• 13166 Citations
  • 40 h-Index
1973 …2020

Research output per year

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Research Output

Article

Features, genetics and in vivo importance of lymphocyte mediated natural cytotoxicity.

Petrányi, G. G., Györffy, G., Benczur, M., Varga, M., Gyódi, E., Onody, K., Füst, G. & Láng, I., jan. 1 1978, In : Panminerva medica. 20, 1, p. 71-80 10 p.

Research output: Article

2 Citations (Scopus)

Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: Update of study BIG 1-98

Coates, A. S., Keshaviah, A., Thürlimann, B., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R., Castiglione-Gertsch, M., Gelber, R. D., Colleoni, M., Láng, I., Del Mastro, L., Smith, I., Chirgwin, J., Nogaret, J. M., Pienkowski, T., Wardley, A., Jakobsen, E. H., Price, K. N. & Goldhirsch, A., febr. 10 2007, In : Journal of Clinical Oncology. 25, 5, p. 486-492 7 p.

Research output: Article

741 Citations (Scopus)

Free radicals in tissue damage in liver disease and therapeutic approach

Feher, J., Lang, I., Deak, G., Cornides, A., Nekam, K. & Gergely, P., dec. 1 1986, In : Tokai Journal of Experimental and Clinical Medicine. 11, SUPPL., p. 121-134 14 p.

Research output: Article

9 Citations (Scopus)

Genetic changes of p53, K-ras, and microsatellite instability in gallbladder carcinoma in high-incidence areas of Japan and Hungary

Nagahashi, M., Ajioka, Y., Lang, I., Szentirmay, Z., Kasler, M., Nakadaira, H., Yokoyama, N., Watanabe, G., Nishikura, K., Wakai, T., Shirai, Y., Hatakeyama, K. & Yamamoto, M., jan. 7 2008, In : World journal of gastroenterology. 14, 1, p. 70-75 6 p.

Research output: Article

47 Citations (Scopus)

Glutaurine enhances the depressed NK cell activity of tumor patients

Lang, I., Feuer, L., Nekam, K., Szigeti, A., Gergely, P. & Petrányi, G., dec. 1 1983, In : Immunological Communications. 12, 5, p. 519-527 9 p.

Research output: Article

1 Citation (Scopus)

Hemodialízis hatása urémiás betegek antitest-dependens és természetes citotoxicitására.

Láng, I., Taraba, I. & Hering, A., márc. 6 1983, In : Orvosi hetilap. 124, 10, p. 559-562 4 p.

Research output: Article

Hepatoprotective and immunological effects of antioxidant drugs

Lang, I., Nekam, K., Gonzalez-Cabello, R., Muzes, G., Gergely, P. & Feher, J., dec. 1 1990, In : Tokai Journal of Experimental and Clinical Medicine. 15, 2-3, p. 123-127 5 p.

Research output: Article

27 Citations (Scopus)

Hepatoprotective and immunomodulatory effects of antioxidant therapy

Lang, I., Deak, G. Y., Nekam, K., Muzes, G. Y., Gonzalez-Cabello, R., Gergely, P. & Feher, J., dec. 1 1988, In : Acta medica Hungarica. 45, 3-4, p. 287-295 9 p.

Research output: Article

20 Citations (Scopus)

Immune responsiveness of patients with autoimmune diseases and immunodeficiency.

Gergely, P., Láng, I., Nékám, K., Kalmár, L., Török, K., Lévai, J., Gonzales-Cabello, R. & Petrányi, G., dec. 1 1979, In : Annales immunologiae Hungaricae. 19, p. 105-115 11 p.

Research output: Article

Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients

For the Central and East European Oncology Group (CEEOG), 2016, In : Oncotarget. 7, 1, p. 550-564 15 p.

Research output: Article

6 Citations (Scopus)

Immunomodulation in autoimmune diseases

Gergely, P., Lang, I., Gonzalez-Cabello, R. & Feher, J., dec. 1 1986, In : Tokai Journal of Experimental and Clinical Medicine. 11, SUPPL., p. 207-213 7 p.

Research output: Article

6 Citations (Scopus)

Immunomodulatory and hepatoprotective effects of in vivo treatment with free radical scavengers

Lang, I., Nekam, K., Deak, G., Muzes, G., Gonzales-Cabello, R., Gergely, P., Csomos, G. & Feher, J., jan. 1 1990, In : Italian Journal of Gastroenterology. 22, 5, p. 283-287 5 p.

Research output: Article

24 Citations (Scopus)

Immunoreactiv insulin vizsgálatok.

Balázsi, I., Stützel, M., Littmann, L. & Láng, I., jan. 14 1973, In : Orvosi hetilap. 114, 2, 1 p.

