• 1658 Citations
  • 24 h-Index
20062019

Research output per year

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Research Output

  • 1658 Citations
  • 24 h-Index
  • 49 Article
  • 4 Comment/debate
  • 4 Review article
2019

Advantages of prophylactic versus conventionally scheduled heart failure therapy in an experimental model of doxorubicin-induced cardiomyopathy

Lódi, M., Priksz, D., Fülöp, G. Á., Bódi, B., Gyöngyösi, A., Nagy, L., Kovács, Á., Kertész, A. B., Kocsis, J., Édes, I., Csanádi, Z., Czuriga, I., Kisvárday, Z., Juhász, B., Lekli, I., Bai, P., Tóth, A., Papp, Z. & Czuriga, D., júl. 19 2019, In : Journal of Translational Medicine. 17, 1, 229.

Research output: Article

Open Access
1 Citation (Scopus)

A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety

Szőke, K., Czompa, A., Lekli, I., Szabados-Fürjesi, P., Herczeg, M., Csávás, M., Borbás, A., Herczegh, P. & Tósaki, A., ápr. 1 2019, In : European Journal of Pharmaceutical Sciences. 131, p. 159-166 8 p.

Research output: Article

Open Access
2 Citations (Scopus)

Correction: Protective role of air potato (Dioscorea bulbifera) of yam family in myocardial ischemic reperfusion injury (Food and Function (2010) 1 (278-283) DOI: 10.1039/c0fo00048e)

Vasanthi, H. R., Mukherjee, S., Ray, D., Jayachandran, K. S. P., Lekli, I. & Das, D. K., febr. 1 2019, In : Food and Function. 10, 2, 1 p.

Research output: Comment/debate

Open Access

Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety

Szőke, K., Czompa, A., Lekli, I., Szabados-Fürjesi, P., Herczeg, M., Csávás, M., Borbás, A., Herczegh, P. & Tósaki, A., aug. 1 2019, In : Data in Brief. 25, 104146.

Research output: Article

Open Access
1 Citation (Scopus)
Open Access
2 Citations (Scopus)

Inhibited autophagy may contribute to heme toxicity in cardiomyoblast cells

Gyongyosi, A., Szoke, K., Fenyvesi, F., Fejes, Z., Debreceni, I. B., Nagy, B., Tosaki, A. & Lekli, I., ápr. 16 2019, In : Biochemical and biophysical research communications. 511, 4, p. 732-738 7 p.

Research output: Article

Open Access
1 Citation (Scopus)

The role of autophagy and death pathways in dose-dependent isoproterenol-induced cardiotoxicity

Gyongyosi, A., Zilinyi, R., Czegledi, A., Tosaki, A., Tosaki, A. & Lekli, I., jan. 1 2019, In : Current pharmaceutical design. 25, 19, p. 2192-2198 7 p.

Research output: Article

Open Access
2 Citations (Scopus)
2018

Aged (Black) versus raw garlic against ischemia/reperfusion-induced cardiac complications

Czompa, A., Szoke, K., Prokisch, J., Gyongyosi, A., Bak, I., Balla, G., Tósaki, A. & Lekli, I., ápr. 1 2018, In : International Journal of Molecular Sciences. 19, 4, 1017.

Research output: Article

5 Citations (Scopus)
1 Citation (Scopus)

The cardioprotective effect of metformin in doxorubicin-induced cardiotoxicity: The role of autophagy

Zilinyi, R., Czompa, A., Czegledi, A., Gajtko, A., Pituk, D., Lekli, I. & Tósaki, A., jan. 1 2018, In : Molecules. 23, 5, 1184.

Research output: Article

23 Citations (Scopus)

The effects of long-term, low- and high-dose beta-carotene treatment in zucker diabetic fatty rats: The role of HO-1

Csepanyi, E., Czompa, A., Szabados-Furjesi, P., Lekli, I., Balla, J., Balla, G., Tosaki, A. & Bak, I., ápr. 10 2018, In : International journal of molecular sciences. 19, 4, 1132.

Research output: Article

2 Citations (Scopus)
7 Citations (Scopus)
2017

Antioxidant properties and oxidative transformation of different chromone derivatives

Csepanyi, E., Szabados-Furjesi, P., Kiss-Szikszai, A., Frensemeier, L. M., Karst, U., Lekli, I., Haines, D. D., Tosaki, A. & Bak, I., ápr. 2017, In : Molecules. 22, 4, 588.

Research output: Article

14 Citations (Scopus)

Effects of momordica charantia (Bitter Melon) on Ischemic Diabetic Myocardium

Czompa, A., Gyongyosi, A., Szoke, K., Bak, I., Csepanyi, E., Haines, D. D., Tósaki, A., Lekli, I. & McPhee, D. J., márc. 1 2017, In : Molecules. 22, 3, 488.

Research output: Article

5 Citations (Scopus)
2015

Cardiovascular effects of low versus high-dose beta-carotene in a rat model

Csepanyi, E., Czompa, A., Haines, D., Lekli, I., Bakondi, E., Balla, G., Tosaki, A. & Bak, I., okt. 27 2015, In : Pharmacological Research. 100, p. 148-156 9 p.

