• 777 Citations
  • 14 h-Index
20042019

Research output per year

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Research Output

  • 777 Citations
  • 14 h-Index
  • 26 Article
  • 2 Review article
  • 1 Comment/debate
  • 1 Letter
2019

Discovery and development of extreme selective inhibitors of the ITD and D835Y mutant FLT3 kinases

Baska, F., Sipos, A., Őrfi, Z., Nemes, Z., Dobos, J., Szántai-Kis, C., Szabó, E., Szénási, G., Dézsi, L., Hamar, P., Cserepes, M. T., Tóvári, J., Garamvölgyi, R., Krekó, M. & Őrfi, L., dec. 15 2019, In : European Journal of Medicinal Chemistry. 184, 111710.

Research output: Article

1 Citation (Scopus)

Targeted drug combination therapy design based on driver genes

Zsákai, L., Sipos, A., Dobos, J., Eros, D., Szántai-Kis, C., Bánhegyi, P., Pató, J., Orfi, L., Matula, Z., Mikala, G., Kéri, G., Peták, I. & Vályi-Nagy, I., jan. 1 2019, In : Oncotarget. 10, 51, p. 5255-5266 12 p.

Research output: Article

2018
3 Citations (Scopus)

Novel compounds with potent CDK9 inhibitory activity for the treatment of myeloma

Czudor, Z., Balogh, M., Bánhegyi, P., Boros, S., Breza, N., Dobos, J., Fábián, M., Horváth, Z., Illyés, E., Markó, P., Sipos, A., Szántai-Kis, C., Szokol, B. & Őrfi, L., febr. 15 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 769-773 5 p.

Research output: Article

3 Citations (Scopus)

Synthesis and characterization of amino acid substituted sunitinib analogues for the treatment of AML

Nemes, Z., Takács-Novák, K., Völgyi, G., Valko, K., Béni, S., Horváth, Z., Szokol, B., Breza, N., Dobos, J., Szántai-Kis, C., Illyés, E., Boros, S., Kok, R. J. & Őrfi, L., aug. 1 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 14, p. 2391-2398 8 p.

Research output: Article

2 Citations (Scopus)
2017
2 Citations (Scopus)
2016

Design and synthesis of new imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrazine derivatives with antiproliferative activity against melanoma cells

Garamvölgyi, R., Dobos, J., Sipos, A., Boros, S., Illyés, E., Baska, F., Kékesi, L., Szabadkai, I., Szántai-Kis, C., Kéri, G. & Őrfi, L., jan. 27 2016, In : European Journal of Medicinal Chemistry. 108, p. 623-643 21 p.

Research output: Article

14 Citations (Scopus)

KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models

Kenessey, I., Kói, K., Horváth, O., Cserepes, M., Molnár, D., Izsák, V., Dobos, J., Hegedus, B., Tóvári, J. & Tímár, J., 2016, In : Oncotarget. 7, 48, p. 79503-79514 12 p.

Research output: Article

5 Citations (Scopus)
2015
6 Citations (Scopus)

Prenylation inhibition-induced cell death in melanoma: Reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells

Garay, T., Kenessey, I., Molnár, E., Juhász, É., Réti, A., László, V., Rózsás, A., Dobos, J., Döme, B., Berger, W., Klepetko, W., Tóvári, J., Tímár, J. & Hegedus, B., febr. 3 2015, In : PloS one. 10, 2, e0117021.

Research output: Article

13 Citations (Scopus)

Sensitivity of Melanoma Cells to EGFR and FGFR Activation but Not Inhibition is Influenced by Oncogenic BRAF and NRAS Mutations

Garay, T., Molnár, E., Juhász, É., László, V., Barbai, T., Dobos, J., Schelch, K., Pirker, C., Grusch, M., Berger, W., Tímár, J. & Hegedűs, B., szept. 28 2015, In : Pathology and Oncology Research. 21, 4, p. 957-968 12 p.

Research output: Article

6 Citations (Scopus)
2013
27 Citations (Scopus)
2 Citations (Scopus)
2012
22 Citations (Scopus)
2011
16 Citations (Scopus)

Molecular characterization of 103 ovarian serous and mucinous tumors

Vereczkey, I., Serester, O., Dobos, J., Gallai, M., Szakács, O., Szentirmay, Z. & Tóth, E., szept. 1 2011, In : Pathology and Oncology Research. 17, 3, p. 551-559 9 p.

Research output: Article

40 Citations (Scopus)

Prognostic impact of B-cell density in cutaneous melanoma

Ladányi, A., Kiss, J., Mohos, A., Somlai, B., Liszkay, G., Gilde, K., Fejős, Z., Gaudi, I., Dobos, J. & Tímár, J., dec. 2011, In : Cancer Immunology, Immunotherapy. 60, 12, p. 1729-1738 10 p.

Research output: Article

89 Citations (Scopus)
2010

Apelin expression in human non-small cell lung cancer: Role in angiogenesis and prognosis

Berta, J., Kenessey, I., Dobos, J., Tovari, J., Klepetko, W., Jan Ankersmit, H., Hegedus, B., Renyi-Vamos, F., Varga, J., Lorincz, Z., Paku, S., Ostoros, G., Rozsas, A., Timar, J. & Dome, B., aug. 2010, In : Journal of Thoracic Oncology. 5, 8, p. 1120-1129 10 p.

Research output: Article

62 Citations (Scopus)

Inhibition of c-met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma

Kenessey, I., Keszthelyi, M., Krámer, Z., Berta, J., Ádám, A., Dobos, J., Mildner, M., Flachner, B., Cseh, S., Barna, G., Szokol, B., Orfi, L., Kéri, G., Döme, B., Klepetko, W., Tímár, J. & Tóvári, J., jún. 3 2010, In : Current cancer drug targets. 10, 3, p. 332-342 11 p.

Research output: Article

25 Citations (Scopus)
2009

A melanóma progresszióját befolyásoló endokrin tényezok

Judit, D., márc. 1 2009, In : Magyar onkologia. 53, 1, p. 47-50 4 p.

Research output: Review article

2 Citations (Scopus)
79 Citations (Scopus)

High VEGFR-3-positive circulating lymphatic/vascular endothelial progenitor cell level is associated with poor prognosis in human small cell lung cancer

Bogos, K., Renyi-Vamos, F., Dobos, J., Kenessey, I., Tovari, J., Timar, J., Strausz, J., Ostoros, G., Klepetko, W., Ankersmit, H. J., Lang, G., Hoda, M. A., Nierlich, P. & Dome, B., márc. 1 2009, In : Clinical Cancer Research. 15, 5, p. 1741-1746 6 p.

Research output: Article

43 Citations (Scopus)

In response

Bogos, K., Renyi-Vamos, F., Dobos, J., Tovari, J., Ostoros, G. & Dome, B., nov. 1 2009, In : Clinical Cancer Research. 15, 21, p. 6740-6741 2 p.

Research output: Letter

2008
61 Citations (Scopus)
22 Citations (Scopus)
2007
4 Citations (Scopus)
165 Citations (Scopus)
2005
18 Citations (Scopus)
2004

In vitro and in vivo antitumor effect of 2-methoxyestradiol on human melanoma

Dobos, J., Tímár, J., Bocsi, J., Burián, Z., Nagy, K., Barna, G., Peták, I. & Ladányi, A., dec. 10 2004, In : International Journal of Cancer. 112, 5, p. 771-776 6 p.

Research output: Article

45 Citations (Scopus)