Research output: Article

Impact of palbociclib plus letrozole on pain severity and pain interference with daily activities in patients with estrogen receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer as first-line treatment

Bell, T., Crown, J. P., Lang, I., Bhattacharyya, H., Zanotti, G., Randolph, S., Kim, S., Huang, X., Huang Bartlett, C., Finn, R. S. & Slamon, D., máj. 3 2016, In : Current Medical Research and Opinion. 32, 5, p. 959-965 7 p.

Research output: Article

13 Citations (Scopus)

Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab

Budai, B., Komlósi, V., Adleff, V., Pap, É., Réti, A., Nagy, T., Kralovánszky, J., Láng, I. & Hitre, E., jan. 2012, In : Pharmacogenetics and Genomics. 22, 1, p. 69-72 4 p.

Research output: Article

15 Citations (Scopus)

Indomethacin abrogates the suppression by cyclosporin A of lectin-dependent cell-mediated cytotoxicity to HEp-2 cells

Perl, A., Láng, I., Gonzalez-Cabello, R., Filep, J., Nékám, K., Gergely, P. & Fehér, J., febr. 1986, In : Immunopharmacology. 11, 1, p. 39-45 7 p.

Research output: Article

3 Citations (Scopus)
5 Citations (Scopus)

Influence of thymidylate synthase gene polymorphisms on the survival of colorectal cancer patients receiving adjuvant 5-fluorouracil

Hitre, E., Budai, B., Adleff, V., Czeglédi, F., Horváth, Z., Gyergyay, F., Lövey, J., Kovács, T., Orosz, Z., Láng, I., Kásler, M. & Kralovánszky, J., okt. 2005, In : Pharmacogenetics and Genomics. 15, 10, p. 723-730 8 p.

Research output: Article

64 Citations (Scopus)
9 Citations (Scopus)

In vitro effect of immune complex positive human sera on antibody dependent cellular cytotoxicity

Lang, I., Torok, K., Fekete, B., Gergely, P. & Petrányi, G., dec. 1 1977, In : Acta medica Academiae Scientiarum Hungaricae. 34, 3, p. 117-121 5 p.

Research output: Article

In vitro effect of transfer factor on active rosettes and leucocyte migration of patients with cancer

Nekam, K., Kalmar, L., Gergely, P., Kelemen, G., Fekete, B., Láng, I., Lévai, J. & Petrányi, G. Y., okt. 23 1977, In : Clinical and Experimental Immunology. 27, 3, p. 416-420 5 p.

Research output: Article

5 Citations (Scopus)

Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015

Köhne, C. H., De greve, J., Hartmann, J. T., Lang, I., Vergauwe, P., Becker, K., Braumann, D., Joosens, E., Müller, L., Janssens, J., Bokemeyer, C., Reimer, P., Link, H., Späth-Schwalbe, E., Wilke, H. J., Bleiberg, H., Van den Brande, J., Debois, M., Bethe, U. & Van Cutsem, E., máj. 2008, In : Annals of Oncology. 19, 5, p. 920-926 7 p.

Research output: Article

124 Citations (Scopus)

Isoprinosine: Mechanism of the therapeutic effect and trial in recurrent herpes

Nekam, K., Torok, K. & Lang, I., jan. 1 1980, In : Orvosi hetilap. 121, 23, p. 1393-1395 3 p.

Research output: Article

Is risk of central nervous system (CNS) relapse related to adjuvant taxane treatment in node-positive breast cancer? Results of the CNS substudy in the intergroup phase III BIG 02-98 trial

Pestalozzi, B. C., Francis, P., Quinaux, E., Dolci, S., Azambuja, E., Gelber, R. D., Viale, G., Balil, A., Andersson, M., Nordenskjöd, B., Gnant, M., Gutierrez, J., Láng, I., Crown, J. P. A. & Piccart-Gebhart, M., 2008, In : Annals of Oncology. 19, 11, p. 1837-1841 5 p.

Research output: Article

15 Citations (Scopus)
19 Citations (Scopus)

Lapatinib-related rash and breast cancer outcome in the ALTTO phase III randomized trial

Sonnenblick, A., De Azambuja, E., Agbor-Tarh, D., Bradbury, I., Campbell, C., Huang, Y., Dueck, A. C., Pritchard, K. I., Wolff, A. C., Jackisch, C., Lang, I., Untch, M., Smith, I., Boyle, F., Xu, B., Gomez, H., Perez, E. A., Piccart, M. & Azim, H. A., 2016, In : Journal of the National Cancer Institute. 108, 8, djw037.

