• 7212 Citations
  • 42 h-Index
1967 …2020

Research output per year

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Research Output

2020

Novel Na+/Ca2+ exchanger inhibitor ORM-10962 supports coupled function of funny-current and Na+/ Ca2+ exchanger in pacemaking of rabbit sinus node tissue

Kohajda, Z., Tóth, N., Szlovák, J., Loewe, A., Bitay, G., Gazdag, P., Prorok, J., Jost, N., Levijoki, J., Pollesello, P., Papp, J. G., Varró, A. & Nagy, N., jan. 1 2020, In : Frontiers in Pharmacology. 10, 1632.

Research output: Article

Open Access
2019
2018

Complex electrophysiological remodeling in postinfarction ischemic heart failure

Hegyi, B., Bossuyt, J., Griffiths, L. G., Shimkunas, R., Coulibaly, Z., Jian, Z., Grimsrud, K. N., Sondergaard, C. S., Ginsburg, K. S., Chiamvimonvat, N., Belardinelli, L., Varró, A., Papp, J., Pollesello, P., Levijoki, J., Izu, L. T., Boyd, W. D., Bányász, T., Bers, D. M. & Chen-Izu, Y., márc. 27 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 13, p. E3036-E3044

Research output: Article

17 Citations (Scopus)

Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes

Oravecz, K., Kormos, A., Gruber, A., Márton, Z., Kohajda, Z., Mirzaei, L., Jost, N., Levijoki, J., Pollesello, P., Koskelainen, T., Otsomaa, L., Tóth, A., Papp, J. G., Nánási, P. P., Antoons, G., Varró, A., Acsai, K. & Nagy, N., jan. 5 2018, In : European Journal of Pharmacology. 818, p. 278-286 9 p.

Research output: Article

1 Citation (Scopus)

Long-term endurance training-induced cardiac adaptation in new rabbit and dog animal models of the human athlete's heart

Polyák, A., Kui, P., Morvay, N., Leprán, I., Ágoston, G., Varga, A., Nagy, N., Baczkó, I., Farkas, A., Papp, J. G., Varró, A. & Farkas, A. S., jan. 1 2018, In : Reviews in cardiovascular medicine. 19, 4, p. 135-142 8 p.

Research output: Article

Open Access
2 Citations (Scopus)
2017

Increased short-term beat-to-beat QT interval variability in patients with impaired glucose tolerance

Orosz, A., Baczkó, I., Nyiraty, S., Körei, A. E., Putz, Z., Takács, R., Nemes, A., Várkonyi, T., Balogh, L., Ábrahám, G., Kempler, P., Papp, J., Varró, A. & Lengyel, C., jún. 13 2017, In : Frontiers in Endocrinology. 8, JUN, 129.

Research output: Article

7 Citations (Scopus)
2016

Calcium sensitizers: What have we learned over the last 25 years?

Pollesello, P., Papp, Z. & Papp, J., jan. 15 2016, In : International Journal of Cardiology. 203, p. 543-548 6 p.

Research output: Article

33 Citations (Scopus)

Hyperventilation assists proarrhythmia development during delayed repolarization in clofilium-treated, anaesthetized, mechanically ventilated rabbits

Papp, H., Sarusi, A., Farkas, A. S., Takacs, H., Kui, P., Vincze, D., Ivany, E., Varró, A., Papp, J., Forster, T. & Farkas, A., okt. 1 2016, In : Journal of Physiology and Pharmacology. 67, 5, p. 731-737 7 p.

Research output: Article

1 Citation (Scopus)

New in vitro model for proarrhythmia safety screening: IKs inhibition potentiates the QTc prolonging effect of IKr inhibitors in isolated guinea pig hearts

Kui, P., Orosz, S., Takács, H., Sarusi, A., Csík, N., Rárosi, F., Cseko, C., Varró, A., Papp, J., Forster, T., Farkas, A. S. & Farkas, A., júl. 1 2016, In : Journal of Pharmacological and Toxicological Methods. 80, p. 26-34 9 p.

Research output: Article

6 Citations (Scopus)

ORM-3819 promotes cardiac contractility through Ca2+ sensitization in combination with selective PDE III inhibition, a novel approach to inotropy

Nagy, L., Pollesello, P., Haikala, H., Végh, A., Sorsa, T., Levijoki, J., Szilágyi, S., Édes, I., Tóth, A., Papp, Z. & Papp, J., márc. 15 2016, In : European Journal of Pharmacology. 775, p. 120-129 10 p.

Research output: Article

1 Citation (Scopus)
1 Citation (Scopus)
2015
14 Citations (Scopus)

Identification and functional characterisation of a novel KCNJ2 mutation, Val302del, causing andersen–tawil syndrome

Ördög, B., Hategan, L., Kovács, M., Seprényi, G., Kohajda, Z., Nagy, I., Hegedűs, Z., Környei, L., Jost, N., Katona, M., Szekeres, M., Forster, T., Papp, J. G., Varró, A. & Sepp, R., márc. 11 2015, In : Canadian journal of physiology and pharmacology. 93, 7, p. 569-575 7 p.

