• 12479 Citations
  • 39 h-Index
1973 …2019

Research output per year

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Research Output

2013

Expert opinion 2011 on the use of new anti-resorptive agents in the prevention of skeletal-related events in metastatic bone disease

Anghel, R., Bachmann, A., Bekşac, M., Brodowicz, T., Finek, J., Komadina, R., Krzemieniecki, K., Lang, I., Marencak, J., Von Moos, R., Pecherstorfer, M., Rordorf, T., Vrbanec, D. & Zielinski, C., aug. 1 2013, In : Wiener Klinische Wochenschrift. 125, 15-16, p. 439-447 9 p.

Research output: Review article

4 Citations (Scopus)

Preoperatív kemoterápia a colorectalis májáttétes betegek sebészi kezelésében

Dede, K., Láng, I., Pörneczi, B., Mester, G., Fekete, A., Kőszegi, G., Mersich, T., Besznyák, I. & Bursics, A., dec. 1 2013, In : Magyar sebészet. 66, 6, p. 325-330 6 p.

Research output: Article

1 Citation (Scopus)

Quality of life analysis in patients with KRAS wild-type metastatic colorectal cancer treated first-line with cetuximab plus irinotecan, fluorouracil and leucovorin

Láng, I., Köhne, C. H., Folprecht, G., Rougier, P., Curran, D., Hitre, E., Sartorius, U., Griebsch, I. & Van Cutsem, E., jan. 1 2013, In : European Journal of Cancer. 49, 2, p. 439-448 10 p.

Research output: Article

41 Citations (Scopus)
8 Citations (Scopus)
6 Citations (Scopus)
2012

A hanging manover újabb indikációi a májsebészetben.

Jakab, F., Dede, K., Láng, I., Bursics, A. & Mersich, T., dec. 2012, In : Magyar sebészet. 65, 6, p. 407-415 9 p.

Research output: Article

1 Citation (Scopus)

A phase II multicenter study of two different dosages of pemetrexed given in combination with cyclophosphamide as first-line treatment in patients with locally advanced or metastatic breast cancer

Dittrich, C., Solska, E., Manikhas, A., Eniu, A., Tjulandin, S., Anghel, R., Musib, L., Frimodt-Moller, B., Liu, Y., Krejcy, K. & Láng, I., máj. 1 2012, In : Cancer Investigation. 30, 4, p. 309-316 8 p.

Research output: Article

4 Citations (Scopus)

Az emlorák korszeru gyógyszeres kezelése

Láng, I., Kahán, Z., Hitre, E., Dank, M., Rubovszky, G., Horváth, Z. & Kásler, M., jan. 1 2012, In : Orvosi hetilap. 153, 2, p. 56-65 10 p.

Research output: Article

3 Citations (Scopus)

Az emlorák korszeru képalkotó diagnosztikája: nukleárismedicina-technikák

Katalin, B., István, S., Balázs, M., Zsolt, H., István, L. & Miklós, K., jan. 1 2012, In : Orvosi hetilap. 153, 1, p. 14-21 8 p.

Research output: Article

Az MR-vizsgálat szerepe a rectumcarcinomák terápiájának meghatározásában

Jederán, É., Mátrai, Z., Tóth, L., Lövey, J., Láng, I., Hitre, E., Naszádos, G. & Godény, M., 2012, In : Magyar onkologia. 56, 3, p. 179-186 8 p.

Research output: Article

1 Citation (Scopus)

Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab

Budai, B., Komlósi, V., Adleff, V., Pap, É., Réti, A., Nagy, T., Kralovánszky, J., Láng, I. & Hitre, E., jan. 1 2012, In : Pharmacogenetics and Genomics. 22, 1, p. 69-72 4 p.

Research output: Article

14 Citations (Scopus)

Obesity and risk of recurrence or death after adjuvant endocrine therapy with letrozole or tamoxifen in the breast international group 1-98 trial

Ewertz, M., Gray, K. P., Regan, M. M., Ejlertsen, B., Price, K. N., Thürlimann, B., Bonnefoi, H., Forbes, J. F., Paridaens, R. J., Rabaglio, M., Gelber, R. D., Colleoni, M., Láng, I., Smith, I. E., Coates, A. S., Goldhirsch, A. & Mouridsen, H. T., nov. 10 2012, In : Journal of Clinical Oncology. 30, 32, p. 3967-3975 9 p.