Research output: Article

19 Citations (Scopus)

Orally delivered sour cherry seed extract (SCSE) affects cardiovascular and hematological parameters in humans

Csiki, Z., Papp-Bata, A., Czompa, A., Nagy, A., Bak, I., Lekli, I., Javor, A., Haines, D. D., Balla, G. & Tosaki, A., márc. 2015, In : Phytotherapy Research. 29, 3, p. 444-449 6 p.

Research output: Article

9 Citations (Scopus)
2014

Cardioprotection afforded by sour cherry seed Kernel: The role of heme oxygenase-1

Czompa, A., Gyongyosi, A., Czegledi, A., Csepanyi, E., Bak, I., Haines, D. D., Tosaki, A. & Lekli, I., nov. 1 2014, In : Journal of cardiovascular pharmacology. 64, 5, p. 412-419 8 p.

Research output: Article

22 Citations (Scopus)
2013

The cellular autophagy markers Beclin-1 and LC3B-II are increased during reperfusion in fibrillated mouse hearts

Meyer, G., Czompa, A., Reboul, C., Csepanyi, E., Czegledi, A., Bak, I., Balla, G., Balla, J., Tosaki, A. & Lekli, I., dec. 1 2013, In : Current pharmaceutical design. 19, 39, p. 6912-6918 7 p.

Research output: Article

33 Citations (Scopus)
2012

Caveolin induces cardioprotection through epigenetic regulation

Das, M., Das, S., Lekli, I. & Das, D. K., dec. 1 2012, In : Journal of Cellular and Molecular Medicine. 16, 4, p. 888-895 8 p.

Research output: Article

18 Citations (Scopus)
3 Citations (Scopus)
87 Citations (Scopus)

Tocotrienols confer resistance to ischemia in hypercholesterolemic hearts: Insight with genomics

Das, S., Mukherjee, S., Lekli, I., Gurusamy, N., Bardhan, J., Raychoudhury, U., Chakravarty, R., Banerji, S., Knowlton, A. A. & Das, D. K., jan. 1 2012, In : Molecular and Cellular Biochemistry. 360, 1-2, p. 35-45 11 p.

Research output: Article

13 Citations (Scopus)
2011

Histamine and H1-histamine receptors faster venous circulation

Galajda, Z., Balla, J., Szentmiklosi, A. J., Biro, T., Czifra, G., Dobrosi, N., Cseppento, A., Patonay, L., Roszer, T., Balla, G., Popescu, L. M., Lekli, I. & Tosaki, A., dec. 1 2011, In : Journal of Cellular and Molecular Medicine. 15, 12, p. 2614-2623 10 p.

Research output: Article

6 Citations (Scopus)

Postischemic cardiac recovery in heme oxygenase-1 transgenic ischemic/reperfused mouse myocardium

Juhasz, B., Varga, B., Czompa, A., Bak, I., Lekli, I., Gesztelyi, R., Zsuga, J., Kemeny-Beke, A., Antal, M., Szendrei, L. & Tosaki, A., szept. 1 2011, In : Journal of Cellular and Molecular Medicine. 15, 9, p. 1973-1982 10 p.

Research output: Article

26 Citations (Scopus)
28 Citations (Scopus)
2010

Cardioprotection by resveratrol: A novel mechanism via autophagy involving the mTORC2 pathway

Gurusamy, N., Lekli, I., Mukherjee, S., Ray, D., Ahsan, M. K., Gherghiceanu, M., Popescu, L. M. & Das, D. K., ápr. 1 2010, In : Cardiovascular research. 86, 1, p. 103-112 10 p.

Research output: Article

190 Citations (Scopus)

Comparison of the protective effects of steamed and cooked broccolis on ischaemia-reperfusion-induced cardiac injury

Mukherjee, S., Lekli, I., Ray, D., Gangopadhyay, H., Raychaudhuri, U. & Das, D. K., márc. 1 2010, In : British Journal of Nutrition. 103, 6, p. 815-823 9 p.

Research output: Article

24 Citations (Scopus)

Co-ordinated autophagy with resveratrol and γ-tocotrienol confers synergetic cardioprotection

Lekli, I., Ray, D., Mukherjee, S., Gurusamy, N., Ahsan, M. K., Juhasz, B., Bak, I., Tosaki, A., Gherghiceanu, M., Popescu, L. M. & Das, D. K., okt. 1 2010, In : Journal of Cellular and Molecular Medicine. 14, 10, p. 2506-2518 13 p.

Research output: Article

44 Citations (Scopus)

Downregulation of cardiac lineage protein-1 confers cardioprotection through the upregulation of redox effectors

Gurusamy, N., Lekli, I., Ahsan, M. K., Ray, D., Mukherjee, S., Mascareno, E., Siddiqui, M. A. Q. & Das, D. K., jan. 4 2010, In : FEBS letters. 584, 1, p. 187-193 7 p.

