• 3006 Citations
  • 30 h-Index
1989 …2018

Research output per year

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Research Output

2018

The NAv1.7 blocker protoxin II reduces burn injury-induced spinal nociceptive processing

Torres-Pérez, J. V., Adamek, P., Palecek, J., Vizcaychipi, M., Nagy, I. & Varga, A., jan. 1 2018, In : Journal of Molecular Medicine. 96, 1, p. 75-84 10 p.

Research output: Article

3 Citations (Scopus)
2017

Inflammation of peripheral tissues and injury to peripheral nerves induce differing effects in the expression of the calcium-sensitive N-arachydonoylethanolamine-synthesizing enzyme and related molecules in rat primary sensory neurons

Sousa-Valente, J., Varga, A., Torres-Perez, J. V., Jenes, A., Wahba, J., Mackie, K., Cravatt, B., Ueda, N., Tsuboi, K., Santha, P., Jancso, G., Tailor, H., Avelino, A. & Nagy, I., jún. 1 2017, In : Journal of Comparative Neurology. 525, 8, p. 1778-1796 19 p.

Research output: Article

4 Citations (Scopus)

Phosphorylated Histone 3 at Serine 10 Identifies Activated Spinal Neurons and Contributes to the Development of Tissue Injury-Associated Pain

Torres-Pérez, J. V., Sántha, P., Varga, A., Szucs, P., Sousa-Valente, J., Gaal, B., Sivadó, M., Andreou, A. P., Beattie, S., Nagy, B., Matesz, K., Arthur, J. S. C., Jancsó, G. & Nagy, I., jan. 25 2017, In : Scientific reports. 7, 41221.

Research output: Article

3 Citations (Scopus)

Reply to thorneloe et al.

White, J. P. M., Cibelli, M., Urban, L., Nilius, B., McGeown, G. & Nagy, I., okt. 2017, In : Physiological reviews. 97, 4, p. 1233-1234 2 p.

Research output: Letter

2016

Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk

Chen, J., Varga, A., Selvarajah, S., Jenes, A., Dienes, B., Sousa-Valente, J., Kulik, A., Veress, G., Brain, S. D., Baker, D., Urban, L., Mackie, K. & Nagy, I., szept. 22 2016, In : Scientific Reports. 6, 33307.

Research output: Article

9 Citations (Scopus)

TRPV4: Molecular conductor of a diverse orchestra

White, J. P. M., Cibelli, M., Urban, L., Nilius, B., McGeown, J. G. & Nagy, I., júl. 2016, In : Physiological reviews. 96, 3, p. 911-973 63 p.

Research output: Article

98 Citations (Scopus)
2014

Anandamide in primary sensory neurons: Too much of a good thing?

Sousa-Valente, J., Varga, A., Ananthan, K., Khajuria, A. & Nagy, I., febr. 1 2014, In : European Journal of Neuroscience. 39, 3, p. 409-418 10 p.

Research output: Article

13 Citations (Scopus)

Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons

Varga, A., Jenes, A., Marczylo, T. H., Sousa-Valente, J., Chen, J., Austin, J., Selvarajah, S., Piscitelli, F., Andreou, A. P., Taylor, A. H., Kyle, F., Yaqoob, M., Brain, S., White, J. P. M., Csernoch, L., Di Marzo, V., Buluwela, L. & Nagy, I., júl. 2014, In : Pflugers Archiv European Journal of Physiology. 466, 7, p. 1421-1435 15 p.

Research output: Article

8 Citations (Scopus)

Pharmacology of the capsaicin receptor, transient receptor potential vanilloid type-1 ion channel

Nagy, I., Friston, D., Valente, J. S., Perez, J. V. T. & Andreou, A. P., jan. 1 2014, Capsaicin as a Therapeutic Molecule. Birkhauser Verlag AG, p. 39-76 38 p. (Progress in Drug Research; vol. 68).