Research output: Article

66 Citations (Scopus)

Safety results from a phase III study (TURANDOT trial by CECOG) of first-line bevacizumab in combination with capecitabine or paclitaxel for HER-2-negative locally recurrent or metastatic breast cancer

Lang, I., Inbar, M. J., Kahán, Z., Greil, R., Beslija, S., Stemmer, S. M., Kaufman, B., Zvirbule, Z., Steger, G. G., Messinger, D., Brodowicz, T. & Zielinski, C., nov. 1 2012, In : European Journal of Cancer. 48, 17, p. 3140-3149 10 p.

Research output: Article

11 Citations (Scopus)

Significance of histomorphology of early triple-negative breast cancer

Rubovszky, G., Horváth, Z., Tóth, E., Láng, I. & Kásler, M., okt. 1 2012, In : Pathology and Oncology Research. 18, 4, p. 823-831 9 p.

Research output: Article

2 Citations (Scopus)

Vandetanib with docetaxel as second-line treatment for advanced breast cancer: A double-blind, placebo-controlled, randomized Phase II study

Boér, K., Láng, I., Llombart-Cussac, A., Andreasson, I., Vivanco, G. L., Sanders, N., Pover, G. M. & Murray, E., ápr. 1 2012, In : Investigational New Drugs. 30, 2, p. 681-687 7 p.

Research output: Article

33 Citations (Scopus)
2011

A modern emlo{double acute}sebészet onkoplasztikai kihívásai

Mátrai, Z., Gulyás, G., Tóth, L., Polgár, C., Bidlek, M., Szabó, É., Láng, I., Horváth, Z., Udvarhelyi, N., Kunos, C., Sávolt, Á., Pesthy, P. & Kásler, M., 2011, In : Magyar onkologia. 55, 1, p. 40-52 13 p.

Research output: Article

8 Citations (Scopus)

Analyses adjusting for selective crossover show improved overall survival with adjuvant letrozole compared with tamoxifen in the BIG 1-98 study

Colleoni, M., Giobbie-Hurder, A., Regan, M. M., Thürlimann, B., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R., Láng, I., Smith, I., Chirgwin, J., Pienkowski, T., Wardley, A., Price, K. N., Gelber, R. D., Coates, A. S. & Goldhirsch, A., márc. 20 2011, In : Journal of Clinical Oncology. 29, 9, p. 1117-1124 8 p.

Research output: Article

100 Citations (Scopus)

A Phase II, open-label, randomised study to assess the efficacy and safety of the MEK1/2 inhibitor AZD6244 (ARRY-142886) versus capecitabine monotherapy in patients with colorectal cancer who have failed one or two prior chemotherapeutic regimens

Bennouna, J., Lang, I., Valladares-Ayerbes, M., Boer, K., Adenis, A., Escudero, P., Kim, T. Y., Pover, G. M., Morris, C. D. & Douillard, J. Y., okt. 1 2011, In : Investigational New Drugs. 29, 5, p. 1021-1028 8 p.

Research output: Article

93 Citations (Scopus)

Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: The BIG 1-98 randomised clinical trial at 8·1 years median follow-up

Regan, M. M., Neven, P., Giobbie-Hurder, A., Goldhirsch, A., Ejlertsen, B., Mauriac, L., Forbes, J. F., Smith, I., Láng, I., Wardley, A., Rabaglio, M., Price, K. N., Gelber, R. D., Coates, A. S. & Thürlimann, B., nov. 1 2011, In : The Lancet Oncology. 12, 12, p. 1101-1108 8 p.

Research output: Article

261 Citations (Scopus)

Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status

Van Cutsem, E., Köhne, C. H., Láng, I., Folprecht, G., Nowacki, M. P., Cascinu, S., Shchepotin, I., Maurel, J., Cunningham, D., Tejpar, S., Schlichting, M., Zubel, A., Celik, I., Rougier, P. & Ciardiello, F., máj. 20 2011, In : Journal of Clinical Oncology. 29, 15, p. 2011-2019 9 p.

