Relevance for lipid resuscitation studies

Bedocs, P., Capacchione, J., Potts, L., Chugani, R., Weiszhar, Z., Szebeni, J. & Buckenmaier, C. C., nov. 4 2014, In : Anesthesia and analgesia. 119, 5, p. 1094-1101 8 p.

Research output: Article

19 Citations (Scopus)
2013

Complement activation by PEGylated liposomes containing prednisolone

Van Den Hoven, J. M., Nemes, R., Metselaar, J. M., Nuijen, B., Beijnen, J. H., Storm, G. & Szebeni, J., máj. 13 2013, In : European Journal of Pharmaceutical Sciences. 49, 2, p. 265-271 7 p.

Research output: Article

37 Citations (Scopus)