Research output: Chapter

33 Citations (Scopus)

Prolonged exposure to bradykinin and prostaglandin E2 increases TRPV1 mRNA but does not alter TRPV1 and TRPV1b protein expression in cultured rat primary sensory neurons

Mistry, S., Paule, C. C., Varga, A., Photiou, A., Jenes, A., Avelino, A., Buluwela, L. & Nagy, I., ápr. 3 2014, In : Neuroscience Letters. 564, p. 89-93 5 p.

Research output: Article

8 Citations (Scopus)

Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics

Sousa-Valente, J., Andreou, A. P., Urban, L. & Nagy, I., máj. 2014, In : British journal of pharmacology. 171, 10, p. 2508-2527 20 p.

Research output: Review article

49 Citations (Scopus)
2013

Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons

Veress, G., Meszar, Z., Muszil, D., Avelino, A., Matesz, K., Mackie, K. & Nagy, I., máj. 1 2013, In : Brain Structure and Function. 218, 3, p. 733-750 18 p.

Research output: Article

30 Citations (Scopus)

Pain in intensive care: A personalized healthcare approach

Laycock, H., Ward, S., Halmshaw, C., Nagy, I. & Bantel, C., okt. 1 2013, In : Journal of the Intensive Care Society. 14, 4, p. 312-318 7 p.

Research output: Review article

4 Citations (Scopus)

Peripheral mechanisms of burn injury-associated pain

Laycock, H., Valente, J., Bantel, C. & Nagy, I., szept. 15 2013, In : European Journal of Pharmacology. 716, 1-3, p. 169-178 10 p.

Research output: Review article

12 Citations (Scopus)
1 Citation (Scopus)
2012

Isoflurane causes neocortical but not hippocampal-dependent memory impairment in mice

Fidalgo, A. R., Cibelli, M., White, J. P. M., Nagy, I., Wan, Y. & Ma, D., szept. 1 2012, In : Acta Anaesthesiologica Scandinavica. 56, 8, p. 1052-1057 6 p.

Research output: Article

11 Citations (Scopus)
2011

Extracellular signal-regulated kinases in pain of peripheral origin

White, J. P. M., Cibelli, M., Fidalgo, A. R. & Nagy, I., jan. 10 2011, In : European Journal of Pharmacology. 650, 1, p. 8-17 10 p.

Research output: Review article

12 Citations (Scopus)

Molecular structure of transient receptor potential vanilloid type 1 ion channel (TRPV1)

Urban, L., White, J. P. M. & Nagy, I., jan. 10 2011, In : Current Pharmaceutical Biotechnology. 12, 1, p. 115-121 7 p.

Research output: Article

6 Citations (Scopus)

Peripheral orthopaedic surgery down-regulates hippocampal brain-derived neurotrophic factor and impairs remote memory in mouse

Fidalgo, A. R., Cibelli, M., White, J. P. M., Nagy, I., Noormohamed, F., Benzonana, L., Maze, M. & Ma, D., szept. 5 2011, In : Neuroscience. 190, p. 194-199 6 p.

Research output: Article

23 Citations (Scopus)

Severe burn injury induces a characteristic activation of extracellular signal-regulated kinase 1/2 in spinal dorsal horn neurons

White, J. P. M., Ko, C. W., Fidalgo, A. R., Cibelli, M., Paule, C. C., Anderson, P. J., Cruz, C., Gomba, S., Matesz, K., Veress, G., Avelino, A. & Nagy, I., aug. 1 2011, In : European Journal of Pain. 15, 7, p. 683-690 8 p.

Research output: Article

4 Citations (Scopus)

Systemic inflammation enhances surgery-induced cognitive dysfunction in mice

Fidalgo, A. R., Cibelli, M., White, J. P. M., Nagy, I., Maze, M. & Ma, D., júl. 1 2011, In : Neuroscience Letters. 498, 1, p. 63-66 4 p.

Research output: Article

77 Citations (Scopus)

TRPV1 function in health and disease

White, J. P. M., Urban, L. & Nagy, I., jan. 10 2011, In : Current Pharmaceutical Biotechnology. 12, 1, p. 130-144 15 p.