Research output: Article

1247 Citations (Scopus)
5 Citations (Scopus)

Motesanib, or open-label bevacizumab, in combination with paclitaxel, as first-line treatment for HER2-negative locally recurrent or metastatic breast cancer: A phase 2, randomised, double-blind, placebo-controlled study

Martin, M., Roche, H., Pinter, T., Crown, J., Kennedy, M. J., Provencher, L., Priou, F., Eiermann, W., Adrover, E., Lang, I., Ramos, M., Latreille, J., Jagiełło-Gruszfeld, A., Pienkowski, T., Alba, E., Snyder, R., Almel, S., Rolski, J., Munoz, M., Moroose, R. & 9 others, Hurvitz, S., Baños, A., Adewoye, H., Hei, Y. J., Lindsay, M. A., Rupin, M., Cabaribere, D., Lemmerick, Y. & Mackey, J. R., ápr. 2011, In : The Lancet Oncology. 12, 4, p. 369-376 8 p.

Research output: Article

70 Citations (Scopus)

O{double acute}rszemnyirokcsomó-biopszia neoadjuváns kemoterápiát igénylo{double acute} emlo{double acute}rákoknál

Mátrai, Z., Tóth, L., Polgár, C., Láng, I., Godény, M., Sinkovics, I., Horváth, Z., Bidlek, M., Udvarhelyi, N., Bartal, A., Sávolt, Á., Újhelyi, M. & Kásler, M., 2011, In : Magyar onkologia. 55, 2, p. 73-84 12 p.

Research output: Article

1 Citation (Scopus)

The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer

Afzal, S., Gusella, M., Jensen, S. A., Vainer, B., Vogel, U., Andersen, J. T., Brødbæk, K., Petersen, M., Jimenez-Solem, E., Adleff, V., Budai, B., Hitre, E., Lng, I., Orosz, E., Bertolaso, L., Barile, C., Padrini, R., Kralovnszky, J., Pasini, F. & Poulsen, H. E., szept. 1 2011, In : Pharmacogenomics. 12, 9, p. 1257-1267 11 p.

Research output: Article

27 Citations (Scopus)

Which patients benefit most from adjuvant aromatase inhibitors? Results using a composite measure of prognostic risk in the BIG 1-98 randomized trial

Viale, G., Regan, M. M., Dell'Orto, P., Mastropasqua, M. G., Maiorano, E., Rasmussen, B. B., MacGrogan, G., Forbes, J. F., Paridaens, R. J., Colleoni, M., Láng, I., Thürlimann, B., Mouridsen, H., Mauriac, L., Gelber, R. D., Price, K. N., Goldhirsch, A., Gusterson, B. A. & Coates, A. S., okt. 2011, In : Annals of Oncology. 22, 10, p. 2201-2207 7 p.

Research output: Article

67 Citations (Scopus)
2010

A tripla-negatív emlokarcinóma - Irodalmi áttekintés

Rubovszky, G., Udvarhelyi, N., Horváth, Z., Láng, I. & Kásler, M., dec. 1 2010, In : Magyar onkologia. 54, 4, p. 325-335 11 p.

Research output: Article

4 Citations (Scopus)

Az emloárák belgyógyászati onkológiai (gyógyszeres) kezelése

Láng, I., Kahán, Z., Pintér, T., Dank, M., Boér, K., Pajkos, G., Faluhelyi, Z., Pikó, B., Eckhardt, S. & Horváth, Z., szept. 1 2010, In : Magyar onkologia. 54, 3, p. 237-254 18 p.

Research output: Article

12 Citations (Scopus)

Multicenter phase III comparison of cisplatin/S-1 with cisplatin/infusional fluorouracil in advanced gastric or gastroesophageal adenocarcinoma study: The FLAGS trial

Ajani, J. A., Rodriguez, W., Bodoky, G., Moiseyenko, V., Lichinitser, M., Gorbunova, V., Vynnychenko, I., Garin, A., Lang, I. & Falcon, S., márc. 20 2010, In : Journal of Clinical Oncology. 28, 9, p. 1547-1553 7 p.

Research output: Article

422 Citations (Scopus)
2009

A Case-Control Study of Gallbladder Cancer in Hungary

Nakadaira, H., Lang, I., Szentirmay, Z., Hitre, E., Kaster, M. & Yamamoto, M., 2009, In : Asian Pacific Journal of Cancer Prevention. 10, 5, p. 833-836 4 p.