Research output: Article

14 Citations (Scopus)
2 Citations (Scopus)

Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): Survival outcomes of a randomised, open-label, multicentre, phase 3 trial and their association with pathological complete response

De Azambuja, E., Holmes, A. P., Piccart-Gebhart, M., Holmes, E., Di Cosimo, S., Swaby, R. F., Untch, M., Jackisch, C., Lang, I., Smith, I., Boyle, F., Xu, B., Barrios, C. H., Perez, E. A., Azim, H. A., Kim, S. B., Kuemmel, S., Huang, C. S., Vuylsteke, P., Hsieh, R. K. & 7 others, Gorbunova, V., Eniu, A., Dreosti, L., Tavartkiladze, N., Gelber, R. D., Eidtmann, H. & Baselga, J., jan. 1 2014, In : The Lancet Oncology. 15, 10, p. 1137-1146 10 p.

Research output: Article

259 Citations (Scopus)

Lectin-dependent cell-mediated cytotoxicity and blastogenesis by large granular-enriched and depleted lymphocytes

Perl, A., Gonzalez-Cabello, R., Laskay, T., Benczur, M., Láng, I., Onódy, K., Nékám, K., Gergely, P. & Fehér, J., márc. 19 1986, In : Clinical and Experimental Immunology. 63, 1, p. 171-178 8 p.

Research output: Article

Lectin induced suppression of antibody dependent cellular cytotoxicity (ADCC) of human peripheral blood mononuclear cells

Gergely, P., Lang, I., Kalmar, L. & Gonzalez Cabello, R., jan. 1 1980, In : Acta medica Academiae Scientiarum Hungaricae. 37, 4, p. 359-394 36 p.

Research output: Article

4 Citations (Scopus)

Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: The BIG 1-98 trial

Crivellari, D., Sun, Z., Coates, A. S., Price, K. N., Thürlimann, B., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R. J., Castiglione-Gertsch, M., Gelber, R. D., Colleoni, M., Láng, I., Del Mastro, L., Gladieff, L., Rabaglio, M., Smith, I. E., Chirgwin, J. H. & Goldhirsch, A., jan. 1 2008, In : Journal of Clinical Oncology. 26, 12, p. 1972-1979 8 p.

Research output: Article

116 Citations (Scopus)

Litoralon kezelés hatása rosszindulatú daganatos betegek lymphocitotoxicitására.

Láng, I., Feuer, L., Nékám, K., Perl, A., Szigeti, A., Gergely, P. & Fehér, J., szept. 2 1984, In : Orvosi hetilap. 125, 36, p. 2193-2196 4 p.

Research output: Article

Liver cell protection in toxic liver lesion

Feher, J., Cornides, A., Pal, J., Lang, I. & Csomos, G., dec. 1 1989, In : Acta physiologica Hungarica. 73, 2-3, p. 285-291 7 p.

Research output: Article

6 Citations (Scopus)

Long-term cardiac outcomes of patients with HER2-positive breast cancer treated in the adjuvant lapatinib and/or trastuzumab Treatment Optimization Trial

Eiger, D., Pondé, N. F., Agbor-Tarh, D., Moreno-Aspitia, A., Piccart, M., Hilbers, F. S., Werner, O., Chumsri, S., Dueck, A., Kroep, J. R., Gomez, H., Láng, I., Rodeheffer, R. J., Ewer, M. S., Suter, T. & de Azambuja, E., máj. 12 2020, In : British journal of cancer. 122, 10, p. 1453-1460 8 p.

Research output: Article

Low-dose oral cyclophosphamide and methotrexate maintenance for hormone receptor-negative early breast cancer: International Breast Cancer Study Group Trial 22-00

Colleoni, M., Gray, K. P., Gelber, S., Láng, I., Thürlimann, B., Gianni, L., Abdi, E. A., Gomez, H. L., Linderholm, B. K., Puglisi, F., Tondini, C., Kralidis, E., Eniu, A., Cagossi, K., Rauch, D., Chirgwin, J., Gelber, R. D., Regan, M. M., Coates, A. S., Price, K. N. & 2 others, Viale, G. & Goldhirsch, A., okt. 1 2016, In : Journal of Clinical Oncology. 34, 28, p. 3400-3408 9 p.

Research output: Article

40 Citations (Scopus)

Lymphogranulomatosisos betegek K (killer) sejt aktivitása.

Láng, I., Berényi, E., Szegedi, G., Fekete, B., Török, K., Kalmár, L. & Nékám, K., szept. 10 1978, In : Orvosi hetilap. 119, 37, p. 2249-2250 2 p.

Research output: Article

1 Citation (Scopus)

Metothyrin indukált agranulocytosis kezelése granulocyta-macrophag colonia stimuláló faktorral.