Research output: Article

2 Citations (Scopus)

Increased short-term beat-to-beat variability of QT interval in patients with acromegaly

Orosz, A., Csajbók, É., Czékus, C., Gavallér, H., Magony, S., Valkusz, Z., Várkonyi, T. T., Nemes, A., Baczkó, I., Forster, T., Wittmann, T., Papp, J. G., Varró, A. & Lengyel, C., ápr. 27 2015, In : PloS one. 10, 4, e0125639.

Research output: Article

5 Citations (Scopus)
2 Citations (Scopus)
2 Citations (Scopus)
4 Citations (Scopus)
2014

Absolute beat-to-beat variability and instability parameters of ECG intervals: Biomarkers for predicting ischaemia-induced ventricular fibrillation

Sarusi, A., Rárosi, F., Szúcs, M., Csík, N., Farkas, A. S., Papp, J. G., Varrõ, A., Forster, T., Curtis, M. J. & Farkas, A., jan. 1 2014, In : British journal of pharmacology. 171, 7, p. 1772-1782 11 p.

Research output: Article

12 Citations (Scopus)

Assessment of efficacy of proarrhythmia biomarkers in isolated rabbit hearts with attenuated repolarization reserve

Orosz, S., Sarusi, A., Csík, N., Papp, J. G., Varró, A., Farkas, S., Forster, T., Farkas, A. S. & Farkas, A., szept. 1 2014, In : Journal of cardiovascular pharmacology. 64, 3, p. 266-276 11 p.

Research output: Article

3 Citations (Scopus)

Efficacy of selective NCX inhibition by ORM-10103 during simulated ischemia/reperfusion

Kormos, A., Nagy, N., Acsai, K., Váczi, K., Ágoston, S., Pollesello, P., Levijoki, J., Szentandrássy, N., Papp, J. G., Varró, A. & Tóth, A., okt. 5 2014, In : European Journal of Pharmacology. 740, p. 539-551 13 p.

Research output: Article

9 Citations (Scopus)
2 Citations (Scopus)

Selective Na +/ Ca 2+ exchanger inhibition prevents Ca 2+ overload-induced triggered arrhythmias

Nagy, N., Kormos, A., Kohajda, Z., Szebeni, Á., Szepesi, J., Pollesello, P., Levijoki, J., Acsai, K., Virág, L., Nánási, P. P., Papp, J. G., Varrõ, A. & Tõth, A., dec. 2014, In : British journal of pharmacology. 171, 24, p. 5665-5681 17 p.

Research output: Article

25 Citations (Scopus)
2013

Altered expression of genes for kir ion channels in dilated cardiomyopathy

Szuts, V., Ménesi, D., Varga-Orvos, Z., Zvara, Á., Houshmand, N., Bitay, M., Bogáts, G., Virág, L., Baczkó, I., Szalontai, B., Geramipoor, A., Cotella, D., Wettwer, E., Ravens, U., Deák, F., Puskás, L. G., Papp, J. G., Kiss, I., Varró, A. & Jost, N., aug. 1 2013, In : Canadian journal of physiology and pharmacology. 91, 8, p. 648-656 9 p.

Research output: Article

14 Citations (Scopus)
17 Citations (Scopus)
14 Citations (Scopus)

Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs

Jost, N., Virág, L., Comtois, P., Ördög, B., Szuts, V., Seprényi, G., Bitay, M., Kohajda, Z., Koncz, I., Nagy, N., Szél, T., Magyar, J., Kovács, M., Puskás, L. G., Lengyel, C., Wettwer, E., Ravens, U., Nánási, P. P., Papp, J. G., Varró, A. & 1 others, Nattel, S., szept. 1 2013, In : Journal of Physiology. 591, 17, p. 4189-4206 18 p.

Research output: Article

70 Citations (Scopus)

ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart

Jost, N., Nagy, N., Corici, C., Kohajda, Z., Horváth, A., Acsai, K., Biliczki, P., Levijoki, J., Pollesello, P., Koskelainen, T., Otsomaa, L., Tõth, A., Papp, J. G., Varrõ, A. & Virág, L., okt. 1 2013, In : British journal of pharmacology. 170, 4, p. 768-778 11 p.

Research output: Review article

34 Citations (Scopus)
2012

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve

Kristóf, A., Husti, Z., Koncz, I., Kohajda, Z., Szél, T., Juhász, V., Biliczki, P., Jost, N., Baczkó, I., Papp, J. G., Varró, A. & Virág, L., dec. 31 2012, In : PloS one. 7, 12, e53255.

Research output: Article

8 Citations (Scopus)
11 Citations (Scopus)

What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart

Szûts, V., Ötvös, F., Dézsi, L., Vágvölgyi, C., Szalontai, B., Dobrzynski, H., Boyett, M., Zhang, H., Papp, J. G., Varró, A., Benyhe, S. & Erdélyi, L., dec. 1 2012, In : Acta Biologica Szegediensis. 56, 2, p. 93-107 15 p.