Research output: Article

2 Citations (Scopus)
38 Citations (Scopus)

Functional recovery of diabetic mouse hearts by glutaredoxin-1 gene therapy: Role of Akt-FoxO-signaling network

Lekli, I., Mukherjee, S., Ray, D., Gurusamy, N., Kim, Y. H., Tosaki, A., Engelman, R. M., Ho, Y. S. & Das, D. K., ápr. 1 2010, In : Gene Therapy. 17, 4, p. 478-485 8 p.

Research output: Article

20 Citations (Scopus)
31 Citations (Scopus)

Longevity nutrients resveratrol, wines and grapes

Lekli, I., Ray, D. & Das, D. K., márc. 1 2010, In : Genes and Nutrition. 5, 1, p. 55-60 6 p.

Research output: Review article

38 Citations (Scopus)

Protective role of air potato (Dioscorea bulbifera) of yam family in myocardial ischemic reperfusion injury

Vasanthi, H. R., Mukherjee, S., Ray, D., Pandian Jayachandran, K. S., Lekli, I. & Das, D. K., nov. 30 2010, In : Food and Function. 1, 3, p. 278-283 6 p.

Research output: Article

13 Citations (Scopus)
9 Citations (Scopus)

Red wine antioxidant resveratrol-modified cardiac stem cells regenerate infarcted myocardium

Gurusamy, N., Ray, D., Lekli, I. & Das, D. K., szept. 1 2010, In : Journal of Cellular and Molecular Medicine. 14, 9, p. 2235-2239 5 p.

Research output: Review article

48 Citations (Scopus)
2009

BAG-1 induces autophagy for cardiac cell survival

Gurusamy, N., Lekli, I., Gherghiceanu, M., Popescu, L. M. & Das, D. K., jan. 1 2009, In : Autophagy. 5, 1, p. 120-121 2 p.

Research output: Article

42 Citations (Scopus)

Cardioprotection by adaptation to ischaemia augments autophagy in association with BAG-1 protein

Gurusamy, N., Lekli, I., Gorbunov, N. V., Gherghiceanu, M., Popescu, L. M. & Das, D. K., febr. 1 2009, In : Journal of Cellular and Molecular Medicine. 13, 2, p. 373-387 15 p.

Research output: Article

115 Citations (Scopus)

Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol

Mukherjee, S., Lekli, I., Gurusamy, N., Bertelli, A. A. A. & Das, D. K., márc. 1 2009, In : Free Radical Biology and Medicine. 46, 5, p. 573-578 6 p.

Research output: Article

102 Citations (Scopus)

Freshly Crushed Garlic is a Superior Cardioprotective Agent than Processed Garlic

Mukherjee, S., Lekli, I., Goswami, S. & Das, D. K., aug. 12 2009, In : Journal of Agricultural and Food Chemistry. 57, 15, p. 7137-7144 8 p.

Research output: Article

28 Citations (Scopus)

Inhibition of Ref-1 stimulates the production of reactive oxygen species and induces differentiation in adult cardiac stem cells

Gurusamy, N., Mukherjee, S., Lekli, I., Bearzi, C., Bardelli, S. & Das, D. K., márc. 1 2009, In : Antioxidants and Redox Signaling. 11, 3, p. 589-599 11 p.

Research output: Article

26 Citations (Scopus)

Potential role of Borreria hispida in ameliorating cardiovascular risk factors

Vasanthi, H. R., Mukherjee, S., Lekli, I., Ray, D., Veeraraghavan, G. & Das, D. K., jún. 1 2009, In : Journal of cardiovascular pharmacology. 53, 6, p. 499-506 8 p.

Research output: Article

12 Citations (Scopus)

Redox regulation of cell survival by the thioredoxin superfamily: An implication of redox gene therapy in the heart

Ahsan, M. K., Lekli, I., Ray, D., Yodoi, J. & Das, D. K., nov. 1 2009, In : Antioxidants and Redox Signaling. 11, 11, p. 2741-2758 18 p.

Research output: Review article

74 Citations (Scopus)

Redox regulation of stem cell mobilization

Lekli, I., Gurusamy, N., Ray, D., Tosaki, A. & Das, D. K., dec. 1 2009, In : Canadian journal of physiology and pharmacology. 87, 12, p. 989-995 7 p.

Research output: Article

20 Citations (Scopus)
2008

Cardioprotection with palm oil tocotrienols: Comparision of different isomers

Das, S., Lekli, I., Das, M., Szabo, G., Varadi, J., Juhasz, B., Bak, I., Nesaretam, K., Tosaki, A., Powell, S. R. & Das, D. K., febr. 1 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 294, 2, p. H970-H978

Research output: Article

59 Citations (Scopus)
48 Citations (Scopus)

Coenzyme Q9 provides cardioprotection after converting into coenzyme Q10

Lekli, I., Das, S., Das, S., Mukherjee, S., Bak, I., Juhasz, B., Bagchi, D., Trimurtulu, G., Krishnaraju, A. V., Sengupta, K., Tosaki, A. & Das, D. K., júl. 9 2008, In : Journal of Agricultural and Food Chemistry. 56, 13, p. 5331-5337 7 p.

Research output: Article

13 Citations (Scopus)