Somogyi, A., Werling, K., Rosta, A. & Láng, I., nov. 6 1994, In : Orvosi hetilap. 135, 45, p. 2483-2485 3 p.

Research output: Article

Motesanib, or open-label bevacizumab, in combination with paclitaxel, as first-line treatment for HER2-negative locally recurrent or metastatic breast cancer: A phase 2, randomised, double-blind, placebo-controlled study

Martin, M., Roche, H., Pinter, T., Crown, J., Kennedy, M. J., Provencher, L., Priou, F., Eiermann, W., Adrover, E., Lang, I., Ramos, M., Latreille, J., Jagiełło-Gruszfeld, A., Pienkowski, T., Alba, E., Snyder, R., Almel, S., Rolski, J., Munoz, M., Moroose, R. & 9 others, Hurvitz, S., Baños, A., Adewoye, H., Hei, Y. J., Lindsay, M. A., Rupin, M., Cabaribere, D., Lemmerick, Y. & Mackey, J. R., ápr. 2011, In : The Lancet Oncology. 12, 4, p. 369-376 8 p.

Research output: Article

72 Citations (Scopus)

Multicenter phase III comparison of cisplatin/S-1 with cisplatin/infusional fluorouracil in advanced gastric or gastroesophageal adenocarcinoma study: The FLAGS trial

Ajani, J. A., Rodriguez, W., Bodoky, G., Moiseyenko, V., Lichinitser, M., Gorbunova, V., Vynnychenko, I., Garin, A., Lang, I. & Falcon, S., márc. 20 2010, In : Journal of Clinical Oncology. 28, 9, p. 1547-1553 7 p.

Research output: Article

434 Citations (Scopus)

Mutational analysis of triple-negative breast cancers within the International Breast Cancer Study Group (IBCSG) Trial 22-00

Munzone, E., Gray, K. P., Fumagalli, C., Guerini-Rocco, E., Láng, I., Ruhstaller, T., Gianni, L., Kammler, R., Viale, G., Di Leo, A., Coates, A. S., Gelber, R. D., Regan, M. M., Goldhirsch, A., Barberis, M. & Colleoni, M., júl. 1 2018, In : Breast Cancer Research and Treatment. 170, 2, p. 351-360 10 p.

Research output: Article

2 Citations (Scopus)

Myasthenia in a patient with sarcoidosis and schizophrenia.

Rózsa, C., Kis, G., Komoly, S., Anselmo, V., Esik, O., Láng, I., Kas, J., Németh, G., Solymosi, D., Svasztics, E., Szentirmay, Z., Szobor, A. & Telekes, A., júl. 20 2004, In : Ideggyógyászati szemle. 57, 7-8, p. 242-244 3 p.

Research output: Article

5 Citations (Scopus)

Null-sejtes Sezary-syndroma.

Szigeti, A., Fazakas, L., Fekete, B., Nékám, K., Láng, I. & Gergely, P., júl. 29 1979, In : Orvosi hetilap. 120, 30, p. 1825-1827 3 p.

Research output: Article

O{double acute}rszemnyirokcsomó-biopszia neoadjuváns kemoterápiát igénylo{double acute} emlo{double acute}rákoknál

Mátrai, Z., Tóth, L., Polgár, C., Láng, I., Godény, M., Sinkovics, I., Horváth, Z., Bidlek, M., Udvarhelyi, N., Bartal, A., Sávolt, Á., Újhelyi, M. & Kásler, M., 2011, In : Magyar onkologia. 55, 2, p. 73-84 12 p.

Research output: Article

1 Citation (Scopus)

Obesity and risk of recurrence or death after adjuvant endocrine therapy with letrozole or tamoxifen in the breast international group 1-98 trial

Ewertz, M., Gray, K. P., Regan, M. M., Ejlertsen, B., Price, K. N., Thürlimann, B., Bonnefoi, H., Forbes, J. F., Paridaens, R. J., Rabaglio, M., Gelber, R. D., Colleoni, M., Láng, I., Smith, I. E., Coates, A. S., Goldhirsch, A. & Mouridsen, H. T., nov. 10 2012, In : Journal of Clinical Oncology. 30, 32, p. 3967-3975 9 p.

Research output: Article

74 Citations (Scopus)

Phase II study on the efficacy and safety of Lapatinib administered beyond disease progression and combined with vinorelbine in HER-2/neu- positive advanced breast cancer: Results of the CECOG LaVie trial

Thallinger, C., Lang, I., Kuhar, C. G., Bartsch, R., Singer, C. F., Petruzelka, L., Melichar, B., Knittelfelder, R., Brodowicz, T. & Zielinski, C., febr. 18 2016, In : BMC cancer. 16, 1, 121.

Research output: Article

4 Citations (Scopus)