Research output: Article

40 Citations (Scopus)

Xenon fails to inhibit capsaicin-evoked CGRP release by nociceptors in culture

Calcott, G., White, J. P. M. & Nagy, I., júl. 20 2011, In : Neuroscience Letters. 499, 2, p. 124-126 3 p.

Research output: Article

5 Citations (Scopus)

Xenon reduces activation of transient receptor potential vanilloid type 1 (TRPV1) in rat dorsal root ganglion cells and in human TRPV1-expressing HEK293 cells

White, J. P. M., Calcott, G., Jenes, A., Hossein, M., Paule, C. C., Santha, P., Davis, J. B., Ma, D., Rice, A. S. C. & Nagy, I., jan. 1 2011, In : Life Sciences. 88, 3-4, p. 141-149 9 p.

Research output: Article

3 Citations (Scopus)
2010

Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators

Soneji, N. D., Paule, C. C., Mlynarczyk, M. & Nagy, I., júl. 1 2010, In : Life Sciences. 87, 5-6, p. 162-168 7 p.

Research output: Article

9 Citations (Scopus)

Role of transient receptor potential and acid-sensing ion channels in peripheral inflammatory pain

White, J. P. M., Cibelli, M., Rei Fidalgo, A., Paule, C. C., Noormohamed, F., Urban, L., Maze, M. & Nagy, I., márc. 2010, In : Anesthesiology. 112, 3, p. 729-741 13 p.

Research output: Review article

24 Citations (Scopus)

Sensitization of the transient receptor potential vanilloid type 1 ion channel by isoflurane or sevoflurane does not result in extracellular signal-regulated kinase 1/2 activation in rat spinal dorsal horn neurons

White, J. P. M., Cibelli, M., Fidalgo, A. R., Paule, C. C., Anderson, P. J., Jenes, A., Rice, A. S. C. & Nagy, I., márc. 17 2010, In : Neuroscience. 166, 2, p. 633-638 6 p.

Research output: Article

1 Citation (Scopus)
17 Citations (Scopus)
2009
36 Citations (Scopus)

Capsaicin-sensitive primary sensory neurons in the mouse express N-Acyl phosphatidylethanolamine phospholipase D

Nagy, B., Fedonidis, C., Photiou, A., Wahba, J., Paule, C. C., Ma, D., Buluwela, L. & Nagy, I., jún. 30 2009, In : Neuroscience. 161, 2, p. 572-577 6 p.

Research output: Article

11 Citations (Scopus)

Functional Transient Receptor Potential Vanilloid 1 is Expressed in Human Urothelial Cells

Charrua, A., Reguenga, C., Cordeiro, J. M., Correiade-Sá, P., Paule, C., Nagy, I., Cruz, F. & Avelino, A., dec. 1 2009, In : Journal of Urology. 182, 6, p. 2944-2950 7 p.

Research output: Article

50 Citations (Scopus)

Localization of the endocannabinoid-degrading enzyme fatty acid amide hydrolase in rat dorsal root ganglion cells and its regulation After peripheral nerve injury

Lever, I. J., Robinson, M., Cibelli, M., Paule, C., Santha, P., Yee, L., Hunt, S. P., Cravatt, B. F., Elphick, M. R., Nagy, I. & Rice, A. S. C., márc. 25 2009, In : Journal of Neuroscience. 29, 12, p. 3766-3780 15 p.

Research output: Article

44 Citations (Scopus)

Molecular Mechanisms of TRPV1-Mediated Pain

Nagy, I., Paule, C. C. & White, J. P. M., dec. 1 2009, In : NeuroImmune Biology. 8, C, p. 75-99 25 p.

Research output: Review article

12 Citations (Scopus)
2008

An historical introduction to the endocannabinoid and endovanilloid systems

Nagy, I., White, J. P. M., Paule, C. C. & Köfalvi, A., jan. 1 2008, Cannabinoids and the Brain. Springer US, p. 3-13 11 p.

