J. Szöllősi

  • Hungary

  • 6643 Citations
  • 44 h-Index
1968 …2019
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Research Output 1968 2019

2019
Open Access
Fluorescence Recovery After Photobleaching
Photobleaching
Fluorescence Spectrometry
Epidermal Growth Factor Receptor
Fluorescence

Homo- and Heteroassociations Drive Activation of ErbB3

Váradi, T., Schneider, M., Sevcsik, E., Kiesenhofer, D., Baumgart, F., Batta, G., Kovács, T., Platzer, R., Huppa, J. B., Szöllősi, J., Schütz, G. J., Brameshuber, M. & Nagy, P., jan. 1 2019, (Accepted/In press) In : Biophysical journal.

Research output: Article

Open Access
Neuregulin-1
Hominidae
Dimerization
Actin Cytoskeleton
Protein-Tyrosine Kinases
3 Citations (Scopus)

Molecular mechanisms and bioavailability of polyphenols in prostate cancer

Costea, T., Nagy, P., Ganea, C., Szöllősi, J. & Mocanu, M. M., márc. 1 2019, In : International journal of molecular sciences. 20, 5, 1062.

Research output: Review article

Open Access
bioavailability
Polyphenols
Biological Availability
Prostatic Neoplasms
cancer
1 Citation (Scopus)

Reducing the Detrimental Effects of Saturation Phenomena in FRET Microscopy

Szendi-Szatmári, T., Szabó, Á., Szöllősi, J. & Nagy, P., máj. 7 2019, In : Analytical Chemistry. 91, 9, p. 6378-6382 5 p.

Research output: Article

Open Access
Energy transfer
Microscopic examination
Proteins
Experiments
2018
8 Citations (Scopus)
Exosomes
Caspases
Growth
Neoplasms
Caspase 7
2 Citations (Scopus)

Flow cytometric FRET analysis of protein interactions

Ujlaky-Nagy, L., Nagy, P., Szöllősi, J. & Vereb, G., jan. 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 393-419 27 p. (Methods in Molecular Biology; vol. 1678).

Research output: Chapter

Fluorescence Resonance Energy Transfer
Proteins
Flow Cytometry
Biochemistry
Publications
16 Citations (Scopus)

The Effect of Fluorophore Conjugation on Antibody Affinity and the Photophysical Properties of Dyes

Szabó, Á., Szendi-Szatmári, T., Ujlaky-Nagy, L., Rádi, I., Vereb, G., Szöllősi, J. & Nagy, P., febr. 6 2018, In : Biophysical Journal. 114, 3, p. 688-700 13 p.

Research output: Article

Antibody Affinity
Coloring Agents
Antibodies
Fluorescence
Fluorescence Polarization
2017

Detection of protein interactions by Subcellular Localization Assay

Mocanu, M. M., Nagy, P. & Szöllősi, J., júl. 1 2017, In : Cytometry Part A. 91, 7, p. 657-658 2 p.

Research output: Comment/debate

Flow Cytometry
Proteins
2 Citations (Scopus)

Epigallocatechin-3-O-gallate alleviates the malignant phenotype in A-431 epidermoid and SK-BR-3 breast cancer cell lines

Filippi, A., Picot, T., Aanei, C. M., Nagy, P., Szöllősi, J., Campos, L., Ganea, C. & Mocanu, M. M., nov. 21 2017, (Accepted/In press) In : International Journal of Food Sciences and Nutrition. p. 1-14 14 p.

Research output: Article

epigallocatechin
breast neoplasms
cell lines
Phenotype
phenotype
3 Citations (Scopus)
Caspases
Electric Impedance
Antibody Formation
Permeability
Membranes
6 Citations (Scopus)
Cell membranes
Membrane Lipids
Cells
Cell Membrane
Membrane Microdomains
2016
1 Citation (Scopus)

Association between periodontal status and idiopathic male infertility

Pásztor, N., Kárpáti, K., Szöllősi, J., Keresztúri, M., Kozinszky, Z., Gorzó, I. & Radnai, M., jún. 1 2016, In : Journal of oral science. 58, 2, p. 247-253 7 p.