Research output: Article

11 Citations (Scopus)

Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG 1-98 trial

Rabaglio, M., Sun, Z., Price, K. N., Castiglione-Gertsch, M., Hawle, H., Thürlimann, B., Mouridsen, H., Campone, M., Forbes, J. F., Paridaens, R. J., Colleoni, M., Pienkowski, T., Nogaret, J. M., Láng, I., Smith, I., Gelber, R. D., Goldhirsch, A. & Coates, A. S., jan. 1 2009, In : Annals of Oncology. 20, 9, p. 1489-1498 10 p.

Research output: Article

106 Citations (Scopus)
2008

A biszfo szfo nát-keze lés során és zlelhet o vese funkci ó-válto zás vizsg álata emlorákos betege inknél

Horváth, Z., Farkas, P., Ganofszky, E., Hitre, E., Juhos, É., Nagy, T., Rubovszky, G., Szabó, E. & Láng, I., dec. 1 2008, In : Magyar onkologia. 52, 1, p. 49-55 7 p.

Research output: Article

Adjuvant chemotherapy with sequential or concurrent anthracycline and docetaxel: Breast International Group 02-98 randomized trial

Francis, P., Crown, J., Di Leo, A., Buyse, M., Balil, A., Andersson, M., Nordenskjöld, B., Lang, I., Jakesz, R., Vorobiof, D., Gutiérrez, J., Van Hazel, G., Dolci, S., Jamin, S., Bendahmane, B., Gelber, R. D., Goldhirsch, A., Castiglione-Gertsch, M. & Piccart-Gebhart, M., jan. 2008, In : Journal of the National Cancer Institute. 100, 2, p. 121-133 13 p.

Research output: Article

125 Citations (Scopus)
4 Citations (Scopus)

Effect of genetic predisposition on the risk of gallbladder cancer in Hungary

Kimura, A., Tsuchiya, Y., Lang, I., Zoltan, S., Nakadaira, H., Ajioka, Y., Kiyohara, C., Oyama, M., Nakamura, K. & Yamamoto, M., 2008, In : Asian Pacific Journal of Cancer Prevention. 9, 3, p. 391-396 6 p.

Research output: Article

15 Citations (Scopus)

Genetic changes of p53, K-ras, and microsatellite instability in gallbladder carcinoma in high-incidence areas of Japan and Hungary

Nagahashi, M., Ajioka, Y., Lang, I., Szentirmay, Z., Kasler, M., Nakadaira, H., Yokoyama, N., Watanabe, G., Nishikura, K., Wakai, T., Shirai, Y., Hatakeyama, K. & Yamamoto, M., jan. 7 2008, In : World journal of gastroenterology. 14, 1, p. 70-75 6 p.

Research output: Article

46 Citations (Scopus)

Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015

Köhne, C. H., De greve, J., Hartmann, J. T., Lang, I., Vergauwe, P., Becker, K., Braumann, D., Joosens, E., Müller, L., Janssens, J., Bokemeyer, C., Reimer, P., Link, H., Späth-Schwalbe, E., Wilke, H. J., Bleiberg, H., Van den Brande, J., Debois, M., Bethe, U. & Van Cutsem, E., máj. 1 2008, In : Annals of Oncology. 19, 5, p. 920-926 7 p.

Research output: Article

124 Citations (Scopus)

Is risk of central nervous system (CNS) relapse related to adjuvant taxane treatment in node-positive breast cancer? Results of the CNS substudy in the intergroup phase III BIG 02-98 trial

Pestalozzi, B. C., Francis, P., Quinaux, E., Dolci, S., Azambuja, E., Gelber, R. D., Viale, G., Balil, A., Andersson, M., Nordenskjöd, B., Gnant, M., Gutierrez, J., Láng, I., Crown, J. P. A. & Piccart-Gebhart, M., nov. 3 2008, In : Annals of Oncology. 19, 11, p. 1837-1841 5 p.