Research output: Review article

4 Citations (Scopus)
2011

Analysis of the contribution of I to to repolarization in canine ventricular myocardium

Virág, L., Jost, N., Papp, R., Koncz, I., Kristóf, A., Kohajda, Z., Harmati, G., Carbonell-Pascual, B., Ferrero, J. M., Papp, J. G., Nánási, P. P. & Varró, A., szept. 1 2011, In : British journal of pharmacology. 164, 1, p. 93-105 13 p.

Research output: Article

15 Citations (Scopus)

Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations

Szél, T., Koncz, I., Jost, N., Baczkó, I., Husti, Z., Virág, L., Bussek, A., Wettwer, E., Ravens, U., Papp, J. G. & Varró, A., júl. 15 2011, In : European Journal of Pharmacology. 662, 1-3, p. 31-39 9 p.

Research output: Article

25 Citations (Scopus)

Electrophysiological effects of ivabradine in dog and human cardiac preparations: Potential antiarrhythmic actions

Koncz, I., Szél, T., Bitay, M., Cerbai, E., Jaeger, K., Fülöp, F., Jost, N., Virág, L., Orvos, P., Tálosi, L., Kristóf, A., Baczkó, I., Papp, J. G. & Varró, A., okt. 15 2011, In : European Journal of Pharmacology. 668, 3, p. 419-426 8 p.

Research output: Article

30 Citations (Scopus)

Increased short-term variability of the qt interval in professional soccer players: Possible implications for arrhythmia prediction

Lengyel, C., Orosz, A., Hegyi, P., Komka, Z., Udvardy, A., Bosnyák, E., Trájer, E., Pavlik, G., Tóth, M., Wittmann, T., Papp, J. G., Varró, A. & Baczkó, I., ápr. 25 2011, In : PloS one. 6, 4, e18751.

Research output: Article

16 Citations (Scopus)

Selective pharmacological inhibition of the pacemaker channel isoforms (HCN1-4) as new possible therapeutical targets

Koncz, I., Szél, T., Jaeger, K., Baczkó, I., Cerbai, E., Romanelli, M. N., Papp, J. G. & Varró, A., aug. 1 2011, In : Current medicinal chemistry. 18, 24, p. 3662-3674 13 p.

Research output: Article

18 Citations (Scopus)
2010
12 Citations (Scopus)
2009

5,7,8-trimethyl-benzopyran and 5,7,8-trimethyl-1,4-benzoxazine aminoamide derivatives as novel antiarrhythmics against ischemia-reperfusion injury

Koini, E. N., Papazafiri, P., Vassilopoulos, A., Koufaki, M., Horváth, Z., Koncz, I., Virág, L., Papp, G. J., Varró, A. & Calogeropoulou, T., ápr. 23 2009, In : Journal of Medicinal Chemistry. 52, 8, p. 2328-2340 13 p.

Research output: Article

38 Citations (Scopus)

Biseko® colloidal solution diminishes the vasoreactivity of human isolated radial arteries

Szolnoky, J., Ambrus, N., Szabó-Biczók, A., Bogáts, G., Papp, J. G., Varró, A. & Pataricza, J., júl. 1 2009, In : European Journal of Cardio-Thoracic Surgery. 36, 1, p. 143-147 5 p.

Research output: Article

2 Citations (Scopus)

Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?

Nagy, N., Szuts, V., Horváth, Z., Seprényi, G., Farkas, A. S., Acsai, K., Prorok, J., Bitay, M., Kun, A., Pataricza, J., Papp, J. G., Nánási, P. P., Varró, A. & Tóth, A., nov. 1 2009, In : Journal of Molecular and Cellular Cardiology. 47, 5, p. 656-663 8 p.

Research output: Article

61 Citations (Scopus)

Herpesvirus-mediated delivery of a genetically encoded fluorescent ca 2+ sensor to canine cardiomyocytes

Prorok, J., Kovács, P. P., Kristf, A. A., Nagy, N., Tombácz, D., Tth, J. S., Ördg, B., Jost, N., Virág, L., Papp, J. G., Varr, A., Tth, A. & Boldogki, Z., aug. 24 2009, In : Journal of Biomedicine and Biotechnology. 2009, 361795.

Research output: Article

12 Citations (Scopus)
21 Citations (Scopus)
20 Citations (Scopus)
2008

C-Type natriuretic peptide hyperpolarizes and relaxes human penile resistance arteries

Kun, A., Kiraly, I., Pataricza, J., Marton, Z., Krassoi, I., Varro, A., Simonsen, U., Papp, J. G. & Pajor, L., máj. 1 2008, In : Journal of Sexual Medicine. 5, 5, p. 1114-1125 12 p.

Research output: Article

34 Citations (Scopus)
22 Citations (Scopus)
4 Citations (Scopus)
26 Citations (Scopus)