Research output: Article

Male Infertility
Spermatozoa
Asthenozoospermia
Periodontal Pocket
Semen Analysis
6 Citations (Scopus)
Platelet-Derived Growth Factor Receptors
Glioblastoma
Phosphorylation
Membrane Microdomains
Lipids
8 Citations (Scopus)
Energy Transfer
Protein Conformation
Masks
Photons
Calibration
9 Citations (Scopus)

The Dipole Potential Modifies the Clustering and Ligand Binding Affinity of ErbB Proteins and Their Signaling Efficiency

Kovács, T., Batta, G., Hajdu, T., Szabó, Á., Váradi, T., Zákány, F., Csomós, I., Szöllősi, J. & Nagy, P., okt. 24 2016, In : Scientific Reports. 6, 35850.

Research output: Article

Epidermal Growth Factor
Cluster Analysis
Ligands
Energy Transfer
Protein-Tyrosine Kinases
2015
33 Citations (Scopus)

Chemoprevention of breast cancer by dietary polyphenols

Mocanu, M. M., Nagy, P., Szöllősi, J., Vanden Eynde, J. J. & Mayence, A., dec. 17 2015, In : Molecules. 20, 12, p. 22578-22620 43 p.

Research output: Article

Chemoprevention
Polyphenols
breast
cancer
Breast Neoplasms
60 Citations (Scopus)

Understanding FRET as a research tool for cellular studies

Shrestha, D., Jenei, A., Nagy, P., Vereb, G. & Szöllősi, J., márc. 25 2015, In : International Journal of Molecular Sciences. 16, 4, p. 6718-6756 39 p.

Research output: Article

Energy Transfer
Energy transfer
energy transfer
Research
Microscopy
2014
1 Citation (Scopus)
Fluorescence Resonance Energy Transfer
Optical Imaging
Fluorescence Microscopy
Flow Cytometry
Fluorescence
3 Citations (Scopus)
G(M1) Ganglioside
Lymphocytes
Detergents
Fluorescence Resonance Energy Transfer
B-Lymphocytes
10 Citations (Scopus)

Epigallocatechin 3-O-gallate induces 67 kDa laminin receptor-mediated cell death accompanied by downregulation of ErbB proteins and altered lipid raft clustering in mammary and epidermoid carcinoma cells

Mocanu, M. M., Ganea, C., Georgescu, L., Váradi, T., Shrestha, D., Baran, I., Katona, E., Nagy, P. & Szöllősi, J., febr. 28 2014, In : Journal of Natural Products. 77, 2, p. 250-257 8 p.

Research output: Article

Laminin Receptors
Cell death
Cluster Analysis
Squamous Cell Carcinoma
Cell Death
1 Citation (Scopus)
Laser Scanning Cytometry
Fluorescence Resonance Energy Transfer
Cells
Scanning
Imaging techniques
10 Citations (Scopus)
Energy Transfer
Microscopy
Photons
Likelihood Functions
Protein Conformation
17 Citations (Scopus)

TCRs genetically linked to CD28 and CD3ε Do not mispair with endogenous tcr chains and mediate enhanced T cell persistence and anti-melanoma activity

Govers, C., Sebestyén, Z., Roszik, J., Van Brakel, M., Berrevoets, C., Szöor, Á., Panoutsopoulou, K., Broertjes, M., Van, T., Vereb, G., Szöllősi, J. & Debets, R., nov. 15 2014, In : Journal of Immunology. 193, 10, p. 5315-5326 12 p.

Research output: Article

Melanoma
T-Lymphocytes
Transgenes
Synapses
Adoptive Transfer
2013
1 Citation (Scopus)
Flow Cytometry
16 Citations (Scopus)

High throughput FRET analysis of protein-protein interactions by slide-based imaging laser scanning cytometry

Szalóki, N., Doan-Xuan, Q. M., Szöllősi, J., Tóth, K., Vámosi, G. & Bacsó, Z., 2013, In : Cytometry Part A. 83, 9, p. 818-829 12 p.

Research output: Article

Laser Scanning Cytometry
Fluorescence Resonance Energy Transfer
Proteins
Flow Cytometry
Image Cytometry
5 Citations (Scopus)

Hypoxia reduces the efficiency of elisidepsin by inhibiting hydroxylation and altering the structure of lipid rafts

Király, A., Váradi, T., Hajdu, T., Rühl, R., Galmarini, C. M., Szöllősi, J. & Nagy, P., dec. 2013, In : Marine Drugs. 11, 12, p. 4858-4875 18 p.