Research output: Chapter

1 Citation (Scopus)

Cystitis is associated with TRPVIb-downregulation in rat dorsal root ganglia

Charrua, A., Reguenga, C., Paule, C. C., Nagy, I., Cruz, F. & Avelino, A., okt. 8 2008, In : Neuroreport. 19, 15, p. 1469-1472 4 p.

Research output: Article

17 Citations (Scopus)

Functional molecular biology of the TRPV1 ion channel

Nagy, I., White, J. P. M., Paule, C. C., Maze, M. & Urban, L., jan. 1 2008, Cannabinoids and the Brain. Springer US, p. 101-130 30 p.

Research output: Chapter

12 Citations (Scopus)
2007

Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes

Gram, D. X., Ahrén, B., Nagy, I., Olsen, U. B., Brand, C. L., Sundler, F., Tabanera, R., Svendsen, O., Carr, R. D., Santha, P., Wierup, N. & Hansen, A. J., jan. 1 2007, In : European Journal of Neuroscience. 25, 1, p. 213-223 11 p.

Research output: Article

98 Citations (Scopus)
29 Citations (Scopus)

Taking the sting out of pain

Nagy, I., Paule, C., White, J. & Urban, L., júl. 1 2007, In : British journal of pharmacology. 151, 6, p. 721-722 2 p.

Research output: Review article

2 Citations (Scopus)
2006

Mechanisms underlying joint pain

Nagy, I., Lukacs, K. V. & Urban, L., dec. 1 2006, In : Drug Discovery Today: Disease Mechanisms. 3, 3, p. 357-363 7 p.

Research output: Review article

1 Citation (Scopus)
2005
75 Citations (Scopus)

The distribution of sensory fibers immunoreactive for the TRPV1 (capsaicin) receptor in the human prostate

Dinis, P., Charrua, A., Avelino, A., Nagy, I., Quintas, J., Ribau, U. & Cruz, F., júl. 1 2005, In : European Urology. 48, 1, p. 162-167 6 p.

Research output: Article

49 Citations (Scopus)
2004

Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis

Dinis, P., Charrua, A., Avelino, A., Yaqoob, M., Bevan, S., Nagy, I. & Cruz, F., dec. 15 2004, In : Journal of Neuroscience. 24, 50, p. 11253-11263 11 p.

Research output: Article

161 Citations (Scopus)

The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology

Nagy, I., Sántha, P., Jancsó, G. & Urbán, L., okt. 1 2004, In : European Journal of Pharmacology. 500, 1-3 SPEC. ISS., p. 351-369 19 p.

Research output: Review article

212 Citations (Scopus)
2003

Activation of capsaicin-sensitive primary sensory neurones induces anandamide production and release

Ahluwalia, J., Yaqoob, M., Urban, L., Bevan, S. & Nagy, I., febr. 1 2003, In : Journal of neurochemistry. 84, 3, p. 585-591 7 p.

Research output: Article

73 Citations (Scopus)
140 Citations (Scopus)

Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons

Sathianathan, V., Avelino, A., Charrua, A., Santha, P., Matesz, K., Cruz, F. & Nagy, I., nov. 1 2003, In : European Journal of Neuroscience. 18, 9, p. 2477-2486 10 p.

Research output: Article

44 Citations (Scopus)
2002

Cannabinoid 1 receptors are expressed by nerve growth factor- and glial cell-derived neurotrophic factor-responsive primary sensory neurones

Ahluwalia, J., Urban, L., Bevan, S., Capogna, M. & Nagy, I., ápr. 3 2002, In : Neuroscience. 110, 4, p. 747-753 7 p.

Research output: Article

59 Citations (Scopus)

Endocannabinoids and pain: Spinal and peripheral analgesia in inflammation and neuropathy

Rice, A. S. C., Farquhar-Smith, W. P. & Nagy, I., jan. 1 2002, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 66, 2-3, p. 243-256 14 p.

Research output: Article

164 Citations (Scopus)