Research output: Article

15 Citations (Scopus)

Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: The BIG 1-98 trial

Crivellari, D., Sun, Z., Coates, A. S., Price, K. N., Thürlimann, B., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R. J., Castiglione-Gertsch, M., Gelber, R. D., Colleoni, M., Láng, I., Del Mastro, L., Gladieff, L., Rabaglio, M., Smith, I. E., Chirgwin, J. H. & Goldhirsch, A., jan. 1 2008, In : Journal of Clinical Oncology. 26, 12, p. 1972-1979 8 p.

Research output: Article

113 Citations (Scopus)

Progress on BIG 1-02/IBCSG 27-02/NSABP B-37, a prospective randomized trial evaluating chemotherapy after local therapy for isolated locoregional recurrences of breast cancer

Wapnir, I. L., Aebi, S., Gelber, S., Anderson, S. J., Láng, I., Robidoux, A., Mamounas, E. P. & Wolmark, N., nov. 1 2008, In : Annals of Surgical Oncology. 15, 11, p. 3227-3231 5 p.

Research output: Article

23 Citations (Scopus)

Sebészi onkológia

Ferenc, J. & István, L., dec. 15 2008, In : Orvoskepzes. 83, 3, p. 281-285 5 p.

Research output: Review article

2007

Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: Update of study BIG 1-98

Coates, A. S., Keshaviah, A., Thürlimann, B., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R., Castiglione-Gertsch, M., Gelber, R. D., Colleoni, M., Láng, I., Del Mastro, L., Smith, I., Chirgwin, J., Nogaret, J. M., Pienkowski, T., Wardley, A., Jakobsen, E. H., Price, K. N. & Goldhirsch, A., febr. 10 2007, In : Journal of Clinical Oncology. 25, 5, p. 486-492 7 p.

Research output: Article

732 Citations (Scopus)
2 Citations (Scopus)

Predictors of early relapse in postmenopausal women with hormone receptor-positive breast cancer in the BIG 1-98 trial

Mauriac, L., Keshaviah, A., Debled, M., Mouridsen, H., Forbes, J. F., Thürlimann, B., Paridaens, R., Monnier, A., Láng, I., Wardley, A., Nogaret, J. M., Gelber, R. D., Castiglione-Gertsch, M., Price, K. N., Coates, A. S., Smith, I., Viale, G., Rabaglio, M., Zabaznyi, N. & Goldhirsch, A., máj. 2007, In : Annals of Oncology. 18, 5, p. 859-867 9 p.

Research output: Article

112 Citations (Scopus)

Radio-guided resection of non-palpable rectal carcinoma following polypectomy

Mersich, T., Lang, I., Balogh, I. & Jakob, F., ápr. 1 2007, In : Hepato-Gastroenterology. 54, 75, p. 751-752 2 p.

Research output: Article

2006

The neo-adjuvant, surgical and adjuvant treatment of gastric adenocarcinoma. Current expert opinion derived from the Seventh World Congress on Gastrointestinal Cancer, Barcelona, 2005

Van Cutsem, E., Dicato, M., Arber, N., Benson, A., Cunningham, D., Diaz-Rubio, E., Glimelius, B., Goldberg, R., Haller, D., Haustermans, K., Koo-Kang, Y., Labianca, R., Lang, I., Minsky, B., Nordlinger, B., Roth, A., Rougier, P., Schmoll, H. J., Sobrero, A., Tabernero, J. & 2 others, Szawlowski, A. & van de Velde, C., jún. 1 2006, In : Annals of Oncology. 17, SUPPL. 6, p. vi13-vi18

Research output: Article

26 Citations (Scopus)
3 Citations (Scopus)
2005

A gastrointestinalis stroma tumorok (GIST) kezelésének modern szemlélete

Láng, I. & Hitre, E., dec. 1 2005, In : Orvosi hetilap. 146, 18 SUPPL.1, p. 935-941 7 p.

Research output: Review article

1 Citation (Scopus)

Influence of thymidylate synthase gene polymorphisms on the survival of colorectal cancer patients receiving adjuvant 5-fluorouracil

Hitre, E., Budai, B., Adleff, V., Czeglédi, F., Horváth, Z., Gyergyay, F., Lövey, J., Kovács, T., Orosz, Z., Láng, I., Kásler, M. & Kralovánszky, J., okt. 2005, In : Pharmacogenetics and Genomics. 15, 10, p. 723-730 8 p.

Research output: Article

64 Citations (Scopus)