Research output: Article

Hydroxylation
Lipids
Membranes
Cell Membrane
elisidepsin
37 Citations (Scopus)

The hitchhikers guide to cancer stem cell theory: Markers, pathways and therapy

Fábián, Á., Vereb, G. & Szöllosi, J., jan. 2013, In : Cytometry Part A. 83 A, 1, p. 62-71 10 p.

Research output: Article

Neoplastic Stem Cells
Neoplasms
Stem Cells
Therapeutics
Population
10 Citations (Scopus)

TripleFRET measurements in flow cytometry

Fábián, Á., Horváth, G., Vámosi, G., Vereb, G. & Szöllősi, J., ápr. 2013, In : Cytometry Part A. 83 A, 4, p. 375-385 11 p.

Research output: Article

Fluorescence Resonance Energy Transfer
Flow Cytometry
Energy Transfer
Coloring Agents
Protein Conformation
1 Citation (Scopus)

TripleFRET measurements in flow cytometry

Fábián, Á., Horváth, G., Vámosi, G., Vereb, G. & Szöllősi, J., júl. 2013, In : Cytometry Part A. 83, 7, p. 672 1 p.

Research output: Article

Flow Cytometry
5 Citations (Scopus)

Validating pharmacological disruption of protein-protein interactions by acceptor photobleaching FRET imaging

Roszik, J., Tóth, G., Szöllősi, J. & Vereb, G., 2013, Methods in Molecular Biology. Humana Press Inc., Vol. 986. p. 165-178 14 p. (Methods in Molecular Biology; vol. 986).

Research output: Chapter

Photobleaching
Fluorescence Resonance Energy Transfer
Pharmacology
Proteins
Microscopy
2012
9 Citations (Scopus)

Bare lymphocyte syndrome: An opportunity to discover our immune system

Shrestha, D., Szöllősi, J. & Jenei, A., jan. 30 2012, In : Immunology Letters. 141, 2, p. 147-157 11 p.

Research output: Article

Severe Combined Immunodeficiency
Immune System
Major Histocompatibility Complex
Antigen Presentation
Narration
9 Citations (Scopus)

Binding of Trastuzumab to ErbB2 Is Inhibited by a High Pericellular Density of Hyaluronan

Váradi, T., Mersich, T., Auvinen, P., Tammi, R., Tammi, M., Salamon, F., Besznyák, I., Jakab, F., Baranyai, Z., Szöllősi, J. & Nagy, P., aug. 2012, In : Journal of Histochemistry and Cytochemistry. 60, 8, p. 567-575 9 p.

Research output: Article

Hyaluronic Acid
Hyaluronoglucosaminidase
Membranes
Antibodies
Trastuzumab

Clinical cytometry in Europe, 2012.

Kappelmayer, J., Rawstron, A., Szöllősi, J. & Gratama, J. W., nov. 2012, In : Cytometry Part B - Clinical Cytometry. 82, 6, p. 372-373 2 p.

Research output: Article

Immunophenotyping
Cell Separation
Lymphoma
Flow Cytometry
Leukemia
12 Citations (Scopus)

Comparative study of the three different fluorophore antibody conjugation strategies

Shrestha, D., Bagosi, A., Szöllősi, J. & Jenei, A., szept. 2012, In : Analytical and Bioanalytical Chemistry. 404, 5, p. 1449-1463 15 p.

Research output: Article

Fluorophores
Antibodies
Amines
Antigens
Labeling

How to avoid bleeding in Förster resonance energy transfer

Nagy, P. & Szöllősi, J., febr. 2012, In : Cytometry Part A. 81 A, 2, p. 108-109 2 p.

Research output: Article

Protein Interaction Mapping
Luminescent Proteins
Image Cytometry
Fluorescence Resonance Energy Transfer
Energy Transfer
2011
31 Citations (Scopus)

Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway

Blanáthoma, O. V., Jelínková, I., Szöor, Á., Skender, B., Souček, K., Horváth, V., Vaculová, A., Anděra, L., Sova, P., Szöllősi, J., Hofmanová, J., Vereb, G. & Kozubík, A., 2011, In : Carcinogenesis. 32, 1, p. 42-51 10 p.

Research output: Article

Platinum
Cisplatin
Apoptosis
Colonic Neoplasms
TNF-Related Apoptosis-Inducing Ligand Receptors
21 Citations (Scopus)

Comparative analysis of fluorescence resonance energy transfer (FRET) and proximity ligation assay (PLA)

Mocanu, M. M., Váradi, T., Szöllősi, J. & Nagy, P., máj. 2011, In : Proteomics. 11, 10, p. 2063-2070 8 p.

Research output: Article

Fluorescence Resonance Energy Transfer
Ligation
Assays
Fluorophores
Antibodies
13 Citations (Scopus)

ErbB protein modifications are secondary to severe cell membrane alterations induced by elisidepsin treatment

Váradi, T., Roszik, J., Lisboa, D., Vereb, G., Molina-Guijarro, J. M., Galmarini, C. M., Szöllősi, J. & Nagy, P., szept. 30 2011, In : European Journal of Pharmacology. 667, 1-3, p. 91-99 9 p.

Research output: Article

Cell Membrane
Proteins
elisidepsin
Fluorescence Polarization
Membranes
12 Citations (Scopus)
Fluorescence Resonance Energy Transfer
Proteins
Biochemistry
Publications
Flow Cytometry
2 Citations (Scopus)
Cultured Tumor Cells
Circulating Neoplastic Cells
Microfluidic Analytical Techniques
Neoplasm Metastasis
Research
13 Citations (Scopus)

T-cell synapse formation depends on antigen recognition but not CD3 interaction: Studies with TCR:ζ, a candidate transgene for TCR gene therapy

Roszik, J., Sebestyén, Z., Govers, C., Guri, Y., Szöor, Á., Pályi-Krekk, Z., Vereb, G., Nagy, P., Szöllősi, J. & Debets, R., máj. 2011, In : European Journal of Immunology. 41, 5, p. 1288-1297 10 p.

Research output: Article

T-Cell Receptor Genes
T-Cell Antigen Receptor
Transgenes
Genetic Therapy
Synapses
16 Citations (Scopus)
Hyaluronic Acid
Fertilization
Infertility
Intracytoplasmic Sperm Injections
Embryonic Development
1 Citation (Scopus)
Insemination
Endometriosis
Gonadotropin-Releasing Hormone
Laparoscopy
Pregnancy Rate
2010
2 Citations (Scopus)

Characterization of a novel, trastuzumab resistant human breast cancer cell line

Barok, M., Balázs, M., Lazar, V., Rákosy, Z., Toth, E., Treszl, A., Vereb, G., Colbern, G. T., Park, J. W. & Szöllősi, J., jan. 1 2010, In : Frontiers in bioscience (Elite edition). 2 E, 2, p. 627-640 14 p.

Research output: Article

Heterografts
Cells
Breast Neoplasms
Cell Line
Gene expression
9 Citations (Scopus)

Coclustering of ErbB1 and ErbB2 revealed by FRET-sensitized acceptor bleaching

Szabó, Á., Szöllősi, J. & Nagy, P., júl. 7 2010, In : Biophysical Journal. 99, 1, p. 105-114 10 p.

Research output: Article

Fluorescence Resonance Energy Transfer
Ligands
Protein Multimerization
Epidermal Growth Factor
Research Personnel

CYTO 2010-overview of the XXV ISAC congress proceedings issue of cytometry part A

Szöllősi, J. & Smith, P. J., máj. 2010, In : Cytometry Part A. 77, 5, p. 407-409 3 p.

Research output: Article

Fluorescent Dyes
Protein Binding
Organelles
Histones
Nanoparticles
11 Citations (Scopus)
Cell Membrane
Membrane Microdomains
Lipids
Weapons
Eukaryotic Cells
29 Citations (Scopus)

Strength in Numbers: Effects of Acceptor Abundance on FRET Efficiency

Fábián, Á. I., Rente, T., Szöllősi, J., Mátyus, L. & Jenei, A., dec. 2010, In : ChemPhysChem. 11, 17, p. 3713-3721 9 p.

Research output: Article

resonance fluorescence
energy transfer
Fluorophores
Biological systems
antibodies
2009
Immunotherapy
Antibodies
corrigendum